제주도 동남방 신천해안역 해수의 이화학적 특성과 저질분포

최영찬,고기원,김상현 제주대학교 해양연구소 1987 해양자원연구소연구보고 Vol.11 No.-

Ascorbic Acid와 Pyrophosphate로부터 Ascorbic Acid-2-Phosphate의 효소적 생산

최현일,이상협,방원기 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.5

Ascorbic acid (AsA)와 pyrophosphate로부터 ascorbic acid-2-phosphate (AsA2P)를 생산할 수 있는 미생물을 본 실험실에서 분리한 보존 균주로부터 선별하였다. 선별 균주 중에서 Cellulomonas sp. AP-7이 가장 높은 AsA2P 생산능을 나타내었다. 효소원으로 본 균주의 무세포 추출물을 이용하여 AsA와 PPi로부터 AsA2P의 최적 생산 조건을 조사하였다. AsA2P의 최적 생산을 위한 반응 혼합액은 효소원으로 21 mg/ml의 무세포 추출물, 150 mM sodium acetate 완충액(pH 4.5), 기질로 250 mM AsA 그리고 인산 공여체로 200 mM PPi로 조성되었으며, 이 반응 혼합액을 사용하여 33℃에서 48시간 반응시켰을 때, 31.9 mM의 AsA2P가 생산되었으며, 이는 반응에 사용한 AsA에 대해 12.76%의 수율에 해당하였다. Microorganisms capable of producing ascorbic acid-2-phosphate (AsA2P) from ascorbic acid (AsA) and pyrophosphate (PPi) wee screened from the culture collection of this laboratory. Among them Cellulomonas sp. AP-7 showed the highest productivity of AsA2P. The optimal conditions for the production of AsA2P from AsA and PPi with cell-free extract as an enzyme source wee investigated. The reaction mixture for the maximal production of AsA2P consisted of 21 g protein of cell-free extract per liter as the enzyme source, 250 mM AsA, 200 mM sodium pyrophosphate, 150 mM sodium acetate buffer (pH 4.5). By using this reaction mixture, 31.9 mM of AsA2P, which corresponded to a 12.76% yield based on AsA, was produced after incubation of 48 hr at 33℃.

만성 심부전 환자에서의 Denopamine 투여효과

최석구,김현대,정태기,김대현,김용복,유원상 인제대학교 1994 仁濟醫學 Vol.15 No.2

만성 심부전 환자에게 새로운 경구용 비 digitalis 강심제인 denopamine 1T(5mg)을 1일 3회 3개월간 투여하여 그 유효성 및 안전성을 검토했다. Background : Patients with congestive heart failure have a high mortality rate and are also hospitalized frequently. We studied the effects of a new oral inotrophic agent, denopamine in patients with chronic heart failure. Methods : 16 patients receiving conventional treatments for heart failure were treat ed with denopamine 5mg tad for at shortest 3 months. Their history were taken and the physical examination, general laboratory test and the echocardiographic examination were done before and after treatment. Results: There were 3 deaths and 1 withdrawal because of worsening heart failure. 5 patients (42%) among 12 patients showed the improvement in their subjective symptoms. The fractional shortening and ejection fraction of the left ventricle were increased by 3.2% and 5.6% respectively in their absolute values. Conclusion : The addition of denopamine to conventional therapy considerably improved the subjective symptoms and the left ventricular function in the limited number of patients with chronic heart failure.

활동혈압에 의한 Cicletanine의 강압효과 판정

정태기,김현대,류재춘,최석구,유원상 인제대학교 1993 仁濟醫學 Vol.14 No.4

Prostaglandin 합성을 촉진하는 새로운 강압약인 cicletanine의 강압효과를 진료실 혈압과 24시간 활동혈압으로 평가했을 때 상당한 차이를 보여 그 이유를 검토해 보았다. To evaluate antihypertensive effect of cicletanine with both clinic and ambulatory blood pressure monitoring, 10 male hypertensive patients were administered cicletanine, a new antihypertensive stimulating prostaglandin synthesis, in 100∼200 mg daily for 12 weeks. The following were the results. 1.Mean of clinic BP decreased from 161/98 mmHg to 153/98 mmHg. 2.Mean of ambulatory BP changed from 140/91 mmHg to 153/99 mmHg. 3.Side reactions were mild, namely indigestion and constipation. 4.Discrepancy between clinic and ambulatory BP were discussed. In conclusion cicletanine revealed slight antihypertensive effect with clinic blood pressure, but failed to confirm it with ambulatory blood pressure.

치과병원에서 사용되는 진단영상에 대한 JPEG 2000 압축률에 대한 평가

정기훈,한원정,유동수,최순철,김은경 대한구강악안면방사선학회 2005 Imaging Science in Dentistry Vol.35 No.3

Purpose : To find out the proper compression ratios without degrading image quality and affecting lesion detectability on diagnostic images used in dentistry compressed with JPEG 2000 algorithm. Materials and Methods : Sixty Digora periapical images, sixty panoramic computed radiographic (CR) images, sixty computed tomographic (CT) images, and sixty magnetic resonance (MR) images were compressed into JPEG 2000 with ratios of 10 levels from 5 : 1 to 50 : 1. To evaluate the lesion detectability, the images were graded with 5 levels (1: definitely absent; 2: probably absent; 3: equivocal; 4: probably present; 5: definitely present), and then receiver operating characteristic analysis was performed using the original image as a gold standard. Also to evaluate subjectively the image quality, the images were graded with 5 levels (1: definitely unacceptable; 2: probably unacceptable; 3: equivocal; 4: probably acceptable; 5: definitely acceptable), and then paired t-test was performed. Results : In Digora, CR panoramic and CT images, compressed images up to ratios of 15 : 1 showed nearly the same lesion detectability as original images, and in MR images, compressed images did up to ratios of 25 : 1. In Digora and CR panoramic images, compressed images up to ratios of 5 : 1 showed little difference between the original and reconstructed images in subjective assessment of image quality. In CT images, compressed images did up to ratios of 10 : 1 and in MR images up to ratios of 15 : 1. Conclusion : We considered compression ratios up to 5 : 1 in Digora and CR panoramic images, up to 10 : 1 in CT images, up to 15 : 1 in MR images as clinically applicable compression ratios.

형질전환 제초제저항성 벼 밀양 204호의 농업적 특성

정응기,이기환,원용재,박향미,전남수,최준호,구연충,한창덕,은무영,김태산,남민희 Plant molecular biology and biotechnology research 2005 Plant molecular biology and biotechnology research Vol.2005 No.

This study was conducted to investigated the major characteristics of genetically modified rice of "Milyang 204" originated from Dongjinbyeo compared to a non-transgenic rice varieties Dongjinbyeo and Junambyeo. Basta resistant transgenic rice lines carrying bar gene produced by the Yeongnam Agricultural Research Institute were evaluated for their agronomic characters. The transgenic Japonica rice of "Milyang 204" showed inferior phenotypic traits compared to a non-transgenic rice variety Dongjinbyeo and Junambyeo. On the basis of UPOV (Union Internationale Pour la Protaection des Obtentions Vegetables) and NSMO(National Seed Management Office) the transgenic "Milyang 204" showed difference in some traits out of some agronomic traits, such as leaf color, angle of flag leaf, number of spikelets, culm length, white core and white belly compared to the nontransgenic varieties rice.

전경대원에서 발생한 결핵의 임상 양상

문창기,박상준,조민구,김영중,김소연,김윤권,정준오,안석진,김은실,서승오,김지훈,최원제,이윤영,박형기,최규영,김현근 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

Background: The purpose of this study was to document the incidence and clinical characteristics of patients with tuberculosis (TB) in combat and auxiliary police, living in a group, in Korea where the incidence rate of active TB in a general population is higher than in Western countries. Materials and Methods:We retrospectively reviewed the medical records of all tuberculosis patients diagnosed at National Police Hospital from January 2002 through December 2004. Results:In 2002-2004, a total of 156 cases of tuberculosis were identified with the mean (Standard deviation) age of 20.6 (±1.0) years. Of these, 134 (85.9%) patients were registered as new cases, 11 (7.1%) as relapse, 2 (1.3%) as failure, 5 (3.1%) as treatment-after-default cases whereas 4 (2.6 %) patients were not included in any categories. Average annual new TB rate and smear-positive TB rate were 86.5/10^(5) and 17.4/10^(5) person-years, respectively. In 12 of 31 smear-positive cases, time from onset of symptoms to diagnosis was more than 30 days. Two multidrug-resistance TB cases were identified and two suspected outbreak episodes of TB had occurred during 3 years. Conclusion:There was no statistically significant difference in the incidence rate of new cases of TB between the general population aged 20 to 29 years and combat and auxiliary police in Korea. 배경 : 국내 결핵의 발생은 감소 추세에 있으나 여전히 후진국형 발생양상을 보이고 있다. 특히 집단생활을 하는 젊은이들에서 발생하는 결핵의 유행이 간헐적으로 알려지고 있어 우려를 낳고 있다. 이에 저자들은 최근 전경대원의 결핵 발병 양상에 대해 알아보고자 본 연구를 시행하였다. 재료 및 방법 : 2002년 1월부터 2004년 12월까지 3년간 경찰병원에서 결핵 진료를 받은 전경대원의 의무기록을 후향적으로 분석하여 연도별 결핵 신환발생률, 도말양성결핵 신환율, 진단 지연, 집단발병, 다제내성결핵을 조사하였다. 결과 : 연도별 결핵 신환자 수(10만명당 발생추정치)는 2002년 50명(83.6명), 2003년 42명(83.7명), 2004년 42명(93.5명)이었고 도말양성 폐결핵 신환자 수는 2002년 10명(16.7명), 2003년 11명(21.9명), 2004년 6명(13.4명)이었다. 3년간 도말양성 폐결핵 환자는 31명이 있었고 그 중 12명은 호흡기 증상 발생 30일이 지나서 진단을 받았다. 다제내성 결핵은 2명이 있었으며 결핵의 집단발병이 의심되는 사례는 2차례 있었다. 결론 : 전경대원과 20-29세 연령군 일반인의 결핵 신환발생률, 도말양성 폐결핵 발생률의 통계적으로 유의한 차이는 없었다.

실시간 시스팀 설계를 위한 큐잉모텔 적용 분석에 관한 연구

柳基漢,崔英奎,元忠常 忠州大學校 1993 한국교통대학교 논문집 Vol.28 No.-

This paper presents the analysis of queueing model to be applied to the development of real-time system on the base of the computer To analyze the perfarmance of queue, we selected the queueing model, M/M/1 (N) which is employed in general and got the analysis result through simulation. This result becomes the important element when developing a real-time system with message queues.

제주도 지하수의 전기비전도도와 염소이온의 지역별 변화 양상

고기원,문영석,최영찬,고용구 제주대학교 해양연구소 1995 해양자원연구소연구보고 Vol.19 No.-

양지면 전원주택단지 프로젝트 계획

김신원,정유홍,노희곤,도의성,최기왕 경희대학교 디자인연구원 2006 예술· 디자인학연구 Vol.9 No.2

This plan of rural housing-development is to present a new orientation for the residential culture that can meet the shifting demands of modern people as their attitudes toward naturalistic life. In this plan, sites of possible, a new housing complex is designed to supplement the site partition problem of existing housing complex by using attractiveness that the site has as a residence environment in housing planning. The conclusion can be summarized as follows. 1. Currently, most residential developments on slopes are planned with excessive slope cutting or filling on existing natural slopes rather than utilizing existing contours. In consideration of this, this proposed plan uses the existing contours of the slope to the maximum capacity in site planning. 2. The majority of the home site buyers are between the ages 30's to 50's of middle to high level incomes. Reflecting the financial needs of these families, home construction was planned by using building methods that require lower costs. 3. Reflected open-space furtherance maximum at design of community equipment for party's offer to sale in lots persons, from site purchase recognition of construction to in package sale in lots way select. 4. Considered to preserve existing natural-food life in way financial world stroke maximum, and accomplish creation with existing vegetation. Also, did planting considering privacy, and considered vegetation's environment adaptation degree because using midland style vegetation. 5. Garden wished to offer an opportunity that can make by oneself directly depending on each fondness and character to tenants. If is this intuition, wished to design, and maintained spur of housing development because housing development uses maximum natural history style comparing with other power jars all. Also, because considering people who move in housing-development, designed, and tried to make housing-development that want to live most offering the convenience.