Distribution of the Fairy Pitta (Pitta nympha) in the South Korea: A focus on protected areas

Gil-Pyo Hong(홍길표),Jae-Hoon Kim(김재훈),Seul-Gi Seo(서슬기),So-Yeon Cho(조소연),Bo-Yeon Hwang(황보연),Jong-Hyun Park(박종현),Seung-Yeon Lee(이승연),Ga-Young Kim(김가영),Wan-Hee Nam(남완희),Ha-Cheol Sung(성하철) 한국조류학회 2021 한국조류학회지 Vol.28 No.2

국내 팔색조(Pitta nympha) 분포 현황을 알아보고자 전국 국립공원 등 보호지역 중심으로 총 19개 지역을 조사하였고, 전문가 네트워크를 통해 자료를 보강하였다. 전국 19개 지역을 조사한 결과 북한산, 지리산 등 내륙지역 7개 국립공원에서는 팔색조가 확인되지 않았고, 경남 거제, 남해, 해남, 장흥 고흥 등 남해안과 인접한 12개 지역에서 팔색조 서식이 확인되었다. 또한 전문가 네트워크를 통해 수집한 팔색조 출현 위치 정보 82건을 분석한 결과, 전국 8개 광역지자체 모두 팔색조 서식이 확인되었고, 내륙지역(26.8%)보다 해안지역(73.2%)에서 더 많이 출현하였다. 연구 결과를 종합해보면, 우리나라의 팔색조는 주로 제주도와 남해안 지역을 중심으로 많이 분포하며, 그 보다 적은 개체수가 내륙 지역에 넓게 분포하고 있는 것으로 나타났다. The present study investigated the current distribution of Fairy Pitta (Pitta nympha) in South Korea. A total of 19 study areas, including protected areas such as national and provincial parks in South Korea were surveyed, and additional data obtained from an expert network. According to the results, Fairy Pitta was absent in seven inland national parks, including Mt. Bukhan and Chiri parks. Fairy Pitta inhabited 12 areas near the southern coast of South Korea, including Geoje, Namhae, Haenam, Jangheung, Goheung, and Gyeongnam Province. The analysis results of 82 datasets obtained from experts with regard to the locations where Fairy Pitta have been spotted showed that the bird inhabits all the eight metropolitan regions in South Korea, and is more frequently spotted in coastal areas (73.2%) than in inland areas (26.8%). The findings demonstrate that Fairy Pitta is mainly distributed in Jeju Island and the southern coast of South Korea, and is distributed in inland areas at relatively lower numbers.

수면량과 집중력의 상관관계

김병우,류지근,박우진,박계원,김미정,임지은,백대현,최재덕,최윤호,이가현,이관,김덕수 東國大學校醫學硏究所 2002 東國醫學 Vol.9 No.1

수면, 기억 그리고 학습의 연관성은 실제 매우 복잡하다. 많은 연구에도 불구하고 명확한 연구결과는 아직 없다. 우리는 이 연구에서 평소와는 달리 시험 전날 수면 변화 양상이 집중력에 어느 정도 영향력을 미치는지 알아보고자 하였고, 이를 이용해 효율적인 수면 관리를 할 수 있는 기초자료로 삼고자 하였다. 동국대 의대 본과 1학년생 중 지원자 30명과 본과 2학년생 10명을 대상으로 평상시 상태와 시험 직후 수면이 부족한 상태에서 각각 K-PES TEST를 실시하여 총 8항목에 걸쳐 암기력, 판단력, 단순반응의 변화정도를 검사하였다. 또 설문조사를 병행하여 결과에 영향을 미칠 수 있는 다른 인자들도 파악하였다. 수면량에 대한 부호 숫자 짝짓기(순간 판단력)을 검사한 결과, 인간의 최대 생리학적 기능은 꼭 수면부족에 의해 좌우되는 것은 아니다. 그러나, 수면감소는 피로를 증가시키고, 동기부여를 감소시키나 단, 새로운 사실을 학습하는 데에는 큰 영향을 끼치지 않는다. 즉, 수면부족으로 장시간 깨어있는 것은 정확성과 반응성을 떨어뜨린다. 흡연에 대한 부호 숫자 짝짓기(순간 판단력)을 검사한 결과, 니코틴의 수면에 대한 상호관계는 알려지지 않았고, 인간의 감정이나 의식, 인식에 영향을 주는 것으로 알고있지만, 장기적은 측면에서 흡연이나 알코올은 인식능력과 무관한 것 같다. 카페인에 대한 숫자 외우기(암기력)검사 결과, 카페인은 spacial selective attention에는 특별한 영향을 주지 않지만 지각과정이나 주의 집중에 큰 효과를 주며, 인간의 의식 수행에 긍정적인 효과를 준다. 즉 카페인은 활력, 혼란, 피로상태를 변화시키고 visual analog scales에서 휴식상태에 가까운 양상을 나타낸다. 또 48시간 동안 수면을 취하지 않은 사람에게 카페인은 집중력과 장시간의 좋은 기분을 유지하게 하였다. 그러나 규칙적, 비규칙적으로 먹는 사람간에는 인지수행력의 차이를 보이지 않으며 상용자에서는 상당한 내성이 보인다. 수면패턴에 대한 숫자 더하기(순간 판단력)검사 결과, 집중력은 수면패턴에 의해서도 영향을 받고, 수면패턴이 바뀌게 되면 순간판단력을 저하시킨다. This study was performed to evaluate relationship of sleep and attention, and to control sleep effectively. We conducted a K-PES test of 40 medical students. K-PES contains eight elements, for example, simple response, selective response, color pairing, OddEven discrimination, number addition, number-symbol matching, memory, right-tapping, left tapping. Through these, we tested changes of memory, judgement, simple response. And we conducted a questionnaire survey to exclude bias. Results are as follows. As a results of number-symbol matching test, we know that sleeplessness is not complete responsible for physiologic function for humans. But, decreased sleep increases fatigue and decreases motivation, but no influence on learning new materials. So, long term sleeplessness decreases precision and responsibility. As a results of number-symbol matching test on smoking, a relationship of nicotine and sleep is not certain. A point of view in long term period, smoking and drinking is not related cognition, even if we know that those influence mood, consciousness and cognition. As a results of memory work test on caffeine, caffeine does not influence spacial selective attention, but mainly does perception, attention and consiousness process. Namely caffeine changes energetic activities, chaos, fatigue states and shows resting state in visual analog scales In sleeplessness for 48 hours, caffeine produced attention and good mood for a long time. But, in case of cognitive process no significance shows in regular or irregular diet. Regular diet shows high resistance. As a results of number addition test on sleep patterns, seep patterns influence attention, changes of sleep patterns decrease a moment judgement.

洛東江 河口周邊의 防災對策에 관한 基礎的인 硏究

민일규,김원규,최병습,박상길,김가현 釜山大學校生産技術硏究所 1996 生産技術硏究所論文集 Vol.51 No.-

波浪과 흐름이 共存하는 大河川 河口部인 洛東江 河口域에서 洛東江 河口둑을 基点으로 波浪, 흐름, 地形變動, 潮流, 洪水位等을 評價基準으로 하여 災害에 대한 基本的인 評價를 實施했다. 波浪, 潮流, 洪水位等이 水位上昇을 透發시켜 周邊地域을 浸水시킬 수 있는 危險性의 與否를 實測과 數値計算을 통하여 實施하였다. 地形變動은 實測만을 통하여 地形變動率을 調査하였다. 資料를 分析한 結果 洛東江 河口地域은 波浪, 흐름과 波浪이 共存하는 領域으로 區分된다. 數値計算結果에 의하면 河口部에서의 來襲波高가 直接 河口둑 水門과 주변構造物에 미치는 影響은 크지 않았다. 또한, 3次元 波高分布를 볼 때 河口 水路를 따라서 거슬러 올라오는 波浪의 影響은 거의 없었다. 洪水位와 流速은 災害를 透發시키는 主要因子로 評價되었다. 波浪에 의한 異常高潮와 漲潮流와 潮汐의 滿潮時間 및 最大洪水量이 時間적으로 一致되는 境遇, 河口둑 周邊地域의 水位 上昇과 流速의 停滯現狀으로 浸水狀態가 發生한다. For the investigation of inundation disasters by wave setup in the Nakdong Estuary of the Large River which waves and currents are coexist, the wave surveying data was analyzed and the numerical model was applied to the Estuary. In this study, the result of surveying data analysis shows that waves have little effect on the surroundings. As the result of numerical computation, waves have seldom direct influence upon the barrage and its gates. Also, according to three dimension distribution of waves, it is found that coming up waves along the Estuary channel and the setup of waves have seldom effect barrage structures.

Surgical Outcomes of Sphenoid Wing Meningioma with Periorbital Invasion

Park, Ga-On,Park, Hyun Ho,Yoo, Jihwan,Hong, Chang-Ki,Oh, Jiwoong The Korean Neurosurgical Society 2022 Journal of Korean neurosurgical society Vol.65 No.3

Objective : The aim of this study was to evaluate the clinical outcome of sphenoid wing meningioma with periorbital invasion (PI) after operation. Methods : Sixty one patients with sphenoid wing meningioma were enrolled in this study. Their clinical conditions were monitored after the operation and followed up more than 5 years at the outpatient clinic of a single institution. Clinical and radiologic information of the patients were all recorded including the following parameters : presence of PI, presence of peri-tumor structure invasion, pathologic grade, extents of resection, presence of hyperostosis, exophthalmos index (EI), and surgical complications. We compared the above clinical parameters of the patients with sphenoid wing meningioma in the presence or absence of PI (non-PI), then linked the analyzed data with the clinical outcome of the patients. Results : Of 61 cases, there were 14 PI and 47 non-PI patients. PI group showed a significantly higher score of EI (1.37±0.24 vs. 1.00±0.01, p<0.001), more frequent presence of hyperostosis (85.7% vs. 14.3%, p<0.001), and lower rate of gross total resection (GTR) (35.7% vs. 68.1%, p=0.032). The lower score of pre-operative EI, the absence of both PI and hyperostosis, smaller tumor size, and the performance of GTR were associated with lower recurrence rates in the univariate analysis. However, in the multivariate analysis, the performance of GTR was the only significant factor to determine the recurrence rate (p=0.043). The incidences of surgical complications were not statistically different between the subtotal resection (STR) and GTR groups, but it was strongly associated tumor size (p=0.017). Conclusion : The GTR group showed lower recurrence rate than the STR group without differences in the surgical complications. Therefore, the GTR is strongly recommended to treat sphenoid wing meningioma with PI for the better clinical outcome.

Precise control of mitophagy through ubiquitin proteasome system and deubiquitin proteases and their dysfunction in Parkinson’s disease

Ga Hyun Park,Joon Hyung Park,정광철 생화학분자생물학회 2021 BMB Reports Vol.54 No.12

Parkinson’s disease (PD) is one of the most common neurodegenerativediseases in the elderly population and is caused bythe loss of dopaminergic neurons. PD has been predominantlyattributed to mitochondrial dysfunction. The structural alterationof α-synuclein triggers toxic oligomer formation in the neurons,which greatly contributes to PD. In this article, we discuss therole of several familial PD-related proteins, such as α-synuclein,DJ-1, LRRK2, PINK1, and parkin in mitophagy, which entails aselective degradation of mitochondria via autophagy. Defectivechanges in mitochondrial dynamics and their biochemical andfunctional interaction induce the formation of toxic α-synucleincontainingprotein aggregates in PD. In addition, these gene productsplay an essential role in ubiquitin proteasome system(UPS)-mediated proteolysis as well as mitophagy. Interestingly,a few deubiquitinating enzymes (DUBs) additionally modulatethese two pathways negatively or positively. Based on thesefindings, we summarize the close relationship between severalDUBs and the precise modulation of mitophagy. For example,the USP8, USP10, and USP15, among many DUBs are reportedto specifically regulate the K48- or K63-linked de-ubiquitinationreactions of several target proteins associated with the mitophagicprocess, in turn upregulating the mitophagy and protectingneuronal cells from α-synuclein-derived toxicity. In contrast,USP30 inhibits mitophagy by opposing parkin-mediated ubiquitinationof target proteins. Furthermore, the association betweenthese changes and PD pathogenesis will be discussed. Takentogether, although the functional roles of several PD-relatedgenes have yet to be fully understood, they are substantiallyassociated with mitochondrial quality control as well as UPS. Therefore, a better understanding of their relationship providesvaluable therapeutic clues for appropriate management strategies.

Characteristics of a probiotic strain isolated from Korean traditional fermented food for using fish feed additives

Ga-Hyun Park,Su-Jung Lee,Da-In Noh,Young-Sun Lee,Ji-Yeon Yoon,Tae-Rim Kim,Eun-Woo Lee 한국수산과학회 양식분과 2022 한국수산과학회 양식분과 학술대회 Vol.2022 No.10

Annular elastolytic giant cell granuloma initially misdiagnosed as granuloma annulare

( Ga Ram Ahn ),( Hyun Jung Kwon ),( Kui Young Park ),( Seong Jun Seo ),( Chang Kwun Hong ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1

Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous dermatosis which is characterized by annular atrophic lesions which tend to occur in sun-exposed area. Due to its annular morphology and histopathologic feature which include a granulomatous infiltration with multinucleated giant cells, AEGCG is often difficult to be distinguished from granuloma annulare (GA). A 49-year-old woman was referred to our clinic presenting multiple annular lesions on her forehead, upper chest and both forearms and hand dorsa. With the initial impression of GA, she was treated with systemic steroid and UV-A therapy. Since the lesions progressed gradually in spite of the treatment, skin biopsy was performed. The biopsy specimen showed granulomatous hystiocytic infiltration with multinucleated giant cells engulfing fragmented elastin fibers. Herein, we report a case of AEGCG which was initially misdiagnosed as GA and discuss the clinical and histopathological differential diagnosis through review of literatures.

Moisture Wound Healing Characteristics of Alginate Sponge and Hydrogel

Ga Young Park(박가영),Jeong Hyun Yeum(염정현),Dong Joon Yang(양동준),Guen Oh Park(박근오),Yun Hee Kim(김윤희),Saewha Jeon(전세화),Tae Jung Kim(김태정),Eun Jung Oh(오은정),Ho Yun Chung(정호윤),Jin Hyun Choi(최진현) 한국고분자학회 2018 폴리머 Vol.42 No.1

건조/가교법으로 제조한 알지네이트 스폰지 및 하이드로젤의 물리적, 생물학적 특성 및 창상치유 특성을 고찰하였다. 하이드로젤은 스폰지 대비 높은 평형 함수율을 보유하였고, 자체적으로 수분을 함유하고 있기 때문에 상대적으로 우수한 습윤 창상치유 환경을 제공할 수 있었다. 알지네이트 스폰지 및 하이드로젤의 사이토카인 결속효과에 기인하여 대식세포로부터 분비되는 전염증성 사이토카인의 함량이 감소됨을 확인하였으며, 특히 하이드로젤의 사이토카인 억제효과가 더욱 두드러지게 나타났는데, 이는 보다 팽윤된 상태에서 알지네이트 분자의 사이토카인에 대한 결속력이 증가함을 의미한다. 창상형성 초기 하이드로젤에 의한 창상치유 및 수축 효과가 스폰지에 비해 우수한 것으로 나타났으나, 상피화는 스폰지를 적용했을 때 보다 우세하게 진행되었다. 조직학적 평가와 RNA 발현 분석으로부터 알지네이트 스폰지 및 하이드로젤은 혈관 및 콜라겐 섬유의 형성, 상피조직의 재생 및 단백질의 생성 등을 촉진함을 확인하였다. Alginate sponge and hydrogel were prepared by a drying/crosslinking method and their wound healing characteristics were investigated comparatively. The alginate hydrogel had a higher equilibrium water content than the sponge, providing a moist wound healing condition without absorbing exudate from a wound. The amounts of proinflammatory cytokines released by macrophages were lowered due to the cytokine-binding effects of the alginate sponge and hydrogel. The hydrogel lowered the cytokine level more dominantly than the sponge, suggesting that the affinity of alginate molecules to cytokines increases at a more swollen state. The hydrogel allowed superior wound healing and contraction at the early stage of application. However, epithelialization was conspicuous when the sponge was applied. It was confirmed through histological examination and RNA expression analysis that angiogenesis, formation of collagen fibers, regeneration of epithelium, and production of protein were promoted using the alginate sponge and hydrogel as wound dressing materials.

Specific bacteriophage of Bordetella bronchiseptica regulates B. bronchiseptica-induced microRNA expression profiles to decrease inflammation in swine nasal turbinate cells

Ga Young Park,Hyun Jin Yu,Jee Soo Son,Sang Joon Park,Hee‑Jae Cha,Kyoung Seob Song 한국유전학회 2020 Genes & Genomics Vol.42 No.4

Background Respiratory diseases in pigs are the main health concerns for swine producers. Similar to the diseases in human and other animals, respiratory diseases are primary related to morbidity and are the result of infection with bacteria, viruses, or both. B. bronchiseptica causes serious respiratory diseases in the swine airway track. However, the B. bronchisepticaspecific bacteriophage has diverse advantages such as decreasing antibiotic overuse and possible therapeutic potential against bacteria. Objective The objects of this study were to investigate the therapeutic effect of specific B. bronchiseptica bacteriophages and to identify genes related to bacteriophage signaling utilizing RNA microarrays in swine nasal turbinate cells. Methods Bor-BRP-1 phages were applied 24 h prior to B.bronchiseptica infection (1 × 107 cfu/ml) at several concentrations of bacterial infection. Cells were incubated to detect cytokines and 24 h to detect mucin production. And real-time quantitative PCR was performed to examine related genes expression. To determine the change of total gene expression based on B.bronchiseptica and Bor-BRP-1 treatment, we performed RNA sequencing experiments. Results The results showed that B. bronchiseptica induced increased expression of several inflammatory genes such as IL-1β, IL-6, and Muc1 in a dose-dependent manner. However, Bor-BRP-1 induced reduction of gene expression compared to the B. bronchiseptica induction group. In addition, microarrays detected Bor-BRP-1-altered inflammatory gene expression against B. bronchiseptica, reducing B. bronchiseptica-induced airway inflammation in swine epithelial cells. Conclusion These results suggest that the specific bacteriophage has a therapeutic potential to defend against B. bronchiseptica infection by altering inflammatory gene expression profiles.

Complication Profiles Associated with Sacral Alar Iliac Screw Fixation in Patients with Adult Spinal Deformity: A Comparative Analysis to the Conventional Iliac Screw Fixation

Park Ga-On,Choi Un-Yong,Kim Kyung Hyun,Park Jeong Yoon,Chin Dong Kyu,Kim Keun Su,Cho Yong Eun 대한말초신경학회 2021 The Nerve Vol.7 No.2

Objective: This study aimed to compare the radiographic and clinical outcomes between sacral alar iliac (SAI) screw fixation and conventional iliac (CI) screw fixation with a particular focus on the rate of reoperation, surgical site infection (SSI), sacroiliac joint pain, instrument failure, and screw prominence.Methods: Patients who underwent sacropelvic fixation in the authors’ institution from June 2011 to May 2017 were retrospectively investigated. Forty-three patients with SAI screw fixation and 25 with CI screw fixation were included. Preoperative patient and surgical characteristics and postoperative outcomes and complications were analyzed between the SAI and CI groups. Radiographic parameters were analyzed before and after surgery.Results: Lumbosacral fusion rates showed no statistically significant difference between the SAI group and CI groups (90.7% vs. 92.0%, p=0.878). The SAI group showed a significantly good result with regard to SSI compared to the CI group (0% vs. 16%, p=0.016), but had a significantly higher rate of distal screw fracture than the CI group (16.3% vs. 0%, p=0.042).Conclusion: The SAI screw fixation technique could achieve good outcomes of pain relief, deformity correction, and lumbosacral fusion rate with relatively lower complications such as the rates of reoperation, SSI, and screw prominence as compared to the CI screw fixation technique. However, distal instrument failure was observed more frequently in the SAI group, requiring further biomechanical studies.