http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Management of Irq-Un-Nasa (Sciatica) by Fasd (Venesection): A Case Report
Khan, Fatima,Nayab, Mohd,Ansari, Abdul Nasir Cellmed Orthocellular Medicine and Pharmaceutical 2022 셀메드 (CellMed) Vol.12 No.2
Objectives: Sciatica is a musculoskeletal pain sensed in the leg along with the distribution of the sciatic nerve, which is sometimes accompanied by low back pain and is most commonly caused by a disc herniation. In the Unani system of Medicine, Irq-un-Nasa (Sciatica) is defined as the pain which starts from the hip joint and descends towards the foot. It is a type of Waja-ul-Mafasil which is developed due to the accumulation of Khilt-e-Dam or Khilt-e-Balgham ghaleez in the hip joint. The conventional system of Medicine offers several medications and surgeries to manage sciatica with limited clinical evidence of effectiveness. These cases aim to provide insight into the effects of Fasd (Venesection) in Irq-un-Nasa. Case Presentation: Fasd was performed in the saphena minor vein of two clinically diagnosed patients with sciatica after the initial assessment. Two sittings of Fasd, once a week in each patient, were performed, followed by telephonic assessments for two months. The intensity of sciatic pain reduced with subsequent sittings of Fasd, and there was no recurrence of any symptoms and signs again during complete follow-up. Conclusion: Based on the results of the present case report, it appears that such cases of Irq-un-Nasa can be managed with Fasd, and the quality of life of such patients can also be improved.
Fatima, Suhail,Siddiqui, Aisha,Khan, Afshan Cellmed Orthocellular Medicine and Pharmaceutical 2019 셀메드 (CellMed) Vol.9 No.4
The medicinal plants are extensively used for curing variegated malady in day to day life. There is an emergent demand for plant based medicines, food supplements, health products, pharmaceuticals etc. Mochrus (Bombax ceiba Linn.) is one of the valuable medicinal plants used in Unani system of medicine since relic belongs to family Bombacaceae. It is a tall tree and widely distributed through India, Africa, Australia and tropical Asia. Many parts of the plant (root, stem bark, gum, leaf, prickles, flower, fruit, seed and heartwood) are used for the treatment of a variety of ailments. It is reported to possess nafe sailanur reham (beneficial in leucorrhea), mujaffif (siccative), muqawwi reham (uterine tonic), qabiz (constipative), muallide mani (production of semen), mumsik wa mughalliz mani (increase consistency of semen), dafe fasaad khoon wa safra (purifies blood and bile) etc. It is used in asthma, diarrhoea, wound, leprosy, boils and many other skin diseases. Also possess some important pharmacological activities such as antioxidant, analgesic, antipyretic, antibacterial, diuretic, hepatoprotective, anticancer, hypoglycaemic and hypotensive etc. It is reported to contain phytoconstituents like polysaccharides, naphthoquinones, anthocyanins, lupeol and naphthol etc. This paper provides a compendium review on pharmacological, phytochemical properties and therapeutic benefits of the plant.
Potential of Bacillus velezensis as a probiotic in animal feed: a review
Fatima Khalid,Anam Khalid,Yuechi Fu,Qian Hu,Yunfang Zheng,Salman Khan,Zaigui Wang 한국미생물학회 2021 The journal of microbiology Vol.59 No.7
Bacillus velezensis is a plant growth-promoting bacterium thatcan also inhibit plant pathogens. However, based on its properties,it is emerging as a probiotic in animal feed. This reviewfocuses on the potential characteristics of B. velezensisfor use as a probiotic in the animal feed industry. The reviewwas conducted by collecting recently published articles frompeer-reviewed journals. Google Scholar and PubMed wereused as search engines to access published literature. Basedon the information obtained, the data were divided into threegroups to discuss the (i) probiotic characteristics of B. velezensis,(ii) probiotic potential for fish, and (iii) the future potentialof this species to be developed as a probiotic for theanimal feed industry. Different strains of B. velezensis isolatedfrom different sources were found to have the ability toproduce antimicrobial compounds and have a beneficial effecton the gut microbiota, with the potential to be a candidateprobiotic in the animal feed industry. This review providesvaluable information about the characteristics of B. velezensis,which can provide researchers with a better understandingof the use of this species in the animal feed industry.
Fatima, Nosheen,Zaman, Maseeh Uz,Maqbool, Aamir,Khan, Shaista H.,Riaz, Nazia Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.1
Background: The aim of this epidemiological study was to establish the laterality of breast cancer (BC) and its association with size, receptor status of the primary tumor and bone metastasis (BM) in a local population. Materials and Methods: This retrospective study included cases of BC from Jan-2009 to Dec-2011 who were referred for metastatic work up or follow up survey with Technetium-99m MDP bone scan (BS) to the Nuclear Medicine Department of Karachi Institute of Radiotherapy and Nuclear Medicine (KIRAN). A total of 384 patients out of 521 were included and all reviewed for age, primary tumor size (PTS), laterality, receptor status like estrogen receptor (ER) progesterone receptor (PR) and Her-2-Neu receptor, presence or absence of BM with sites of involvement and time interval between diagnosis of BC and appearance of BM. Results: The left to right sided BC proportion was significantly higher than unity (59%:41%; p<0.001). The right sided BC was observed in younger age group (46:52 years; p<0.0001) and with a smaller PTS than the left sided (3.43:4.15 cm; p<0.0001). The patients with BM had relatively higher negative receptor status with a significant predominance of right sided BC. The overall incidence of BM on BS was 28% and relatively higher in right than left breast (33%:24% p=0.068). The average number of BM sites was also significantly greater for the right side (6:4, P<0.0001). The % cumulative risk of BM in right breast was noted at significantly smaller PTS than left side with log rank value of 5.579; p<0.05. The Kaplan Meier survival plot for event free survival of BM in left sided BC was significantly higher than for the right side (log rank value=4.155, p<0.05), with an earlier appearance of BM in right BC. Conclusions: 1) A left sided predominance of BC was seen in local population; 2) right sided BC had a more aggressive behavior with extensive and earlier appearance of BM at relatively younger age, smaller PTS and receptor (s) negativity.
Khan, M.Zaheer,Zaheer, Maria,Fatima, Farina The Korean Society for Integrative Biology 2003 Korean journal of biological sciences Vol.7 No.2
The present studies investigate the induced effects of two pesticides lambda cyhalothrin (pyrethroid) and monocrotophos (organophosphate) on Rana cyanophlyctis (common skittering frog). Two different concentrations i.e. 0.1 and 1% were used and cholinesterase activity was observed in liver, kidney and brain of these frogs. It was decreased upto 34.6 and 46.3% in liver, 25.08 and 57.1% in kidney and 31.64 and 50.7% in brain under the effect of lambda cyhalothrin. In the case of monocrotophos treatment, cholinesterase decreased upto 37.7 and 57.7% in liver,57.5 and 67.5% in kidney and 47.6 and 65.9% in brain, respectively.
HaqueMohammadEnamul,Fatima Khan,Lianhua Chi,Smriti Gurung,Sri Murugan Poongkavithai Vadevoo,박랑운,김동규,김상균,이병헌 대한암학회 2019 Cancer Research and Treatment Vol.51 No.3
Purpose This study was carried out to identify a peptide that selectively binds to kidney injury molecule- 1 (KIM-1) by screening a phage-displayed peptide library and to use the peptide for the detection of KIM-1–overexpressing tumors in vivo. Materials and Methods Biopanning of a phage-displayed peptide library was performed on KIM-1–coated plates. The binding of phage clones, peptides, and a peptide multimer to the KIM-1 protein and KIM-1–overexpressing and KIM-1–low expressing cells was examined by enzyme-linked immunosorbent assay, fluorometry, and flow cytometry. A biotin-peptide multimer was generated using NeutrAvidin. In vivo homing of the peptide to KIM-1–overexpressing and KIM- 1–low expressing tumors in mice was examined by whole-body fluorescence imaging. Results A phage clone displaying the CNWMINKEC peptide showed higher binding affinity to KIM-1 and KIM-1–overexpressing 769-P renal tumor cells compared to other phage clones selected after biopanning. The CNWMINKEC peptide and a NeutrAvidin/biotin-CNWMINKEC multimer selectively bound to KIM-1 over albumin and to KIM-1–overexpressing 769-P cells and A549 lung tumor cells compared to KIM-1–low expressing HEK293 normal cells. Colocalization and competition assays using an anti–KIM-1 antibody demonstrated that the binding of the CNWMINKEC peptide to 769-P cells was specifically mediated by KIM-1. The CNWMINKEC peptide was not cytotoxic to cells and was stable for up to 24 hours in the presence of serum. Whole-body fluorescence imaging demonstrated selective homing of the CNWM-INKEC peptide to KIM-1–overexpressing A498 renal tumor compared to KIM- 1–low expressing HepG2 liver tumor in mice. Conclusion The CNWMINKEC peptide is a promising probe for in vivo imaging and detection of KIM-1– overexpressing tumors.
Association of XRCC1 Gene Polymorphisms with Breast Cancer Susceptibility in Saudi Patients
Al Mutairi, Fatima Masoud,Alanazi, Mohammed,Shalaby, Manal,Alabdulkarim, Huda A.,Pathan, Akbar Ali Khan,Parine, Narasimha Reddy Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.6
Background: X-ray repair cross-complementing group 1 (XRCC1) plays a key role in the base excision repair pathway, as a scaffold protein that brings together proteins of the DNA repair complex. XRCC1 is reported to be a candidate influence on cancer risk. The aim of our present study was to assess the association of rs1799782 (Arg194Trp) and rs25487 (Arg399Gln) XRCC1 gene polymorphisms with breast cancer in the Saudi population. Materials and Methods: The two SNP's were analyzed in breast cancer patients and healthy control subjects. Genotypes were determined by TaqMan SNP genotype analysis technique and data were analyzed using Chi-square or t test and logistic regression analysis by SPSS16.0 software. Results and Conclusions: Results showed that rs1799782 significantly increased susceptibility to breast cancer with Arg/Trp, Arg/Trp+Trp/Trp genotypes and at Trp allele overall study. It also increased risk of breast cancer in older age patients (above 48) and with the ER positive category. XRCC1rs25487 (Arg399Gln) did not showed any significant association. In conclusion the XRCC1rs1799782 polymorphism may be involved in the etiology of breast cancer in the Saudi population. Confirmation of our findings in larger populations of different ethnicities is warranted.