SIRAS (ALBIZIA LEBBECK (L.) BENTH.) AND ITS MEDICINAL USES IN UNANI MEDICINE- A REVIEW

Waseem, Azma,Jamal, Anwar,Ahmad, Waseem,Fazil, Mohammad Cellmed Orthocellular Medicine and Pharmaceutical 2020 셀메드 (CellMed) Vol.10 No.2

Higher incidences of adverse reaction associated with the prolonged use of synthetic drugs has once again increased the faith of humans in the traditional systems of medicine and motivated them to return back towards the clinical proven remedies for the treatment. It is also true that number of modern medications used in the present scenario, were developed from various plants. In Unani System of medicine, numerous herbal drugs are mentioned for medicinal purpose. Siras (Albizia lebbeck (L.) Benth.) is one of them. It is found all over India. Almost all parts of this plant are used for the treatment of ailments such as migraine, conjunctivitis, diarrhea, jaundice, skin problems, asthma etc. Many chemical constituents have been isolated from Albizia lebbeck such as lebbekannin, echinocystic acid, flavonoids, Linoleic acid, saponins etc. This review highlights the medicinal properties and therapeutic uses of Albizia lebbeck and scientific studies conducted on the drug in human and animal models that will provide the further research direction.

A comprehensive review on Tukhme Kunjud (Sesamum indicum Linn.) with special reference to Unani System of Medicine.

Khatoon, Rizwana,Abbasi, Hana,Aslam, Mohammad,Chaudhary, Shahid Shah Cellmed Orthocellular Medicine and Pharmaceutical 2019 셀메드 (CellMed) Vol.9 No.3

Sesame (Sesamum indicum L.) is a rich source of edible oil most commonly it is used as a food product mainly in bakeries and also use as a common source of oil in daily kitchen needs. Due to the presence of some special phytochemicals like proteins, fibers, oil, minerals and antioxidants it is highly used for medicinal and therapeutic purposes. It is a good source of energy and act as an antiaging agent. Its seeds are used as Anti-helmintic, antihypertensive, antimicrobial, cytotoxic and Hepatoprotective but its seed coat which is a byproduct of sesame and a cherished source of fibers is normally use for animal feedstuff. In Unani system of medicine it is used both as drug & diet (dawa wa ghida). In classical Unani literature it is indicated in various disorders like Asthma, Dry Cough, Gastritis (due to any drug, excessive use of alcohol), Dryness of Intestine, Dryness in throat, Renal Stone, Bleeding Piles, Amenorrhea, Retention of urine, Dysuria, Orchitis, Sexual Debility, Anorexia. The present review article, an attempt have been made to compile all the pharmacological and Pharmacognostical characters of Sesamum indicum with special reference to Unani literature.

THE THERAPEUTIC USES AND PHARMACOPEAL ACTION OF JIRJEER (Eruca sativa): A Review

Qaiyyum, Ifra Abdul,Nergis, Afiya Cellmed Orthocellular Medicine and Pharmaceutical 2022 셀메드 (CellMed) Vol.12 No.2

The Unani System of Medicine (USM) is one of the traditional systems of medicine that deals with plants. Plants are large source of medicine. JIRJEER (Eruca sativa) is one of the plant origin drugs, has been used for various therapeutic purposes in USM. It contains Erucic acid (major contain), oleic acid, linoleic acid, saturated Fatty acids, Flavonoids, Phenolics, Glucosinolate, Vitamin C and Carotenoids. These active constituents are responsible for their actions described in Unani classical literature such as Muqqawwi-e-bah (Aphrodisiac), Muwallid-e-mani (Spermatomatogenic), Daf-e-sumoom (Antidote), Kasir-e-riyah (Carminative), Jaali (Cleanser/Detergent), Mudirr-e-bawl (Diuretic) wo Mudirr-e-hayd (Emmenogoggue), Muhammir (Rubefacient), Hazim (Digestive), Mulaiyan (Laxative), Muzliq-e-mani (Lubricant), Muddir-e-shir (Galactopoietic), Mufattih-e-Sudad (Deobstruent), Musakhin (Analgesic), Mulattif (Demulcent), Mufattit-i-hasah (Lithotriptic) and whole plant is considered as aphrodisiac. This is a review paper which discusses morphology, pharmacological action, ethno-medicinal and therapeutic uses of this medicinal plant in perspective of Unani medicine. This review has been done through online searches of databases such as PubMed, Google Scholar, Embase, science direct and hand search for classical textbook available in different libraries. It concluded that JIRJEER (Eruca sativa) is one of the best herbal medicines in treatment of Antiulcer, Antibacterial, Fertility, Hepato-protective, Hyperlipidemic, Antioxidant, Antihypertensive, Anti-inflammatory and Anti-edema, Nephro-protective, Antidiabetic, Antifungal and Anticancer properties.

BRIEF HISTORY OF TRANSLATION IN UNANI MEDICINE WITH MAJOR MILESTONES: A GLIMPSE

Ansari, Shabnam Cellmed Orthocellular Medicine and Pharmaceutical 2019 셀메드 (CellMed) Vol.9 No.3

Unani medicine has been used extensively as preventive and therapeutic healthcare in India. It mostly utilizes herbal drugs for the treatment of various conditions and ailments. It is based upon the humoural and temperament theory of Buqrat (Hippocrates). Unani medicine is one of the oldest traditional system rooted within the Greek, Iranian, Arabic, and Islamic medical knowledge and has developed as a scientific healthcare system. It is highly practiced and popular in certain parts of the world, and the World Heritage Centre, part of the United Nations Educational, Scientific, and Cultural Organization (UNESCO), and the United Nations Foundation list it as an authentic and still-living form of traditional medicine. But in the past, its survival required utmost efforts from different dynasties, scholars and organization around the world. The efforts of promotion, preservation, translation, upgradation and publication of medical knowledge has crucially given new life to Unani medicine in each era. This letter will enlighten the efforts of translations of medical knowledge in Unani medicine from its arising need in the past till present.

Preparedness of Siddha system of medicine in practitioner perspective during a pandemic outbreak with special reference to COVID-19

Rajalakshmi, S.,Samraj, K.,Sathiyarajeswaran, P.,Kanagavalli, K. Cellmed Orthocellular Medicine and Pharmaceutical 2020 셀메드 (CellMed) Vol.10 No.4

COVID-19 (Corona Virus Disease-2019) is an infectious respiratory disease caused by the most recently discovered coronavirus, SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona virus-2). This new viral disease was unknown before the outbreak began in Wuhan, China, in December 2019. As of November 16th 2020, it affects about 54.3 million populations, death troll increased to 1.32 million cases in worldwide. Whereas in India 8.85 cases are infected with COVID-19, of which 1, 30, 112 cases were died. Till now there has been no specific anti-virus drug or vaccines are available for the treatment of this disease, the supportive care and non-specific treatment to the symptoms of the patient are the only options in Biomedicine, the entire world turns its attention towards alternative medicine or Traditional medicine. Siddha medicine is one of the primordial systems of medicine practiced in the southern part of India, it dealt a lot about pandemic, and its management. This review provides an insight into Pandemic in Siddha system and its management in both ancient history and modern history, National and state level Government policies related to current pandemic, World Health Organization (WHO) guidelines on usage of unproven drug during infectious disease outbreak, Preparedness of Siddha system during a pandemic outbreak Challenges and Recommendations.

Photostability evaluation of Jawarishe Jalinoos

Shahnawaz, Shahnawaz,Rahman, Khaleequr,Sultana, Arshiya,Sultana, Shabiya Cellmed Orthocellular Medicine and Pharmaceutical 2021 셀메드 (CellMed) Vol.11 No.4

Jawarishe Jalinoos (JJ) is an orally used formulation available in semisolid dosage form, prepared with powdered plant materials mixed in honey or sugar syrup. It has many admirable pharmacological effects and used in Unani medicine to treat various acute and chronic disorders since ancient times. The ICH Harmonised Tripartite Guideline stated that photostability testing should be an essential part of stability testing to confirm that light exposure does not result in an unacceptable change in drugs substance and finished products. To date, the effect of light on JJ is not studied, in this study photostability evaluation of JJ was carried out. The test sample was manufactured with genuine ingredients in the in-door pharmacy of the National Institute of Unani Medicine. JJ was packed in two transparent polyethylene terephthalate airtight containers. The first sample was analysed at zero-day and the second sample was placed in a stability chamber subjected to light challenge with an overall illumination of 1.2 million lux hours combined with near ultraviolet energy of 200-watt hours per square meter by using option 2, along with 30±2℃ temperature and relative humidity 70±5%. Analysis of both finished products showed no considerable changes in organoleptic characters. Less than 5% variation was observed in physicochemical parameters. HPTLC fingerprinting showed justifiable variation. Microbial load and specific counts were within the limit prescribed by WHO. As no unacceptable changes were noted in JJ subjecting to light challenge, it is concluded that JJ is a photostable Unani compound formulation.

Fasad (Venesection): An important regimental therapy in Unani System of Medicine

Khan, Javed ahmad,Nikhat, Shagufta,Ahmad, Naseem,Zohaib, Sharique,Parray, Shabir ahmad Cellmed Orthocellular Medicine and Pharmaceutical 2017 셀메드 (CellMed) Vol.7 No.4

Fasad i.e. venesection is an old classical method of treatment in the Unani system of medicine. Fasad is Arabic word which means "to open". In the process, complete evacuation which drains out blood and dominating humours mixed with blood from veins. Fasad is carried out when the kamiyat (quantity) of the blood is excess in the body and patient is either exposed to the risk of developing a disease or has actually developed one. In classical literature of Unani system of medicine, physicians wrote a lot about this procedure. The details of venesection is mentioned in the given paper on the basis of classical literature including history, indications, types, amount of blood to be venesected, time, person, procedure, complications and special focus has been made on the number of vessels to be venesected and their benefits with respected to disease and condition.

Therapeutic Effects of Botanicals Used in Management of Dhiq al-Nafas (Bronchial Asthma): An Evidence Based Review

Ahmad, Taufiq,Parray, Shabir Ahmad,Ahmad, Naseem,Khan, Javed Ahmad,Zohaib, Sharique Cellmed Orthocellular Medicine and Pharmaceutical 2019 셀메드 (CellMed) Vol.9 No.1

Bronchial asthma is one of the most common chronic diseases globally and currently affects approximately 300 million people worldwide. As per scientific data, approximately 10-12% of adults; and 15% of children are affected by the disease. The increasing global prevalence of the disease imposes a high health care costs into its mechanisms and treatment. Unani system of medicine (USM) is a well known traditional therapy for number of diseases since ancient times. Time has proved that USM has a special role in treatment of chronic diseases, due its special Usooleillaj (Line of treatment). Dhiq al-Nafas (bronchial asthma) is also considered as a chronic disease. Since ancient times, the disease was cured by number of single as well as compound formulations by renowned Unani scholars. This review provides a comprehensive summary of medicinal plant throughout the world, with reference to renowned Unani scholars and physicians for treatment of Dhiq al-Nafas. A number of Unani single and compound drugs, highly efficacious and safe drugs are available for the asthma. The data were taken from classical literature of USM, Modern reference books & electronic journals. The recent information was collected from different authentic search engines. This review will provide the centuries therapeutic information's of classical literature and recent scientific studies of 12 herbal drugs mentioned in USM, which will help the academia, clinicians, research scholars and post graduate students from Unani Medicine, Traditional & Complementary Medicine and other related disciplines, having research interest or work in the Unani medicine.

FICUS CARICA L.: A PANACEA OF NUTRITIONAL AND MEDICINAL BENEFITS

Salma, Salma,Shamsi, Yasmeen,Ansari, Saba,Nikhat, Sadia Cellmed Orthocellular Medicine and Pharmaceutical 2020 셀메드 (CellMed) Vol.10 No.1

Since times immemorial, people have been dependant on plants for the various nutritional and pharamacological properties. Folk and traditional medicine recognizes thousands of plant species having miraculous benefits. Fig (Ficus carica Linn.) has been part of folk-lore since centuries. Ficus carica Linn. (Moraceae) is a huge deciduous tree, with more than 800 species. Different parts of Ficus carica like bark, root, leaves, fruit and latex have their own valuable importance and are frequently used for the treatment of various illnesses. Fruit of Ficus carica is commonly called as fig (anjeer) has various medicinal properties used in Unani, Ayurvedic and Chinese traditional system of medicines. Fig fruit is mostly used in gastro intestinal and respiratory disorders. In Unani medicine, fig is used as a diuretic, mild laxative and expectorant. Phytochemical studies on the leaves and fruits of the plant have shown that they are rich in Phenolics, Flavonoids, Vitamin C, Alkaloids, Saponins, Coumarins, tannins, organic acids, and volatile compounds due to which it is having great antioxidant property. Most interesting therapeutic effects include hypoglycemic, hepatoprotective, anticancer, antimicrobial and hypolipidemic activities.

Management of Psoriasis through Unani Medicine: a Case Study

Khatoon, Faiza,Uddin, Qamar,Jabeen, Arzeena,Azahar, Mohd,Alam, Md Aftab,Munim, Abdul Cellmed Orthocellular Medicine and Pharmaceutical 2021 셀메드 (CellMed) Vol.11 No.2

Psoriasis is a chronic inflammatory skin disease clinically characterized by erythematous, sharply demarcated papules and rounded plaques covered by silvery white micaceous scales. It affects about 1-3% of the world's population. Although considerable advances have been made in the management of psoriasis in recent years, the disease remains incurable. Current treatment does not affect disease activity, and relapse occurs quickly after cessation of treatment. Moreover, topical and systemic conventional therapies used in the management of psoriasis are associated with adverse effects. In Unani system of medicine, psoriasis is known as Taqashshur al-Jild, which is caused by predominance of black bile and characterised by scaling of skin. Various topical as well as systemic Unani formulations are effectively used in the management of psoriasis. This case study was aimed to evaluate the efficacy of Unani formulations, Itrīfal Shāhtra and Marham Ḥinā in the management of psoriasis. A 49-year-old male patient presenting with psoriasis came to the OPD of National Research Institute of Unani Medicine for Skin Disorders, Hyderabad. Treatment was given to the patient for a period of 12 weeks. PASI score was significantly reduced from 40.5 at baseline to 2.2 after treatment. Unani formulations were found safe and effective in the management of Psoriasis as assessed by validated scales.