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Caiyun Li,Jixia Li,Yaxian Shang,Yao Wang,Jingru Gao,Nan Xue,Chunying Huang,Farong Li,Jia Li 한국식품영양과학회 2021 Journal of medicinal food Vol.24 No.7
Polygonatum sibiricum (PS) has been used as herbal medicine to treat type 2 diabetes mellitus (T2DM). However, how lactic acid fermentation of PS influences glucose and lipid metabolism remains unclear. The current study was undertaken to evaluate the hypoglycemic and hypolipidemic effects of PS fermented with Lactobacillus brevis YM 1301 (YM 1301) in streptozotocin and high-fat diet-induced T2DM mice. Biochemical analysis revealed that supplementation with metformin, PS, or fermented Polygonatum sibiricum (FPS) lowered the fasting blood glucose, insulin, total cholesterol, triglyceride, and low-density lipoprotein cholesterol of diabetic mice. FPS showed relatively more potency to reduce the homeostasis model assessment-insulin resistance and glycated hemoglobin than PS. Moreover, a high dosage of FPS protected against glucose intolerance and insulin resistance by increasing the ratio of phosphor-AKT/AKT. Histological examination and quantitative polymerase chain reaction results showed that dietary FPS ameliorated the lipid accumulation in liver and white adipose tissue (WAT) by inhibiting lipogenesis, enhancing lipolysis, and fatty acid oxidation. FPS exhibited greater efficacy than PS on improving the transcriptional expression of adipose triacylglyceride lipase, carnitine palmitoyltransferase 1, and uncoupling protein 1. In addition, FPS exerted a striking anti-inflammatory effect by suppressing the expression of interleukin 6, interleukin 1β, tumor necrosis factor-α, and transforming growth factor-β in WAT of diabetic C57BL/6 mice. Finally, FPS supplementation enhanced the activation of AMPK. In conclusion, these results suggest that the FPS may be more promising than PS as a potential therapeutic agent for diabetes and obesity.
Dominance-Based Service Selection Scheme with Concurrent Requests
Tang, Chaogang,Li, Qing,Xiong, Yan,Wen, Shiting,Liu, An,Zhong, Farong Korean Institute of Information Scientists and Eng 2012 Journal of Computing Science and Engineering Vol.6 No.2
In dynamic Web service environments, the performance of the Internet is unpredictable; the reliability and effectiveness of remote Web services are also unclear. Therefore, it can hardly be guaranteed that the quality of Web service (QoWS) attributes of Web services do not fluctuate with the dynamic Web service environments. When a composite service is planned in the context of dynamic service environments, there is another aspect which has not been taken into account by existing works, namely, concurrency - the fact that multiple requests to a composite service may arrive at the same time. Considering the dynamics of Web service environments and concurrency of requests, we propose in this paper a service selection scheme which adopts top-k dominating queries to generate a composition solution rather than only select the best composition solution for a given request. The experimental results have investigated the efficiency and effectiveness of our approach and shown that it outperforms baseline and traditional methods for service selection.
Dominance-Based Service Selection Scheme with Concurrent Requests
Chaogang Tang,Qing Li,Yan Xiong,Shiting Wen,An Liu,Farong Zhong 한국정보과학회 2012 Journal of Computing Science and Engineering Vol.6 No.2
In dynamic Web service environments, the performance of the Internet is unpredictable; the reliability and effectiveness of remote Web services are also unclear. Therefore, it can hardly be guaranteed that the quality of Web service (QoWS) attributes of Web services do not fluctuate with the dynamic Web service environments. When a composite service is planned in the context of dynamic service environments, there is another aspect which has not been taken into account by existing works, namely, concurrency - the fact that multiple requests to a composite service may arrive at the same time. Considering the dynamics of Web service environments and concurrency of requests, we propose in this paper a service selection scheme which adopts top-k dominating queries to generate a composition solution rather than only select the best composition solution for a given request. The experimental results have investigated the efficiency and effectiveness of our approach and shown that it outperforms baseline and traditional methods for service selection.
New Polytriazoleimides with High Thermal and Chemical Stabilities
E, Yanpeng,Wan, Liqiang,Li, Yujing,Huang, Farong,Du, Lei Korean Chemical Society 2012 Bulletin of the Korean Chemical Society Vol.33 No.7
A series of novel polytriazoleimides were prepared from various aromatic dianhydrides and a new kind of 1,2,3-triazole-containing aromatic diamine synthesized by the Cu (I)-catalyzed 1,3-dipolar cycloaddition reaction in DMAc, and characterized by FT-IR, $^1H$-NMR, XRD, DSC and TGA techniques. The results show the polytriazoleimides are soluble in most of strong polar solvents and have inherent viscosity values of 0.51-0.62 dL/g(DMAc). The polytriazoleimide films exhibit a tensile strength of 62.3-104.5 MPa and an elongation at breakage of 4.0-8.1%, a glass transition temperature ($T_g$) of $257-275^{\circ}C$, a decomposition temperature (at 5% weight loss) of $350-401^{\circ}C$ in $N_2$ atmosphere, and a dielectric constant of 2.47-3.01 at 10 MHz, which depend on the structure of the polymers. The polytriazoleimides perform good resistance to acid and alkali solution.
New Polytriazoleimides with High Thermal and Chemical Stabilities
Yanpeng E,Liqiang Wan,Yujing Li,Farong Huang,Lei Du 대한화학회 2012 Bulletin of the Korean Chemical Society Vol.33 No.7
A series of novel polytriazoleimides were prepared from various aromatic dianhydrides and a new kind of 1,2,3-triazole-containing aromatic diamine synthesized by the Cu (I)-catalyzed 1,3-dipolar cycloaddition reaction in DMAc, and characterized by FT-IR, 1H-NMR, XRD, DSC and TGA techniques. The results show the polytriazoleimides are soluble in most of strong polar solvents and have inherent viscosity values of 0.51-0.62 dL/g(DMAc). The polytriazoleimide films exhibit a tensile strength of 62.3-104.5 MPa and an elongation at breakage of 4.0-8.1%, a glass transition temperature (Tg) of 257-275 oC, a decomposition temperature (at 5% weight loss) of 350-401 oC in N2 atmosphere, and a dielectric constant of 2.47-3.01 at 10 MHz, which depend on the structure of the polymers. The polytriazoleimides perform good resistance to acid and alkali solution.