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Yan Yang1,Xiaochun Wei,Gongyao Shi,Fang Wei,Janeen Braynen,Jingshu Zhang,Baoming Tian,Gangqiang Cao,Xiaowei Zhang 한국식물학회 2017 Journal of Plant Biology Vol.60 No.2
Success of interspecific hybridization relies mostly on the adequate similarity between the implicated genomes to ensure synapsis, pairing and recombination between appropriate chromosomes during meiosis in allopolyploid species. Allotetraploid Brassica napus (AACC) is a model of natural hybridization between Brassica rapa (AA) and Brassica oleracea (CC), which are originally derived from a common ancestor, but genomic constitution of the same chromosomes probably varied among these species through time after establishment, giving rise to cytogenetic difference in the synthetic hybrids. Herein we investigated meiotic behaviors of A and C chromosomes of synthetic allotriploid Brassica hybrids (ACC) at molecular and cytological levels, which result from the interspecific cross between natural B. napus (AACC) and B.oleracea (CC), and the results showed that meiosis course was significantly aberrant in allotriploid Brassica hybrids, and chromosomes aligned chaotically at metaphase I, chromosome bridges and lags were frequently observed from later metaphase I to anaphase II during meiosis. Simultaneously, we also noticed that meiosis-related genes were abruptly down-regulated in allotriploid Brassica hybrids, which likely accounted for irregular scenario of meiosis observed in these synthetic hybrids. Therefore, these results indicated that inter-genomic exchanges of A and C chromosomes could occur frequently in synthetic Brassica hybrids, and provided an efficient approach for genetic changes of homeologous chromosomes during meiosis in polyploid B.napus breeding program.
Electrochemical control of the conversion of cellulose oligosaccharides into glucose
Fang Yang,Qian Zhang,Hong-Xian Fan,Yang Li,Gang Li 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.5
This paper presents a novel method to convert cellulose oligosaccharides to glucose by using constant-potential electrolysis. Firstly experiments were performed to seek the optimum conditions and catalyst dosage to make the catalytic electrode, and it is found that the most active catalytic electrode (g-MnO2/graphite/PTFE) can be made using 5% g-MnO2 as catalysts which is prepared at calcinations temperature of 500 8C and calcinations time of 3 h. Following this, experiments were conducted to find the optimum operation conditions for the maximum glucose yield using the above-developed catalytic electrode. The results show that the maximum glucose yield of 72.4% can be achieved under the following operation conditions: electrolysis potential vs. SEC 1.0 V, pH value of 3 and electrolytic reaction time of 8 h. The cyclic voltammetry performance on MnO2/graphite/PTFE electrode suggests that g-MnO2 acts not only as electrode material but also as a catalyst. The g-MnO2 displays high electrocatalytic activity toward the breakage of b-1,4-glycoside bond of oligosaccharides and gives 100% selectivity to glucose. Crown Copyright
Lin Fang,Fei-Hu Yan,Chao Liu,Jing Chen,Dan Wang,Chun-Hui Zhang,Chang-Jie Lou,Jie Lian,Yang Yao,Bo-Jun Wang,Rui-Yang Li,Shu-Ling Han,Yi-Bing Bai,Jia-Ni Yang,Zhi-Wei Li,Yan-Qiao Zhang 대한암학회 2021 Cancer Research and Treatment Vol.53 No.1
Purpose Systemic inflammatory response is a critical factor that promotes the initiation and metastasis of malignancies including pancreatic cancer (PC). This study was designed to determine and compare the prognostic value of neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), and fibrinogen-to-albumin ratio (FAR) in resectable PC and locally advanced or metastatic PC. Materials and Methods Three hundred fifty-three patients with resectable PC and 807 patients with locally advan-ced or metastatic PC were recruited in this study. These patients were classified into a training set (n=758) and a validation set (n=402). Kaplan-Meier survival plots and Cox proportional hazards regression models were used to analyze prognosis. Results Overall survival (OS) was significantly better for patients with resectable PC with low preoperative PLR (p=0.048) and MLR (p=0.027). Low FAR, MLR, NLR (p < 0.001), and PLR (p=0.003) were significantly associated with decreased risk of death for locally advanced or metastatic PC patients. FAR (hazard ratio [HR], 1.522; 95% confidential interval [CI], 1.261 to 1.837; p < 0.001) and MLR (HR, 1.248; 95% CI, 1.017 to 1.532; p=0.034) were independent prognostic factors for locally advanced or metastatic PC. Conclusion The prognostic roles of FAR, MLR, NLR, and PLR in resectable PC and locally advanced or metastatic PC were different. FAR showed the most prognostic power in locally advanced or metastatic PC. Low FAR was positively correlated with OS in locally advanced or metastatic PC, which could be used to predict the prognosis.
Fang Deng,Hua-Lin Yang,Long-Jin Wang,Wei-Min Yang 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.12
This paper presents the schemes of nonlinear offset-free model predictive control (MPC) for reference tracking of ship dynamic positioning (DP) systems, in the presence of slow-varying stochastic disturbances and input constraints. Two offset-free MPC strategies for nonlinear DP systems are proposed. The first approach, namely, the target calculation formulation, estimates the disturbance based on the augmented disturbance model, and employs a target calculator to address the MPC optimization problem. The second approach, namely, the delta input formulation, works with the augmented velocity model to lump the effects of disturbances into the input estimates. By successively on-line linearizing the state-space model at the current operating point, the future outputs are explicitly predicted, and then the nonlinear optimization problem becomes an easy quadratic optimization problem. The unscented Kalman filter is adopted for the state estimation. By implementing simulations for two scenarios of disturbances with parametric plant-model mismatch, the effectiveness of the two strategies is demonstrated. Results show that the closed-loop control performance of the delta input formulation method is superior, for its good robustness to the stochastic disturbance.
Fang Deng,Hua-Lin Yang,Long-Jin Wang 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.3
A novel adaptive unscented Kalman filter (AUKF) is presented and applied to ship dynamic positioning(DP) system with model uncertainties of time-varying noise statistics, model mismatch and slow varying driftforces. The adaptive algorithm is proposed to simultaneously online adapt the process and measurement noisecovariance by adopting the main principle of covariance matching. The measurement noise covariance is adaptedbased on residual covariance matching method, and then the process noise covariance is adjusted by using adaptivescaling factor. Simulation comparisons among the proposed RQAUKF, the strong tracking UKF (RSTAUKF) andthe standard UKF show that the proposed RQAUKF can effectively improve the estimation accuracy and stability,and can assist the controller to obtain better control performance.
Fang, Chiew San,Oh, Kyung Hwan,Oh, Aram,Lee, Kwangyeol,Park, Seonhwa,Kim, Sinyoung,Park, Jin Kyoon,Yang, Haesik The Royal Society of Chemistry 2016 Chemical communications Vol.52 No.34
<P>This communication reports a new nanocatalytic scheme based on the facts that the redox reaction between a highly outer-sphere-reaction-philic (OSR-philic) species and a highly inner-sphere-reaction-philic (ISR-philic) species is slow and that an OSR-and ISR-philic Au-nanocatalyst label can mediate the two different types of redox species. This scheme allows highly sensitive and incubation free detection of creatine kinase-MB.</P>
Preparation of decorative slag glass-ceramics and research on the solidification of heavy metals
Yang Tang,Xiaodong Hao,Zhenxiang Fang,Xinyu Bai,Guangyu Wang,Hongxia Zhang,Leibo Deng,Hua Chen,Ming Zhao,Yongsheng Du 한양대학교 청정에너지연구소 2023 Journal of Ceramic Processing Research Vol.24 No.1
Glass-ceramics with different CuO additions were prepared with Fe2O3 and Cr2O3 as composite nucleating agents, rare earthcontainingblast furnace slag (REBFS) as the main raw material. The existence state and stability of heavy metals Cu, Mn andCr in glass-ceramics were investigated. The results showed that Cr ions contributed to the generation of spinel phase, whileCu ions and Mn ions can enter the spinel crystal and exist stably, which indicated that there was a synergistic solidificationof Cu, Mn and Cr. The depolymerization effect of the copper ions contributed to the transformation of the crystal morphologyfrom dendrites to spherulites. Moreover, the increase in CuO contents promoted glass-ceramics from green to copper red. Based on the leaching experimental data analysis of heavy metals in glass-ceramics, the leaching concentration of heavy metalsCu, Cr and Mn were much lower than the standard leaching toxicity limit of hazardous waste (GB5085.3–2007, China). Theresults showed that the conversion of REBFS into environmentally friendly glass-ceramics can realize solid waste resourceutilization.
Analysis of Covert Network Channel based On Two-stage Condensing Clustering of Density Multilayer
Fang Song,Tan Yang,Wang Yanxian,Chen Lin,Liu Yan 보안공학연구지원센터 2016 International Journal of Future Generation Communi Vol.9 No.8
In order to improve universality of detection effect of complex network covert channel, coarsening clustering of channel is achieved, based on clustering algorithm, with hierarchical clustering in this article, then recognition detection of two-stage channel refinement is carried out in coarsening clustering results of each layer based on density clustering. Clustering method of multilayer covert channel is designed based on density, the effectiveness of proposed method is verified by carrying out contrast experiment on density clustering method, entropy method and evaluation method; in the end, experiments of simulation example demonstrate that such algorithm is able to quickly and accurately detect covert channel of complex network when the noise is not higher than 20%.
Yang, Wei,Zhou, Chuwei,Fang, Daining 대한금속재료학회(대한금속학회) 1998 METALS AND MATERIALS International Vol.4 No.4
A numerical micromechanical method is adopted here to investigate the tensile strength of metal matrix composites (MMC) by considering interface and matrix damage evolution. A cohesive zone model is employed to simulate the fiber/matrix interface; damage. The damage in the matrix, which characterizes microvoid nucleation, growth and coalescence, is described in term of the Gurson-Tvergaard material model. These damage models are performed to a boundary value problem that involves a double periodic array of elastic continuous fibers in the elastic-plastic matrix subjected to transverse loads. The main attempt is made to investigate effects of interface strength and toughness on tensile strength of MMC.