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      • KCI등재

        Some Observations of the Influence Factors on the Response of Pile Groups

        Qian-qing Zhang,Shi-min Zhang,Fayun Liang,Qian Zhang,Fei Xu 대한토목학회 2015 KSCE JOURNAL OF CIVIL ENGINEERING Vol.19 No.6

        A simplified approach for nonlinear analysis of the load-displacement response of pile groups embedded in multilayered soils is presented in this work. A hyperbolic model is used to capture the relationship between unit skin friction and pile-soil relative displacement developed along the pile-soil interface and the stress-displacement relationship developed at the pile end. Considering interactive effect among piles, the parameters related to the hyperbolic model of an individual pile in a group can be computed. As to the analysis of the response of pile groups, a highly effective iterative computer program is developed using the hyperbolic model of an individual pile in a group. The efficiency and accuracy of the present method is verified using a well-documented field test. Furthermore, a parametric study is conducted to capture the influence of pile spacing and number of piles on the load-settlement response of the pile groups connected to a rigid cap. The pile-group settlement ratio and the pile-group resistance ratio are analyzed to assess the interaction effect among individual piles.

      • How the International Cooperation in “Sci-tech +Industry” Model Working in Developing Mango as “One Village and One Product”: Citing the Industrial Upgrading Experience in Baihua Village as An Example

        Yanxiu Zuo(Yanxiu Zuo),Junxiang Qian(Junxiang Qian),Lichi Li(Lichi Li),Zhangguan Ni(Zhangguan Ni),Jun Wu(Jun Wu),Huiyun Zhang(Huiyun Zhang),Yufu Chen(Yufu Chen),Huiyun Zhang(Huiyun Zhang),Li Yao(Yao L 아시아사회과학학회 2022 Jornal of Asia Social Science Vol.9 No.1

        Baihua Village is a typical mountainous village in the southwest part of Lujiang county, Longyang District, Baoshan City, Yunnan Province. Residents there made a living on the land, including growing sugarcane and planting maize, whose annual income was no more than 2000 yuan before 2006. Since then when a research institute has set it as one of the pilot villages for mango growing impetus with sci-tech. For the sake of “One village and One Product”, mango breeding and relevant techniques have been applied to daily work. Within years, the developed model of has been explored: simply “villages are the main carriers facilitated by the specialized cooperative for mango growing, back-up by science and technology. Technical trainings serve as the driving force for the leading growers, meanwhile, sellers work as the bridge link the producing-end and the markets”.

      • SCOPUSKCI등재

        Studies on the Small Body Size Mouse Developed by Mutagen N-Ethyl-N-nitrosourea

        Zhang, Qian-Kun,Cho, Kyu-Hyuk,Cho, Jae-Woo,Cha, Dal-Sun,Park, Han-Jin,Yoon, Seok-Joo,Zhang, ShouFa,Song, Chang-Woo Korean Society of ToxicologyKorea Environmental Mu 2008 Toxicological Research Vol. No.

        Mutant mouse which show dwarfism has been developed by N-ethyl-N-nitrosourea (ENU) mutagenesis using BALB/c mice. The mutant mouse was inherited as autosomal recessive trait and named Small Body Size (SBS) mouse. The phenotype of SBS mouse was not apparent at birth, but it was possible to distinguish mutant phenotype from normal mice 1 week after birth. In this study, we examined body weight changes and bone mineral density (BMD), and we also carried out genetic linkage analysis to map the causative gene(s) of SBS mouse. Body weight changes were observed from birth to 14 weeks of age in both affected (n = 30) and normal mice (n = 24). BMD was examined in each five SBS and normal mice between 3 and 6 weeks of age, respectively. For the linkage analysis, we produced backcross progeny [(SBS${\times}$C57BL/6J) $F_1{\times}$ SBS] $N_2$ mice (n = 142), and seventy-four microsatellite markers were used for primary linkage analysis. Body weight of affected mice was consistently lower than that of the normal mice, and was 43.7% less than that of normal mice at 3 weeks of age (P < 0.001). As compared with normal mice at 3 and 6 weeks of age, BMD of the SBS mice was significantly low. The results showed 15.5% and 14.1 % lower in total body BMD, 15.3% and 8.7% lower in forearm BMD, and 29.7% and 20.1% lower in femur BMD, respectively. The causative gene was mapped on chromosome 10. The map order and the distance between markers were D10Mit248 - 2.1 cM - D10Mit51 - 4.2 cM - sbs - 0.7 cM - D10Mit283 - 1.4cM - D10Mit106 - 11.2cM - D10Mit170.

      • KCI등재

        Flowing Water Editing and Synthesis Based on a Dynamic Texture Model

        Zhang, Qian,Lee, Ki-Jung,WhangBo, Taeg-Keun Korea Multimedia Society 2008 멀티미디어학회논문지 Vol.11 No.6

        Using video synthesis to depict flowing water is useful in virtual reality, computer games, digital movies and scientific computing. This paper presents a novel algorithm for synthesizing dynamic water scenes through a sample video based on a dynamic texture model. In the paper, we treat the video sample as a 2-D texture image. In order to obtain textons, we analyze the video sample automatically based on dynamic texture model. Then, we utilize a linear dynamic system (LDS) to describe the characteristics of each texton. Using these textons, we synthesize a new video for dynamic flowing water which is prolonged and non-fuzzy in vision. Compared with other classical methods, our method was tested to demonstrate the effectiveness and efficiency with several video samples.

      • KCI등재

        Local Joule heating targets catalyst surface for hydrocarbon combustion

        Qian Xiong,Xingbao Zhu,Ri He,Xueyi Mei,Yexin Zhang,Zhicheng Zhong,Wei Zhao,Weiming Nie,Jian Zhang 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.117 No.-

        Most industrial catalytic reactions are achieved by external heating and catalysts are entirely heated tooffer enough thermal energy to surface active sites. However, there is an inherent drawback that mostinput energy is dissipated into the bulk while minor is donated to the surface, leading to high energywaste. Here, we proposed a so-called local Joule heating method via passing an electric current throughpacked catalyst nanoparticles with a large contact resistance, which can generate sufficient heat to targetat the surface region. We selected hydrocarbon combustion, a common way to eliminate unburned pollutants,as a probe reaction and used the conductive antimony-doped tin oxide (ATO) as a model catalyst. Compared with traditional external heating, this method consumed one order lower energy input,reduced the macroscopically average temperature for same conversion by 100 C, improved the durabilitywith smaller activity loss within 100 h operation, and suppressed water poisoning effect by 60 %. Also, the combustion was sparked in seconds by pulsing electric current into the catalyst bed, allowing anapplication in prompt treatment of leaked hydrocarbons. The local Joule heating between contactednanoparticles, which could focus thermal energy on catalyst surface, is prospective to improve catalysisefficiency.

      • Irinotecan as a Second-line Chemotherapy for Small Cell Lung Cancer: a Systemic Analysis

        Zhang, Ming-Qian,Lin, Xin,Li, Yan,Lu, Shuang Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.5

        Purpose: This analysis was conducted to evaluate the efficacy and safety of irinotecan based regimens as second-line chemotherapy in treating patients with small cell lung cancer. Methods: Clinical studies evaluating the efficacy and safety of irinotecan based regimens as second-line chemotherapy for patients with small cell lung cancer were identified using a predefined search strategy. Pooled response rates (RRs) of treatment were calculated. Results: In irinotecan based regimens as second-line chemotherapy, 4 clinical studies which including 155 patients with small cell lung cancer were considered eligible for inclusion. In all chemotherapy consisted of irinotecan with or without nedaplatin. Pooled analysis suggested that, in all patients, the pooled RR was 27.1% (42/155) in irinotecan based regimens. Nausea, vomiting, diarrhea and myelosuppression were the main side effects. No grade III or IV renal or liver toxicity was observed. No treatment related death occurred with the irinotecan based treatments. Conclusion: This systemic analysis suggests that irinotecan based regimens as second-line chemotherapy are associated with mild response rate and acceptable toxicity for patients with small cell lung cancer.

      • KCI등재

        Molybdate Alters Sulfate Assimilation and Induces Oxidative Stress in White Clover (Trifolium repens L.)

        Zhang, Qian,Lee, Bok-Rye,Park, Sang-Hyun,Jeong, Gi-Ok,Kim, Tae-Hwan The Korean Society of Grassland and Forage Science 2013 한국초지조사료학회지 Vol.33 No.3

        Molybdenum (Mo) in rhizosphere influences sulfate assimilation as well as a number of other physiological aspects. In this study, the activity of key enzymes in sulfate assimilatory pathways, such as ATP sulfurylase (ATPs), adenosine 5'-phosphosulphate reductase (APR), as well as the responses of reactive oxygen species (ROS), were analyzed to elucidate the metabolic and physiological effects of external Mo supply to detached leaves of Trifolium repens L. Mo supply with a range from 1 mM to 40 mM depressed the activity of ATPs throughout the entire time course. In the leaves exposed to 1 mM Mo, a continuous decrease in the activity of ATPs was confirmed by Native-PAGE. The APR activity was also declined by Mo treatment. The accumulation of $H_2O_2$ and ${O_2}^{{\cdot}-}$ were not significant up to 10 mM Mo, whereas a remarked accumulation was detected under 40 mM Mo supply. The data suggest that an external supply of Mo has an inhibitory effect on sulfate assimilation, and induces oxidative stress only at an extremely high concentration.

      • Risk identification, assessment and monitoring design of high cutting loess slope in heavy haul railway

        Zhang, Qian,Gao, Yang,Zhang, Hai-xia,Xu, Fei,Li, Feng Techno-Press 2018 Structural monitoring and maintenance Vol.5 No.1

        The stability of cutting slope influences the safety of railway operation, and how to identify the stability of the slope quickly and determine the rational monitoring plan is a pressing problem at present. In this study, the attribute recognition model of risk assessment for high cutting slope stability in the heavy haul railway is established based on attribute mathematics theory, followed by the consequent monitoring scheme design. Firstly, based on comprehensive analysis on the risk factors of heavy haul railway loess slope, collapsibility, tectonic feature, slope shape, rainfall, vegetation conditions, train speed are selected as the indexes of the risk assessment, and the grading criteria of each index is established. Meanwhile, the weights of the assessment indexes are determined by AHP judgment matrix. Secondly, The attribute measurement functions are given to compute attribute measurement of single index and synthetic attribute, and the attribute recognition model was used to assess the risk of a typical heavy haul railway loess slope, Finally, according to the risk assessment results, the monitoring content and method of this loess slope were determined to avoid geological disasters and ensure the security of the railway infrastructure. This attribute identification- risk assessment- monitoring design mode could provide an effective way for the risk assessment and control of heavy haul railway in the loess plateau.

      • SCIESCOPUSKCI등재

        Controlled-Type ZVS Technique without Auxiliary Components for Micro-inverters

        Zhang, Qian,Zhang, Dehua,Hu, Haibing,Shen, John,Batarseh, Issa The Korean Institute of Power Electronics 2013 JOURNAL OF POWER ELECTRONICS Vol.13 No.6

        This paper proposes a Boundary Current Mode (BCM) control scheme to realize soft switching on a conventional single phase full bridge DC/AC inverter. This technique with the advantages of no auxiliary components, low cost, high efficiency, and simple in control, is attractive for micro-inverter applications. The operation principle and characteristic waveforms of the proposed soft switching technique are analyzed in theory. A digital controller is provided based on that theory. To balance the requirements of efficiency, switching frequency, and inductor size, the design considerations are discussed in detail to guide in BCM inverter construction. A 150W prototype is built under these guidelines to implement the BCM control scheme. Simulation and experiment results demonstrate the feasibilities of the proposed soft switching technique.

      • The catalytic core of DEMETER guides active DNA demethylation in <i>Arabidopsis</i>

        Zhang, Changqing,Hung, Yu-Hung,Rim, Hyun Jung,Zhang, Dapeng,Frost, Jennifer M.,Shin, Hosub,Jang, Hosung,Liu, Fang,Xiao, Wenyan,Iyer, Lakshminarayan M.,Aravind, L.,Zhang, Xiang-Qian,Fischer, Robert L. National Academy of Sciences 2019 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.116 No.35

        <P><B>Significance</B></P><P>Flowering plants reproduce via a unique double-fertilization event, producing the zygote and the nutritive endosperm. The genome of the central cell, the precursor of the endosperm, undergoes extensive demethylation prior to fertilization. This epigenetic reconfiguration, directed by the DEMETER (DME) glycosylase at thousands of loci in <I>Arabidopsis</I>, differentiates the epigenetic landscapes of parental genomes and establishes parent of origin-specific expression of many imprinted genes in endosperm essential for seed development. However, how DME is targeted to various locations remains unknown. Here we show that the multidomain DME is organized into 2 functional regions: the C-terminal region, which guides localization and catalysis, and the N-terminal region, which likely recruits chromatin remodelers to facilitate demethylation within heterochromatin.</P><P>The <I>Arabidopsis</I> DEMETER (DME) DNA glycosylase demethylates the maternal genome in the central cell prior to fertilization and is essential for seed viability. DME preferentially targets small transposons that flank coding genes, influencing their expression and initiating plant gene imprinting. DME also targets intergenic and heterochromatic regions, but how it is recruited to these differing chromatin landscapes is unknown. The C-terminal half of DME consists of 3 conserved regions required for catalysis in vitro. We show that this catalytic core guides active demethylation at endogenous targets, rescuing <I>dme</I> developmental and genomic hypermethylation phenotypes. However, without the N terminus, heterochromatin demethylation is significantly impeded, and abundant CG-methylated genic sequences are ectopically demethylated. Comparative analysis revealed that the conserved DME N-terminal domains are present only in flowering plants, whereas the domain architecture of DME-like proteins in nonvascular plants mainly resembles the catalytic core, suggesting that it might represent the ancestral form of the 5mC DNA glycosylase found in plant lineages. We propose a bipartite model for DME protein action and suggest that the DME N terminus was acquired late during land plant evolution to improve specificity and facilitate demethylation at heterochromatin targets.</P>

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