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      • 시스템 동작의 질적 추론을 위한 구성 요소 분석

        권은아,김홍기 충북대학교 컴퓨터 정보통신 연구소 1997 컴퓨터정보통신연구 Vol.5 No.1

        자연 현상에서 일어나는 변화의 표현은 그 현상에 관련된 물체들의 매개변수 (힘, 속도, 위치, 압력 등)의 값에 의해 나타나진다. 그러나 자연 법칙하에 움직이는 것이나 어떠한 목적으로 만든 동적인 시스템들의 작동을 추론하는 데에 꼭 수학적 방정식과 같은 양적 묘사가 필요하지 않다. 오히려 상황의 전환 과정을 변수의 비례관계나 영향관계로 나타내는 질적 묘사가 시스템의 작동을 추론하고 이해하는데에 일차적인 도움을 준다. 본 논문에서는 질적 추론을 위해 필요한 시스템 구성 요소에 대하여 연구하고 그 구성 요소들이 시스템 동작의 인과관계를 구성해 나가는데 어떤 역할을 하는지 설명하였다.

      • Mannitol 투여에 의한 핍뇨성 급성 신부전 1례

        이홍준,나기찬,정은경,박상기 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.2

        Mannitol, a hexahydroxy chemically related to mannose, is a non-electrolytic, osmotic agent, It has been known that mannitol may cause serious life-threatening situation if administered in a patient with renal problem. Recently, it has been published that mannitol itself may be nephrotoxic in a patient without preexisting nephrologic disorders. We experienced a case of acute oliguric renal failure caused by long use of mannitol in order to reduce intracranial pressure and cerebral edema after operation of left posterior communicating aneurysm, and reported with recent literature review.

      • 대학생의 기본 심폐소생술 교육 평가 : 간호과와 비간호과를 대상으로

        이정은,고봉연,이인모,최근명,박신일,안홍기 한국응급구조학회 2003 한국응급구조학회지 Vol.7 No.1

        The purpose of this study was to evaluate the accuracy of CPR skills and the satisfaction of CPR Training targeted for college students. Also, this study made comparative study of nursing students and non-nursing students. The sample consisted of 248 students(132 nursing students, 116 non-nursing students). CPR Training was designed by two components which were a lecture and demonstration by one professor and individual practice 표 instructors. As tool of measurement estimation satisfaction of CPR Training questionnaires were developed based on educated contents. The accuracy of CPR skills were checked by SkillReporter CPR training manikin. Collected data were computerized and analyzed by SPSS-WIN program. The results were as follows : 1. The skills of CPR were cardiac compression 92.79 times/min, correct cardiac compression rate 90.85%, ventilation 9.93 times/min. correct ventilation rate 79.34%. 2. The mean of the accuracy of CPR skills were 2.94(SD .87). 3. When errors were analyzed, the highest item was stomach distension(51.2%) of ventilation skills and too little(70.6%) of cardiac compression skills. 4. The mean of the satisfaction of CPR training were 2.87(SD .17), the highest item of the satisfaction of CPR Training was practice. 5. We found significant statistical differences based on the accuracy and the error, non-nursing students were high in correct cardiac compression per minute(t=3.615, p=0...) and ventilation too much(t=4.292, p=.000), nursing students were high in correct ventilation rate(t=-3.885, p=.000) and cardiac compression too shallow) t=-2.842, p=.005).

      • 난소에 전이된 간세포암 1예

        박용관,박치영,조은택,조기섭,박찬국,송창훈,이미자,기근홍 朝鮮大學校 附設 醫學硏究所 1995 The Medical Journal of Chosun University Vol.20 No.2

        Hepatocellular carcinoma frequently metastasizes through direct extension, lymphatic, and hematogenous routes. The most common sites of metastasis are the lungs and the lymph nodes, glands, bones, spleen, kidneys, colon, and pleura are the sites of metastasis in decreasing order of frequency. But metastasis to the ovary is very rare. It is thought that metastasize to the ovary occurs through infiltration or dissemination. However, we observed ovarian metastasis of primary hepatic tumor in a 34-year old female who suffered from lower abdominal pain. At first, it was diagnosed as a primary ovarian tumor. But histologically, it presented sinusoidal pattern surrounded by the tumor cells and contained rounded by the tumor cells and contained round hyaline globules in minority of the cytoplasm. Then, the histologic features of percutaneous, sono-guided liver biopsy speecimen of the liver mass are similar to those of resected ovarian tissues. Therefore, we concluded that ovarian tumor was originated from hepatocellular carcinoma. In summary, this report examines a case of hepatocellular carcinoma with ovarian metastasis in a female and reviews the literature.

      • KCI등재

        한국 정신장애의 역학 조사 연구[I] : 각 정신장애의 유병률

        조맹제,함봉진,김장규,박강규,정은기,서동우,김선욱,조성진,이준영,홍진표,최용성,박종익,이동우,이기철,배재남,신정호,정인원,박종한,배안,이충경 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4

        Objectives : This study aims to estimate the prevalence of the DSM-IV psychiatric disorders in Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI). Methods : Subjects were selected by taking multi-stage, cluster samples of 7,867 adult household residents, 18 to 64 years of age, in ten catchment areas. Total 78 trained interviewers administered the K-CIDI to the selected respondents, from June 1 to November30,2001. Results : Total 6,275 respondents completed the interview. Some 33.5% of respondents reported at least one lifetime disorder, 20.6% reported at least one-year disorder, and 16.7% reported at least one-month disorder. The most common lifetime disorders were alcohol abuse/dependence (17.24%), nicotine dependence/withdrawal (11.19%), specific phobia (5.16%), and major de-pressive disorder (4.25%). The lifetime prevalence of substance abuse/dependence (0.25%) and schizophrenia (0.16%) was very low. Nicotine and alcohol use disorder showed very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among female than male. Conclusion : The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in distributions of psychiatric disorders across the areas and times were observed.

      • [P528] A case of digital mucous cyst treated by surgical ligation with use of methylene blue dye

        ( Seung Gi Hong ),( Sung Eun Song ),( Sun Young Jo ),( Eun Phil Heo ),( Ki Woong Rho ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

        Digital mucous cyst (DMC) is relatively common, benign pseudocysts of the digits typically located at the distal interphalangeal joint (DIPJ) or in the proximal nail fold caused by leakage of fluid from the joint into the surrounding tissues. DMCs present as solitary, and round to oval cystic nodular lesion on the digits of the hand. Various modalities such as aspiration of cyst, cryosurgery, CO2 laser therapy, surgical excision and surgical ligation are applied to treat DMC. Among them, surgical ligation is considered a effective therapy of DMCs because of its high cure rate. It is important to identify the site of the communication between the DIPJ and the cyst. Injection of methylene blue into the DIPJ is helpful to identify the site. This case is about 47-year-old female patient who had been diagnosed as DMC and underwent cryotherapy at 2 years before visiting our clinic. However, DMC was not cured, and she visited our hospital. We attempted to treat cysts by sealing the leakage point. Methylene blue dye is first injected into the DIPJ. Then, a skin flap is raised around the cyst to find the area of dye-filled communication between the joint space and the cyst. This communication is then sutured and the flap is dropped back into place without tissue resection. Methylene blue injection is a convenient method for the complete removal of highly relapsing DMC.

      • Histopathologic review of longitudinal melanonychia: single secondary referral center

        ( Seung Gi Hong ),( Sun Young Jo ),( Han Him Jeong ),( Hong Pil Jeong ),( Hyun Joo Lee ),( Jae Wan Go ),( Eun Phil Heo ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.2

        Background: Longitudinal melanonychia is characterized by pigmented bands on the nail plate. It caused by deposition of either melanin or other substances, and associated with activation or proliferation of nail matrix melanocytes. Objectives: We aimed to evaluate the histopathological findings of longitudinal melanonychia in Korean single secondary referral center patients. Methods: In our study, 46 patients with longitudinal melanonychia who visited our clinic from January 2012 to December 2018 were included. We retrospectively reviewed the histopathologic findings that confirmed by biopsy in 47 cases of longitudinal melanonychia. Results: Of the 47 affected nail plates, 33 (70.2%) were fingernails, and longitudinal melanonychia was detected most frequently in the left 1st fingernail (25.5%). Nail matrix nevus was most common (28.3%), followed by subungual melanoma (26.1%), and nail apparatus lentigo (21.7%). 13 patients (28.3%) diagnosed with malignancy, including one with basal cell carcinoma, and 76.9% (10/13 patients) showed a positive Hutchinson’s sign were diagnosed with malignancy. There were 4 patients with accompanying nail plate deformation or ulcers, and of these, 2 patients (50%) were diagnosed with malignancy. Conclusion: This study presented variable histopathologic features of longitudinal melanonychia. We should be considering various conditions as well as melanoma, and determine the appropriate management in patients with longitudinal melanonychia.

      • KCI등재

        Real-Time PCR법과 LC/MS법을 이용한 수계중의 마이크로시스틴 검출방법 비교연구

        박홍기(Hong-Gi Park),정미은(Mi-Eun Jung),차동진(Dong-Jin Cha),정은영(Eun-Young Jung),빈재훈(Jae-Hoon Bean) 한국생명과학회 2010 생명과학회지 Vol.20 No.8

        현장의 환경 시료를 대상으로 Real-Time PCR법과 LC/MS법을 이용하여 마이크로시스틴 검출방법을 비교 연구하였다. 3종류의 primer쌍을 이용하여 3종의 Microcystis aeruginosa 표준균주를 대상으로 Real-Time PCR법을 실시한 결과 TOX2P/TOX2M primer를 이용한 균주에서만 마이크로시스틴이 검출되었다. 2009년 6~9월 사이에 남조류가 발생한 상수원수 시료를 정립된 Real-Time PCR법과 기존의 LC/MS법으로 실험한 결과 11개 시료 모두에서 마이크로시스틴이 검출되었고, 농도는 5.98~219.0 ㎍/l 범위로 조사되었다. 정수처리 공정별 실험에서는 BAC 여과 단계에서 마이크로시스틴이 완전히 제거되는 것으로 나타났다. 실험결과 Real-Time PCR법은 기존의 표준시험방법인 LC/MS법 보다 분석시간을 많이 단축시키는 것으로 나타나 효과적인 마이크로시스틴 검출방법임을 알 수 있었다. We performed a comparative analysis using a Real-time PCR (Polymerase Chain Reaction) and LC/MS (Liquid-Chromatograph/Mass Spectrometer) method in order to detect microcystin in environmental sources. Among the three different primer sets tested for microcystin using three positive strains of Microcystis aeruginosa by Real-time PCR assay, only TOX2P/TOX2M primer pairs were able to detect Microcystis aeruginosa. According to the results of a survey carried out from June 2009 to September 2009, 11 out of 11 (100%) raw water samples were were found to have microcystin when the Real-Time PCR and LC/MS method was used, with total microcystin concentration ranging from 5.98~219.0 ㎍/l. A microcystin removal treatment process was used to ensure entire removal, by passing it through a BAC filtration step. It was concluded that real-time PCR assay can be used to estimate micrucystin detection more rapidly and easily than the LC/MS method.

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