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Adiramycin이 C6 glioma 세포에 미치는 영향에 대한 원지의 효과
이은미,최유선,손영우,유교상,하대호,이환봉,장철호,이정헌,이강창,이승현,박승택,이건목,류도곤 대한동의생리학회,대한동의병리학회 2001 동의생리병리학회지 Vol.15 No.6
To elucidate the cytotoxic effect of adriamycin on C6 glioma cells, we examined the neurotoxicity induced by adriamycin by MTX assay when C6 glioma cells were cultured in the media containing various concentrations of adriamycin for 72 hours. In addition, neuroprotective effects of herb extract such Polygalae Radix(PR), on adriamycin-induced neurotoxicity in cultured C6 glioma cells were evaluated after C6 glioma cells were preincubated with various concentrations of herb extract, PR for 2 hours before 6uM adriamycin for 72 hours. Adriamycin decreased remarkably cell viability in dose-and time-dependent manner in these cultures, and also herb extract, PR increased cell viability of C6 glioma cells damaged by adriamycin. From these results, it is suggested that adriamycin was highly toxic in cultured C6 glioma cells, and PR was effective in blocking the neurotoxicity induced by adriamycin in these cultures.
이재규,이은미,오석규,손영우,유교상,김상수,이정헌,이강창,한두석,이승현,박승택,김요한,송호준 대한동의생리학회,대한동의병리학회 2001 동의생리병리학회지 Vol.15 No.6
In order to clarify the cytotoxic effect of cadmium in cultured oligodendrocytes of neonatal mouse, the cytotoxicity was measured by MTX assay in cultured cells treated with 1∼20uM CdCl_2 for 24 hours. And also, the protective effect of Achyranthis Bidentazae Radix(ABR) was examined by cell viability in these cultures. Cell viability was significantly decreased in a dose-and time-dependent manner after exposure of cultured oligodendrocytes to 10uM CdCl_2 for 24 hours. Protective effect of ABR on CdCl_2-mediated toxicity was very effective in these cultures. From above the results, it suggests that CdCl_2 is toxic in cultured oligodendrocytes and selective herb extract such as ABR is effective in protection of the CdCl_2 -induced cytoxicity.
한국인의 비타민 D 수준에 따른 페리틴, 헤모글로빈 농도
박주원(Juwon Park),배은진(Eun Jin Bae),이택현(Taeck-hyun Lee),진우성(Woo Sung Jin),최현희(Hyunhee Choi),양정숙(Jeong Sook Yang),홍지은(Ji Eun Hong) 한국산학기술학회 2016 한국산학기술학회논문지 Vol.17 No.9
본 연구는 제 4기, 제 5기 국민건강영양조사 자료를 이용하여 18세 이상 성인 23577 명을 남성 전체와 여성 전체, 65세 이상 남성과 65세 미만 남성, 폐경 전 여성과 폐경 후 여성으로 나누어 비타민 D의 수준에 따라 헤모글로빈과 페리틴 농도의 변화가 어떤 차이를 보이는지 알아보고자 하였다. 각 조사 대상 군을 비타민 D의 수준에 따라 5분 위수로 나누어 각 군 별 헤모글로빈과 페리틴 농도의 변화를 복합표본설계방법에 따라 일반선형모형을 사용하여 분석하였고 분석 결과 여성 전체 군(p<0.001)과 폐경 전 여성 군(p<0.001)에서 비타민 D 수준에 따라 헤모글로빈 농도의 차이가 통계적으로 유의하였고 폐경 후 여성 군과 남성 전체 및 65세 이상 남성, 65세 미만 남성 군에서는 통계적으로 유의하지 않았다. 페리틴 농도는 여성 전체 군(p<0.001)과 폐경 전 여성 군(p<0.001)과 남성 전체 군(p<0.05), 65세 미만 남성 군(p<0.05))에서 통계적으로 유의한 차이를 나타냈으나 남성에서 비타민 D가 높은 그룹이 페리틴이 낮았던 반면 여성에서는 비타민 D가 높은 그룹이 페리틴 농도가 더 높았고, 폐경 후 여성 군과 65세 이상 군에서 통계적으로 유의하지 않았다. 따라서 비타민 D는 폐경 전 여성에서 헤모글로빈 농도에 영향을 줄 가능성이 있고 폐경 전 여성과 65세 미만 남성의 체내 철 조절에 관여할 가능성이 있다. This study is designed to investigate the differences of ferritin and hemoglobin levels according to the vitamin D state in 23577 Korean adult subjects by using data from the Korea National Health and Nutrition Examination Survey IV, V. Ferritin and hemoglobin levels are analyzed based on the quintile of vitamin D levels by a generalized linear model. The results of analysis showed that there was a relationship between vitamin D state and hemoglobin levels in females in the reproductive status group (p<0.001). In case of ferritin, there was a relationship with vitamin D state in females in reproductive status group (p<0.001) and males under 65 years old group (p<0.05). Within the male group, high ferritin correlated with low vitamin D state; but in the female group, high ferritin correlated with high vitamin D state. Therefore, it is possible for the ferritin level to be affected by vitamin D state in females in reproductive status group and males under 65 years old group.
수소충전소의 연료 계량 방법에 따른 계량 오차가 발생하는 원인 고찰
이택홍,강병우,이은웅,정진배,홍석진,LEE, TAECK HONG,KANG, BYOUNG WOO,LEE, EUN WOUNG,CHUNG, JIN BAE,HONG, SUK JIN 한국수소및신에너지학회 2018 한국수소 및 신에너지학회논문집 Vol.29 No.1
There has been an measuring errors between state of charge (SOC; kg) value and mass flow meter (MFM) value in dispenser for hydrogen refueling station. Finally, we observed average 15.5% weight difference between these two values and the MFM readings show a 15.5% higher readout of the SOC readings. Each car was charged with average 2.66 kg of hydrogen fuel during this period. In the initial charging of the day shows less measuring value than the final charging with the maximum 0.038 kg times number of filling. There is no effects of atmosphere temperature change for the hydrogen filled weight during one full year such as January's cold winters and August's hot summers.