충남대학교병원 마취발전의 경향에 관한 분석 : 1967년부터 - 1996년까지 from 1967 to 1996

최세진,김상수,정규돈,윤석화,신용섭,손수창,이원형,김혜자,이정은 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.2

To evaluate the specificity and historical trends of the anesthesia in Chungnam National University Hospital, anesthetic experiences of 83,572 in total performed at Chungnam National University Hospital from January 1967 to December 1996 were analyzed statistically and clinically according to age, sex, surgical department, physical status, elective and emergency surgery, premedicants, IV anesthetics, anesthetic methods, inhalational anesthetics, muscle relaxants. The results were as follows : 1. The number of cases has been steadily increased year by year. 2. The ratio of male to female was 52.8% : 47.2%. 3. According to the age, There were 44,905 cases (54%) in the group of 13-45 years. 4. According to the ASA classification of physical status, most of the cases were belonged to the class 1 & 2 (72.5%). 5. The ratio of elective to emergency was 79.4% to 20.6%. 6. Recently, glycopyrrolate has been used increasingly. 7. Thiopental sodium has been mainly used for intravenous induction agent. 8. General anesthesia has been used mainly. 9. Enflurane is the most common inhalational anesthetic agent. but Isoflurane has been used increasingly. 10. Most of muscle relaxants are Pancuronium & Vecuronium(84.5%).

대두유 첨가 냉동저장 녹두전분겔의 품질특성

최은정, 오명숙 가톨릭대학교 생활과학연구소 2011 생활과학연구논집 Vol.31 No.1

다발성 골수종

최은숙,고광준 大韓口腔顎顔面 放射線學會 1993 Imaging Science in Dentistry Vol.23 No.2

This is a report of multiple myeloma occurred in the left mandibular body and skull. 66-year-old patient was referred to our hospital with a complaint of painful swelling on the left mandibular body area. The author diagnosed it as a multiple myeloma by the clinical examination, radiographic findings, laboratory findings and the histopathological findings. The purpose of this report is to aid in the diagnosis of multiple myeloma and to aid to differentiate it from malignant tumours. The characteristic features are as follows: 1. In clinical examination, painful swelling was observed in left mandibular body area. 2. In radiographic findings, radiograms showed relatively ill-defined radiolucency without sclerotic border in left mandibular body area. And also represented multiple punched-out radiolucency in the skull and pathologic fracture of vertebral body on lumbar 3 level. 3. In histopathologic findings, infiltration of abnormal plasma cells was observed. 4. In laboratory findings, decreasing of albumin/globulin ratio, hypercalcemia, renal impairment was observed, but we could not find the Bence-Jones protein in urin.

안면골 외상환자의 전산화단층상을 이용한 삼차원재구성상의 비교 연구

최은숙,고광준 大韓口腔顎顔面 放射線學會 1994 Imaging Science in Dentistry Vol.24 No.2

The purpose of this study was to clarify the spatial relationship in presurgical examination and to aid surgical planning and postoperative evaluation of patients with facial bone injury. For this study, three-dimensional images of facial bone fracture were reconstructed by computed image analysis system and three-dimensional reconstructive program integrated in computed tomography. The obtained results were as follows: 1. Serial conventional computed tomograms were value in accurately depicting the facial bone injuries and three-dimensional reconstructive images demonstrated an overall look. 2. The degree of deterioration of spatial resolution was proportional to the thickness of the slice. 3. Facial bone fractures were the most distinctly demonstrated on inferoanterior views of three-dimensional reconstructive images. 4. Although three-dimensional reconstructive images made diagnosis of fracture lines, it was difficult to identify maxillary fractures. 5. The diagnosis of zygomatic fractures could be made equally well with computed image analysis system and three-dimensional reconstructive program integrated in computed tomography. 6. The diagnosis of mandibular fractures could be made equally well with computed image analysis system and three-dimensional reconstructive program integrated in computed tomography.

상악골에 발생된 연골형성형 측피질골육종

최선영,고광준,최은숙 大韓口腔顎顔面 放射線學會 1998 Imaging Science in Dentistry Vol.28 No.2

39-year-old female had been treated for the exophytic mass on buccal aspect of the left maxillary posterior area 2 years and 8 months ago. Tentative diagnosis was obtained as fibrous dysplasia on clinical and radiographic examinations and histopathologic findings revealed as osteochondroma after bone trimming at that time. She revisited for the treatment of recurred lesions. We reviewed this case with clinical, radiologic and histopathologic standpoints retrospectively, and came to a conclusion that the tumor primarily occurred was juxtacortical osteogenic sarcoma and recurred due to inadequate treatment and then expanded over intramedullary. This case shows that the diagnosis of osteosarcoma should take account of the patient history, clinical, radiographic and histopathologic findings and it requires attentive follow up check. Retrospectively reviewed results were as follows ; At first visit, oral examination revealed a bony hard swelling on the buccal aspect of the left maxillary posterior area. Radiographically, a dense radiopaque mass was noted on the site. The lesion showed hot uptake of? Tc-MDP. Histopathologic diagnosis was done as osteochondroma, but it was considered as osteogenic sarcoma when compared with the recurrent lesion. When she revisited for the treatment of multiple bony swelling on the left maxilla, radiograms showed typical features of malignancy such as widening of periodontal ligament space and sunray appearace, and coincided with benign characters as follows ; relatively well circumscribed lesion and expansion and displacement of the adjacent structures. Finally, histopathologic findings of the lesion was well differentiated chondroblastic osteogenic sarcoma.

정맥내 주사로 인한 정맥염 발생의 다기관 공동 역학 조사 : 서울, 경기도 6개 종합병원을 대상으로:Focused on 6 hospitals in Seoul or Gyonggi-do, Korea

최정실,박은숙,진혜영,정선영,박미라,김정은,김금순 대한병원감염관리학회 2003 의료관련감염관리 Vol.8 No.2

만성 재발성 소아 흉통의 원인 질환과 임상양상

최은정,이은아,이창우,최두영,오연균,김종덕,윤향석 대한소아과학회 2004 小兒科 Vol.47 No.6

고온충격이 E.coli의 대사산물에 미치는 효과

김은숙,최영길 漢陽大學校 環境科學硏究所 1991 環境科學論文集 Vol.12 No.-

Escherichia coli(E. coli K12 HB101)를 이용하여 고온충격시의 생장곡선, 단백질과 Ribonucleic acid(RNA) 함량을 조사하여 생장율의 변화와 대사산물의 변화를 알아보고자 하였다. 그리고 sodium dodecyl sulfate-polyacrtylamide gel electrophoresis(SDS-PAGE)를 실시하여 새로운 Heat Shock Protein(HSP)의 생성여부와 시간을 조사하고 고온충격에 대한 적응기작으로서 Ribonuclease(RNase)가 유도 되는지의 여부와 RNase 활성도의 변화를 알아보고자 하였다. 실험군은 30℃ 에서 정상배양을 하다가 대수증식기에 도달하면 42℃로 옮긴 후 0분, 5분, 30분, 45분, 60분 간격으로 취하였다. 본 실험에서 고온충격에 따른 생장율의 변화를 보면 30℃ 에서 정상배양한 실험군보다 42℃실험군이 1시간 후로는 ??로 증가하였으며 정체기에 가서는 30℃와 42℃에서의 균체수가 거의 일치하였다. 단백질의 함량은 고온충격후 5분내에 42℃실험군이 30℃실험군보다 약 4.5배 증가하였고 이후 60분까지는 비슷한 증가량(20㎍/㎕)을 나타내었다. RNA의 함량은 30℃에 비해 42℃실험군이 30분내에 약 3배의 증가를 나타내었고 60분에서는 15.3㎍/㎕로 30℃와 유사한 증가량을 나타냈다. 단백질의 전기영동으로 30℃와 42℃ 실험군에서 합성된 단백질의 양상을 비교해 보면 42℃실험군에서는 30분 이후부터 90 Kilodalton(KDa)의 새로운 단백질이 나타났다. RNase의 전기영동은 30℃와 42℃ 실험군에서 모두 2종류의 RNase 가 확인되었다. RNase 활성도의 변화를 보면 30℃실험군에서의 neutral RNaes는 기본반응액에 비해 60분까지 활성도가 1.5배 감소하였으며, 42℃실험군은 45분에 활성도가 0.3배 증가하였다. acid RNase인 경우 30℃실험군에서는 60분에 활성도가 4.4배 증가하였으며, 42℃ 실험군에서는 17배가 증가하였다. alkaline RNase인 경우 30℃실험군에서는 45분부터 활성도가 전혀 나타나지 않았으며 42℃실험군은 45분에 활성도가 3.4배 증가하였다. 따라서 3종류의 RNase 가 모두 30℃에 비해 42℃에서 활성도가 증가하며, 특히 alkaline, neutral RNase 의 활성도가 높은 것을 알 수 있었다. 이상의 결과로 보아 고온충격을 가했을 때 E. coli 는 온도 변화에 적응하기 위하여 HSP을 합성하였으며, 세포내 새로운 RNase의 유도는 일어나지 않았으나 RNase 활성도의 증가는 볼 수 있었다. The present study was designed to know the effects of heat-shock on metabolic process in E. coli. For this purpose, growth curve, protein and RNA contents were measured during heat shock. And Under the same condition, protein patterns were analized by SDS-PAGE. Also, the RNase activity was assayed as described by Josefsson(1962). When E. coli the grown at 30℃ was transferred to 42℃, the cell number increased about ??. The amount of total proteins increased about 4.5-fold within 5 min and RNA content increased gradually for 30 min after temperature-shifts but decreased thereafter. From SDS-PAGE of total proteins and RNase, it was detected that a new protein(90KDa) was induced from 30 min after temperature-shifts and two types RNase were synthesized in both 30℃ and 42℃ group. The RNase activity of 42℃ group increased more markedly than that of 30℃ group. In 42℃ group, the activity of neutral and alkaline RNase increased 0.3-fold and 4.5-fold from zero time to 45 min, respectively and that of acid RNase increased 17-fold from zero time to 60 min. The present results suggest that the relative content of macromolecules increases significantly when E. coli cells are grown by the treatment of heat and that the activity of RNase was increased.

중환자실 병원감염에 대한 다기관 공동 조사연구

박은숙,박미라,진혜영,김정은,최정실,송영구,최영화,이위교,홍성관,허애정,양동규,김준명 대한병원감염관리학회 2003 의료관련감염관리 Vol.8 No.1

「임원십육지(林園十六誌)」에 수록된 어패류의 향약성(鄕藥性)에 관한 연구

백숙은,최영진 동아시아식생활학회 2004 동아시아식생활학회지 Vol.14 No.3

This study was conducted to figure out the nutritional nature of seafoods categorized according to the medicinal effects and the usages introduced in Lim-Won-Sib-Rheuk-Ji, one of the well-known encyclopedias published during the Chosun Dynasty. They were compared with those introduced in other cooking books in order to find out how they were used in the diet of real-life. The seafoods of the book were first categorized into the fish 20, the mollusk 5. the crustacea 4, and the shellfish 7, and reptile according to the biological taxonomy, and then each one was reviewed in terms of the taste and the food-nature. Generally, the fishes has the sweet taste; the crustacea and the shellfish the salty or sour in addition to the sweet taste; none of them were bitter or hot. Most of them had the mild nature; seven of them were regarded as warm; four as cool; one as cold from the standpoint of the traditional medicine. The food-nature of seafoods was closely related with the medicinal effects on the human body. These seafoods were characteristically used in daily dietary life as well as the medical applications; used as the side-dishes rather than the main-dishes. The cooking methods of boiling, steaming, and baking were preferred to drying and stewing. The preservation methods favored were the fermentation, drying and salting. These cooking and preservation methods were believed to reflect the nature of the seafoods to manifest the medicinal effects.