간호대생들의 임상실습 스트레스, 학업적 자기효능감 및 진로정체감에 대한 연구

최유빈,최민지,이은형,이연우,우소연,하희주,허예지,박수현,허미래,이가현 이화여자대학교 간호과학대학 2015 이화간호학회지 Vol.- No.49

Purpose: The purpose of this study was to investigate clinical practice stress, academic self-efficacy, and career identity among undergraduate students in nursing practicum. Method: This study was a descriptive correlational design using the survey method. The study included 267 undergraduate students attending to 5 college in Seoul. The data was gathered from August 2014 to October 2014 and the data were analyzed using IBM SPSS statistics version 22.0 Program with descriptive statistics, t-test, analysis of variance with Scheffe test, and Pearson’s correlation coefficient. Results: Situational characteristics of Clinical Practice Stress(CPP) was significantly different with regards to task difficulties and efficacy self-confidence of academic self-efficacy(ASE) (r= .179, p= .003; r= .166, p= .006). Statistically significant positive relationship was founded between Personal characteristics of CPP and self-confidence of ASE (r= .239, p< .01). External regulators of CPP was significantly different according to self-confidence and task difficulties (r= .175, p= .003; r= .132, p= .028). The self-confidence and efficacy for self-confidence of ASE were a significantly correlated with Career Identity; The Career identity also was a significantly correlated with all sub-categories of CSS scale(r= -0.208, p< 0.01; r= -0.369, p< 0.01; r= -0.153, p< .011) Conclusion: This study showed positive statistical relationships associated with clinical practice stress, academic self-efficacy, and career identity as a preliminary evidence-based study for guiding education in nursing curriculum. Further research should be need for students’ future as a professional nurse.

견(絹) Fibroin의 효소분해(酵素分解)에 관(關)한 연구(硏究) (2) -견층부위별(繭層部位別) Fibroin 분해율(分解率) 차이(差異)와 견사물성과(繭絲物性)과의 관계(關係)-

이용우 ( Y. W. Lee ),최병희 ( B. H. Choe ),송기언 ( K. E. Song ),남중희 ( J. H. Nahm ) 한국잠사학회 1976 한국잠사곤충학회지 Vol.18 No.1

각종 고치의 견층부위별 fibroin 효소분해율의 차이 및 견사물성과의 관계를 구명코자 시험하여 다음과 같은 결과를 얻었다. 1. 각종 고치의 견층부위별 fibroin 효소분해율은 외층에서 내층으로 갈수록 높았다. 2. 이상용견의 견층부위별 fibroin 분해율은 정상견에 비하여 높았으며 옥견>박피견>사용견>정견의 순위를 보이었다. 3. 원종인 잠111과 잠112의 fibroin 분해율 및 sericin 함유량은 교유종인 잠 111×잠112보다 높았다. 4. 인공사료육잠견의 견층부위별 fibroin의 분해율은 외층보다 내층으로 갈수록 증가되었으며 sericin 함유량은 외층에서 내층으로 갈수록 감소되었으나 최내층에서 약간 증가되는 경향을 보이었다. 5. 견층부위별 연편사의 절단강력은 외층에서 내층으로 갈수록 감소되는 경향이었고 이상용견의 절단강역은 정견에 비하여 저하되었다. 6. 견층부위별 fibroin 분해율과 견사의 절단강력과는 부의 상관(r=-0.8)이 인정되고 그 회귀방정식은 y=-0.29x+5.07이었다. The study was carried out to investigate the variations in the fibroin hydrolysis of different cocoon shell layers, and the relationship between the hydrolysis and silk physical property. The obtained results are as follows: 1. The fibroin hydrolyzing ratio was highest at the inner layer of cocoon shell and, next in order, at the middle layer and at the outer layer. 2. The fibroin hydrolyzing ratio of abnormal cocoons was higher than normal cocoon and it was different among them, tile highest was double cocoon, thin shell cocoon and perforated cocoon in order. 3. The sericin content and fibroin hydrolyzing ratio of Jam 111 and Jam 112 was higher than that of Jam 111×Jam 112. 4. The fibroin hydroiyzing ratio of the cocoons fed with the artificial diets was increased at the inner layer. The sericin content of those lessened at the inner layer, however, it slightly increased at the most inner layer more than at the inner layer. 5. The breaking strength of the degummed silk fiber of different cocoon layers was reduced at the inner layer. The breaking strength of abnormal silk fiber was less than that of normal silk fiber. 6. A negative correlation (r=-0.8) was approved between fibroin hydrolyzing ratio and breaking strength of silk fiber, and the regression line was Y=-0.29x+5.07.

Effects of β-Glucan on the Release of Nitric Oxide by Macrophages Stimulated with Lipopolysaccharide

Choi, E.Y.,Lee, S.S.,Hyeon, J.Y.,Choe, S.H.,Keum, B.R.,Lim, J.M.,Park, D.C.,Choi, I.S.,Cho, K.K. Asian Australasian Association of Animal Productio 2016 Animal Bioscience Vol.29 No.11

This research analyzed the effect of ${\beta}$-glucan that is expected to alleviate the production of the inflammatory mediator in macrophagocytes, which are processed by the lipopolysaccharide (LPS) of Escherichia. The incubated layer was used for a nitric oxide (NO) analysis. The DNA-binding activation of the small unit of nuclear factor-${\kappa}B$ was measured using the enzyme-linked immunosorbent assay-based kit. In the RAW264.7 cells that were vitalized by Escherichia coli (E. coli) LPS, the ${\beta}$-glucan inhibited both the combatant and rendering phases of the inducible NO synthase (iNOS)-derived NO. ${\beta}$-Glucan increased the expression of the heme oxygenase-1 (HO-1) in the cells that were stimulated by E. coli LPS, and the HO-1 activation was inhibited by the tin protoporphyrin IX (SnPP). This shows that the NO production induced by LPS is related to the inhibition effect of ${\beta}$-glucan. The phosphorylation of c-Jun N-terminal kinases (JNK) and the p38 induced by the LPS were not influenced by the ${\beta}$-glucan, and the inhibitory ${\kappa}B-{\alpha}$ ($I{\kappa}B-{\alpha}$) decomposition was not influenced either. Instead, ${\beta}$-glucan remarkably inhibited the phosphorylation of the signal transducer and activator of transcription-1 (STAT1) that was induced by the E. coli LPS. Overall, the ${\beta}$-glucan inhibited the production of NO in macrophagocytes that was vitalized by the E. coli LPS through the HO-1 induction and the STAT1 pathways inhibition in this research. As the host immune response control by ${\beta}$-glucan weakens the progress of the inflammatory disease, ${\beta}$-glucan can be used as an effective immunomodulator.

Molecular investigation of tick-borne pathogens in ticks from grazing cattle in Korea

Kang, S.W.,Doan, H.T.T.,Choe, S.E.,Noh, J.H.,Yoo, M.S.,Reddy, K.E.,Kim, Y.H.,Kweon, C.H.,Jung, S.C.,Chang, K.Y. Elsevier 2013 Parasitology international Vol.62 No.3

This study was carried out to identify the tick species that infest grazing cattle and to determine the presence of tick-borne pathogens transmitted by these ticks in Korea. A total of 903 ticks (categorized into 566 tick pools) were collected from five provinces during 2010-2011. The most prevalent tick species was Haemaphysalis longicornis, followed by three Ixodes spp. ticks. The collected ticks were infected with both rickettsial and protozoan pathogens. In all, 469 (82.9%) tick pools tested positive for the Anaplasma/Ehrlichia 16S rRNA gene, whereas 67 (11.8%) were positive for the Babesia/Theileria 18S rRNA gene. Among the rickettsial pathogens, E. canis was detected with the highest rate (22.3%), followed by A. platys (20%), E. chaffeensis (19.4%), E. ewingii (19.3%), Rickettsia sp. (12.4%), A. phagocytophilum (5.5%) and E. muris (0.5%). Among the protozoan pathogens, T. equi was detected with the highest rate (7.2%), followed by T. sergenti/T. buffeli (3.7%) and B. caballi (0.35%). Simultaneous infections with up to seven pathogens were also identified. In particular, ticks infected with rickettsial pathogens were also infected with protozoan pathogens (22 samples). All five provinces investigated infected with tick-borne pathogens.

견(絹) Fibroin의 효소분해(酵素分解)에 관(關)한 연구(硏究) (3) -가잠(家蠶)의 원종(原種) 및 교잡종견사(交雜種繭絲)의 Fibroin 분해율(分解率) 차이(差異)-

이용우 ( Y. W. Lee ),최병희 ( B. H. Choe ),송기언 ( K. E. Song ),남중희 ( J. H. Nahm ) 한국잠사학회 1976 한국잠사곤충학회지 Vol.18 No.2

우리나라 장려잠품종의 원종과 교잡종견의 fibroin 분해율 및 각종 특수품종견에 대한 fibroin 분해율과 견사형태와의 관계를 구명코저 시험하여 다음 결과를 얻었다. 1. 원종과 교잡종독의 fbroin 효소분해에 있어서 원종은 F1 교잡종에 비하여 분해율이 높았다. 2. 양 원종의 평균 fbroin 분해율은 그 교잡종의 분해율과 정상관(r=+0.86)이 있었고 그 회귀방정식은 y=0.81x+0.04이다. 3. 교잡종견사 fibroin의 분해율에 있어서 잠103×잠104가 다른 장훈품종에 비하여 분해율이 낮았다. 4. 각종 특수품종 견사의 fibroin 분해에 있어서 품종간에 분해율차이가 인정되었고 견사섬도와 fibroin 분해율과는 낮은 정상관(r=0.6)이 있었다. 5. 이상의 결과에서 견 fibroin 분해율은 유전적 성질을 가지므로 잠품종육종에 있어서 이와 관련된 실용형질 선발에 marker로서 이용될 수 있을 것으로 사료된다. The study was carried out to investigate the variations in the fibroin hydrolysis of leading silkworm varieties in Korea, and the relationship between the fibroin hydrolysis of the silkworm varieties with some characteristics and silk morphological property. The results obtained are summarized as follows: 1) The fibroin hydrolyzing ratio of both parent silkworm cocoons was reduced in the F1 hybrids. 2) A positive corelation (r=+0.86) was approved between the mid-parent value and the F1 hybrid in the fibroin hydrolysis. 3) It was disclosed that the fibroin hydrolyzing ratio of Jam 103×Jam 104 was the lowest among the leading silkworm F1 hybrids. 4) The fibroin hydrolysis was affected by the silk morphological property, showing a positive corelation between the size of cocoon filament and the fibroin hydrolyzing ratio. 5) It was thought that the determination of the fibroin hydrolyzing ratio was useful as a marker for the selection of its related economical characters in silkworm breeding, because the fibroin hydrolysis of parents silkworm cocoons was heritable in their F1 hybrids.

장티프스에서 효소면역측정법의 진단적 가치

차창용,김윤원,황응수,정문현,오명돈,최강원 대한감염학회 1985 감염 Vol.17 No.2

The diagnostic value of ELISA for typhoid fever was tested with 43 sera from patients with enteric fever and 27 sera from patient who had no known history of enteric fever. IgG antibody was most commonly elevated (in 97.6%), followed by IgA (in 38.3%) and IgM antibody (in 65.1%). On the other hand, IgM and IgA antibody were found to be elevated in 40.7% of various infectious (notably due to M, tbc and gram negative enteric bacteria) and noninfectious conditions. On the contrary, IgG antibody was elevated only occasionally. (7.4%). IgG antibody was most sensitive and specific indicator for the S. typhi and S. paratyphi A infection.

토끼의 위장관 점막에 출현하는 장크롬친화세포에 대한 형태학적 연구

김문자,유진영,윤은경,최신영,홍영미 이화여자대학교 의과대학 1977 梨花醫學誌 Vol.- No.9

The distribution, type and staining characteristics of the enterochromaffin cells in the epithelia of the gastrointestinal tract of the rabbits were observed by light microscopy. 1. The number of the EC cells in the 3.5mm breadth of the mucosa was most numerous in the region of duodenal papilla (133.2±30.4 (41.5%)), 76.6±20.6 (24.8%) in the stomach body, 50.0±18.8 (15.5%) in the jejunum, 32.8±12.6 (10.5%) in the ascending colon and 21.6±9.6 (6.9%) in the near portion of the duodenal papilla. 2. The cells in the stomach body were mostly oval or cylindrical. The cells in the villi of the duodenum, duodenal papilla and jejum were tall cylindrical or spindle in shape but were low cylindrical or spindle in the glands of that region. The EC cells in the colon were tall cylindrical or spindle on the surface of the epitheluim and low cylindrical in the glands. 3. The EC cells were appeared in yellowish-orange by Hematoxylin-eosin stain and the secretory granules in the cytoplasm if the EC cells after chromication were brownish black by Masson-Hamperl's silver staining.

한국인 CCR5 유전자에서의 돌연변이 빈도

오명돈,김성순,김은영,이선희,김남정,박근용,김유석,김소마,김태규,최강원,이주실 국립보건연구원 2000 국립보건원보 Vol.37 No.-

한국에서 유행하는 �냑鵝뵉퓌竄叢�관한 혈청역학적 연구

오대규,심재철,백승복,최강원,정의범,정태화,장우현,윤형희,오희복 대한감염학회 1987 감염 Vol.19 No.4

A seroepidemiological survey was performed to estimate the prevalence of leptospirosis in Korean population. The study population consisted of 967 randomly selected people from 17 counties out of 5 provinces. Macroscopic slide agglutination test was used for serology of leptospirosis. 117 sera out of 967 were positive (11.7%) for leptospirosis. Kang Won Province showed highest positive rate (17.1%), followed by Kyunggi (16.2%), Chung Book (10.2%), Kyung Book (6.2%), Chun Nam Province (2.2%), Hoeng Sung County showed highest prevalence rate (26.2%) and Chang Sung County Showed lowest prevalence (0%). There was no difference in prevalence rate between male and female. But older people (41∼60 years) showed higher prevalence rate than the younger people (21∼30 years). Some activities, including weeding in the field or grave and working barefoot in the rice field were associated with higher prevalence. History of recent flu-like symptoms suggestive of leptospirosis (chill, headache, cough, walking difficulty, dyspnea, diarrhea, conjunctival suffusion) was more common in antibody positive group. Leptospirosis is wide spread infection throughout Korea, though considerable variance in prevalence rate was noted.

Analysis of the complete genome sequence of two Korean sacbrood viruses in the Honey bee, Apis mellifera

Choe, S.E.,Nguyen, L.T.K.,Noh, J.H.,Kweon, C.H.,Reddy, K.E.,Koh, H.B.,Chang, K.Y.,Kang, S.W. Academic Press 2012 Virology Vol.432 No.1

The complete genomic RNAs of two Korean sacbrood virus (SBV) strains, which infect the honey bee, Apis mellifera, were sequenced. The two sequences (AmSBV-Kor19, AmSBV-Kor21) were distinguished by the presence or absence of a PstI restriction site. These strains comprised of 8784bp and 8835bp; contained a single large ORF (179-8707 and 179-8758) encoding 2843 and 2860 amino acids, respectively. Deduced amino acid sequences comparison with some insect viruses showed that regions of helicase, protease and RdRp domains; structural genes were located at the 5' end and non-structural genes at the 3' end. Multiple sequence alignment showed that AmSBV-Kor19 was missing a section between nucleotides 2311 and 2361 (present in SBV-UK and CSBV) but was similar to that of the Korean SBV strain that infects A. cerana (AcSBV-Kor). The differences in the AmSBV-Kor19 strain may be the result of the virus adapting to a different host.