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Actuator Fault Detection for Discrete-time Switched Linear Systems with Output Disturbance
Dongsheng Du,Shengyuan Xu 제어·로봇·시스템학회 2017 International Journal of Control, Automation, and Vol.15 No.6
In this paper, the problem of actuator fault detection for discrete-time switched systems with outputdisturbance is investigated. By using the descriptor observer method, an H∞ fault detection filter is designed toguarantee that the augmented system is admissible and satisfies a prescribed H∞ performance index. By utilizingswitched Lyapunov function approach, a sufficient condition for the admissible of the augmented system is obtained. Based on the obtained results, a desired fault detection filter can be designed. All the results are formulated in theform of linear matrix inequalities. Finally, an example is proposed to illustrate the effectiveness of the developedmethod.
Dongsheng Wu,Yuanjian Wu,Liuhong Wang,Weidong Xu,Qiao Zhong 대한진단검사의학회 2014 Annals of Laboratory Medicine Vol.34 No.1
Background: The dramatic increase in use of the IgG test for toxoplasma, rubella, cyto- megalovirus (CMV), and herpes simplex virus (HSV) [TORCH] has led to the requirement for a high-efficiency method that can be used in the clinical laboratory. This study aimed to compare the results of BGI-Array ELISA TORCH IgG (BGI-GBI, China) screening method to those of Virion/Serion TORCH IgG ELISA (Virion/Serion, Germany). Methods: Serum specimens (n=400) submitted for routine IgG testing by Virion/Serion ELISA were also tested using the BGI-Array ELISA method. The agreements of these two kinds of method were analyzed by κ-coefficients calculation. Results: Following repeat testing, the BGI-Array ELISA TORCH IgG assays demonstrated agreements of 99.5% (398/400 specimens), 98% (392/400 specimens), 99% (396/400 specimens), and 99.5% (398/400 specimens), respectively. The BGI-Array ELISA IgG as- says provided results comparable to Virion/Serion ELISA results, with κ-coefficients show- ing near-perfect agreement for the HSV (κ=0.87), rubella (κ=0.92) and CMV (κ=0.93) and substantial agreement for the toxoplasma (κ=0.80) IgG assays. The use of the BGI- Array ELISA TORCH IgG assays could reduce the turnaround time (1.5 hr vs. 5 hr by Vi- rion/Serion ELISA for 100 specimens) and were easy to use. Conclusions: BGI-Array ELISA TORCH IgG shows a good agreement with Virion/Serion ELISA methods and is suitable for clinical application.
Tang, Dongsheng,Wan, Jiahui,Xu, Xiaopeng,Lee, Young Woong,Woo, Han Young,Feng, Kui,Peng, Qiang Elsevier 2018 Nano energy Vol.53 No.-
<P><B>Abstract</B></P> <P>In this work, two wide bandgap polymers of PDTT-TZNT and PDTF-TZNT were developed by Stille-coupling of naphtho[1,2-c:5,6-c]bis(2-octyl-[1,2,3]triazole) (TZNT) acceptor unit with bithiophene (DTH) and fluorinated bithiophene (DTF), respectively. These polymers exhibited a wide bandgap over 1.84 eV. The fluorinated PDTF-TZNT had lower highest occupied molecular orbital HOMO level (− 5.24 eV), higher molar absorption coefficient (1.28 × 10<SUP>5</SUP> M<SUP>−1</SUP> cm<SUP>−1</SUP>), and higher molecular packing order. Using a low bandgap 3,9-bis(2-methylene-(5&6-methyl-(3-(1,1-dicyanomethylene)-indanone)))−5,5,11,11-tetrakis(4-hexylphenyl)-dithieno[2,3-d:2′,3′-d′]-s-indaceno[1,2-b:5,6-b′]-dithiophene (IT-M) as the electron acceptor, the PDTF-TZNT:IT-M devices generated a higher power conversion efficiency (PCE) of 10.05%. To make up the weak absorption of above binary blend of PDTF-TZNT:IT-M in the short wavelength region and increase the device performance further, a large bandgap small molecular acceptor of 5,5,10,10,15,15-hexabutyl-2,7,12-tri(4-(3-ethylhexyl-4-oxothiazolidine-2-yl)dimalononitrile-benzothiadiazole)-truxene (meta-TrBRCN) was added as the second acceptor material to fabricate ternary blend PSCs. The meta-TrBRCN could not only expand the absorption range but also fine-tune the blend morphology by stepwise changing its content. When 0.2 of meta-TrBRCN was added, the PCE of PDTF-TZNT:IT-M devices was improved to 11.48%.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Two novel naphthobistriazole-based wide bandgap donor polymers were successfully synthesized and characterized. </LI> <LI> The introduced fluorine atoms enabled the PDTF-TZNT:IT-M devices to obtain a higher PCE of 10.05%. </LI> <LI> The ternary blend strategy boosted the PCE up to 11.48% in the PDTF-TZNT<SUB>x</SUB>:IT-M<SUB>y</SUB>:meta-TrBRCN<SUB>z</SUB> devices. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>Two novel naphthobistriazole-based wide bandgap polymers, PDTH-TZNT and PDTF-TZNT, has been developed for non-fullerene polymer solar cells. The fluorinated PDTF-TZNT exhibited a higher PCE of 10.05% in binary PDTT-FTAZ:IT-M devices. By adding 0.2 of meta-TrBRCN as the second acceptor, the related ternary blend devices exhibited a significantly improved PCE of 11.48%.</P> <P>[DISPLAY OMISSION]</P>
An Efficient Replicated System for the Metadata of HDFS
Zhanye Wang,Tao Xu,Dongsheng Wang 보안공학연구지원센터 2016 International Journal of Grid and Distributed Comp Vol.9 No.5
Hadoop HDFS is an open source project from Apache Software Foundation for scalable, distributed computing and data storage. HDFS has become a critical component in today's cloud computing environment and a wide range of applications built on top of it. However, the initial design of HDFS has introduced a single-point-of-failure, since HDFS contains only one active namenode, if this namenode experiences software or hardware failures, the whole HDFS cluster is unusable, this is a reason why people are reluctant to deploy HDFS for an application whose requirement is high availability. In this paper, we present a solution to enable the high availability for HDFS's namenode through efficient metadata replication. Our solution has 3 major advantages than existing ones: We utilize multiple active namenodes, instead of one, to build a cluster to serve requests of metadata simultaneously; We implement a pub/sub system to handle the metadata replication process across these active namonodes efficiently; We also propose a novel replication algorithm to deal with the network delay when the namonodes are deployed in different areas. Based on the solution we build a prototype called NCluster and integrate it with HDFS. We evaluate NCluster to exhibit its feasibility and effectiveness. The experimental results show that our solution performs well with low replication cost, good throughput and scalability.
Lianzhou Yang,Yuchen Cai,Dongsheng Zhang,Jian Sun,Chenyu Xu,Wenli Zhao,Wenqi Jiang,Chunhua Pan 한국유방암학회 2018 Journal of breast cancer Vol.21 No.4
Purpose: Immune suppression is common in patients with advanced breast cancer but the mechanisms underlying this phenomenon have not been sufficiently studied. In this study, we aimed to identify B7 family members that were able to predict the immune status of patients, and which may serve as potential targets for the treatment of breast cancer. We also aimed to identify microRNAs that may regulate the expression of B7 family members. Methods: The Cancer Genome Atlas data from 1,092 patients with breast cancer, including gene expression, microRNA expression and survival data, were used for statistical and survival analyses. Polymerase chain reaction and Western blot were used to measure messenger RNA and protein expression, respectively. Luciferase assay was used to investigate direct microRNA target. Results: Bioinformatic analysis predicted that microRNA (miR)-93, miR-195, miR-497, and miR-340 are potential regulators of the immune evasion of breast cancer cells, and that they exert this function by targeting CD274, PDCD1LG2, and NCR3LG1. We chose CD274 for further investigations. We found that miR-195, miR-497, and CD274 expression levels were inversely correlated in MDA-MB-231 cells, and miR-195 and miR-497 expressions mimic inhibited CD274 expression in vitro. Mechanistic investigations demonstrated that miR-195 and miR-497 directly target CD274 3´ untranslated region. Conclusion: Our data indicated that the level of B7 family members can predict the prognosis of breast cancer patients, and miR-195/miR-497 regulate CD274 expression in triple negative breast cancer. This regulation may further influence tumor progression and the immune tolerance mechanism in breast cancer and may be able to predict the effect of immunotherapy on patients.
( Yuepeng Song ),( Miaomiao Chen ),( Baoyan Xu ),( Dongsheng Gao ),( Jing Guo ),( Lingfeng Xu ),( Zheng Wang ),( Hyoung Seop Kim ) 대한금속재료학회(구 대한금속학회) 2016 대한금속·재료학회지 Vol.54 No.11
Herein, we report the results of our investigation on the effect of friction and anvil design on the heterogeneous plastic-deformation characteristics of copper during the compressive stage of high-pressure torsion (HPT), using the finite element method. The results indicate that the friction and anvil geometry play important roles in the homogeneity of the deformation. These variables affect the heterogeneous level of strain in the HPT compressed disks, as well as the flash in the disk edge region. The heterogeneous plastic deformation of the disks becomes more severe with the increasing depth of the cavity, as anvil angle and friction coefficient increase. However, the homogeneity increases with increases in the wall angle. The length of flash and the area of the dead metal zone increase with the depth of the cavity, while they decrease at a wall angle of 180°. (Received March 17, 2016; Accepted May 25, 2016)
Inhomogeneous Deformation of Interstitial Free Steel during the High Pressure Torsion Process
Yuepeng Song,Miaomiao Chen,Wenke Wang,Baoyan Xu,Dongsheng Gao,Shuai Zhang,Hyoung Seop Kim 대한금속ㆍ재료학회 2017 대한금속·재료학회지 Vol.55 No.10
Interstitial free (IF) steel disks were subjected to various degrees of revolution during application of the high-pressure torsion (HPT) process, and the resulting distributions of hardness and microstructure during the early torsion stage of high-pressure torsion (HPT) were investigated using experimental and simulation approaches. The results indicated that the deformation in the HPT-processed IF steel disk was inhomogeneous, producing low hardness in the center and high hardness in the edge region. The experimental results, including the hardness and microstructure distributions, indicated that the severe deformation zone proceeds gradually from the center to the edge of the HPT disks in the early torsion stage, and also confirmed verify that the deformation on the upper surface of the disks lags behind that on the bottom surface. Simulation results from a finite element method analysis strongly supported the experimental conclusions. (Received December 30, 2016; Accepted July 2, 2017)
Parallel Gene Loss and Acquisition Among Strains of Different Brucella Species and Biovars
Zhijun Zhong,Yufei Wang,Jie Xu,Yanfen Chen,Yuehua Ke,Xiaoyan Zhou,Xitong Yuan,Dongsheng Zhou,Yi Yang,Ruifu Yang,Guangneng Peng,Hai Jiang,Jing Yuan,Hongbin Song,Buyun Cui,Liuyu Huang,Zeliang Chen 한국미생물학회 2012 The journal of microbiology Vol.50 No.4
The genus Brucella is divided into six species; of these, B. melitensis and B. abortus are pathogenic to humans, and B. ovis and B. neotomae are nonpathogenic to humans. The definition of gene loss and acquisition is essential for understanding Brucella’s ecology, evolutionary history, and host relationships. A DNA microarray containing unique genes of B. melitensis Type strain 16MT and B. abortus 9-941 was constructed and used to determine the gene contents of the representative strains of Brucella. Phylogenetic relationships were inferred from sequences of housekeeping genes. Gene loss and acquisition of different Brucella species were inferred. A total of 214 genes were found to be differentially distributed,and 173 of them were clustered into 15 genomic islands (GIs). Evidence of horizontal gene transfer was observed for 10GIs. Phylogenetic analysis indicated that the 19 strains formed five clades, and some of the GIs had been lost or acquired independently among the different lineages. The derivation of Brucella lineages is concomitant with the parallel loss or acquisition of GIs, indicating a complex interaction between various Brucella species and hosts.