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- 저자 : Dongsheng Yu (검색결과 16 건)
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Dongsheng Lv,Meirong Zhao,Lixia Chen,Dongsheng Yu,Xiaobin Yun,Qing Yang,Xiaojun Huang 대한신경정신의학회 2017 PSYCHIATRY INVESTIGATION Vol.14 No.3
Objective: The aim of this study was to investigate ziprasidone plasma concentration, daily dose and clinical efficacy and safety in Han Chinese and Mongolian patients with first-episode schizophrenia. Methods: A total of 123 inpatients affected by schizophrenia were recruited from the Mental Health Center of Inner Mongolia in China. Ziprasidone plasma concentration, clinical efficacy and side effects were systematically evaluated at baseline, and at 1, 2, 4, and 6 weeks. Metabolic measures such as changes in weight, body mass index (BMI), fasting blood glucose (FBG), triglycerides, and cholesterol, were also recorded. Results: 90 patients completed the study. Compared with Han patients, on average, Mongolian patients received a significantly higher ziprasidone dosage for adequate symptom control during the 6-week period and had a lower plasma concentration-to-dose ratio. The Mongolian patients also experienced greater increases in weight and BMI. No significant differences between the two ethnic groups were found in the rate of reduction in the Positive and Negative Syndrome Scale (PANSS) score, Treatment Emergent Symptom Scale (TESS) total score, FBG, triglycerides, cholesterol or Q-Tc interval. Conclusion: Compared to Han Chinese patients, Mongolian patients appeared to have increased ziprasidone clearance and require higher doses to achieve effective treatment for schizophrenia.
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Yu Liyang,Wang Dongsheng,Huang Ruimin,Cao Fei,Guo Chunlei,Zhang Jingzheng 한국식물생명공학회 2024 Plant biotechnology reports Vol.18 No.1
The B-box (BBX) proteins are a class of zinc finger transcription factors and play critical roles in plant development and growth. However, they have not been systematically characterized in Chinese chestnut (Castanea mollissima), an important nut with rich nutrition and high economic value. Here, 18 BBX genes were identified in Chinese chestnut genome and divided into five groups through phylogenetic analysis, with members in the same group containing the same conserved domain organization. The collinearity analysis showed that dispersed duplication played a major role in the expansion of CmBBX gene family inferred to have evolved through purifying selection. Transcriptome analysis and qRT-PCR experiments suggested that CmBBX genes showed different expression patterns in different Chinese chestnut tissues, and revealed some CmBBXs may have potential functions in the development of Chinese chestnut buds, nuts, fertile/abortive ovules. Combined with the analysis of conserved domain, motif, cis-elements, expression level and protein three-dimensional structure, the lack of cis- acting elements related to meristem expression and gibberellin-responsiveness may lead to the no-expression of CmBBX9 in Chinese chestnut. The systematic analysis of Chinese chestnut BBX genes provides a basis for further understanding the characteristics and potential functions of BBX gene family.
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Dual-Coupled Inductor High Gain DC/DC Converter with Ripple Absorption Circuit
Jie Yang,Dongsheng Yu,Mohammed Alkahtani,Ligen Yuan,Zhi Zhou,Hong Zhu,Maxwell Chiemeka 전력전자학회 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.6
High-gain DC/DC converters have become one of the key technologies for the grid-connected operation of new energy power generation, and its research provides a significant impetus for the rapid development of new energy power generation. Inspired by the transformer effect and the ripple-suppressed ability of a coupled inductor, a double-coupled inductor high gain DC/DC converter with a ripple absorption circuit is proposed in this paper. By integrating the diode-capacitor voltage multiplying unit into the quadratic Boost converter and assembling the independent inductor into the magnetic core of structure coupled inductors, the adjustable range of the voltage gain can be effectively extended and the limit on duty ratio can be avoided. In addition, the volume of the magnetic element can be reduced. Very small ripples of input current can be obtained by the ripple absorption circuit, which is composed of an auxiliary inductor and a capacitor. The leakage inductance loss can be recovered to the load in a switching period, and the switching-off voltage spikes caused by leakage inductance can be suppressed by absorption in the diode-capacitor voltage multiplying unit. On the basis of the theoretical analysis, the feasibility of the proposed converter is verified by test results obtained by simulations and an experimental prototype.
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Dual-Coupled Inductor High Gain DC/DC Converter with Ripple Absorption Circuit
Yang, Jie,Yu, Dongsheng,Alkahtani, Mohammed,Yuan, Ligen,Zhou, Zhi,Zhu, Hong,Chiemeka, Maxwell The Korean Institute of Power Electronics 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.6
High-gain DC/DC converters have become one of the key technologies for the grid-connected operation of new energy power generation, and its research provides a significant impetus for the rapid development of new energy power generation. Inspired by the transformer effect and the ripple-suppressed ability of a coupled inductor, a double-coupled inductor high gain DC/DC converter with a ripple absorption circuit is proposed in this paper. By integrating the diode-capacitor voltage multiplying unit into the quadratic Boost converter and assembling the independent inductor into the magnetic core of structure coupled inductors, the adjustable range of the voltage gain can be effectively extended and the limit on duty ratio can be avoided. In addition, the volume of the magnetic element can be reduced. Very small ripples of input current can be obtained by the ripple absorption circuit, which is composed of an auxiliary inductor and a capacitor. The leakage inductance loss can be recovered to the load in a switching period, and the switching-off voltage spikes caused by leakage inductance can be suppressed by absorption in the diode-capacitor voltage multiplying unit. On the basis of the theoretical analysis, the feasibility of the proposed converter is verified by test results obtained by simulations and an experimental prototype.
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Jianlong Yin,Jing Yu,Cheng Lou,Dongsheng Li,Xiaoyan Shen,Ming Li 한국정밀공학회 2023 International Journal of Precision Engineering and Vol.24 No.2
In an aerostatic restrictor, the presence of friction between the high-pressure air and the aerostatic restrictor wall can lead to non-uniform pressure and temperature distributions of the lubricating air film, which will affect the aerostatic restrictor performance. Therefore, explicating the pressure and temperature distributions of the lubricating air film could help to improve the characteristics and performance of the aerostatic restrictor. In this study, a theoretical model is established for the pressure and temperature distributions in the aerostatic restrictor with double U-shaped pressure-equalizing grooves, which is then compared with simulations, and finally verified by experiments. The results indicate the following. (1) The parameter distributions of the aerostatic restrictor’s air film are affected by the pressure-equalizing grooves and the orifice. (2) The air film parameter distributions are affected by the air source pressure and air film thickness. (3) The air film parameter distribution characteristics obtained from theoretical calculations, simulations, and experiments are consistent, indicating that the theoretical model is effective for studying the flow field of lubricating air film in the aerostatic restrictor. This model can also provide a theoretical basis for designing the orifice and pressure-equalizing grooves of the aerostatic restrictor, as well as selecting the air source pressure and air film thickness.
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Complex dental anomalies in a belatedly diagnosed cleidocranial dysplasia patient
Lu, Hui,Zeng, Binghui,Yu, Dongsheng,Jing, Xiangyi,Hu, Bin,Zhao, Wei,Wang, Yiming Korean Academy of Oral and Maxillofacial Radiology 2015 Imaging Science in Dentistry Vol.46 No.1
Cleidocranial dysplasia (CCD) is a rare congenital disorder, typically characterized by persistently open skull sutures, aplastic or hypoplastic clavicles, and supernumerary teeth. Mutations in the gene encoding the runt-related transcription factor 2 (RUNX2) protein are responsible for approximately two thirds of CCD patients. We report a 20-year-old CCD patient presenting not only with typical skeletal changes, but also complex dental anomalies. A previously undiagnosed odontoma, 14 supernumerary teeth, a cystic lesion, and previously unreported fused primary teeth were discovered on cone-beam computed tomography (CBCT) scans. Mutation analysis identified the causal c.578G>A (p.R193Q) mutation in the RUNX2 gene. At 20 years of age, the patient had already missed the optimal period for dental intervention. This report describes the complex dental anomalies in a belatedly diagnosed CCD patient, and emphasizes the significance of CBCT assessment for the detection of dental anomalies and the importance of early treatment to achieve good outcomes.
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Complex dental anomalies in a belatedly diagnosed cleidocranial dysplasia patient
Hui Lu,Binghui Zeng,Dongsheng Yu,Xiangyi Jing,Bin Hu,Wei Zhao,Yiming Wang 대한영상치의학회 2015 Imaging Science in Dentistry Vol.45 No.3
Cleidocranial dysplasia (CCD) is a rare congenital disorder, typically characterized by persistently open skull sutures, aplastic or hypoplastic clavicles, and supernumerary teeth. Mutations in the gene encoding the runt-related transcription factor 2 (RUNX2) protein are responsible for approximately two thirds of CCD patients. We report a 20-year-old CCD patient presenting not only with typical skeletal changes, but also complex dental anomalies. A previously undiagnosed odontoma, 14 supernumerary teeth, a cystic lesion, and previously unreported fused primary teeth were discovered on cone-beam computed tomography (CBCT) scans. Mutation analysis identified the causal c.578G>A (p.R193Q) mutation in the RUNX2 gene. At 20 years of age, the patient had already missed the optimal period for dental intervention. This report describes the complex dental anomalies in a belatedly diagnosed CCD patient, and emphasizes the significance of CBCT assessment for the detection of dental anomalies and the importance of early treatment to achieve good outcomes.
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Development of monocular video deflectometer based on inclination sensors
Shuo Wang,Shuiqiang Zhang,Xiaodong Li,Yu Zou,Dongsheng Zhang 국제구조공학회 2019 Smart Structures and Systems, An International Jou Vol.24 No.5
The video deflectometer based on digital image correlation is a non-contacting optical measurement method which has become a useful tool for characterization of the vertical deflections of large structures. In this study, a novel imaging model has been established which considers the variations of pitch angles in the full image. The new model allows deflection measurement at a wide working distance with high accuracy. A monocular video deflectometer has been accordingly developed with an inclination sensor, which facilitates dynamic determination of the orientations and rotation of the optical axis of the camera. This layout has advantages over the video deflectometers based on theodolites with respect to convenience. Experiments have been presented to show the accuracy of the new imaging model and the performance of the monocular video deflectometer in outdoor applications. Finally, this equipment has been applied to the measurement of the vertical deflection of Yingwuzhou Yangtze River Bridge in real time at a distance of hundreds of meters. The results show good agreement with the embedded GPS outputs.
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