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The etiology of potential small-bowel bleeding depending on patient’s age and gender
Song, Joo Hye,Hong, Sung Noh,Kyung Chang, Dong,Ran Jeon, Seong,Kim, Jin-Oh,Kim, Jinsu,Lee, Bo-In,Choi, Myung-Gyu,Kim, Kyeong Ok,Yang, Dong-Hoon,Song, Hyun Joo,Hyuk Do, Jae,Jeong Lim, Yun,Shim, Ki-Nam SAGE Publications 2018 United European gastroenterology journal Vol.6 No.8
<B>Background</B><P> Whether the etiology of potential small-bowel bleeding depends on the age and gender of the patient is not yet fully understood. </P><B>Methods</B><P> A total of 1953 patients who underwent video capsule endoscopy (VCE) to evaluate potential small-bowel bleeding and were registered in the Capsule Endoscopy Nationwide Database Registry from 2003 to 2014 were eligible for this study. VCE findings and the etiology of small-bowel bleeding were analyzed by age and gender. </P><B>Results</B><P> The diagnostic yield of VCE was 48.4% (95% CI: 46.2%-50.6%) and the diagnosis rate of etiology of potential small-bowel bleeding was 61.4% (95% CI: 59.2%-63.6%). The etiology of potential small-bowel bleeding depends on the age and gender of the patient. Crohn's disease and small-bowel diverticular diseases were more prevalent etiology of potential small-bowel bleeding in the young adults group (@@<@@ 40 years) whereas angiodysplasia was revealed to be a most common etiology in elderly group (≥ 60 years), reaching statistical significance ( p@@<@@0.00152) by Bonferroni correction. </P><B>Conclusions</B><P> The etiology of potential small-bowel bleeding depends on the age of the patient. Thus, an individualized lesion-specific diagnostic approach based on age might be needed for patients with potential small-bowel bleeding. </P>
( Ran Kim ),( Hee Seung Kim ),( Ki Dong Kim ),( Jae Hong No ),( Hyun Hoon Chung ),( Yong Beom Kim ),( Jae Weon Kim ),( Noh Hyun Park ),( Yong Sang Song ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.99 No.-
Endometriosis is known as a risk factor for epithelial ovarian cancer (EOC). Especially, it is associated with specific histology such as clear cell carcinoma of the ovary (CCC). However, the impact of endometriosis on prognosis of CCC is not clear. Thus, we investigated whether endometriosis may affect prognosis of CCC. We reviewed a database of 85 patients with CCC from August 1991 to July 2011, and evaluated whether endometriosis affected progression- free survival (PFS) and overall survival (OS). Furthermore, we searched an electronic search to identify relevant studies publied between 1990 and 2012, and performed a meta-analysis using 5 relevant studies. CCC with endometriosis was associated with young age (mean value; 52.6 vs. 59.4 years; p<0.01), early-stage disease (stage I-II disease; 71.8% vs. 45.7%; p=0.02) and high probability of optimal cytoreduction when compared with CCC alone (94.9% vs. 76.1%; p=0.03). There were no differences in PFS and OS between CCC with ES and CCC alone (mean values of PFS and OS; 126.2 vs. 138.7 months, and 148 vs. 173.1 months; p>0.05). Moreover, favorable prognostic factors were early-stage disease and optimal cytoreduction for PFS (adjusted hazard ratios [HRs], 0.18 and 0.19; 95% CIs, 0.06-0.52 and 0.07-0.53), and for OS (adjusted HRs, 0.19 and 0.20; 95% CIs, 0.05-0.69 and 0.06-0.72). In the meta-analysis, endometriosis did not affect PFS and OS (HRs, 1.03 and 0.83; 95% CIs, 0.57-1.88 and 0.52-1.34), and subgroup analyses based on histology and adjustment for age, extend of disease, optimal cytoreduction and platinum-based chemotherapy showed similar results. These findings suggest that endometriosis may not affect prognosis of CCC.
Dong Churl Kim,O-Kyun Kown,Hyun-Soo Kim,Byung-Seok Choi,Ki Soo Kim,Mi-Ran Park,Ki-Hong Yoon,Seung-Hyun Cho,Sang-Soo Lee,Jong Woong Hyun,Dae-Kon Oh,Min-Ho Song,Jeong Soo Kim IEEE 2010 IEEE photonics technology letters Vol.22 No.20
<P>We report on the signal monitoring characteristics in a reflective semiconductor optical amplifier (RSOA) transistor outline can with a monitor-photodiode, thermoelectric cooler, and thermistor. Because of spatial hole-burning in the RSOA cavity, a front-side signal-monitoring module exhibits wider windows and better linearity in monitor current to signal power ratio (MCSPR) than a rear-side signal-monitoring module for current variations. In C-band, the average of the MCSPR is about 0.150 A/W and the MCSPR variation on wavelength is about ±0.038 A/W.</P>
Characterization of Mouse Interferon-Induced Transmembrane Protein-1 Expression in Mouse Testi
Ran Lee,Hyun Jung Park,Won Young Lee,Ji Hyuk Kim,In Chul Kim,Dong Woon Kim,Sung Dae Lee,Hyun Jung Jung,Jong Moon Kim,Hyung Moon Yoon,Hyuk Jung Kwon,Hyuk Song 한국동물번식학회 2012 Reproductive & developmental biology Vol.36 No.3
Kalman Filter-based Wind Speed Estimation for Wind Turbine Control
Dong-Ran Song,Mi Dong,Jian Yang,주영훈 제어·로봇·시스템학회 2017 International Journal of Control, Automation, and Vol.15 No.3
To improve power production and reduce loads on turbine components, exact wind speed information isrequired in modern wind turbine controllers. However, the wind speed measured on the nacelle is imprecise becauseof its drawbacks of single point measurement and non-immunity to disturbances. To solve this problem, the EWS(Effective Wind Speed) estimator has been proposed as an alternative. According to the literatures, there are twokinds of EWS estimator, that is, the KF-based estimator and the EKF-based one. Where, the former is applied toestimate the aerodynamic torque, then the EWS is numerically calculated; and the latter directly estimate the EWS. Since the estimate EWS significantly affect the controller’s effectiveness, their performance needs to be clarified. To fully investigate the two estimators, there is a need to evaluate their performance on an even platform. In thispaper, we present comparative studies on these two methods. Their advantages and drawbacks are investigatedon the commercial turbine design software-bladed and compared through detailed simulation results. Finally, wedemonstrate some simulation results and differences between the KF-based estimator and the EKF-based one.
Test on the anchoring components of steel shear keys in precast shear walls
Shao-Dong Shen,Peng Pan,Wen-Feng Li,Qi-Song Miao,Run-Hua Gong 국제구조공학회 2019 Smart Structures and Systems, An International Jou Vol.24 No.6
Prefabricated reinforced-concrete shear walls are used extensively in building structures because they are convenient to construct and environmentally sustainable. To make large walls easier to transport, they are divided into smaller segments and then assembled at the construction site using a variety of connection methods. The present paper proposes a precast shear wall assembled using steel shear keys, wherein the shear keys are fixed on the embedded steel plates of adjacent wall segments by combined plug and fillet welding. The anchoring strength of shear keys is known to affect the mechanical properties of the wall segments. Loading tests were therefore performed to observe the behavior of precast shear wall specimens with different anchoring components for shear keys. The specimen with insufficient strength of anchoring components was found to have reduced stiffness and lateral resistance. Conversely, an extremely high anchoring strength led to a short-column effect at the base of the wall segments and low deformation ability. Finally, for practical engineering purposes, a design approach involving the safety coefficient of anchoring components for steel shear keys is suggested.
Zhong, Dong,Ran, Jian-Hua,Tang, Wen-Yuan,Zhang, Xiao-Dong,Tan, Yun,Chen, Gui-Jie,Li, Xiao-Song,Yan, Yi Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.6
Invasion is usually recognized as the main reason for the high recurrence and death rates of glioma and restricts the efficacy of surgery and other therapies. Therefore, we aimed to investigate the mechanism involved in promotion effects of mda-9/syntenin on human glioma cell migration. The wound healing method was used to test the migration ability of human glioma cells CHG-5 and CHG-hS, stably overexpressing mda-9/syntenin. Western blotting was performed to determine the expression and phosphorylation of focal adhesion kinase (FAK) and JNK in CHG-5 and CHG-hS cells. The migration ability of CHG-hS cells was significantly higher than that of CHG-5 cells in fibronectin (FN)-coated culture plates. Phosphorylation of FAK on tyrosine 397, 576, and 925 sites was increased with time elapsed in CHG-hS cells. However, phosphorylated FAK on the tyrosine 861 site was not changed. Phosphorylated Src, JNK and Akt levels in CHG-hS cells were also significantly upregulated. Phosphorylation of JNK and Akt were abolished by the specific inhibitors SP600125 and LY294002, respectively, and the migration ability of CHG-hS cells was decreased, indicating that the JNK and PI3K/Akt pathways play important roles in regulating mda-9/syntenin-induced human brain glioma migration. Our results indicate Mda-9/syntenin overexpression could activate FAK-JNK and FAK-Akt signaling and then enhance the migration capacity of human brain glioma cells.