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Kyu-shik Jeong,정원일,Jae-yong Chung,Mi-young An,Chae-yong Jung,Gyoung-jae Lee,Jong-soo Kang,Byeong-cheol Kang,Young-heun Jee,Bruce H Williams,Young-oh Kwon,Da-hee Jeong 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2
Cirrhosis Occurring in a Young Woodchuck (Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus (WHV)Da-hee Jeong, Won-il Jeong, Jae-yong Chung, Mi-young An, Chae-yong Jung, Gyoung-jae Lee1, Jong-soo Kang1, Byeong-cheol Kang2, Young-heun Jee3, Bruce H Williams4, Young-oh Kwon5 and Kyu-shik Jeong*College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Korea1Shinwon Scientific Co., LTD, Research Institute, Suwon, Korea2Clinical Research Institute, Seoul National University, Seoul 110-744, Korea3College of Veterinary Medicine, Jeju National University, Jeju 690-756, Korea
Oxalate와 Enrofloxacin투여한 랫트신장에 대한 병리조직학적관찰
오원석,이차수,오규실,정원일,정재용,정다히,정규식 한국임상수의학회 2003 한국임상수의학회지 Vol.20 No.4
To investigate the renal effects of enrofloxacin administration on rats induced with dehydration or hyperoxaluria, male rats were treated with enrofloxacin of 50 mg to 500 mg/kg b.w.. The microscopical observations of kidney and urine sediment were carried out in the experimental groups. The result obtained were as follows; The male rats deprived of water for 72 hours and administered with enrofloxacin. As enrofloxacin administration dose was increased, clinical signs such as loss of appetite, depression, weakness, and loss of urine output became more severe. In the histopathological findings, there were hyperemia and hemorrhage in renal cortex, vacuolation and necrosis of renal tubular epithelia, proteinous casts within renal tubules. The male rats were orally administered with sodium oxalate and injected with enrofloxacin for 7days. As enrofloxacin administration dose was increased, clinical signs such as the loss of appetite and water consumption, and weakness became more severe. In the histopathological findings, there are hemorrhage of glomeruli and cortical hyperemia, vacuolation and necrosis of tubular epithelia, proteinous casts in renal tubules. In the microscopical findings of urine sediment, there are calcium oxalate crystal (diamond-like type) and magnesium ammonium phosphate crystals (rhomboid). The male rats were intraperitoneally injected with sodium oxalate and administered with enrofloxacin for 7days. As enrofloxacin administration dose was increased, clinical signs such as the loss of appetite and water consumption, weakness were more severe. In the histopathological findings, there were hyperemia and hemorrhage in both glomeruli and renal cortex. Severe necrosis of renal tubular epithelia, bluish materials within renal tubules were also found. In the microscopical findings of urine sediment, there were many calcium oxalate crystals. The present results suggest that enrofloxacin has some injurious effects in rats having dehydration or hyperoxaluria, and clinically, we should consider these renal injury effects when we use enrofloxacin in patients accompanied renal disease, dehydration and hyperoxaluria conditions.
Influence of Nitrogen moieties on CO2 capture of Carbon Aerogel
Da-Hee Jeon,Byung-Gak Min,Jong Gab Oh,Changwoon Nah,Soo-Jin Park 한국탄소학회 2015 Carbon Letters Vol.16 No.1
Carbon aerogel is a porous carbon material possessing high porosity and high specific surface area. Nitrogen doping reduced the specific surface area and micropores, but it furnished basic sites to improve the CO2 selectivity. In this work, N-doped carbon aerogels were prepared with different ratios of resorcinol/melamine by using the sol-gel method. The morphological properties were characterized by scanning electron microscopy (SEM). Nitrogen content was studied by X-ray photoelectron spectroscopy (XPS) and the specific surface area and micropore volume were analyzed by N2 adsorption-desorption isotherms at 77 K. The CO2 adsorption capacity was investigated by CO2 adsorption-desorption isotherms at 298 K and 1 bar. Melamine containing N-doped CAs showed a high nitrogen content (5.54 wt.%). The prepared N-doped CAs exhibited a high CO2 capture capacity of 118.77 mg/g (at resorcinol/melamine = 1:0.3). Therefore, we confirmed that the CO2 adsorption capacity was strongly affected by the nitrogen moieties.
Poster Display : Occurrence of Fibrinous Bronchopneumonia in South American Sea Lion
( Da Hee Jeong ),( Won Il Jeong ),( Sun Hee Do ),( Dong Hwan Kim ),( Gi Ppeum Lee ),( Myung Hee Sohn ),( Hai Jie Yang ),( Dong Wei Yuan ),( Tae Hwan Kim ),( Young Ju Lee ),( Chang Woo Lee ),( Oh Deog 한국수의병리학회 2004 학술대회 Vol.2 No.-
A novel mutation in XLRS1 gene in X-linked juvenile retinoschisis
Da Hyun Kim,Sun Hee Heo,Go Hun Seo,Arum Oh,Taeho Kim,Gu-Hwan Kim,Young Hee Yoon,Han-Wook Yoo,Beom Hee Lee 대한의학유전학회 2018 대한의학유전학회지 Vol.15 No.1
X-linked juvenile retinoschisis (XLRS) is characterized by the progressive loss of visual acuity and vitreous hemorrhage. XLRS is caused by a mutation of retinoschisin 1 (RS1) gene at Xp22.13. In the current report, a 2-year-old Korean patient with XLRS was described. The germline deletion of exon 1 was identified in the RS1 gene. Considering X-linked inheritance pattern, validation of a carrier state of a patient’s mother is important for the genetic counseling of other family members and for the future reproductive plan. To confirm the carrier state of his mother, the multiplex ligation-dependent probe amplification analysis was done using peripheral leukocytes and found the heterozygous deletion of exon 1 in his mother
Poster Display : Occurrence of Fibrinous Bronchopneumonia in South American Sea Lion
( Da Hee Jeong ),( Won Il Jeong ),( Sun Hee Do ),( Dong Hwan Kim ),( Gi Ppeum Lee ),( Myung Hee Sohn ),( Hai Jie Yang ),( Dong Wei Yuan ),( Tae Hwan Kim ),( Young Ju Lee ),( Chang Woo Lee ),( Oh Deog 한국수의병리학회 2004 학술대회 Vol.8 No.-
Fibrinous Bronchopneumonia in South American Sea Lion
Da Hee Jeong,Won-Il Jeong,Sun-Hee Do,Hai-Jie Yang,Dong-Wei Yuan,Sang-Joon Park,Tae-Hwan Kim,Oh-Deog Kwon,Kil-Soo Kim,Keun-Woo Lee,Kyu-Shik Jeong 한국실험동물학회 2005 Laboratory Animal Research Vol.21 No.1
An 11-year-old male South American sea lion (Otaria Byronia) found dead in the near commercial aquarium. Animal had been shown chronic diarrhea, and had one-week history of anorexia. At necropsy, lung revealed severe hyperemia, hemorrhage diffusely and discolorization. Stomach and small intestine had hyperemia and mild hemorrhage grossly. Histopathological findings were significant hyperemia and fibrinous bronchopneumonia of lung, chronic catarrhal enteritis, and hyperplasia of lymphoid tissue. Morphological diagnosis was determinated as a fibrinous bronchopneumonia due to secondary infectious disease in asthenia state. Moreover, immune deficiency may be caused by chronic diarrhea, malnutrition, and environmental stress. In this study, necropsy case of sea lion was few occurred in our country. Therefore, our report may be useful for diagnosis clinically and interested veterinary practician.
말운동프로그램 향상을 위한 한국어 비단어 중재접근법의 확립 및 임상 적용
오다희(Da-Hee Oh),하지완(Ji-Wan Ha) 한국음성학회 2021 말소리와 음성과학 Vol.13 No.2
본 연구는 국외에서 개발된 비단어 중재접근법을 수정 및 보완하여 한국어 비단어 중재접근법을 확립하고, 아동기 말실행증 아동에게 직접 적용하여 그 효과를 확인하기 위해 실시되었다. 궁극적인 목적은 비단어를 이용한 중재가 아동기 말실행증의 말운동프로그래밍 능력을 개선시켜 비단어 산출 및 단어로의 일반화에 효과적인지 알아보기 위함에 있다. 중재는 아동기 말실행증의 진단 특성을 보이는 5세 6개월의 남아를 대상으로, ABA설계를 사용한 단일대상연구를 실시하였다. 중재에 사용된 비단어는 아동 맞춤형으로 제작하였으며, 한 회기당 60분씩 주 2회로, 총 12회기를 실시하였다. 그 결과 중재한 3음절 비단어의 모든 지표가 향상되었으며, 중재하지 않은 3음절, 4음절 비단어 및 단어로의 일반화를 확인하였다. 단, 단어로의 일반화 효과는 비단어로의 일반화 효과에 비해 미비하였다. 비단어 중재는 대상 아동의 말운동프로그래밍 능력을 개선시키는데 효과적이었다. 그 결과 운동프로그래밍 손상에 기인한 전환 오류가 크게 감소하였고, 중재하지 않은 비단어의 산출 능력이 큰 폭으로 증가하였다. 그러나 강력하게 습관화된 단어 오류를 완전히 개선시키는 데에는 한계가 있었으며, 이는 보다 집중적이고 반복적인 중재 일정을 제공했을 때 기대할 수 있는 결과일 것이다. This study is to develop a Korean version of nonword intervention by modifying and supplementing a Rapid syllable transition treatment (ReST) and to determine its effect by applying it to children with CAS. Ultimately, the purpose of this study is to investigate whether nonword interventions are effective for nonword production ability and generalization of real words. Single-subject research using the ABA design was performed for a child aged five years and six months with diagnostic features of CAS. The nonwords used in the interventions were made suitable for the individual child. The intervention was provided in one-hour sessions, twice a week for six weeks. In all cases, performance of the treated three-syllable nonwords improved, and untreated three-syllable words, four-syllable words, and nonwords showed a generalization effect. However, the generalization of treatment effects to words was smaller than for nonwords. The nonword intervention was effective in improving the subject"s speech motor programming skills. As a result, transition errors due to impaired speech motor programming were greatly reduced, and the ability to produce untreated nonwords was greatly increased. However, there was a limit to the full improvement of strongly habitable word errors, which would be expected if a more intensive and repetitive intervention schedule was provided.
Changes of Lipid Peroxide and Antioxidant Enzymes by UVB-Induced Oxidative Stress
Wook-Hee Choi,Ryoung-Me Ahn,Sun Hee Do,Da-Hee Jeong,Si-Yun Ryu,Dong-Mi Kwak,Oh-Deog Kwon,Kyu-Shik Jeong,Tae-Hwan Kim 한국실험동물학회 2006 Laboratory Animal Research Vol.22 No.3
Ultraviolet B (UVB) exposure is known to cause oxidative damage in the skin. In this study, we investigated the acute effects of UVB exposure on the skin and liver. Lipid peroxide levels, the mRNA level and activities of superoxide dismutase (SOD) and catalase (CAT) were examined in ICR mice which were exposed to a single dose of UVB (3 KJ/㎡). In the exposed skin, lipid peroxides increased at 3 h after the UVB exposure (p<.001) and then the amount gradually decreased in a time dependent manner. In the liver, lipid peroxides peaked at 24 h after the exposure and maintained at that level for up to 3 days (p<.001). The mRNA level and activity of SOD and CAT increased in the exposed skin, but there was no significant change reported in the liver. Our results exhibited that oxidative damage by the exposure of UVB has an effects not only on the exposed skin, but also on liver. The increase of the antioxidant enzymes in response to UVB, might induce the recovery of damaged lesions.