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Identifying Opinion Leader in the Internet Forum
Chao Wu,Chunlin Li,Wei Yan,Youlong Luo,Xijun Mao,Shumeng Du,Mingming Li 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.11
Opinion leader is an authority person who has great influence in BBS. Their linguistic behavior has a huge impact on net citizen’s behavior and thought. In this paper, we propose an algorithm called OLRA (Opinion Leader PageRank Algorithm) based on topic-field to identify opinion leaders in the Internet forum. In the algorithm the closeness degree factor and sentiment analyses are taken into consideration. Meanwhile, these two authority values are defined as the weight of links among users. The data is collected from a number of posts on Tianya forum which is a famous forum in China. In the experiment, the algorithm is compared with Interest-based PageRank algorithm, online time Algorithm, and Experience-based Algorithm, the result shows that the OLRA algorithm can identify opinion leaders than others in the Internet forum effectively.
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Qiu Mohan,Yu Chunlin,Zhu Shiliang,Liu Siyang,Peng Han,Xiong Xia,Chen Jialei,Jiang Xiaosong,Du Huarui,Li Qingyun,Zhang Zengrong,Yang Chaowu 한국유전학회 2022 Genes & Genomics Vol.44 No.11
Background: Long non-coding RNAs (lncRNAs) play an essential role in biological processes. However, the expression patterns of lncRNAs that regulate the non-Mendelian inheritance feather phenotypes remain unknown. Objective: This study aimed to compare the expression profiles of lncRNAs in the follicles of the late-feathering cocks (LC) and late-feathering hens (LH) that followed genetic rules and the early-feathering hen (EH) and early-feathering cock (EC) that did not conform to the genetic laws. Methods: We performed RNA sequencing and investigated the differentially expressed lncRNAs (DElncRNAs) between the early- and late-feathering chickens, which function by cis-acting or participate in the competing endogenous RNA (ceRNA) network. Results: A total of 53 upregulated and 43 downregulated lncRNAs were identified in EC vs. LC, and 58 upregulated and 109 downregulated lncRNAs were identified in EH vs. LH. The target mRNAs regulated by lncRNAs in cis were enriched in the pentose phosphate pathway, TGF-β signaling pathway and Jak-STAT signaling pathway in EC vs. LC and were associated with the TGF-β signaling pathway, Wnt signaling pathway, p53 signaling pathway and Jak-STAT signaling pathway in EH vs. LH. In addition, the lncRNA-mediated ceRNA regulatory pathways of hair follicle formation were mainly enriched in the TGF-β signaling pathway, Wnt signaling pathway, melanogenesis, and calcium signaling pathways. The levels of ENSGALG00000047626 were significantly higher in the late-feathering chickens than in the early-feathering chickens, which regulated the expression of SSTR2 by gga-miR-1649-5p. Conclusion: This study provides a novel molecular mechanism of lncRNA's response to the feather rate that does not conform to the genetic laws in chickens.
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A Case Study: Effects of Foot Reflexotherapy in an Infant with Sensorineural Hearing Loss
Yujun Lee,Qingchun Pan,Ying Du,Lantu Zhang,Chunlin Li,Minyong Hu,Mingxian Li,Bei Li 사단법인약침학회 2020 Journal of Acupuncture & Meridian Studies Vol.13 No.2
Sensoryneuronal hearing loss (SNHL) is one type of hearing impairment. The incidence of hearing loss (HL) is 1e3 per 1000 births. Complementary therapies may be effective in addressing the maladies of infants with HL. The aim of this study was to assess the efficacy of foot reflexotherapy in an infant with SNHL. The patient was a 3-month-old infant with SNHL. Pretest and post-test for HL were conducted using an audiologic method (auditory brainstem responses) combined with behavioral audiometry. The subject was treated with foot reflexotherapy for 30 min per session four times per week for a period of 24 weeks. Foot reflexotherapy was effective in auditory recuperation of an infant with SNHL. The results of this novel study suggest that foot reflexotherapy can be an effective complementary treatment for infants with SNHL, especially for those 3 to 9 months of age.
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Han Xiaohui,Ma Shifeng,Shi Zhewen,An Guoqing,Du Zhenbin,Zhao Chunlin 대한전기학회 2022 Journal of Electrical Engineering & Technology Vol.17 No.3
Dissolved gas analysis (DGA) method is widely used to detect the incipient fault of power transformers. This paper presents a novel DGA method for power transformer fault diagnosis based on Harris-Hawks-optimization (HHO) algorithm optimized kernel extreme learning machine (KELM). The non-code ratios of the gases are used as the characterizing vector for the KELM model, and the Harris-Hawks-optimization (HHO) algorithm is introduced to optimize the KELM parameters, which promotes the fault diagnostic performance of KELM. Based on dataset collected from IEC TC 10, the fault diagnosis capability of the proposed method is validated by different characterizing vectors and is compared with conventional KELM and other optimized KELM. Moreover, the generalization ability of the proposed method is confirmed by China DGA data. The results demonstrate that the proposed method is superior to other methods and is more effective and stable for power transformer fault diagnosis with high accuracy.
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Jing Zhang,Jing Wang,Xiong Zhang,Chunping Zhao,Sixuan Zhou,Chunlin Du,Ya Tan,Yu Zhang,Kaizhi Shi 대한수의학회 2022 Journal of Veterinary Science Vol.23 No.1
Background: Co-infections of the porcine reproductive and respiratory syndrome virus (PRRSV) and the Haemophilus parasuis (HPS) are severe in Chinese pigs, but the immune response genes against co-infected with 2 pathogens in the lungs have not been reported. Objectives: To understand the effect of PRRSV and/or HPS infection on the genes expression associated with lung immune function. Methods: The expression of the immune-related genes was analyzed using RNA-sequencing and bioinformatics. Differentially expressed genes (DEGs) were detected and identified by quantitative real-time polymerase chain reaction (qRT-PCR), immunohistochemistry (IHC) and western blotting assays. Results: All experimental pigs showed clinical symptoms and lung lesions. RNA-seq analysis showed that 922 DEGs in co-challenged pigs were more than in the HPS group (709 DEGs) and the PRRSV group (676 DEGs). Eleven DEGs validated by qRT-PCR were consistent with the RNA sequencing results. Eleven common Kyoto Encyclopedia of Genes and Genomes pathways related to infection and immune were found in single-infected and co-challenged pigs, including autophagy, cytokine-cytokine receptor interaction, and antigen processing and presentation, involving different DEGs. A model of immune response to infection with PRRSV and HPS was predicted among the DEGs in the co-challenged pigs. Dual oxidase 1 (DUOX1) and interleukin-21 (IL21) were detected by IHC and western blot and showed significant differences between the co-challenged pigs and the controls. Conclusions: These findings elucidated the transcriptome changes in the lungs after PRRSV and/or HPS infections, providing ideas for further study to inhibit ROS production and promote pulmonary fibrosis caused by co-challenging with PRRSV and HPS.
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