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重化學工業機械의 國産化方案에 關한 硏究 : 特히 窯業에 있어서의 燒成爐, 粉碎機, 排風機, 冷却機, 電氣集마器 自動枰量供給器 等의 製作을 目的으로
趙哲衡,朴碩喆,丁太權,宋鐵,桭達福,金基玉,朴煥奎,趙煥從,朴善鐘,金種一,李茂錫 朝鮮大學校 1977 綜合論文集 Vol.1977 No.-
This is to investigate the posibility of home manufacturing of heavy chemical industry machines, such as rotary kiln, crusher, blower, cooler, electrostatic precipitator and weighing feeder of cement plant. It is concluded that even though we can not make all of them (some of them are made now and some others are going to be made in the near future, some of them are made whole and some others are made partially), we can build or export the cement plant by importing the important machines which we can not make now and by substituting them with ours gradually.
간 세포암에서 VEGF, TGF-β1, b-FGF 발현의 의의
김성용,남충현,주종우,채만규,백무준,이문수,김형철,안현철,김홍수,김창진,김창호 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1
Purpose: Angiogenesis is important for the proliferation and the metastasis of solid tumors. The growth of a solid tumor is widely recognized to depend on the process of neovascularrozation. Without angiogenesis, tumors cease to grow beyond even a few milimeters in diameter. It has been shown that tumor vascular density is an independent prognostic marker in several types of human tumors and is known to correlate with poor prognosis. To date, many angiogenic factors have been identified, such as transforming growth factor-α(TGF-α), transforming growth factor-β(TGF-β), fibroblast growth factor family(FGF), vascular endothelial growth factor(VEGF), platelet derived endothelial cell growth factor(PD-ECGF), tumor necrosis factor-α(TNF-α), and angiogenin. Hepatocellular carcinoma(HCC) is the second most common tumor in Korean males and is known as a typical hypervascular tumor with frequent portal vein invastion. The authors identified the expreesion of VEGF, TGF-β1, and b-FGF in HCC specimens and evaluated the relationship between these growth factors and the clinicopathologic characteristics of HCC. Method: We reviewed the medical records of 30 patients who were diagnosed as hepatocellular carinoma treated with hepatic resection between January 1994 and December 1998 in Soonchunhyang University Chunan Hospital. The selection of the cases was decided according to the condition of paraffin block fixation. The prognostic factors such as age, sex, tumor size, concentration of serum α-fetoprotein, presence of liver cirrhosis, presence of tumor emboli in portal vein, TMN stage, amount of transfusion during the operation, hepatitis B virus(HBV) infection, and Edmonson-Steiner(E-S) grade were investigated. Relationship between the prognostic factors and the immunopathologic expression of the TGF-β1, b-FGF, and VEGF was examined. Result: Thirty patients (24 males, 6 females) were included in the current study. The patient's mean age was 50.6 years and the age ranged from 36 to 65 years. The mean size of the tumor was found to be 5.2cm. All the patients were follewed up for 7 to 63 months. Child's classification A patients were 23(76.7%)cases, B patients were 7(23.3%)cases, and C was none. Immunohistochemical staining of HCC tumor mass in VEGF expression patients were 17(56.7%), b-FGF expression patients were 10(33.3%), and TGF-β1 expression patients were 10(33.3%). VEGF expression or more than one positive expression among the three factors correlated with tumor size and the stage of HCC but did not correlated with other clinicopathological characteristics. TGF-β1 and b-FGF did not correlate with any clinicopathological characteristics. Conclusion: The results suggest that the expression of VEGF or more than one positive expression among the three factors in HCC cells may be a significant prognostic factor of HCC.
하상호과 및 人工地下水富化방식에 대한 考察 (Ⅰ) : 洛東江 下流部를 中心으로 On the lower course of Nak Dong River
吳英敏,金武植,李澄姸,鄭淳亨 동아대학교 환경문제연구소 1981 硏究報告 Vol.5 No.1
Some developing countries have utilized the River bed sand to purify water work resource having obtained much effect. But there are few study for the River bed filtration and the artifical ground water enrichment method in order to improve water quality in this country. This study is purposed to get some basic data for the actual condition and the anticipative filtering efficiency of the natural river bed sand of the lower Nak Dong River basin. Surfaced in this paper are the observations that 1. The filtering efficiency of COD, BOD, S.S and T.S. were not directly in creased with the filter depth over 150㎝ of its height. 2. The removal rate of COD, BOD, S.S and T.S. mark by turns 93%, 77%, 98% and 60%, respectively when the river bed sand of the lower course of the Nak Dong River is used as the filter media. 3. The more initial concentration of COD and BOD increase, the more filtering efficiency increases on the whole.
Chung, Yoon-Sok,Lim, Sung-Kil,Chung, Ho-Yeon,Lee, In-Kyu,Park, Il-Hyung,Kim, Ghi-Su,Min, Yong-Ki,Kang, Moo-Il,Chung, Dong-Jin,Kim, Yong-Ki,Choi, Woong Hwan,Shong, Min Ho,Park, Ji-Hyun,Byun, Dong-Won,Y Springer-Verlag 2009 Calcified tissue international Vol.85 No.5
<P>Patient preferences, convenience, and bone turnover markers were evaluated for the monthly ibandronate over the weekly risedronate regimen in Korean postmenopausal osteoporotic women. This was a 6-month, prospective, randomized, open-label, multicenter study with a two-period and two-sequence crossover treatment design. After a 30-day screening period, eligible participants with postmenopausal osteoporosis were randomized to receive either monthly oral ibandronate 150 mg for 3 months followed by weekly oral risedronate 35 mg for 12 weeks (sequence A) or the same regimen in reverse order (sequence B). Patient preference and convenience were evaluated by questionnaire. The changes in serum C-telopeptide after 3 months of treatment were analyzed. A total of 365 patients were enrolled in this study (sequence A 182, sequence B 183). Of patients expressing a preference (83.4%), 74.8% preferred the monthly ibandronate regimen over the weekly regimen (25.2%). More women stated that the monthly ibandronate regimen was more convenient (84.2%) than the weekly regimen (15.8%). There was no significant difference in the change in bone turnover marker between the two treatments. The two regimens were similarly tolerable. There were fewer adverse events in the monthly ibandronate group compared to the weekly risedronate group in terms of gastrointestinal side effects (nausea and abdominal distension). This study revealed a strong preference and convenience for monthly ibandronate over weekly risedronate in Korean postmenopausal osteoporotic women. There was no significant difference in change of bone turnover marker and safety profile between the two regimens.</P>
( Hyung Woo Kim ),( Joo Han Song ),( Kyung Soo Chung ),( Song Yee Kim ),( Eun Young Kim ),( Ji Ye Jung ),( Young Ae Kang ),( Young Sam Kim ),( Se Kyu Kim ),( Joon Chang ),( Moo Suk Park ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Azathioprine is widely used as an immunosuppressive drug in infiammatory bowel disease, many autoimmune disease and after organ transplantation to avoid rejection. Azathioprine has adverse reactions like hepatotoxicity. We report a case of azathioprine induced cholestatic hepatitis in patient with bronchiolitis obliterans organizing pneumonia(BOOP). A-37-year old woman was admitted because of pruritus and jaundice. She took transbronchial lung biopsy, bronchoalveolar lavage for cough, dyspnea and GGO patterns on chest computed tomography(CT) scan before she admitted. And it was revealed that she had BOOP. So she had been followed and treated for BOOP with prednisolone from 23th Nov 2012 and azathioprine from 8th Jan 2013. 42 days after taking Azathioprine, routine blood test was taken. Serum bilirubin, alkaline phosphatase(ALP), aspartate transaminase(AST), and alanine aminotransferase(ALT) was elevated(Bilirubin 4.4mg/dL, AST 75IU/L, ALT 104IU/L) and. Other laboratory test, including prothrombin time, serum albumin, and serum protein were within normal range. There was no history of alcohol abuse or herbal medication intake at this period. To exclude other reasons for hepatotoxicity, serological test was performed. The patient tested to negative for Hepatitis A, B, and C as well as for other markers of autoimmune hepatitis. CT scan showed hepatomegaly with lymph node enlargement and there was no evidence of bile duct obstruction. And TPMT(thiopurine methyltransferase) genotyping was done and revealed to be wild type. Azathioprine was stopped and she was monitored for laboratory changes. Because it was regarded as azathioprine induced cholestatic hepatitis and jaundice, we considered not to do liver biopsy. Day 55 after starting azathioprine therapy, total bilirubin reached peak (12.3mg/ dL). The patient was discharged on day 63 with cholestatic parameters of 115U/L(ALP), 36U/L(γ-GT), and 11.5mg/dL(total bilirubin). After 2 months, total bilirubin was decreased to normal(0.8mg/dL). Treatment of BOOP has been continued only with oral steroid.
소 白血病(Bovine Leukosis)에 관한 硏究 IV. 免疫擴散法과 補體結合反應法에 의한 抗體檢出 効果 比較
Moo Hyung Jun(全茂炯),Un Ik Chung(鄭雲翼),Bong Kyun Park(朴奉均),Soo Hwan An(安壽煥) 한국예방수의학회 1983 예방수의학회지 Vol.7 No.2
By using the bovine leukosis virus (BLV) antigens prepared from the culture fluid of BLV persistently infected fetal lamb kidney cells, a modification of complement fixation test was attempted to improve the specificity of the test for measurement of potency of BLV antigen, and efficiency of immunodiffusion test and the modified complement fixation test for detection of BLV antibodies in cattle sera was compared.
Long Length YBCO Coated Conductors Prepared by an MOD Process on Buffered Metallic Tapes
Chung, Kook-Chae,Yoo, Jai-Moo,Ko, Jae-Woong,Kim, Young-Kuk,Kim, Tae-Hyung,Ko, Rock-Kil The Korean Society of Superconductivity and Cryoge 2006 한국초전도저온공학회논문지 Vol.8 No.4
YBCO coated conductors have been fabricated by the reel-to-reel processing using TFA-MOD method. In this work, the fluorine-free Y & Cu precursor solution was synthesized to shorten the calcining time by reducing the evolution of HF gas, thus the meter-long YBCO precursor films can be made within few hours by the continuous slot-die coating & calcination step using the F-free Y & Cu precursor solution. The annealing step was followed to make the YBCO films by the reel-to-reel method with the vertical gas flow system onto the moving tape. To increase the growth rate of the YBCO films by enhancing the removal of HF gas, the low total pressure was adopted in the annealing processing. And the water partial pressure and the oxygen partial pressure were varied to optimize the growth conditions of the MOD-YBCO films on the buffered metal tape. FE-SEM and XRD were used to investigate the surface morphologies and the texture of the meter-long YBCO films. The end-to-end critical current $(I_c)$ of 63A/cm-width and the critical current density $(J_c)$of $0.9MA/cm^2$ with the thickness of $0.7{\mu}m$ were obtained in the 0.42m long coated conductor.
Chung, Hyung-Koo,Lee, Won-Kyu,Park, Hong-Gyu,Lee, Hak Moo,Jeong, Hae-Chang,Cho, Min-Cha,Seo, Dae-Shik Optical Society of America 2014 Optics express Vol.22 No.18
<P>Uniaxial alignment of liquid crystals (LCs) is prerequisite for a vast number of LC applications. To accomplish stable and uniform LC orientation, an alignment process to orient the LCs is required. Herein, we demonstrate a simple strategy for fabricating novel LC alignment layers that ensures well aligned LC, superior switching without any capacitance hysteresis, low transmittance loss, and high thermal stability with sufficient anchoring action. Thin films of reactive mesogens (RMs) were transferred onto conventional homeotropic polyimides from a UV-cured RM stamp via contact printing. LC displays using defect free RM/PI polymeric stacks exhibited superior electro-optic (EO) properties to those containing rubbed PI layers. This approach allows for the fabrication of various-mode LC displays such as twisted nematic (TN), in-plane switching (IPS), and optically compensated bend (OCB) mode LCDs by changing the combinations of RMs, base PIs and LCs.</P>