Current state of research about acupuncture for the treatment of COVID-19: A scoping review

Chen Chen,Jie Zhan,Hao Wen,Xiaojing Wei,Lu Ding,Chenyang Tao,Cui Li,Peiming Zhang,Yuyuan Tang,Jing-chun Zeng,Li-ming Lu 한국한의학연구원 2021 Integrative Medicine Research Vol.10 No.-

Background Since the outbreak of coronavirus disease (COVID-19), acupuncture has been widely used in the treatment of COVID-19. The research community has responded rapidly and has already published many research articles about this topic. Methods We searched PubMed, Embase, Cochrane Library as well as CNKI, Wanfang and VIP from January 1, 2020 to July 31, 2021. The dates of publication, language of publication, methodological characteristics and the key findings were analyzed separately. The data are presented as bar graphs, structured tables and figures. Results In this scoping review, 16 research articles were included: 7 case reports, 6 observational studies, 1 review, 1 RCT and 1 nonrandomized clinical trial. The majority of the articles (81.3%) were published by Chinese scholars, 12.5% articles were by scholars in the United States, and 6.3% articles were by scholars in Iran. The included studies reported that acupuncture could alleviate the symptoms of COVID-19 patients, shorten their hospitalization days, and is effective for the elderly. There were no side effects reported. The most frequent acupoints used were LI4, PC6, ST36 and KI3. They reported many obstacles in implementing acupuncture therapy for treating COVID-19 patients. Conclusion Acupuncture has a good effect for the treatment of COVID-19, but high-quality evidence support is still lacking. Coupled with the difficulties that acupuncturists experienced during the process of treatment, the promotion of acupuncture treatment for COVID-19 faces many obstacles. Background Since the outbreak of coronavirus disease (COVID-19), acupuncture has been widely used in the treatment of COVID-19. The research community has responded rapidly and has already published many research articles about this topic. Methods We searched PubMed, Embase, Cochrane Library as well as CNKI, Wanfang and VIP from January 1, 2020 to July 31, 2021. The dates of publication, language of publication, methodological characteristics and the key findings were analyzed separately. The data are presented as bar graphs, structured tables and figures. Results In this scoping review, 16 research articles were included: 7 case reports, 6 observational studies, 1 review, 1 RCT and 1 nonrandomized clinical trial. The majority of the articles (81.3%) were published by Chinese scholars, 12.5% articles were by scholars in the United States, and 6.3% articles were by scholars in Iran. The included studies reported that acupuncture could alleviate the symptoms of COVID-19 patients, shorten their hospitalization days, and is effective for the elderly. There were no side effects reported. The most frequent acupoints used were LI4, PC6, ST36 and KI3. They reported many obstacles in implementing acupuncture therapy for treating COVID-19 patients. Conclusion Acupuncture has a good effect for the treatment of COVID-19, but high-quality evidence support is still lacking. Coupled with the difficulties that acupuncturists experienced during the process of treatment, the promotion of acupuncture treatment for COVID-19 faces many obstacles.

Involvement of Cdc25c in Cell Cycle Alteration of a Radioresistant Lung Cancer Cell Line Established with Fractionated Ionizing Radiation

Li, Jie,Yang, Chun-Xu,Mei, Zi-Jie,Chen, Jing,Zhang, Shi-Min,Sun, Shao-Xing,Zhou, Fu-Xiang,Zhou, Yun-Feng,Xie, Cong-Hua Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10

Cancer patients often suffer from local tumor recurrence after radiation therapy. Cell cycling, an intricate sequence of events which guarantees high genomic fidelity, has been suggested to affect DNA damage responses and eventual radioresistant characteristics of cancer cells. Here, we established a radioresistant lung cancer cell line, A549R, by exposing the parental A549 cells to repeated ${\gamma}$-ray irradiation with a total dose of 60 Gy. The radiosensitivity of A549 and A549R was confirmed using colony formation assays. We then focused on examination of the cell cycle distribution between A549 and A549R and found that the proportion of cells in the radioresistant S phase increased, whereas that in the radiosensitive G1 phase decreased. When A549 and A549R cells were exposed to 4 Gy irradiation the total differences in cell cycle redistribution suggested that G2-M cell cycle arrest plays a predominant role in mediating radioresistance. In order to further explore the possible mechanisms behind the cell cycle related radioresistance, we examined the expression of Cdc25 proteins which orchestrate cell cycle transitions. The results showed that expression of Cdc25c increased accompanied by the decrease of Cdc25a and we proposed that the quantity of Cdc25c, rather than activated Cdc25c or Cdc25a, determines the radioresistance of cells.

A Comparative Study of Fishery Industry Competitiveness in China's Coastal Provinces

Li, Chun-Jie,Kim, Hyung-Ho,Yang, Jun-Won The Institute of Internet 2021 International journal of advanced smart convergenc Vol.10 No.2

Fishery industry is an important part of agricultural industry in coastal countries. The purpose of this study is to use the theory of industrial competitiveness for reference, use Analytic Hierarchy Process (AHP) and Delphi method to establish the evaluation index system, and analyze the fishery industry competitiveness of 11 coastal provinces in China. This study data came from China Fishery Statistical Yearbook 2020. The results show that Shandong Province is the most competitive province in fishery industry among the coastal provinces. The inter-provincial differences are great. Not only the resource endowment is the factor that affects the fishery industry competitiveness, but also the long-term profitability is too. The proportion of recreational fishery in the fishery economic output value has become one of the main indicators to measure the competitiveness of the fishery industry. The findings of this study suggest that all regions should adopt measures in accordance with local conditions, promote the integrated development of the fishery industry, enhance the added value of fishery products and enhance the competitiveness of fishery industry. The disadvantage of this study is that the fishery industry competitiveness of China's coastal provinces is only compared and analyzed. The future direction is to carry out a comparative study on the international competitiveness of fishery with other east Asian countries.

An Efficiency Analysis of Fishery Output in Coastal Areas of China

Chun-Jie Li,전준우,김형호 한국인터넷방송통신학회 2020 Journal of Advanced Smart Convergence Vol.9 No.3

The purpose of this study is to measure the productivity of fisheries in China's coastal areas (including inland and marine fisheries) and to analyze the factors influencing the development of fishery economy in each province by comparing regional differences. The input indicators used for efficiency analysis are fish farms, ships and staff numbers, and the output indicators are fish catch and net income. In this paper, we used six years of data from 2013-2018 and DEA-Malmquist index was used to analyze the efficiency of coastal fisheries production in 11 areas of China's coast. According to the analysis from 2013 to 2018, the fishery output efficiency in China's coastal areas has improved to some extent, but most provinces and regions are characterized by technological progress, and the technological efficiency still needs to be further improved. The conclusion can provide reference for the development planning and policy measures of regional fishery industry in China's coastal areas.

A Comparative Study of Fishery Industry Competitiveness in China's Coastal Provinces

Chun-Jie Li,Hyung-Ho Kim,Jun-Won Yang 한국인터넷방송통신학회 2021 Journal of Advanced Smart Convergence Vol.10 No.2

Fishery industry is an important part of agricultural industry in coastal countries. The purpose of this study is to use the theory of industrial competitiveness for reference, use Analytic Hierarchy Process (AHP) and Delphi method to establish the evaluation index system, and analyze the fishery industry competitiveness of 11 coastal provinces in China. This study data came from China Fishery Statistical Yearbook 2020. The results show that Shandong Province is the most competitive province in fishery industry among the coastal provinces. The inter-provincial differences are great. Not only the resource endowment is the factor that affects the fishery industry competitiveness, but also the long-term profitability is too. The proportion of recreational fishery in the fishery economic output value has become one of the main indicators to measure the competitiveness of the fishery industry. The findings of this study suggest that all regions should adopt measures in accordance with local conditions, promote the integrated development of the fishery industry, enhance the added value of fishery products and enhance the competitiveness of fishery industry. The disadvantage of this study is that the fishery industry competitiveness of China's coastal provinces is only compared and analyzed. The future direction is to carry out a comparative study on the international competitiveness of fishery with other east Asian countries.

Efficient photodegradation of volatile organic compounds by iron-based metal-organic frameworks with high adsorption capacity

Li, Ping,Kim, Sungsoon,Jin, Jie,Do, Hyung Chun,Park, Jong Hyeok Elsevier BV 2020 Applied Catalysis B Vol.263 No.-

<P><B>Abstract</B></P> <P>The efficient removal of volatile organic compounds (VOCs) is still challenging, and suitable strategies and auxiliary materials are lacking. Herein, we propose a highly efficient and stable iron-based metal-organic framework (Fe-MOF) in which the adsorption removal and photodegradation regeneration step alternate to realize repeatable and efficient removal of VOCs. A group of morphology-controlled Fe-MOFs serves as both the adsorbent and photocatalyst under ambient conditions to remove typical VOCs, <I>e.g</I>., toluene by relying on their high porosity and catalytic activity. The optimized Fe-MOF exhibits 100% adsorption removal efficiency for a toluene concentration of 460 ppm, and the Fe-MOF could be regenerated by converting the adsorbed toluene into harmless CO<SUB>2</SUB> under 1 SUN (100 mW/cm<SUP>2</SUP>) solar irradiation. More importantly, the Fe-MOF showed excellent durability during repeated adsorption and degradation processes for 100 cycles.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Adsorption and photodegradation integrate to remove VOCs. </LI> <LI> Fe-MOFs serve as both adsorbent and photocatalyst. </LI> <LI> Fe<SUP>2+</SUP> abundant surface promotes •OH formation. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

An Efficiency Analysis of Fishery Output in Coastal Areas of China

Li, Chun-Jie,Jeon, Jun-Woo,Kim, Hyung-Ho The Institute of Internet 2020 International journal of advanced smart convergenc Vol.9 No.3

The purpose of this study is to measure the productivity of fisheries in China's coastal areas (including inland and marine fisheries) and to analyze the factors influencing the development of fishery economy in each province by comparing regional differences. The input indicators used for efficiency analysis are fish farms, ships and staff numbers, and the output indicators are fish catch and net income. In this paper, we used six years of data from 2013-2018 and DEA-Malmquist index was used to analyze the efficiency of coastal fisheries production in 11 areas of China's coast. According to the analysis from 2013 to 2018, the fishery output efficiency in China's coastal areas has improved to some extent, but most provinces and regions are characterized by technological progress, and the technological efficiency still needs to be further improved. The conclusion can provide reference for the development planning and policy measures of regional fishery industry in China's coastal areas.

In Vivo Effects of Ginseng Saponins on Hair Follicle Development in C57BL/6 Mouse Model

Zheng Li,Li Juan Gu,Mi Ra Lee,Bai Shen Sun,Jing Jie Li,Dong Liang Zhang,Lei Liu,Chun Yan Wang,Zhen Wang,Beom Sik Yun,Chang Keun Sung 한국식품저장유통학회 ( 구 한국농산물저장유통학회 ) 2009 한국식품저장유통학회 학술대회 Vol.2009 No.-

Mini-Array of Multiple Tumor-associated Antigens (TAAs) in the Immunodiagnosis of Esophageal Cancer

Qin, Jie-Jie,Wang, Xiao-Rui,Wang, Peng,Ren, Peng-Fei,Shi, Jian-Xiang,Zhang, Hong-Fei,Xia, Jun-Fen,Wang, Kai-Juan,Song, Chun-Hua,Dai, Li-Ping,Zhang, Jian-Ying Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.6

Sera of cancer patients may contain antibodies that react with a unique group of autologous cellular antigens called tumor-associated antigens (TAAs). The present study aimed to determine whether a mini-array of multiple TAAs would enhance antibody detection and be a useful approach in esophageal cancer detection and diagnosis. Our mini-array of multiple TAAs consisted of eleven antigens, p53, pl6, Impl, CyclinB1, C-myc, RalA, p62, Survivin, Koc, CyclinD1 and CyclinE full-length recombinant proteins. Enzyme-linked immunosorbent assays (ELISA) were used to detect autoantibodies against eleven selected TAAs in 174 sera from patients with esophageal cancer, as well as 242 sera from normal individuals. In addition, positive results of ELISA were confirmed by Western blotting. In a parallel screening trial, with the successive addition of antigen to a final total of eleven TAAs, there was a stepwise increase in positive antibody reactions. The eleven TAAs were the best parallel combination, and the sensitivity and specificity in diagnosing esophageal cancer was 75.3% and 81.0%, respectively. The positive and negative predictive values were 74.0% and 82.0%, respectively, indicating that the parallel assay of eleven TAAs raised the diagnostic precision significantly. In addition, the levels of antibodies to seven antigens, comprising p53, Impl, C-myc, RalA, p62, Survivin, and CyclinD1, were significantly different in various stages of esophageal cancer, which showed that autoantibodies may be involved in the pathogenesis and progression of esophageal cancer. All in all, this study further supports our previous hypothesis that a combination of antibodies might acquire higher sensitivity for the diagnosis of certain types of cancer. A customized mini-array of multiple carefully-selected TAAs is able to enhance autoantibody detection in the immunodiagnosis of esophageal cancer and autoantibodies to TAAs might be reference indicators of clinical stage.

Complete Genome Sequence of Salmonella enterica Serovar Pullorum Multidrug Resistance Strain S06004 from China(s)

( Qiu Chun Li ),( Ya Chen Hu ),( Yin Fei Wu ),( Xiao Chun Wang ),( Xiao Lei Xie ),( Ming Xin Tao ),( Jun Lei Yin ),( Zhi Jie Lin ),( Yang Jiao ),( Li Juan Xu ),( Xinan Jiao ) 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.5

As Salmonella enterica serovar Pullorum remains a major economic problem for the poultry industries of countries with no efficient control measures, we presented a multidrug resistance strain S06004 (isolated from a clinically sick chicken in China in 2006) for genome sequencing. The genome comparison showed that the strain contained two prophages, the ST104 and prophage-4 (Fels2) of E. coli LF82, which were not detected in the only published genomes of S. Pullorum RKS5078 and CDC1983-67. In addition, the GyrA Ser83 point mutation, drugresistant genes, and many antibiotic pump systems that are present in S06004 may be contributing to the multidrug resistance of this strain.