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RISS 인기검색어
- 검색키워드
- 저자 : Chuanchuan Lin (검색결과 3 건)
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Bailong Tao,Chuanchuan Lin,Ai Guo,Yonglin Yu,Xian Qin,Kai Li,Hongchuan Tian,Weiwei Yi,Dengliang Lei,Lixue Chen 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.104 No.-
Infected wound healing remains a critical threat, which frequently delays the healing process and evenleads to severe life-threatening complications. Herein, we reported an effective anti-infection approach,which was based on copper ions-releasing hydroxyapatite/polydopamine (HA-Cu/PDA) nanocompositeswith photothermal effect. The HA-Cu/PDA nanocomposites was fabricated through a co-precipitationreaction between polydopamine (PDA)-coated hydroxyapatite nanoparticles (HA)-loaded Cu2+ (HA-Cu). Through a synergistic effect of released Cu2+ and photothermal efficiency of PDA coating, and the HACu/PDA nanocomposites exhibited extraordinary antibacterial capacities against Escherichia coli (E. coli)and Staphylococcus aureus (S. aureus). The nanocomposites presented good biocompatibility for mouseembryonic fibroblast (NIH-3T3) cells and promoted NIH3T3 cells to migrate toward wound sites. Additionally, this nanocomposite could stimulate the tissue remodeling-related gene expression toinduce the blood vessels formation, granulation tissues and collagen deposition, and eventually enhancewound healing. In vivo study further verified that HA-Cu/PDA nanocomposites with NIR irradiation couldsignificantly improve bacterial infected wound healing through the prominent antibacterial property,reduced inflammatory response, the formation of granulation tissue, collagen deposition, and angiogenesisability. Thus, this study develops a versatile strategy for a broad range of wound healing and skinreconstruction caused by bacterial infection.
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Qiu, Jialing,Lu, Xintao,Ma, Lianxiang,Hou, Chuanchuan,He, Junna,Liu, Bing,Yu, Dongyou,Lin, Gang,Xu, Jiming Asian Australasian Association of Animal Productio 2020 Animal Bioscience Vol.33 No.4
Objective: The objective of this study was to investigate the effects of low doses of organic trace minerals (iron, copper, manganese, and zinc) on productive performance, egg quality, yolk and tissue mineral retention, and fecal mineral excretion of laying hens during the late laying period. Methods: A total of 405 healthy hens (HY-Line White, 50-week-old) were randomly divided into 3 treatments, with 9 replicates per treatment and 15 birds per replicate. The dietary treatments included feeding a basal diet + inorganic trace minerals at commercial levels (CON), a basal diet + inorganic trace minerals at 1/3 commercial levels (ITM), and a basal diet + proteinated trace minerals at 1/3 commercial levels (TRT). The trial lasted for 56 days. Results: Compared to CON, ITM decreased (p<0.05) egg production, daily egg mass, albumen height, eggshell strength, yolk Fe concentration, serum alkaline phosphatase activity and total protein, and increased (p<0.05) egg loss and feed to egg ratio. Whereas with productive performance, egg quality, yolk mineral retention, and serum indices there were no differences (p>0.05) between CON and TRT. The concentrations of Fe and Mn in the tissue and tibia were changed notably in ITM relative to CON and TRT. Both ITM and TRT reduced (p<0.05) fecal mineral excretion compared to CON. Conclusion: These results indicate that dietary supplementation of low-dose organic trace minerals reduced fecal mineral excretion without negatively impacting hen performance and egg quality.
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Ma, Lianxiang,He, Junna,Lu, Xintao,Qiu, Jialing,Hou, Chuanchuan,Liu, Bing,Lin, Gang,Yu, Dongyou Asian Australasian Association of Animal Productio 2020 Animal Bioscience Vol.33 No.1
Objective: To investigate the effects of low-dose trace mineral proteinates on reproductive performance, mineral status, milk immunoglobulin contents and fecal mineral excretion of sows. Methods: Eighty crossbred sows (Landrace×Large White) were randomly allocated to two groups in a 135-day trail, from breeding through 21 d postpartum. The two treatments were inorganic trace minerals (ITM): a basal diet+inorganic iron (Fe), copper (Cu), manganese (Mn), and zinc (Zn) at 90, 15, 25 and 90 mg/kg, respectively and organic trace minerals (OTM): a basal diet+proteinates of Fe, Cu, Mn, and Zn at 72, 12, 20, and 72 mg/kg, respectively. Results: Compared with ITM, OTM significantly increased (p<0.05) the number of piglets with birthweight >1 kg, the litter weaning weight, and milk Fe, Cu contents. No significant differences (p>0.05) were observed on sow hair mineral contents or immunoglobulin M (IgM), IgG, and IgA contents in colostrum and milk. In comparsion to ITM, OTM decreased fecal Fe, Cu, Mn, and Zn contents of gestating sows (p<0.01) and Fe, Mn, and Zn in lactating sows (p<0.01). Conclusion: These results indicate that low-dose mineral proteinates can increase the number of piglets with birthweight >1 kg, the litter weaning weight and certain milk mineral concentrations while reducing fecal mineral excretion.
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