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Transanal rectopexy for external rectal prolapse
Chivate Shantikumar Dhondiram,Chougule Meghana Vinay,Chivate Rahul Shantikumar,Thakrar Palak Harshuk 대한대장항문학회 2022 Annals of Coloproctolgy Vol.38 No.6
Purpose: The surgical management of patients with full-thickness rectal prolapse (FTRP) continues to remain a challenge in the laparoscopic era. This study retrospectively assesses a cohort of patients undergoing a transanal suture sacro rectopexy supported by sclerosant injection into the presacral space under ultrasound guidance. Methods: Patients with FTRP underwent a sutured transrectal presacral fixation of 2/3 of the circumference of the rectum from the third sacral vertebra to the sacrococcygeal junction through a side-viewing operating proctoscope. The procedure was supplemented by ultrasound-guided injection into the retrorectal space of a 2 mL solution of sodium tetradecyl sulfate/polidocanol mixed with air. Patients were functionally assessed before and 6 months after surgery with the Agachan constipation score and the Pescatori incontinence score. Results: There were 36 adult patients (26 males; the range of age, 23–92 years). The mean operative time was 27 minutes (range, 23–50 minutes) with no recorded perioperative morbidity. The median follow-up was 66 months (range, 48–84 months) with 1 (2.8%) recurrence presenting 18 months after surgery. There were 19 patients (52.8%) who presented with incontinence before surgery with 17 out of 19 (89.5%) reporting improvement in their Pescatori score (P<0.001). No patient had worsening incontinence and there were no de novo incontinence cases. Constipation scores improved in 23 out of 36 patients (63.9%) with a mean score reduction difference of 7.91 (P=0.001). Conclusion: Transanal sutured sacral rectopexy with supplemental presacral sclerosant injection is safe and effective in the management of FTRP with sustained improvement in bowel function.
Athiyaman, Hemalatha,M, Athiyaman,Chougule, Arun,Kumar, HS Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.12
Background: Epidemiological studies have indicated an increasing incidence of radiation induced secondary cancer (SC) in breast cancer patients after radiotherapy (RT), most commonly in the contra-lateral breast (CLB). The present study was conducted to estimate the SC risk in the CLB following 3D conformal radiotherapy techniques (3DCRT) including wedge field and forward intensity modulated radiotherapy (fIMRT) based on the organ equivalent dose (OED). Material and Methods: RT plans treating the chest wall with conformal wedge field and fIMRT plans were created for 30 breast cancer patients. The risks of radiation induced cancer were estimated for the CLB using dose-response models: a linear model, a linear-plateau model and a bell-shaped model with full dose response accounting for fractionated RT on the basis of OED. Results: The plans were found to be ranked quite differently according to the choice of model; calculations based on a linear dose response model fIMRT predict statistically significant lower risk compared to the enhanced dynamic wedge (EDW) technique (p-0.0089) and a non-significant difference between fIMRT and physical wedge (PW) techniques (p-0.054). The widely used plateau dose response model based estimation showed significantly lower SC risk associated with fIMRT technique compared to both wedge field techniques (fIMRT vs EDW p-0.013, fIMRT vs PW p-0.04). The full dose response model showed a non-significant difference between all three techniques in the view of second CLB cancer. Finally the bell shaped model predicted interestingly that PW is associated with significantly higher risk compared to both fIMRT and EDW techniques (fIMRT vs PW p-0.0003, EDW vs PW p-0.0032). Conclusion: In conclusion, the SC risk estimations of the CLB revealed that there is a clear relation between risk associated with wedge field and fIMRT technique depending on the choice of model selected for risk comparison.
TiO2 based nanostructured memristor for RRAM and neuromorphic applications: a simulation approach
Dongale T. D.,Patil P. J.,Desai N. K.,Chougule P. P.,Kumbhar S. M.,Waifalkar P. P.,Patil P. B.,Vhatkar R. S.,Takale M. V.,Gaikwad P. K.,Kamat R. K. 나노기술연구협의회 2016 Nano Convergence Vol.3 No.16
We report simulation of nanostructured memristor device using piecewise linear and nonlinear window functions for RRAM and neuromorphic applications. The linear drift model of memristor has been exploited for the simulation purpose with the linear and non-linear window function as the mathematical and scripting basis. The results evidences that the piecewise linear window function can aptly simulate the memristor characteristics pertaining to RRAM application. However, the nonlinear window function could exhibit the nonlinear phenomenon in simulation only at the lower magnitude of control parameter. This has motivated us to propose a new nonlinear window function for emulating the simulation model of the memristor. Interestingly, the proposed window function is scalable up to f(x) = 1 and exhibits the nonlinear behavior at higher magnitude of control parameter. Moreover, the simulation results of proposed nonlinear window function are encouraging and reveals the smooth nonlinear change from LRS to HRS and vice versa and therefore useful for the neuromorphic applications.
G.D. Khuspe,S.T. Navale,D.K. Bandgar,R.D. Sakhare,M.A. Chougule,V.B. Patil 대한금속·재료학회 2014 ELECTRONIC MATERIALS LETTERS Vol.10 No.1
Nanocomposites of polyaniline (PANi) and tin oxide (SnO2) were prepared by adding SnO2 nanoparticles (NPs) in different weight ratios (0% -50%) into the PANi matrix. X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM) and transmission electron microscopy (TEM) were used to form the polyaniline-SnO2 nanocomposites (PANi-SnO2) - a polymer-composite. PANi films modified with SnO2NPs were prepared by the spin coating method. The gas sensing properties of PANi, SnO2 and PANi-SnO2 polymercomposite films were observed and it was found that: • The response of PANi film to 100 ppm NH3 at room temperature was 30% (stability 58%). • The response of SnO2 film to 100 ppm NO2 was 19% (stability 79%) at operating temperature 200°C, which is higher than the room temperature. However, SnO2 exhibited no response to NO2 and NH3 at room temperature. • The properties of the polymer-composite as a gas sensor were studied for various reducing (CH3OH, C2H5OH, NH3, H2S) as well as oxidising (NO2 and Cl2) gases. We demonstrated that the PANi-SnO2 (50%) polymer-composite film offers high stability and reproducibility and is a superior sensor to toxic gases operating at room temperature. (Results showed that they are highly selective to NH3 along with maximum response -72% to 100 ppm, fast-response time of 167 s and better stability - 86% at room temperature. The unique nanostructure of this polymer composite with its high surface area offers these advantages.