방사선 측정 및 해석 연구 : 원자로 냉각수중의 방사능해석에 의한 결함핵연료봉의 평가 Assessment of Defected Fuel by Analysis of Reactor Coolant Activities

양재춘,오희필,전재식,이호연,오헌진,정문규,박해용 충남대학교 기초과학연구소 1987 연구논문집 Vol.7 No.-

중성자와 우라늄의 핵반응에 의해 생성된 핵분열생성물의 물리적 특성을 이용하여 원자로 내의 핵연료 상태를 해석하는 모델을 개선하였다. 이 모델에서는 고체 핵연료 내에서 특정핵종의 핵분열생성물의 생성과 이것이 원자로 냉각재까지 방출되는 과정을 계산하고 추적하여 방사능농도와 결함 핵연료봉의 수를 관계짓는 방정식의 계수들을 결정한다. 핵분열생성물의 거동은 이탈(knock out)과 이동(migration) 두 부분으로 나누어 해석하였으며 트램프 우라늄의 영향을 분리할 수 있도록 하였다. 실측자료로는 가압 경수형 원자로인 고리 원자력발전소 1호기의 1차 냉각재를 분석해서 얻은 I-131과 I-133의 방사능 강도를 이용하였다. 이 실험자료와 위 방정식에서 구한 방사능 강도로부터 구한 결함 핵연료의 수는 제3주기에서 9.34±1.13개 제6주기에서 0.294±0.092개로 나타났다. An improved mothod of assessing fuel status by analyzsis of the fission product in the reactor coolant system is proposed. The release mechanism of specific fission products is established for determination of the coefficients in the equations which relate the radioactivities with the amount of detected fuel. Knock-out and migration models are employed in the formulation of the release mechanism. The influence of the tramp uranium is quantified. Sample calculations were made for KNU 1 reactor system using the I-131 and I-133 concentrations in the primary coolant. The estimated number of defected fuel pins in the third and sixth cycles appeared to be 9.34±1.13 and 0.294±0.092, respectively.

방사선 측정 및 해석 연구 : Assessment of Defected Feul by Analysis of Reactor Coolant Activities 원자로 냉각수중의 방사능해석에 의한 결합핵연료봉의 평가

이호연,오헌진,전재식,오희필,양재춘,정문규,박해용 대한방사선 방어학회 1986 방사선방어학회지 Vol.11 No.2

중성자와 우라늄의 핵반응에 의해 생성된 핵분열생성물의 물리적 특성을 이용하여 원자로 내의 핵연료 상태를 해석하는 모델을 개선하였다. 이 모델에서는 고체 핵연료 내에서 특정핵종의 핵분열 생성물의 생성과 이것이 원자로 냉각재까지 방출되는 과정을 계산하고 추적하며 방사능농도와 결합핵연료봉의 수를 관계짓는 방정식의 계수들을 결정한다. 핵분열생성물의 거동은 이탈(knock out)과 이동(migration) 두 부분으로 나누어 해석하였으며 트램프 우라늄의 영향을 분리할 수 있도록 하였다. 실측자료로는 가압 경수형 원자로인 고리 원자력발전소 1호기의 1차 냉각제를 분석해서 얻은 I-131과 I-133의 방사능 강도를 이용하였다. 이 실험자료와 위 방정식에서 구한 방사능 강도로부터 구한 결함 핵연료의 수는 제3주기에서 9.34±1.13개 제6주기에서 0.294±0.092개로 나타났다. An improved method of assessing fuel status by analysis of the fission product in the reactor coolant system is proposed. The release mechanism of specific fission products is established for determination of the coefficients in the equations which relate the radioactivities with the amount of defected fuel. Knock-out and migration models are employed in the formulation of the release mechanism. The influence of the tramp uranium is quantified. Sample calculations were made for KNU 1 reactor system using the I-131 and I-133 concentrations in the primary coolant. The estimated number of defected fuel pins in the third and sixth cycles appeared to be 9.34±1.13 and 0.294±0.092, respectively.

Root Yields and Saikosaponin Contents Depending on Planting Time and Cultivated Regions of Bupleurum falcatum L.

Choon-Shik Kim,Jae-Duck Seong,Chung-Heon Park,Chun-Gun Park,Yang-Hee Cho,Jun-Soo Kwak 한국약용작물학회 2005 한국약용작물학회지 Vol.13 No.5

In order to decide the optimum planting time for Bupleurum falcatum L. which is grown widely in Korea, some experiments were carried out in different regions such as mid-north area (Gangwon-do, Gyeonggi-do and Chungcheongnamdo), mid-south area (Jeollanam-do, Jeollabuk-do, Gyeongsangnam-do and Gyeongsangbuk-do). The mid-south area had the highest total saikosaponin contents of 1.001, which is the medicinal ingredients of Bupleurum falcatum L., in accordance with the different Bupleurum falcatum L. regions. Also this area has the highest extract contents of 24.3%. Average dry root yields in mid-north area (Gangwon-do) were 450~460 kg/ha at planting time of March 20th to March 30th, 500 kg/ha at the time of March 30th to April 10th, and 470~480 kg/ha at the time of March 10th to March 20th in Chungcheongnam-do. The optimum planting time in the mid-south area (Jeollabuk-do) was March 10th to March 30th with the average dry root yield of 490~550 kg/ha. Average dry root yield in Euiseong, Gyeongsangbuk-do area was 470 kg/ha, and the optimum planting time was April 10th, which suggested that the yield increased as the planting time was delayed. At Jeju-do, the volcanic soil of farsouthern area, average dry root yield was 510 kg/ha at the time of March 10th, but the yield from non-volcanic soil was lower than from volcanic soil, which had a dry root yield of 470 kg/ha.

Root Yields and Saikosaponin Contents Depending on Planting Time and Cultivated Regions of Bupleurum falcatum L.

Kim, Choon-Shik,Seong, Jae-Duck,Park, Chung-Heon,Park, Chun-Gun,Cho, Yang-Hee,Kwak, Jun-Soo The Korean Society of Medicinal Crop Science 2005 韓國藥用作物學會誌 Vol.13 No.5

In order to decide the optimum planting time for Bupleurum falcatum L. which is grown widely in Korea, some experiments were carried out in different regions such as mid-north area (Gangwon-do, Gyeonggi-do and Chungcheongnamdo), mid-south area (Jeollanam-do, Jeollabuk-do, Gyeongsangnam-do and Gyeongsangbuk-do). The mid-south area had the highest total saikosaponin contents of 1.001, which is the medicinal ingredients of Bupleurum falcatum L., in accordance with the different Bupleurum falcatum L. regions. Also this area has the highest extract contents of 24.3%. Average dry root yields in mid-north area (Gangwon-do) were $450{\sim}460$ kg/ha at planting time of March 20th to March 30th, 500 kg/ha at the time of March 30th to April 10th, and $470{\sim}480$ kg/ha at the time of March 10th to March 20th in Chungcheongnam-do. The optimum planting time in the mid-south area (Jeollabuk-do) was March 10th to March 30th with the average dry root yield of $490{\sim}550$ kg/ha. Average dry root yield in Euiseong, Gyeongsangbuk-do area was 470 kg/ha, and the optimum planting time was April 10th, which suggested that the yield increased as the planting time was delayed. At Jeju-do, the volcanic soil of farsouthern area, average dry root yield was 510 kg/ha at the time of March 10th, but the yield from non-volcanic soil was lower than from volcanic soil, which had a dry root yield of 470 kg/ha.

二面交配에 依한 고추果梗의 遺傳分析

曺洙憲,김낭춘 慶北大學校 새마을硏究所 1980 農村과 科學 Vol.3 No.-

고추 育種의 基礎資料를 얻고자 品種特性이 相異한 4個 品種을 二面交配하여 얻은 F_1 12組合과 新品種을 材料로하여 雜種强勢, 優性의 程度 및 方向, 遺傳力을 推定한바 그 結果를 要約하면 다음과 같다. 各形質에 있어서 F_1組合에 따라 正 또는 負의 heterosis와 heterobeltiosis를 나타내었고, 平均 heterosis는 果梗長, 果梗徑에서 正, 果梗重은 負, 平均 heterobeltiosis는 모두 負의 方向으로 雜種强勢를 보였다. 果梗長, 果梗徑, 果梗重 모두 部分優性을 나타내었다. 果梗長, 果梗徑은 正의 方向으로 優性을 나타 내었으나, 果梗重은 負의 方向으로 優性을 나타내었다. 遺傳力은 果梗長, 果梗徑, 果梗重등 모든 形質에서 相當히 높았다. This study was conducted to obtain basic information for the red pepper breeding. A complete dialle set(including the reciprocals) of four aprents were grown in a randomized block design with two replications. The percentage heterosis and heterobeltiosis, degree and drirection of dominace. and heritability were evaluated. Positive or negative heterosis and heterobeltiosis were observed in all the pedunce characters depending upon F_1 combinations. Average percentage of heterosis for peduncle length and width were shown in positive values, while peduncle weight was shown negative. Average percentage of heterobeltiosis in all characters of peduncle were shown in negative values. The length, width and weight of peduncle showed partial dominance. Direction of dominance were show positive in peduncle length and width, and negative in peduncle weight. Heritability values estimated in all characters were high in peduncle of red pepper.

임신중인 생쥐에 Bisphenol A 투여 후 태어난 차산자의 생식독성과 혈액성분에 관한 연구

박동헌(Dong-Heon Park),장현용(Hyun-Yong Jang),김정익(Choung-Ik Kim),정희태(Hee-Tae Cheong),박춘근(Choon-Keun Park),양부근(Boo-Keun Yang) 한국독성학회 2005 Toxicological Research Vol.21 No.2

Bisphenol A (BPA) is a monomer used in the manufacture of a multitude of chemical products, including epoxy resins and polycarbonate. The objective of this study was to evaluate the effects of BPA administration on reproductive characteristics and blood hematological and chemical values in offspring of pregnant dams treated with BPA. BPA was administrated to pregnant mice by intraperitoneally injection with 0, 0.05, 0.5 and 5.0 ㎎/㎏ B.W. for 5 times at 3 days interval on gestation days 1~16. There were no treatment-related effects of BPA on reproductive organ weight in male offsprings at 45 days-of-age, but body weight was the lowest in 5.0 ㎎ BPA group when compared to other groups (P<0.05). No differences in semen characteristics (sperm concentration, viability, motility and abnormality) were observed between the control and BPA treatment groups. The WBC, HB, HT, MCV, MCH, MCHC, albumin, BUN and total protein of blood hematological and chemical values in male offsprings were not difference for any treatment groups, but RBC value in BPA groups was significantly increased comparing to the control group (P<0.05). The PLT value was slightly higher in 5.0 ㎎ BPA groups than in any other group, but not significantly difference among the experimental groups. In female offsprings, the effects of BPA didn't affect to the body and ovary weight, but the uterus weight in 5.0 ㎎ BPA group was slightly heavier than that of control group (P>0.05). No statically significant difference in blood hematological values in female offsprings were observed between the control group and BPA groups, but the concentration of albumin and BUN were significantly higher in 0.5 ㎎ BPA group when compared to control and other BPA treatment groups (P<0.05). The histological evaluation of testis and ovary in growing offspring at 45 days-of-age was not difference between the control group and BPA groups, but endometriosis of the uterus in female offspring was dramatically increased in 0.5 and 5.0 ㎎ BPA groups. These founding suggest that low concentration of BPA might not have a important role on reproductive ability or blood metabolite in offspring of pregnant dams treated with BPA.

Analysis of Truck involved Accidents on Freeways

양충헌,손영태,Yang, Choon-Heon,Son, Young-Tae Korean Society of Road Engineers 2008 한국도로학회논문집 Vol.10 No.2

트럭은 상대적으로 낮은 운송비용과 그 운영의 탄력성 때문에 화물 운송에 가장 널리 이용되는 교통 수단이다. 그러나 전체 교통량에서 트럭교통이 차지하는 비율이 높은 곳에서는 심각한 안전 문제를 일으킬 수 있다. 트럭사고는 다른 차량간의 사고보다 더 심각한 부상이나 사상자를 야기 시킬 수 있다. 따라서, 트럭 교통과 관련된 안전 문제는 교통 시스템을 운영, 관리하는 공공부분과 이러한 시스템을 이용하는 일반 운전자에게 있어 중요한 문제이다. 본 연구에서는 트럭관련 사고 자료를 이용하여 교통 조건에 따른 사고 형태를 조사하고 통계기법을 사용하여 현장에서 조사된 사고 요인들 중 어떤 것이 가장 큰 트럭관련 사고 요인인지를 분석한다. 이 연구를 위한 자료는 TASAS의 database를 이용하였다. 중요 사고 요인이 분석이 되면, 효과적이고 효율적인 트럭 관리 전략에 대해 논의해 볼 수 있다. Trucking is the most frequently used mode for freight movement due to relatively lower shipping costs and its operational flexibility. However, truck traffic can contribute to serious safety problems where they occupy high percentage of the total traffic. Heavy truck crashes arc more likely to result in serious injuries and fatalities than are crashes involving light vehicles. Therefore, safety issues for truck traffic are very significant both for public agencies and for general travelers. The objective of our study is to find truck-involved accident patterns according to traffic conditions and main factors as well as to find the most critical factor through conventional statistical techniques. A vailable data were obtained from TASAS (Traffic Accident Surveillance and Analysis System). Once critical factors are identified, effective and efficient truck management strategies can be discussed.

임신중인 생쥐에 Bisphenol A 투여가 모체의 생식독성과 태아의 성비에 미치는 영향

박동헌(Dong-Heon Park),장현용(Hyun-Yong Jang),김정익(Choung-Ik Kim),정희태(Hee-Tae Cheong),박춘근(Choon-Keun Park),양부근(Boo-Keun Yang) 한국독성학회 2005 Toxicological Research Vol.21 No.2

Bisphenol A (BPA), a environmental endocrine disruptor, is considered to bind to estrogen receptors and to regulate the expressions of estrogen responsive genes. This study was to evaluate the effect of BPA administration on body weight, sex ratio and litter size on 18 days in prenatal periods, the effect of reproductive organ weight and blood hematological values on 24 days postpartum in pregnant mice. The female mice was administrated to low doses of BPA (0, 0.05, 0.5 and 5.0 ㎎/㎏ B.W.) by intraperitoneal injection in gestation days 0~15 with 5 times at 3 days interval. The maternal body weight, litter size and sex ratios were similar to in all experimental groups, but body weights of male and female offspring was significantly lower in 5.0 ㎎ BPA group when compared to any other groups (P<0.05). No treatment-related effects on body weight, ovary weight and blood hematological values were observed in dams on 24 days after delivery. The uterine weight in 5.0 ㎎ BPA group was slightly higher than those of any other groups, but not significantly difference. The histological evaluation of ovary in dam mice on 24 days after dilivery was not difference in all experimental groups, but the endometriosis of uterus in dam mice were significantly increased in 0.5 ㎎ BPA group when compared to control group. These results indicates that low concentration of BPA should not be considered as a selective reproductive toxicant.

식도암으로 오인된 원발성 식도 결핵 1 예

박수헌,김진일,양진모,김재광,선희식,박용범,방춘상,추교영,한준열 대한소화기내시경학회 2001 Clinical Endoscopy Vol.23 No.3

Tuberculous involvement of the esophagus is very rare even in the presence of extensive pulmonary tuberculosis or in the endemic area. This is resulted from local extension to the esophagus from contiguous tuberculosis organs or miliary spread. Such secondary involvement is more common than primary tuberculosis, in which there is no evidence of tuberculosis elsewhere. The diagnosis of esophageal tuberculosis may be difficult. So the radioogic, endoscopic, histologic findings and clinical feature including the response to chemotherapy may be needed to avoid misdiagnosis. Most cases can be treated sucdessfrlly with antituberculosis medication. A 67-year-old man was admitted to our hospital complaining of swallowing difficulty for 2 months. On the gastrofibroscopic examination, 22 ㎝ sized protruding mass with central deep ulceration was discovered at the mid-esophagus. The biopsy showed the ulcer with chronic granulomatous inflammation and multinucleated giant cells consistent with tuberculosis. After antituberculosis medication, the lesion of esophageal thberculosis was healed completely remaining minimal ulcer scar.

Oleifolioside A Mediates Caspase-Independent Human Cervical Carcinoma HeLa Cell Apoptosis Involving Nuclear Relocation of Mitochondrial Apoptogenic Factors AIF and EndoG

Yu, Hai Yang,Jin, Cheng-Yun,Kim, Kyoung-Sook,Lee, Young-Choon,Park, Shin-Hyung,Kim, Gi-Young,Kim, Wun-Jae,Moon, Hyung-In,Choi, Yung Hyun,Lee, Jai-Heon American Chemical Society 2012 Journal of agricultural and food chemistry Vol.60 No.21

<P>Apoptosis, the main type of programmed cell death, plays an essential role in a variety of biological events. Whereas “classical” apoptosis is dependent on caspase activation, caspase-independent death is increasingly recognized as an alternative pathway. To develop new anticancer agents, oleifolioside A was isolated from Dendropanax morbifera Leveille and the biochemical mechanisms of oleifolioside A-induced apoptosis in HeLa cells were investigated. Exposure to oleifolioside A resulted in caspase activation and typical features of apoptosis, although cell death was not prevented by caspase inhibition. Oleifolioside A treatment induced up-regulation of Bad, loss of mitochondrial membrane potential, nuclear relocation of mitochondrial factors, apoptosis-inducing factor (AIF), endonuclease G (EndoG), and apoptosis induction. This is the first report of anticancer activity of oleifolioside A, and nuclear translocation of AIF and EndoG in oleifolioside A-treated HeLa cells might represent an alternative death signaling pathway in the absence of caspase activity.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jafcau/2012/jafcau.2012.60.issue-21/jf3014475/production/images/medium/jf-2012-014475_0006.gif'></P>