흰쥐에서 가시오가피 발효물의 단회 및 반복투여 독성평가

조주현(Ju-Hyun Cho),박인재(In-Jae Park),백순옥(Soon-Ok Baik),최수영(Soo-Young Choi),최구희(Goo-Hee Choi) 한국식품과학회 2014 한국식품과학회지 Vol.46 No.2

본 연구에서는 사용된 가시오가피 영지버섯 발효물과 가시오가피 상황버섯 발효물에 대한 열수추출물을 최고 2 g/kg의 농도로 단회 투여한 SD-rats에 체중 변화, 임상증상 등에서 어떠한 독성도 관찰할 수 없었으며, 1 g/kg 이하의 농도로 4주간 반복 투여한 SD-rats에서도 체중변화, 임상증상, 장기 무게, 혈액학적 성상, 혈액생화학적 성상 등에서 어떠한 독성과 비정상적인 소견을 관찰할 수 없었다. 따라서, 본 연구의 결과로 볼 때 가시오가피 영지버섯 발효물 열수추출물(FM-5111)과 가시오가피 상황버섯 발효물 열수추출물(FM-5131)은 본 연구에서 사용한 농도 내에서의 안전성을 확인할 수 있었다. 황 함유 아미노산의 결핍은 여러 가지 간질환 등의 증상을 야기한다(27). 또한, Choi와 Ahn(28)은 오가피 부위별 50% (v/v) 메탄올 추출액의 전자공여능은 줄기 추출물에서 90.21%, 뿌리 추출물에서 85.71%로 높은 활성을 보고하여 오가피의 항산화능을 규명하였다. 따라서, 본 연구에 사용된 시료 또한 항산화능과 같은 기능성을 가질것으로 사료되며, 추가 연구로 아미노산 분석을 통해 황 함유 아미노산의 함량 변화를 분석하고 간 기능 개선 효능을 평가하여 안전성이 확보된 기능성 식품소재 개발 연구를 진행할 계획이다. In this study, the products of Acanthopanax senticosus fermentation were derived from the mycelia of 2 mushrooms, Ganoderma lucidum and Phellinus linteus, to determine their safety in Sprague-Dawley rats. Rats were orally administered the water extracts of A. senticosus fermentation products with G. lucidum (FM-5111) or P. linteus (FM-5131) at dose levels of 0.5, 1.0, or 2.0 g/kg for the single-dose toxicity test and 0.25, 0.5, or 1.0 g/kg for the repeated-dose toxicity test. There were no significant differences in body weight gain, feed intake, or water consumption between control and FM-5111- or FM-5131-treated rats. Hematological and blood biochemistry analysis revealed that none of the investigated parameters were affected by the A. senticosus fermentation products, and no remarkable lesions were observed upon histopathological analysis. We conclude that the A. senticosus fermentation products obtained from mushroom mycelia are safe for long-term administration and could be considered as multi-functional nutrients for the improvement of liver function and immunity.

대학급식의 미생물적 품질보증을 위한 HACCP의 적용 : 참치샐러드 Tuna Salad

김운주,최은희,최현미,배주희,채현숙 충북대학교 교육 ·생활연구소 생활과학연구센터 2002 생활과학연구논총 Vol.6 No.1

The purpose of this study was to evaluate the microbiological quality, and to assure the safety of the food production process in the university foodservice facilities in accordance with the Hazard Analysis Critical Control Point(HACCP) concepts. The kitchen layout and time-temperature relationship, miciobiological quality(total plate count, coliform) were assessed to identify the critical point during each of the production phases. The results were as follows: 1) The kitchen layout had to be improved because contamination area was not separated from non-contamination area, and work table was in contact with washing sink. 2) Some employee did not follow personal hygiene standards(hand washing), and did not wear proper working uniforms(hair restraints). 3) The production time of tuna salad was 120 min, and environment temperature was 20.1~26.0℃. Improper receiving temperature, inproper holding practices(without cover at room temperature) were observed. 4) In the purchasing phase of the raw materials, the microbiological quality of green pepper was not at acceptable level based on the TPC(2.3×10^6CFU/g)and coliform(>14,000 MPN/g). During washing phase TPC was decreased about 3 log cycle. After cutting and holding phase the level of TPC and coliform were increased rapidly. At serving phase the microbiological quality of tuna salad were not at acceptable level(TPC 3.3×10^6 CFU/g, coliform 11,000 MPN/g) according to the standard set(TPC <10^5 CFU/g, coliform <100 MPN/g) by Sorberg et al. 5) For tuna salad, critical control points were purchasing and receiving of fresh vegetables, washing, cutting, holding, mixing and serving phase.

Development of a Reduction Algorithm of GEO Satellite Optical Observation Data for Optical Wide Field Patrol (OWL)

Sun-youp Park,Jin Choi1,Jung Hyun Jo,Ju Young Son,Yung-Sik Park,Hong-Suh Yim,Hong-Suh Yim,Hong-Kyu Moon,Young-Ho Bae,Jang-Hyun Park 한국우주과학회 2015 Journal of Astronomy and Space Sciences Vol.32 No.3

An algorithm to automatically extract coordinate and time information from optical observation data of geostationary orbit satellites (GEO satellites) or geosynchronous orbit satellites (GOS satellites) is developed. The optical wide-field patrol system is capable of automatic observation using a pre-arranged schedule. Therefore, if this type of automatic analysis algorithm is available, daily unmanned monitoring of GEO satellites can be possible. For data acquisition for development, the COMS1 satellite was observed with 1-s exposure time and 1-m interval. The images were grouped and processed in terms of “action”, and each action was composed of six or nine successive images. First, a reference image with the best quality in one action was selected. Next, the rest of the images in the action were geometrically transformed to fit in the horizontal coordinate system (expressed in azimuthal angle and elevation) of the reference image. Then, these images were median-combined to retain only the possible non-moving GEO candidates. By reverting the coordinate transformation of the positions of these GEO satellite candidates, the final coordinates could be calculated.

<巫女圖>에 드러난 죽음의 문제

최현주 全南大學校 人文科學硏究所 1994 용봉인문논총 Vol.23 No.-

The purpose of this thesis is to analyze the meaning of death in Munyudo, which is important in Kim Dong-ri's literary works. Until now the death in Kim Dong-ri's novels has been considered as the recurrence of nihilism or fatal mysticism. But this thesis newly examines the meaning of death by drawing the idea of time from Munyudo. Munyudo consists of three stories. The stories are closely related and show the stream of time; the previous life, this world and the next. The plot of Munyudo correlates the story about Nang-yi's birth - the previous life, Mo-wha and Wook-yi's confrontation - this world and the picture of a shaman - the next life. The plot based on the circular idea of time, centering on father and daughter's arrival and departure, Wook-yi's appearance and disappearance (death), represents the conflicts of Mo-wha, Nang-yi and Wook-yi in the archetypal circular structure. It shows that the idea of time in Munyudo is universal and death of Mo-wha is not extinction in this world but rebirth in the new world. Thus Kim Dong-ri's idea of death is not based on the defeatism or nihilism but our people's mental inheritance believing everlasting circle of life.

대동맥-장골동맥 폐색증에 대한 경피경관 혈관성형술 및 스텐트삽입술의 누적개존율

최동현,이상목,고석환,홍성화,오수명,윤충,박호철,오주형 대한혈관외과학회 2004 Vascular Specialist International Vol.20 No.1

치아 순면 형태가 측색 기기를 이용한 치아 색상 측정 결과에 미치는 영향

최용진,박수정,조현구,황윤찬,오원만,박병주,황인남 대한치과보존학회 2007 Restorative Dentistry & Endodontics Vol.32 No.5

송아지고기 소시지와 시중에 판매되는 우육과 돈육 소시지 제품의 저장특성 비교

이주호, 최정석, 이현진, 정구용, 최양일 忠北大學校 農業科學硏究所 2013 農業科學硏究 Vol.29 No.1

This study was undertaken to compare the storage characteristics between veal sausage and commercial pork and beef sausages in Korean domestic market. We manufactured 3_types of sausages and purchased 2_types of sausages in the market: T1(B-company product), T2(O-company product) and we made T3(smoked veal sausage), T4(smoked veal sausage with pepper) and T5(cooked veal sausage) products. During 20 days of storage at 4oC, T5 showed significantly higher in TBA value and VBN value (p<0.05). But TBA and VBN values showed normal range in all products. T3, T4, and T5 showed higher total microbial count than T1 and T2 (p<0.05). According to the result, beef and pork sausages in the market showed different total microbial count and VBN values from those made in laboratory. This result could be come from the different additives used and manufacturing processes. However, all products can be stored up to 20 days in the cooler.

병리검사 처방오류 개선 시스템 구축

이현임,최영진,구숙희,양승주,김병로,김묘정,신일근,신미옥,서임선 한국의료QA학회 2006 한국의료질향상학회지 Vol.13 No.2

문제: 조직병리검사의 처방이 복잡하고 전문화됨에 따라 오류처방이 빈번하게 발생되고 이를 해결하기위한 프로세스가 복잡하여 부서간의 갈등과 업무의 가중, 또한 병원 수입 감소가 초래되었다. 목적: 발생된 오류처방의 유형과 발생율, 오류처방을 해결하기 위한 프로세스를 파악하여 이에 대한 문제점을 개선하여 업무의 효율성과 관련부서간의 부가업무 감소와 갈등해소, 더불어 병원수익을 향상시키는 것에 목표를 두고 활동하였다. 의료기관: 서울시에 소재한 종합병원 질 향상 활동: 조직병리검사 처방의 오류처방 발생 원인과 유형, 발생율을 조사하여 원인을 파악하고 개선을 위한 프로세스를 구축하여 질 향상을 도모하였다. 개선효과: 수술실에서 의뢰한 외과 입원환자의 일반조직병리검사 오류율은 개선 전 7.8%에서 개선 후 3.5%, 동결절편조직검사 오류율은 개선 전 28.6%에서 개선 후 0%로 이전보다 모두 개선되었다. 또한 수술실 간호사의 업무 만족도는 일반조직병리검사의 처방시 95%, 동결절편조직검사 처방시 90%로 높은 만족도를 보였다. 단 병리과의 경우 업무가 증가됨에 따라 초과근무시간이 증가하였다.

고등학교 과학 동아리 활동 경험이 학생들의 진로선택에 영향을 준 사례 연구

최원호,우규환,박현주 한국과학교육학회 2004 한국과학교육학회지 Vol.24 No.6

학교밖 과학교육과 과학 동아리 활동에 적극적으로 참여한 경험을 가지고 있는 이공계 전공 대학생과 과학동아리 지도교사를 대상으로 과학 동아리 활동과 활동에 대한 인식을 조사하였다. 과학에 흥미와 재능을 가지고 있는 학생들이 1)직업적 역할 모델로서의 열정 있는 교사의 지도를 받으며, 2)직접적 체험을 경험하며, 3)오랜 기간 동안 과학실험을 준비하여, 4)비슷한 재능과 흥미를 가진 또래의 과학 동아리들 앞에서 발표하는 경험은 학생들을 과학관련 진로로 격려하는 좋은 요인임을 알았다. 또한 연구 참여자들은 과학 동아리 활동이 인생의 진로를 선택해야하는 중요한 시기에 과학에 대한 긍정적인 태도 형성에 영향을 주었고, 자신들의 학문적 진로를 결정하는데 중요한 영향을 주었다고 믿었다. This study is the analysis of interview with science major student about the effect of science club experience on career decision. The special interview was planned and arranged to meet students as well as their teacher. Both of the student whose background had experience in the science club activity, field science education during their high school days are majoring in physics and biology. In Summary : 1) science teacher's guidance deeply impressed the student that they respect the teacher as a occupational role model. 2) they really enjoyed the hands-on activities joyful. 3) their experience lasted so long time to keep them to stay in science field. 4) they had an experience of speaking before peer science club students who had similar interest and talent. We found the above four factors were really influential to encourage the subject to major in science career.

주거지역에 따른 남·여 중학생의 체격 및 체력 발달추이

최현주,오수일 江原大學校附設體育科學硏究所 2004 江原大學校附設體育科學硏究所論文集 Vol.- No.27

The purpose of this study was to provide basic information to physical educators. at fields by investigating developmental change at physique and physical fitness of male/female middle school from 1st grade to 3rd grade students from 4 type of residential areas at Gangwondo (urban/rural/sea/mine area), and by confirming the reasons of change through analysis of BMI tendency. The subject was selected as appointing each 100 persons of male/female middle school 3rd students randomly from 4 areas, and performed analysis about the developmental difference according to subject's residential area and the increase ratio according to grades based on data from health record, then also examined BMI. Average/standard deviation of male/female physique & physiacal fitness was calculated respectively as well as in creased amount with collected data, and two-way ANOVA analysis was performed to compare physique and physical fitness. one-way ANOVA analysis was also performed to examine difference per residential area according to grades in case a correlation was observed between grades and residential area. The conclusions is as follows; 1. In the matter of male students, height , weight, chest, sitting height and fatness at urban area showed the highest value, and weight of rural area, height of sea area, chest of mine area showed lower value respectively. Amount of annual increase of height and weight was observed significantly from 1st grade to 2nd grade than from 2nd grade to 3rd grade, and male students of urban area showed highest value among overall school years. Chest of rural area showed the highest increase degree from 2nd grade to 3rd grade th from 1st grade to 2nd grade while no significance was onserved among school years at sitting height except slight decrease tendency as promotion to higher school year. Fatness in urban area showed the highest value for all school years with many cases of over-weight among 4 areas that indicates fatness is arising according to increase of weight and height. 2. In the matter of female students, no significance was observed at heigh, weight, chest according to their residential area, and amount of increase of weight and sitting height even decreased as promotion while mine area showed the highest degree of increase. No significant different was also found at fatness according to residential areas while 1st grad at sea are, 2nd grade at mine area and 3rd grade at urban/mine area showed higher frequency at over-weight case. 3. In the matter of male students, much higher record of 50m sprint was observed at rural/mine area, and the record of mine area increased most significantly as promotion. Overall tendency of increase was found as promotion at total area, and annual development decreased as being 2nd grade except urban area in which high improvement was observed. Similar feature was found at sit-up and urban area showed higher improvemendt of 2nd grade and 3rd grad. Mine area showed high record of standing long jump at 1st grade and 2ne grade while rural area shoued the highest impromement from 1st grade to 3rd grade. 1st grade of urban area, 2nd grade of rural area and 3rd grade of mine area showed high record at sit-stretching, and the highest improvement was observed at mine area from 1st grade to 3rd grad. Continuous improvement was found at running/walking long according promotion as 1st grade/3rd grade at sea area and senior at mine area showed the highest record respectively. 4. In the matter of female students, there was no significance at 50m sprint according to residential area as well as at degree of improvement by promotion. 1st grade of urban area, 2nd grade of sea area and 3rd grade of mine area showed the greatest record at 50m sprint. Hang-down record of rural area and sit-up record of urban area showed the highest one among whole school years respectively. The highest improvement degree from 1st grade to 3rd grade at standing long jump was found at ural/mine area. General improvement as promotion at sit-stretfhing was record at running /walking long while 3rd grade of rural area showed high one. It was observed that the record is decreasing according to promotion.