國民學校 敎師 自然 및 算數科 再敎育의 分析的 硏究 : Based on the Choong Buk Province

黃秉德,梁仁煥,崔炳文,趙璇衡,朴根生 淸州大學校 科學敎育硏究所 1977 淸州大學校 科學敎育硏究所 Vol.1 No.-

Our college has retrained many primary school teachers during 5 years is science, and during 4 years in case of mathematics. Many problems are found out in the process of retraining them in our school. This study is aimed to research the actual condition of the retraining and to find out the way to improvement from the problems. However, Our study will have some limitation as follows: (1) For our study, only 300 teachers are chosen from the total 1,869 attended at our college(Cheong Ju Teachers College) in 1976. (2) The administrational and financial affairs are analyzed only according to the Ministry of Education with UNICEF funds from 1972 to 1976, and (3) We didn't take any consideration of Ministry of Education Project in Suggesting the way of improvement. Following are some problems found in our study: 1) Throughout the nation, only 23% of primary school teachers were taught in science and mathematice reservice work during the 5 years, and it can be said that it takes about 20 years to retrained all the teachers without consideration of natural increase of teachers. 2) The proportion of selecting primary school teachers in all the country for this reservice training is extreme, for example, Jeju Province is 57.9%, Seoul 17.7%. 3) The proportion of woman teachers selected in Choong Buk primary school is only 3.5% of total woman teachers, who takes 32% of total Choong Buk primary teachers during 5 years. Therefore, it is said that the number is very little. 4) Some teachers have been reselected in the reservice training. In case of the Choong Buk Board of Education. the 6% of teachers selected once were reselected for 5 years. 5) When the test are enforced on attendants to get data before the reservice training. We could find that they didn't understand the basic concept of science except a grade under their charge. 6) In the process of inquiry study, they didn't know even the scientific terms of expectation and reasoning. 7) After 60 hours of reservice training course. We tested them about understanding of the contents of text, and their marks are from 10 to 100. the marks show large individual difference among them. 8) Some teachers may have neither teaching ability nor knowledge of the basic concept, that is 11.3% of total attendants are less than 30 marks in mathematics test. 9) It is too very large work to study reservice text during the 60 hours. 10) There are many difficult signs in the mathematics reservice text having no connection with the actual primary school mathematics text book. 11) In the reservice text of science, there are omitted the method of teaching materials production, the model of inquiry learning, and the evaluation method. 12) From the analysis of questionary response for finding the actual condition of administration of teaching materials, We could find out 15% of primary schools in Choong Buk Province do almost not prepare teaching materials, and 15% of its never put them to practical use. Therefore, We could say that total 30% of them have been teaching without teaching materials. 13) The 42% of attendants in mathematics class answer that they do not understand the new mathematical signs, and 42% of them answer the shortage of hours (60 hours) to understand their reservice text book. 14) The 25% of them answer that they teach children with cramming education, and almost of them want good teachers guide books. As mentioned above, there are found many problems to be solved for reservice training of science education in our country. Some of them will be solved in our study. So We find out its and We suggest the ways solving the problems as follows: A. On the administration of reservice training. 1) The reservice training work for primary school teachers is very significant and will have to be continued. 2) It will be done in not only summer vacation but also winter one for finishing immediatly all over the country. 3) The 60 hours of science reservice training course work are very short, and the classmember of attendants will be regulated. 4) The funds for reservice operation and travelling expenses for attendants will be realized. B. On selecting the attendants 1) When the attendants are selected, there will be consideration of age, rank, term of their service, sex and academic background. 2) as far as possible, it will be selected as homogeous groups, and it will be effective to teach them with division between class teacher and nonclass teacher. 3) When select attendants are it will be taken consideration of balance between city and province for the diffusion effect and parallel development in reservice training work. 4) It must give a chance to woman as same as to man teacher according to a rule of equal select chance. 5) The principal, instructor and school inspector will be reeducated for fixing of science curriculum. C. On reservice training text book 1) The text book must reedit moderatly for 60 hours, or the time of retraining for the text book finished will be extented. In our opinion, it is to be desired that the time have to be added. 2) The difficult signs must be omitted, taking into account for the mathematics knowledge and time of education period. 3) In the science reservice training text book, it must supplement the tack for framming of inquiry teaching plan, the method for making teaching materials, and the skill for replacing of teaching materials. D. For the curriculum management of science. 1) The Governmental Company must settle the shortage of science teaching materials in primary school. 2) For the charge of the old state of teaching method, the teachers must devote themselves to teach children without miscellaneous duties. 3) The authorities concerned (for example, Ministry of Education, Teachers College, etc.) must make guide books for science teachers, and supply them to primary school teachers. 4) It must be given the chance of long period reeducation to the incompetent primary school teachers, and problem will have to be studied under the situation of educational administration.

Rat의 복강내에 투여한 5-fluorouracil-polyglycolic acid 제형이 장기에 미치는 영향에 관한 연구

강대영,송규상,최정목,노승무,정경수,오정연,김진향,양준묵,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

For more effective intraperitoneal chemotherapy, the authers made 5-fluorouracil-polyglycolic acid composite disks(FU-PGA disks) with 5-fluorouracil and polyglycolic acid, a biodegradable polymer. We inserted the FU-PGA disk into the peritoneal cavites of Sprague-Dawley male rats, the control and three experimental groups; one FU-PGA disk insert group(300mg/kg), two FU-PGA disk insert group(600mg/kg), and three FU-PGA disk insert group(900mg/kg). The control group received a similar number of PGA disk inserts. A pharmacokinetic study was performed to measure the 5-fluorouracil concentration in the peritoneal fluid, blood, and tissues(liver, kidney and heart) at 24 hours, 72hours and 168 hours after insertion of the FU-PGA disk. Light and electron microscopic studies were done. The results were as follows: 1) The number of white blood cells and platelets decreased after FU-PGA insertion. The degree was proportional to the duration and amounts inserted. The change in the number of red blood cells varied slightly. 2) Light microscopically, slight changes were noted at 168 hours in the 3 disk insert group (900mg/kg). Mild fatty change and hepatocyte degeneration around the central veins of the liver were noted, with vacuolar degeneration in the proximal convoluted tubules of the kidney. 3) Electron microscopically,the liver showed focal increases of lipid droplets in the hepatocytes, and irregular nuclear membrane with focal nucleolar segregation of the fibrillar and granular elements. Also the double membranous structure of the hepatocytes and Kupffer cells was widened with bleb formation. The kidney showed wide separation of the nuclear double membrane in the proximal convoluted tubular cells and mesangial cells, with vacuolation and myelin figure formation in the mitochondria of the proximal convoluted tubular cells, at 72 hours and 168 hours in the 2 to 3 FU-PGA insert groups. The heart showed focal loss of cristae,vacuolation and myelin figure formation in the mitochondria of the 2 to 3 FU-PGA insert groups. In conclusion, despite the large amont of FU-PGA inserted, the histopathological changes in the liver, kidney and heart were slight, and consonant with the very low amount of 5-fluorouracil concentrations detected in the liver, kidney and heart. The above results suggest that the FU-PGA composite can serve as a new device for releasing drugs in a controlled manner and easily targeted to intraperitoneal organs. This device can improve the efficacy of intraperitoneal chemotherapy for gastric cancer.

Adult invasive pneumococcal disease in the Republic of Korea: Risk medical conditions and mortality stratified by age group

Kim, Jong Hun,Baik, Seung Hee,Chun, Byung Chul,Song, Joon Young,Bae, In-Gyu,Kim, Hyo Youl,Kim, Dong-Min,Choi, Young Hwa,Choi, Won Suk,Jo, Yu Mi,Kwon, Hyun Hee,Jeong, Hye Won,Kim, Yeon-Sook,Kim, Jeong Elsevier 2018 INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES Vol.74 No.-

<P><B>Abstract</B></P> <P><B>Objectives</B></P> <P>This study aimed to characterize the risk factors for mortality in adult patients with invasive pneumococcal disease (IPD) stratified by age groups, after implementation of the national immunization program of 23-valent polysaccharide vaccine (PPSV23) for those aged ≥65 years in the Republic of Korea (ROK).</P> <P><B>Methods</B></P> <P>Clinical data and pneumococcal isolates from adult patients with IPD (≥18 years of age) were collected prospectively from 20 hospitals through the nationwide surveillance program from March 2013 to October 2015.</P> <P><B>Results</B></P> <P>A total of 319 patients with IPD were enrolled. Median age was 69 years. Overall in-hospital mortality was 34.2%: 17.1% in those aged 18–49 years, 23.7% in those aged 50–64 years, 33.0% in those aged 65–74 years, and 51.0% in those aged ≥75 years (<I>p<</I> 0.001). In particular, early death within 7days of hospitalization accounted for 60.6% (66/109). While old age (≥65 years), higher Pitt bacteremia score (≥4), and bacteremic pneumonia were independently associated with IPD mortality in all age groups, an additional mortality risk factor of immunocompromised status was identified for patients aged 50–64 years. PPSV23 serotypes accounted for 64.4% (122/189) of the pneumococcal isolates serotyped.</P> <P><B>Conclusions</B></P> <P>This study suggests that vaccine-type IPD continues to place a substantial burden on older adults in the ROK, necessitating an effective vaccination strategy for those at higher risk.</P> <P><B>Highlights</B></P> <P> <UL> <LI> National immunization of the elderly with the 23-valent polysaccharide vaccine (PPSV23) was implemented in Korea in 2013. </LI> <LI> Overall in-hospital mortality was 34.2% for adult invasive pneumococcal disease (IPD) and 51.0% for patients ≥75 years of age. </LI> <LI> Mortality risks were older age, higher bacteremia score, and immunocompromised status. </LI> <LI> An effective vaccination strategy for those at higher risk of IPD is needed. </LI> </UL> </P>

급성 중독 환자에 대한 역학적 고찰 : 서울과 지방의 비교

김성중,김인병,최성욱,김경수,이영수,Choi, Jong Moo 대한응급의학회 1995 대한응급의학회지 Vol.6 No.2

Study objective: To compare patients with acute poisoning between urban and rural areas Design: Retrospective chart review of 217 patients with acute poisoning Setting: Two University Hospital EDs Methods: patients were divided into two groups according to hospital. The group A was 109 patients who came to ED of Asan Medical Center and the group B was patients who came to ED of Ajou University Hospital from June 1994 to February 1995. We analysed the age and sex distributions, poisoning substances. causes of poisoning and the past history of psychiatric problems in patients of the two groups. Results: Total number of patients with acute poisoning were 109 in the group A and 108 in the group B. Female was more prevalent than male in the group A and male was more than female in the group B. There was a significant difference in sex distribution between two groups. The mean age of the group A was 27.7 years which was significantly different from the mean age of the group B, 33.7 years. The age incidences in both group were highest in 2nd decade. The accidental poisoning cases were 37% in the group A and 31% in the group B. The rates of committed suicide were 7% in the group A and 22% in the group B. The most common agent of poisoning was therapeutic drug in the group A and agricultural or industrial chemical in the group B. The overall mortality was 5% in the group A and 15% in the group B. Conclusion: There were significant differences in age and sex distributions. poisoning substances, causes of poisoning and the past history of psychiatric problems between two groups.

이산화질소 및 아황산 가스에 노출된 흰쥐에 대한 連翹敗毒散과 수종 한약물에 대한 실험적 연구

崔仁和,蔡炳允 慶熙大學校 1997 論文集 Vol.26 No.-

Sulfur dioxide and nitrogen dioxide are two major air pollutants. As it has been well known, the former plays indispensible role in London type smog incident and the latter is one of major components of photochemical oxidants. In the of industrial toxicology these two noxious gases are classified as irritant gas physiologically. And many reports on the acute and chronic intoxication by these two gases have been filed. Especially,a strong irritating nitrogen dioxide effect on the epithelium of air way tract are the formation or methemoglobin has been known as the main toxic action. Clinically pulmonary edema and congestion are beli-eved to main causes of death. Yongyopaedoksan(연요패독산) has been used in the oriental medical treatment of acute and chrom respiratory diseases, including laryngeal disorders and ocular irritant symptoms such as congestion burning, itching and scratch and so on. In order to investigate the clinical effect of Yongyopaedoksan(연요패독산), Maekmundong(麥門冬) Saengjihwang(生地黃) and Ilhwangyon(日黃連) on the rats exposured to 50ppm SO_2 & NO_2 for 5 hours an experimental study was done on hematologic changes, organ water contents and histopathologic pictures. The experimental groupe are the normal group, control group, S-1 group(oral medication Yongyopaedoksan), S-2 group(oral medication of Maekmundong), S-3 group(oral medication of Saengjihwang) and S-4 group(oral medication of Ilhwangyon). The results were summarized as follows; 1. On the hematologic change in the rats exposured to SO_2 in the Yongyopaedoksan group compared to the control, the increase in the value of hemoglobin & leucocytes was significant. In Maekmundong group, the number of leucocytes & eosinophil ratio were different significantly. In Saengjihwang group, the hematocrit values were increased significantly. 2. On the hematologic change in the rats exposured to NO_2 in the Yongyopaedoksan group compared to the control the hemoglobin hematocrit values and eosinophil ratio were decreased significantly. However the number of leucocytes was increased significantly. In the Maekmundong group, the reduction of hemoglobin & hematocrit values was significant. In the Saengjihwang group, the value of hemoglobin was reduced significantly. In the Ilhwangyon group, the decrease of the eosinophil ratio was significant. 3. On the change of water contents of left lung in the SO_2 exposure group, the Yongyopaedoksan Maekmundong & Saengjihwang group as compared to the control. the reduction was significant. 4. In the laryngeal histopathologic changes of SO_2 exposure group, all the sample groups were admitted of significant difference at congestion & inflammatory infiltrates as compared to the control. The edema of trachea in Saengjihwang & Ilhwangyon group as compared to the control were improved significantly. The congestion & inflammatory infiltrates of trachea ti four sample groups as compared to the control were improved significantly. 5. In the case of NO_2 exposure group, the edema and inflammatory infiltrates of larynx in Ilhwangyon on group as compared to the control were improved significantly. The edema of trachea in Saengjihwang & Ilhwangyon group as compared to the control was improved significantly. And the congestion & inflammatory infiltrates of trachea in all the sample groups as compared to the control were improved significantly.

1~2기 본태성 고혈압 환자들에서 Imidapril 대 Enalapril의 항고혈압 효과를 평가하기 위한 무작위, 이중맹검 임상시험

최영진,손대원,김용진,이홍자,채인호,김효수,김철호,오병희,이명묵,박영배,채윤식,이영우 대한순환기학회 1999 Korean Circulation Journal Vol.29 No.11

적외선열화상장치를 이용한 Buchanan plugger 표면의 온도상승 분석

최성아,김선호,황윤찬,윤창,오병주,최보영,정우남,정선와,황인남,오원만 大韓齒科保存學會 2002 Restorative Dentistry & Endodontics Vol.27 No.4

This study was performed to evaluate the temperature rise on various position of the Buchanan plugger, the peak temperature of plugger's type and the temperature change by its touching time of heat control spring. The heat carrier system 'System B' (Model 1005. Analytic Technologies, USA) and the Buchanan's pluggers of F, FM, M and ML sizes are used for this study. The temperature was set to 200℃ which Dr. Buchanan's "continuous wave of condensation" technique recommended on digital display and the power level on it was set to 10. In order to apply heat on the Buchanan's pluggers, the heat control spring was touched for 1, 2, 3, 4 and 5 seconds respectively. The temperature rise on the surface of the pluggers were measured at 0.5 mm intervals from tip to 20 mm length of shank using the infraed thermography (Radiation Thermometer-IR temper, NEC San-ei Instruments, Ltd, Japan) and TH31-702 Data capture software program (NEC San-ei Instruments, Ltd, Japan). Data were analyzed using a one way ANOVA followed by Duncan's multiple range test and linear regression test. The results as follows. 1. The position at which temperature peaked was approximately at 0.5 mm to 1.5 mm far from the tip of Buchanan's pluggers (p<0.001). The temperature was constantly decreased toward the shank from the tip of it(p<0.001). 2. When the pluggers were heated over 5 seconds, the peak temperature by time of measurement revealed from 253.3±10.5℃ to 192.1±3.3℃ in a touch for 1 sec, from 218.6±5.0℃ to 179.5±4.2℃ in a touch for 2 sec, from 197.5±3.0℃ to 167.6±3.7℃ in a touch for 3 sec, from 183.7±2.5℃ to 159.8±3.6℃ in a touch for 4 sec and from 164.9±2.0℃ to 158.4±1.8℃ in a touch for 5 sec. A touch for 1 sec showed the highest peak temperature, followed by, in descending order, 2 sec, 3 sec, 4 sec. A touch for 5 sec showed the lowest peak temperature (p<0.001). 3. A each type of pluggers showed different peak temperatures. The peak temperature was the highest in F type and followed by, in descending order, M type, ML type. FM type revealed the lowest peak temerature (p<0.001). The results of this study indicated that pluggers are designed to concentrate heat at around its tip, its actual temperature dose not correlate well with the temperature which Buchanan's "continuous wave of condensation" technique recommended, and finally a quick touch of heat control spring for 1 sec reveals the highest temperature rise.

췌담관 합류이상이 있는 환자에서 담도계 손상 기전에 대한 연구

정인호,정용식,김지훈,최수윤,김정운,김욱환,홍정,왕희정,유병무,김진홍,한재호,김영배,김재근,김명욱 한국간담췌외과학회 2003 한국간담췌외과학회지 Vol.7 No.2

소아 척수종양 24예의 임상분석(1973~1986) : Clinical Analysis of 24 Cases(1973~1986)

조병규,박인성,왕규창,최길수 대한신경외과학회 1988 Journal of Korean neurosurgical society Vol.17 No.6

The authors analyzed 24 cases of intraspinal tumors in children who had been operated upon at the Seoul National University Hospital from 1973 to 1986. The ratio of male to female was 2 : 1. The pathologic diagnosis revealed neurogenic tumor in 8 cases(33%), metastasis in 3 cases(13%), glioma in 3 cases(13%), lymphoma in 3 cases(33%), metastasis in 3 cases(13%), sarcoma in 3 cases(13%), and tumor of dysembryogenesis in 2 cases(8%). The tumors were located most frequently in the thoracolumbar area(7 cases, 29%) and in the epidural space(12 cases, 50%). Two thirds of the epidural tumors were malignant. The most common initial presentation was motor weakness(9 cases, 38%). Three cases(13%) presented with mass and one case(4%) with flexion deformity. On admission 9 cases(38%) were in the paraparetic stage, 6 cases(25%) in the radiculopathic stage, and 6 cases in the Brown-Sequard syndrome stage. The mean value of the CSF protein was 1, 108 mg%. Plain spine X-rays were abnormal in 17 cases(74%) and the increased interpedicular distance(11 cases, 48%) was the most common radiological abnormality. Myelographic studies were performed in 21 cases and all of them revealed abnormal findings. Total and gross total removal was possible in 13 cases(54%). Radiation therapy was done in 8 cases(33%) and chemotherapy in 5 cases(21%). The surgical result on discharge or at the postoperative one month was recovery in 7 cases(29%), improvement in 10 cases(42%), stationary state in 4 cases(17%), and progression in 3 cases(13%). After 20.8 months of mean follow-up duration in 20 cases(84%), the result was recovery in 13 cases(65%), improvement in 2 cases(10%), stationary state in one case(5%), and progression in cases(20%). As a major complication, there was a spinal deformity in 6 cases(29%) among 21 cases who did not have spinal deformity preoperatively. Three cases(13%) were followed up to their deaths. And the authors discussed the clinical features of the pediatric intraspinal tumors reported in the literature and the results of the present study.

한국인에서 혈소판 당단백 Ⅲa 유전자 다형성과 급성 관동맥 증후군의 관계

김광일,채인호,김효수,손대원,오병희,이명묵,박영배,최윤식,이영우 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.5