Retiform Hemangioendothelioma of the Neck

Chin-Lung Kuo,Pen-Yuan Chu,Paul Chih-Hsueh Chen,Wing-Yin Li 대한병리학회 2015 Journal of Pathology and Translational Medicine Vol.49 No.2

주제 : 인간성 회복을 위한 체육의 역할 ; 인간석 회복을 위한 체육교육

(Chin Lung Fang) 한국체육교육학회 1997 인간성 회복을 위한 체육의 역할 Vol.- No.-

Community Intervention on the Physical Fitness and Attitudes of Worksite Employees in Taiwan

Fang, Frank Chin Lung 한국운동과학회 1999 운동과학 Vol.8 No.1

대만직장인의 체격과 운동참가 태도에 대한 Community Intervention의 역할. 운동과학 제8권 제1호, 1-8, 1999. Community Intervention은 직업종사자들의 체력과 운동활동참가를 촉진시키기 위한 실용적이고 효과적인 전략이다. 이 연구의 목적은 체력에 관한 intervention 전략의 효과와 직업 종사자들의 운동에 대한 태도를 조사하기 위한 것이다. Department of Health of the Executive Yuan, R.O.C.의 빌딩에서 근무하는 126명의 종사자들은 이 연구에 참가하였고 체력검사와 일련의 운동에 참가하였다. 3개월 동안 지속되었던 일련의 전략은 체력에 관한 강의, 운동기술시범, 재료운반, 체력에 관한 벽보, 행정적 지원, 가장 열심히 참가한 사람에 대한 시상들은 포함하였다. 더구나, 업무시간동안 엘리베이터를 이용하는 대신에 계단을 이용하는 프로그램이 제안되었고 기록표에 기록을 기입하도록 하였다. BMI, WHR(waist and ratio), 1분간의 팔굽혀 펴기(근지구력), 앉은체전굴(유연성, 3분간의 스텝 테스트(심혈관능력)를 포함한 건강과 관련된 체력검사가 Community Intervention Program 실시전과 실시 3달 후 실시되었다. 자료분석을 위해서 반복적 T-test방법이 사용되었고 결과는 다음과 같다. 1. WHR, 근지구력과 심혈관능력은 intervention program 실시후 유의하게 증가하였다(P<0.05). 2. 실험참가자 자신이 기입하는 설문지에서 97% 이상이 체력검사를 보다 쉽게 수행할 수 있다거나 변화가 없었다고 지적하였고, 97.5%는 intervention 이후 전체적인 체력이 증가되었거나 변화가 없었다고 지적하였다. 3. community intervention program은 거의 모두 실험 참가자들에 의해 지지되었고 81%는 이 프로그램이 상당히 의미있다고 생각하였고 19%는 응답을 하지 않았다. 운동참가에 대한 태도에서 78%는 긍정적으로 좋아졌다고 대답하였고, 22%는 변화가 없다고 하였다. 약 70%는 intervention 전략은 규칙적인 운동에 참가하는 습관을 증가시켰다고 응답하였다. 이렇게 디자인된 community intervention program은 체력을 증가시킬 뿐만 아니라 대만의 직업종사자들의 운동참가에 대한 태도를 긍정적으로 바꾸었다. 따라서 체력향상을 위한 intervention 전략은 관련된 회사, 공장과 연구소 등에서 추천할만한 것으로 사료된다.

CT Images of a Malignant-Transformed Ovarian Mature Cystic Teratoma with Rupture: a Case Report

Po Chin Wang,Tsung Lung Yang,Huay Ben Pan 대한영상의학회 2008 Korean Journal of Radiology Vol.9 No.5

A malignant transformation or a tumor rupture is a rare complication of ovarian mature cystic teratoma (MCT). A tumor rupture in a malignant-transformed MCT has never been reported in the literature. We present the CT images of a 39-yearold woman showing a large, predominantly cystic mass in the lower abdomen, with fat-fluid-level ascites. A contrast-enhanced solid component, with regional discontinuity within the cystic lesion, is also demonstrated. The pathologic diagnosis of the ruptured MCT unveils the malignant transformation (squamous cell carcinoma) and mesenteric carcinomatosis.

Mathematical Analysis of the Parallel Packet Switch with a Sliding Window Scheme

Liu, Chia-Lung,Wu, Chin-Chi,Lin, Woei The Korea Institute of Information and Commucation 2007 Journal of communications and networks Vol.9 No.3

This work analyzes the performance of the parallel packet switch (PPS) with a sliding window (SW) method. The PPS involves numerous packet switches that operate independently and in parallel. The conventional PPS dispatch algorithm adopts a round robin (RR) method. The class of PPS is characterized by deployment of parallel low-speed switches whose all memory buffers run more slowly than the external line rate. In this work, a novel SW packet switching method for PPS, called SW-PPS, is proposed. The SW-PPS employs memory space more effectively than the existing PPS using RR algorithm. Under identical Bernoulli and bursty data traffic, the SW-PPS provided significantly improved performance when compared to PPS with RR method. Moreover, this investigation presents a novel mathematical analytical model to evaluate the performance of the PPS using RR and SW method. Under various operating conditions, our proposed model and analysis successfully exhibit these performance characteristics including throughput, cell delay, and cell drop rate.

Comparison of Models for the Prediction of Medical Costs of Spinal Fusion in Taiwan Diagnosis-Related Groups by Machine Learning Algorithms

Ching-Yen Kuo,Liang-Chin Yu,Hou-Chaung Chen,Chien-Lung Chan 대한의료정보학회 2018 Healthcare Informatics Research Vol.24 No.1

Objectives: The aims of this study were to compare the performance of machine learning methods for the prediction of themedical costs associated with spinal fusion in terms of profit or loss in Taiwan Diagnosis-Related Groups (Tw-DRGs) andto apply these methods to explore the important factors associated with the medical costs of spinal fusion. Methods: A dataset was obtained from a regional hospital in Taoyuan city in Taiwan, which contained data from 2010 to 2013 on patients ofTw-DRG49702 (posterior and other spinal fusion without complications or comorbidities). Naïve-Bayesian, support vectormachines, logistic regression, C4.5 decision tree, and random forest methods were employed for prediction using WEKA3.8.1. Results: Five hundred thirty-two cases were categorized as belonging to the Tw-DRG49702 group. The mean medicalcost was US $4,549.7, and the mean age of the patients was 62.4 years. The mean length of stay was 9.3 days. The lengthof stay was an important variable in terms of determining medical costs for patients undergoing spinal fusion. The randomforest method had the best predictive performance in comparison to the other methods, achieving an accuracy of 84.30%,a sensitivity of 71.4%, a specificity of 92.2%, and an AUC of 0.904. Conclusions: Our study demonstrated that the randomforest model can be employed to predict the medical costs of Tw-DRG49702, and could inform hospital strategy in terms ofincreasing the financial management efficiency of this operation.

Tamoxifen and the Risk of Parkinson’s Disease in Female Patients with Breast Cancer in Asian People: A Nationwide Population-Based Study

Chien-Tai Hong,Lung Chan,Chaur-Jong Hu,Chien-Min Lin,Chien-Yeh Hsu,Ming-Chin Lin 한국유방암학회 2017 Journal of breast cancer Vol.20 No.4

Purpose: Whether tamoxifen affects the risk of neurodegenerative disease is controversial. This nationwide population-based study investigated the risk of Parkinson’s disease (PD) associated with tamoxifen treatment in female patients with breast cancer using Taiwan’s National Health Insurance Research Database. Methods: A total of 5,185 and 5,592 female patients with breast cancer who did and did not, respectively, receive tamoxifen treatment between 2000 and 2009 were included in the study. Patients who subsequently developed PD were identified. A Cox proportional hazards model was used to compare the risk of PD between the aforementioned groups. Results: Tamoxifen did not significantly increase the crude rate of developing PD in female patients with breast cancer (tamoxifen group, 16/5,169; non-tamoxifen group, 11/5,581; p=0.246). Tamoxifen did not significantly increase the adjusted hazard ratio (aHR) for subsequently developing PD (aHR, 1.310; 95% confidence interval [CI], 0.605–2.837; p= 0.494). However, tamoxifen significantly increased the risk of PD among patients followed up for more than 6 years (aHR, 2.435; 95% CI, 1.008–5.882; p=0.048). Conclusion: Tamoxifen treatment may increase the risk of PD in Taiwanese female patients with breast cancer more than 6 years after the initiation of treatment.

Taiwanese Female Vegetarians Have Lower Lipoprotein-Associated Phospholipase A2 Compared with Omnivores

Chih-Wei Chen,Chin-Lon Lin,Chih-Ta Lin,Ying-Lung Lin,Tin-Kwang Lin 연세대학교의과대학 2011 Yonsei medical journal Vol.52 No.1

Purpose: Many studies supported that vegetarians have a lower risk of cardiac diseases and mortality, partly due to better blood pressure and serum cholesterol profiles. However, the inflammatory markers, especially lipoprotein-associated phospholipase A2 (Lp-PLA2), have not been well-studied. This study aimed to compare inflammatory markers and conventional risk factors between vegetarians and omnivores. Materials and Methods: One hundred and seventy-three vegetarians and 190 omnivores were studied. Fasting blood samples were obtained to compare levels of glucose, total cholesterol, triacylglycerol, high density lipoprotein (HDL) and low density lipoprotein (LDL) cholesterol, homocysteine, Lp-PLA2 activity, and high-sensitivity C-reactive protein (hs-CRP). Results: Vegetarians had higher serum levels of the following markers: hs-CRP (1.8 ± 3.4 vs. 1.2 1.8 mg/L, respectively; p = 0.05), homocysteine (9.39 ± 3.22 vs. 7.62 ± 2.41 μmol/L, respectively; p < 0.01), and triacylglycerol (96.91 ± 59.56 vs. 84.66 ± 43.24 mg/dL, respectively; p < 0.05). Vegetarians also had lower levels of Lp-PLA2 (18.32 ± 7.19 10-3 μmol/min/mL vs. 20.22 8.13 10-3 μmol/min/mL; p < 0.05), total cholesterol (180.62 ± 36.55 mg/dL vs. 192.73 ± 36.57 mg/dL; p < 0.01), LDL cholesterol (118.15 ± 32.8 vs. 126.41 ± 34.28 mg/dL; p < 0.05), and HDL cholesterol (55.59 ± 13.30 vs. 62.09 ± 14.52 mg/dL, p < 0.01). Multivariate analyses demonstrated that a vegetarian diet increases the chances for high serum hs-CRP and low Lp-PLA2 activity. Conclusion: In addition to lower total cholesterol,LDL-cholesterol, and HDL-cholesterol, Taiwanese female vegetarians have lower serum Lp-PLA2 activity but higher levels of hs-CRP, homocysteine, and triacylglyerol. It might be due to geographic differences of vegetarian diets, and further studies are needed.

이유기 흰쥐 소장 점막 유당분해효소에 대한 갑상선호르몬의 영향

장동경,진영주,이국래,김태호,이동호,정현채,송인성,김정룡 大韓消化器病學會 1998 大韓消化器病學會誌 Vol.31 No.6

Exendin-4 improves resistance to Listeria monocytogenes infection in diabetic db/db mice

Hsien Yueh Liu,Chih-Yao Chung,Wen-Chin Yang,Chih-Lung Liang,Chi-Young Wang,Chih-Yu Chang,Cicero Lee-Tian Chang 대한수의학회 2012 Journal of Veterinary Science Vol.13 No.3

The incidence of diabetes mellitus is increasing among companion animals. This disease has similar characteristics in both humans and animals. Diabetes is frequently identified as an independent risk factor for infections associated with increased mortality. In the present study, homozygous diabetic (db/db) mice were infected with Listeria (L.) monocytogenes and then treated with the anti-diabetic drug exendin-4, a glucagon-like peptide 1 analogue. In aged db/db mice, decreased CD11b+ macrophage populations with higher lipid content and lower phagocytic activity were observed. Exendin-4 lowered high lipid levels and enhanced phagocytosis in macrophages from db/db mice infected with L. monocytogenes. Exendin-4 also ameliorated obesity and hyperglycemia, and improved ex vivo bacteria clearance by macrophages in the animals. Liver histology examined during L. monocytogenes infection indicated that abscess formation was much milder in exendin-4-treated db/db mice than in the control animals. Moreover, mechanistic studies demonstrated that expression of ATP binding cassette transporter 1, a sterol transporter, was higher in macrophages isolated from the exendin-4-treated db/db mice. Overall, our results suggest that exendin-4 decreases the risk of infection in diabetic animals by modifying the interaction between intracellular lipids and phagocytic macrophages.