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박승욱 ( Cheng Xu Piao ),김태형 ( Tae Hyeung Kim ),양준호 ( Jun Ho Yang ),이효우 ( Xiao Yu Li ),하현철 ( Hyun Chul Ha ),정재훈 ( Jae Hun Jung ) 한국산업위생학회 2008 한국산업보건학회지 Vol.18 No.2
Bag-filter system has been widely used in industrial field to remove the particulate matters from the exhaust gas. The cylindrical type of bag-filter has been generally used. But it has many shortcomings. The reattachment of separated particles on the surface of bags could result in high pressure drop of bag-filter system and subsequent decrease of air flow rate since the cylindrical type bag-filter system should have the upward flow pattern. In addition, the supply of very high pressure pulse air jet to remove particulate matters on the surface of filter could result in a frequent rupture of bags. To overcome these shortcomings of the cylindrical type, the rectangular type was developed in the developed countries and imported to Korea. But, there was not many design data available to understand the mechanisms. Thus, the fundamental experiments were conducted in this study to get some ideas about the pulse jet cleaning of rectangular type bag filter system. The experimental factors are as follows; pulse distance, pulse duration, pulse interval, pulse pressure and pulse nozzle type. Experiments followed the factorial design method. With the shorter pulse distance, the distribution of pressure drops was relatively not uniform while the particulate removal efficiency was higher. With the longer duration of pulsing and the more number of pulse nozzle, the removal efficiency was higher and the pressure drop distribution was more uniform.
Oleifolioside B-mediated autophagy promotes apoptosis in A549 human non-small cell lung cancer cells
JIN, CHENG-YUN,YU, HAI YANG,PARK, CHEOL,HAN, MIN HO,HONG, SU HYUN,KIM, KYOUNG-SOOK,LEE, YOUNG-CHOON,CHANG, YOUNG-CHAE,CHEONG, JAEHUN,MOON, SUNG-KWON,KIM, GI-YOUNG,MOON, HYUNG-IN,KIM, WUN-JAE,LEE, JAI- Spandidos Publications 2013 International journal of oncology Vol.43 No.6
Yi‑Ju Ho,Hsiang‑Lung Cheng,Lun‑De Liao,Yu‑Chun Lin,Hong‑Chieh Tsai,Chih‑Kuang Yeh 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00
Background Ischemic stroke-reperfusion (S/R) injury is a crucial issue in the protection of brain function after thrombolysis. The vasodilation induced by ultrasound (US)-stimulated microbubble cavitation has been applied to reduce S/R injury through sonoperfusion. The present study uses oxygen-loaded microbubbles (OMBs) with US stimulation to provide sonoperfusion and local oxygen therapy for the reduction of brain infarct size and neuroprotection after S/R. Methods The murine S/R model was established by photodynamic thrombosis and thrombolysis at the remote branch of the anterior cerebral artery. In vivo blood flow, partial oxygen pressure ( pO2), and brain infarct staining were examined to analyze the validity of the animal model and OMB treatment results. The animal behaviors and measurement of the brain infarct area were used to evaluate long-term recovery of brain function. Results The percentage of blood flow was 45 ± 3%, 70 ± 3%, and 86 ± 2% after 60 min stroke, 20 min reperfusion, and 10 min OMB treatment, respectively, demonstrating sonoperfusion, and the corresponding pO2 level was 60 ± 1%, 76 ± 2%, and 79 ± 4%, showing reoxygenation. After 14 days of treatment, a 87 ± 3% reduction in brain infarction and recovery of limb coordination were observed in S/R mice. The expression of NF-κB, HIF-1α, IL-1β, and MMP-9 was inhibited and that of eNOS, BDNF, Bcl2, and IL-10 was enhanced, indicating activation of anti-inflammatory and anti-apoptosis responses and neuroprotection. Our study demonstrated that OMB treatment combines the beneficial effects of sonoperfusion and local oxygen therapy to reduce brain infarction and activate neuroprotection to prevent S/R injury.
Coal Chemical Looping Gasification for Syngas Generation Using an Iron-Based Oxygen Carrier
Guo, Qingjie,Cheng, Yu,Liu, Yongzhuo,Jia, Weihua,Ryu, Ho-Jung American Chemical Society 2014 INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH - Vol.53 No.1
<P>The chemical-looping gasification (CLG) of coal is a clean and effective technology for syngas generation. Sharing principles with chemical-looping combustion (CLC), CLG also uses oxygen carriers to transfer lattice oxygen to the fuel. Investigations into CLG with different O/C ratios are carried out in a fluidized bed reactor with steam used as the gasification–fluidization medium. The effect of the active component content of the oxygen carrier on the gas selectivity is performed, and reaction mechanisms between the Fe<SUB>2</SUB>O<SUB>3</SUB> oxygen carrier and coal with steam as the gasification agent are discussed. Moreover, we also assessed the reactivity of the CaO-decorated iron-based oxygen carrier particles in multicycle reactions. The carbon conversion efficiency is increased from 55.74 to 81% with increasing O/C ratio, whereas the content of H<SUB>2</SUB> first decreases and then increases. The addition of CaO can increase the carbon conversion efficiency and the gasification rate substantially and reduce the generation rate of H<SUB>2</SUB>S from 1.89 × 10<SUP>–3</SUP> to 0.156 × 10<SUP>–3</SUP> min<SUP>–1</SUP>. Furthermore, X-ray diffraction (XRD) images indicate that the CaO-decorated iron-based oxygen carrier particles were completely regenerated after six redox cycles. Finally, the peak fitting of gasification reaction rate curves is used to explore the reaction mechanism between coal char and the CaO-decorated iron-based oxygen carrier, indicating that the reactions in the CLG include three stages: the complex reactions involved an oxygen carrier, coal char, and steam; the gasification of coal char; and the reduction of Fe<SUB>3</SUB>O<SUB>4</SUB> to FeO. The two-segment modified random pore model (MRPM) fits the experiment data well.</P>
Shin, Seung Ho,Seo, Sang Gwon,Min, Soyun,Yang, Hee,Lee, Eunjung,Son, Joe Eun,Kwon, Jung Yeon,Yue, Shuhua,Chung, Min-Yu,Kim, Kee-Hong,Cheng, Ji-Xin,Lee, Hyong Joo,Lee, Ki Won American Chemical Society 2014 Journal of agricultural and food chemistry Vol.62 No.19
<P>In the present study, we aimed to investigate the antiobesity effect of CAPE in vivo, and the mechanism by which CAPE regulates body weight in vitro. To confirm the antiobesity effect of CAPE in vivo, mice were fed with a high fat diet (HFD) with different concentrations of CAPE for 5 weeks. CAPE significantly reduced body weight gain and epididymal fat mass in obese mice fed a HFD. In accordance with in vivo results, Oil red O staining results showed that CAPE significantly suppressed MDI-induced adipogenesis of 3T3-L1 preadipocytes. FACS analysis results showed that CAPE delayed MDI-stimulated cell cycle progression, thereby contributing to inhibit mitotic clonal expansion (MCE), which is a prerequisite step for adipogenesis. Also, CAPE regulated the expression of cyclin D1 and the phosphorylation of ERK and Akt, which are upstream of cyclin D1. These results suggest that CAPE exerts an antiobesity effect in vivo, presumably through inhibiting adipogenesis at an early stage of adipogenesis.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jafcau/2014/jafcau.2014.62.issue-19/jf405088f/production/images/medium/jf-2013-05088f_0006.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/jf405088f'>ACS Electronic Supporting Info</A></P>