濟州道 改良草地에 있어서 띠(Imperata cylindrica)의 季節的 年次的 變化

趙南棋,金翰琳,宋昌吉 제주대학교 1983 논문집 Vol.16 No.-

本 硏究는 濟州道 中山間地帶의 自然草地(Imperata cylindrica/Zoysia japonica type)를 開墾한 後 1 ha當 Dactylis glomerata 17kg, Festuca arundinacea 7kg, Lolium multiflorum 2kg, Trifolium repens 2kg의 導入牧草를 混播(28kg)하여 家畜放牧에 利用되고 있는(1977∼1982年) 改良草地를 對象으로하여, 띠(Imperata cylindrica)植生의 季節的ㆍ年次的變化過程을 調査한 結果를 要約하면 다음과 같다. 1. 每年 季節에 따르는 草長ㆍ收量ㆍ密度ㆍ被度 等 植生의 季節的 變化에 있어서는 秋期에 가장 優勢하였고, 春期에는 低調하게 나타났다. 2. 改良後 年度別 草長의 變化는 1年草地에서 34.26cm이었으나 점차 增加되어 6年草地에서는 49.35cm이었는데, 이 變化狀態의 回歸方程式은 y=-0.13x²+4.41x+28.50이었다. 3. 年數의 經過에 따르는 密度의 變化는 1年草地에서 0.76%였던 것이 年數가 지남에 따라 급격히 增加되어 6年草地에 이르러서는 32.97%로 나타나고 있는데, 이 變化를 y=0.10x²+0.32x-2.30의 回歸方程式으로 表示할 수 있었다. 4. 草地造成 以後 年次別 被度의 變化는 1年草地에서 1.05%, 2年 1.38%, 3年 2.46%, 4年 17.11%, 5年 27.56%, 6年草地에서 36.66%로 每年 增加(y=1.40x²-2.36x+1.39)되었다. 5. 收量의 年次的 變化는 1年草地에서 1.95kg이었으나 年數가 지남에 따라 점차 增加되어 6年草地에서는 1,107.35kg으로 나타났는데, 이 變化狀態를 y=29.11x²+53.52x-154.67로 表示할 수 있었다. This study was conducted to examine the yearly and seasonal changes of Imperata cylindrica on the improved pasture of the mountain districts around Mt. Halla in Cheju Island. For this study, the researcher had investigated for six years from 1977 to 1982 the improved pasture which had been used for grazing from 1977 to 1982. The pasture was reclaimed from native grassland. The mixed seeds of 17kgs' Datylis glomerata, 7kgs' Festuca arundinacea, 2 kgs' Lolium multiflorum and 2kgs' Trifolium repens were sowed per 1 ha. The results of this study are the following : 1. The seasonal changes of Imperata cylindrica : its length, weight, density and coverage are heighest in Autumn, and are lowest in Spring every year. 2. The yearly change in the length of Imperata cylindrica : its length is gradually increased from 34.26 cm in the first year after the reclaimation to 49.35 cm in the 6th year. This change can be represented by the regression equation, Y=-0.13x²+4.41x+28.50. 3. The yearly change in its density : its density is rapidly increased from 0.73% in the first year to 32.97% in the sixth year. The results of this change can be obtained with the regression equation, Y=0.10x²+0.32x-2.30. 4. The yearly change in its coverage : its coverage is increased year by year (1.05% in the 1st year, 1.38% in the 2nd year, 2.46% in the 3rd year, 27.56% in the 5th year, and 36.66% in the 6th year). This change can be calculated with regression equation, Y=1.40x²-2.36x+1.39. 5. The yearly change in its weight : the weight is also increased year after year from 1.95 kg in the first year after reclaimation to 1107.35kg in the sixth year. This change can be calculated with the regression equation of y=29.11x²+53.52x-154.67.

Minimize makespan of permutation flowshop using pointer network

Cho Young In,Nam So Hyun,Cho Ki Young,Yoon Hee Chang,Woo Jong Hun 한국CDE학회 2022 Journal of computational design and engineering Vol.9 No.1

During the shipbuilding process, a block assembly line suffers a bottleneck when the largest amount of material is processed. Therefore, scheduling optimization is important for the productivity. Currently, sequence of inbound products is controlled by determining the input sequence using a heuristic or metaheuristic approach. However, the metaheuristic algorithm has limitations in that the computation time increases exponentially as the number of input objects increases, and separate optimization calculations are required for every problem. Also, the heuristic such as dispatching algorithm has the limitation of the exploring the problem domain. Therefore, this study tries a reinforcement learning algorithm based on a pointer network to overcome these limitations. Reinforcement learning with pointer network is found to be suitable for permutation flowshop problem, including input-order optimization. A trained neural network is applied without re-learning, even if the number of inputs is changed. The trained model shows the meaningful results compared with the heuristic and metaheuristic algorithms in makespan and computation time. The trained model outperforms the heuristic and metaheuristic algorithms within a limited range of permutation flowshop problem.

Graves 병 환자에서 항갑상선제 투여에 의한 TSH 수용체 항체의 변동에 관한 연구 : 치료 용량 및 기간에 따른 차이 및 임상상과의 관계 its relation to dose and duration of treatment~and clinical features

이문호,조보연,문대혁,고창순,민헌기,서교일 대한내과학회 1986 대한내과학회지 Vol.30 No.3

We undertook a prospective study of 59 patients with Graves' disease in order to clarify the influence of antithyroid drug on the immunological indices and to determine the association of the changes of TSH receptor antibodies activities with drug dosage, duration of treatment and clinical features according to mode of antitbyroid drugs treatment. Patients were divided into two groups. High dose group included 28 patients and conventional dose group 31 patients. We measured TBII activities, antimicrosomal antibodies, and the size of goiter every 3 months, comparing them with clinical features and laboratory findings. TBII activities declined from R months until 9 months following drug treatment. Therafter no significant change of TBII activities were observed. Antimicrosomal antibodies showed the same pattern of change. There was no statistically significant difference of declining rate of TBII activities, antimicrosomal antibodies, and reduction of size of thyroid between two treatment groups. TBII activities fell into normal range in 15 patients among those 44 patients who had been followed for more than 9 months (8 high dose group, 7 conventional dose group). In those 15 patients, TBII activities and frequency of exophthalmos were less than those whose TBII activity did not normalized. We conclude that TSH receptor antibodies activities and antithyroid autoantibodies are diminished by antithyroid drug treatment in patients with Graves disease and there is no relationship between dose of drug and declining of TBII activities. We suggest that changing levels of TBII activities might be secondary phenomenon which can be achieved by control of thyroid function by antithyroid drug rather than direct immunosuppressive effect of antithyroid drug per se.

만성 화농성 중이염의 세균학적 고찰

조남순,이영훈,강기훈,최제환,송태현,이병돈,장혁순,강주원,김연준 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

Background and Objectives : Chronic suppurative otitis media is one of the frequent diseases in otolaryngologic field. It is important to choose of antibiotics in the management of infectious disease. But the organisms in infections have been changed and resistance to antibiotics has been grown as the development of antibiotics has been achieved. And so it has been necessary to recognize the changes of organisms and resistance in antibiotics. Our study was performed to identify the pathogens isolated from discharges in chronic otitis media and evaluate the antibiotic agents, to recognize the change of to resistance to·antibiotic agents and to use the appropriate anitiotics. Materials and Methods : Retrospectively, authors reviewed the backeriologic study of 114 cases of chronic suppurative otitis media who visited the Department of Otolaryngology, Soonchunhyang University in Seoul from Nov. 1996 to Oct. 1999 and analyzed 101 strains and its sensitivity test to various antibiotics. Result : In 93 cases in which pathogenic organism was isolated, single infection was 85 cases(91.4%) and mixed infection was 8 cases(8.6%). The most frequent pathogenic organism was Staphylococcus aureus(59.4%), Pseudomonas aeruginosa(13.9%), Providencia(4.8%), Alcaligenes(3.0%) and Streptococcus pneumoniae(2.9%) were the next. Methicilline-Resistance Staphylococcus aureus was 34 cases(57.6%) of Staphylococcus aureus. Staphylococcus aureus was sensitive to Vancomycin(96.7%), Trimethoprim-Sulfamethoxazole (57.6%), Cefuroxime(42.4%) and Ciprofloxacin(40.7%) but resistant to Penicillin(94.9%). Pseudomonas aeruginosa was sentitive Amikacin(100%), Ciprofloxacin(100%) and Gentamicin(67%). Conclusion : As MRSA recently was wide spread in community accquired infection as well as nosocomial infection, we must consider strict control of MRSA.

Determination of Diversity, Distribution and Host Specificity of Korean Laccaria Using Four Approaches

( Hae Jin Cho ),( Ki Hyeong Park ),( Myung Soo Park ),( Yoonhee Cho ),( Ji Seon Kim ),( Chang Wan Seo ),( Seung-yoon Oh ),( Young Woon Lim ) 한국균학회 2021 Mycobiology Vol.49 No.5

The genus Laccaria (Hydnangiaceae, Agaricales) plays an important role in forest ecosystems as an ectomycorrhizal fungus, contributing to nutrient cycles through symbiosis with many types of trees. Though understanding Laccaria diversity and distribution patterns, as well as its association with host plants, is fundamental to constructing a balanced plant diversity and conducting effective forest management, previous studies have not been effective in accurately investigating, as they relied heavily on specimen collection alone. To investigate the true diversity and distribution pattern of Laccaria species and determine their host types, we used four different approaches: specimen-based analysis, open database search (ODS), NGS analysis, and species-specific PCR (SSP). As a result, 14 Laccaria species have been confirmed in Korea. Results regarding the species distribution pattern were different between specimen-based analysis and SSP. However, when both were integrated, the exact distribution pattern of each Laccaria species was determined. In addition, the SSP revealed that many Laccaria species have a wide range of host types. This study shows that using these four different approaches is useful in determining the diversity, distribution, and host of ECM fungi. Furthermore, results obtained for Laccaria will serve as a baseline to help understand the role of ECM fungi in forest management in response to climate change.

β-Carotene과 알코올을 섭취한 쥐의 혈액 성분변화의 상관관계

고재웅,조만희,이상한,우기민,염윤기,김창세 순천향의학연구소 2000 Journal of Soonchunhyang Medical Science Vol.6 No.2

The study was carried out to investigate the effects of dietary carotenids and β-carotene on the hematological changes caused by alcohol administration into the rats. The results were analyzed using several statistical methods; SPSS computer program for measuring the mean values and standard deviations, one way ANOVA for the test of significance, Duncan method for post HOC multiple comparison, and Pearson method for measuring the correlation coefficient. The following are the conclusion from those statistical analysis. 1. ALB and TB were shown to have the most significant correlation among the blood compositions f개m the basic dietary groups. 2. BUN and CHO were shown to have the most positive correlation among those from the carrot-fed groups. 3. CA and AG were shown positively correlated, and CHO and IP negatively correlated, respectively among those from the cheese-fed groups. 4. AP was shown positively correlated among those from the alcohol-administrated groups. 5. CHO, CA and BUN were shown positively correlated, and CA was negatively correlated among those from the β-Carotene -fed groups. 6. TB and TP were not affected by the correlations between the blood composition from all the experimental groups.

濟州島 人工草地 植生의 經時的 變化에 관한 硏究 : 草種의 李節 및 年次的 變化 The Seasonal and Annual Changes in Species

金翰琳,趙南棋,宋昌吉 제주대학교 1981 논문집 Vol.13 No.-

本 硏究는 濟州道 改良牧草地에 있어서 草種組成의 季節 및 年次的 變動狀態를 調査한 結果이며 그 槪要는 다음과 같다. 1. 改良年度別 草種의 變動狀態는 1975年 草地에서 37種이었으나 年數가 經過함에 따라 種數가 增加되어 1980年 草地에서는 130種이었으며 每年 季節에 따르는 種의 數는 夏期에 가장 많았고 春期에는 種의 分布가 가장 적었다. 2. 改良年度別 生育型의 分布變動狀態는 1975年 草地에서 一年生 12種, 多年生 25種, 木本 1種이었으나,年數가 지남에 따라 每年 增加되어 1980年 草地에서는 一年生 42種, 多年生 88種, 木本 5種이었으며, 每年 季節에 따르는 生育型에 있어서는 一年生은 秋期에서, 多年生은 夏期에서 가장 많은 種이 分布되었고 木本雜草는 季節에 變化가 없었다. This study was conducted to investigate the seasonal and annual changes in species on the impoved pastures in Cheju Island. The results are as follows : 1. The annual changes in the number of intruding weed species were obsered. 33 weed species were found in 1975 and increased year after year to 127 species in 1980. The seasonal changes of species by year were also observed. In summer more species ranged than in any other seasons and the number of species growing in spring was found fewer than in other seasons. 2. The distributional changes in annual and perenial plant were brough on. 10 species of annual plant, 23 species of perennial plant, and one species of arbor were found in 1975 and increased respectively year by year to 44 species (annual plant), 86 species(perennial plant) and 5 species (arbor) in 1980. The seasonal changes in ecology by year showed a tendency that more species of annual plant ranged in autumn, and more perennial plants in summer than in any other season. But there is no change in the species of arbor.

中風病辨證診斷標準에 의한 臨床的 硏究

任長信,文祥官,高昌男,權正男,曺基湖,金永錫,裵亨燮,李京燮 경희대학교 1997 慶熙醫學 Vol.13 No.3

대장암종에서 암관련 유전자들의 Promoter Methylation과 암종 발생 및 진행과의 관게에 대한 연구

정동준,이정은,민영기,조성우,백무준,양승하,김의한,김창진 순천향대학교 교수학습개발센터 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

The colorectal corcinoma is one of the most common malignant tumor in Korea and its carcinogenic mechanism has not been elucidated exactly yet. So far, the most common carcinogenic mechanism has been known to be multiple genetic changes. But, the CpG island hypermethylation has been revealed to be one of the most important carcinogenic mechanism second to the genetic changes. The epigenetic changes characteristically imprint and transfer to the next generation without changes of nucleotide sequences. When the CpG island of promoter or 5'- exon 1 of a specific gene is methylated by DNA methyltrasferases (DNMTs), the gene expression is inhibited. Carcinogenic mechansisms by promoter methylation has been well known, but the progression of the cancer has not been elucidated yet. The molecular researches on the carcinogenic mechanisms largely depended on the tumor tissue containing various components of cell, due to difficulties in harvesting pure homogeneous tumor cells. Promoter methylatonof the cancer related genes as APc, hMLH2, p16, DAP-K and MGMT in 50 cases of sporadic colorectal carcinoma was studied. The pure normal colorectal epithelial cells, and cancer cells from superficial and deep invasive portion were harvested respectively by laser captured microdissection(LCM), and DNA was extracted from them. The promoter methylation was studied by methylation specific poymerase reaction (MSP) after bisulfite modification of the DNA and the expression of the genes by immunohistochemistry. The results suggests that promoter methylation of the cancer related genes are closely related with the colorectal carcinogenesis and it occurrs from early phase of carcinogenesis, progressing constantly to the late stage. And the promoter methylation of normal epithelial cells increased by age. The p15, known to be the genes related to hematologic malignancy, was closely related to the colorectal carcinoma as well.

Encephalo-duro-arterio-synangiosis(EDAS) using Occipital Artery in Children with Moyamoya Disease

Choi, In-Jae,Hong, Seok-Ho,Cho, Byung-Kyu,Wang, Kyu-Chang,Kim, Seung-Ki The Korean Neurosurgical Society 2005 Journal of Korean neurosurgical society Vol.38 No.6

Objective : Although an encephaloduroarteriosynangiosis procedure using the superficial temporal artery [STA-EDAS] is an effective indirect bypass method in children with moyamoya disease[MMD], there is still a need for an additional bypass operation that can cover the area of the posterior circulation. The goal of this study is to evaluate the efficacy of the EDAS procedure using the occipital arteries [OA-EDAS]. Methods : From August 2003 to April 2004, We performed OA-EDAS in sixteen patients with MMD who have a circulatory insufficiency in the territory of the posterior cerebral artery[PCA]. The medical records were reviewed retrospectively. The surgical outcomes, including the changes in neurological status and imaging studies, with the degree of neovascularization on the cerebral angiogram, and the hemodynamic changes on single-photon emission computed tomography[SPECT], were analyzed. Results : These 16 children consisted of 5 boys and 11 girls aged 2 to 9 years. The clinical outcome of their PCA symptoms, such as visual transient ischemic attacks[TIAs] or visual field defect, was favorable in 14 patients of 16. Nine patients of 11 who underwent follow up magnetic resonance imaging[MRI] showed favorable MRI changes. On angiogram most of the patients exhibited good or fair revascularization of the PCA territory [7 of 8]. The hemodynamic changes on SPECT in the PCA territory after surgery showed improved vascular reserve in 13 of the 16 territories. Conclusion : OA-EDAS is a safe and efficacious revascularization procedure in patients with MMD who have compromised cerebral perfusion in PCA territory, or with visual TIAs.