Metal-organic frameworks with high working capacities and cyclic hydrothermal stabilities for fresh water production

Kim, S.I.,Yoon, T.U.,Kim, M.B.,Lee, S.J.,Hwang, Y.K.,Chang, J.S.,Kim, H.J.,Lee, H.N.,Lee, U.H.,Bae, Y.S. Elsevier 2016 CHEMICAL ENGINEERING JOURNAL -LAUSANNE- Vol.286 No.-

In this work, we evaluated the working capacities of eight hydrothermally stable metal-organic frameworks (MOFs) for water adsorption under typical humidity conditions in three representative dry regions. Remarkably, three MIL-100(M) materials (M=Cr, Al, and Fe) and MIL-101(Cr) exhibited very high working capacities for medium and high humidity conditions due to their large surface areas. All of the MOFs consisting of only M<SUP>III</SUP> sites (MIL-101(Cr), MIL-100(Cr), and MIL-100(Al)) showed good cyclic water adsorption/desorption performances and good hydrothermal stabilities. Due to the presence of Fe<SUP>II</SUP> sites formed during activation at 250<SUP>o</SUP>C, MIL-100(Fe) showed a considerable decrease in its water adsorption isotherm during the 2nd cycle although almost unchanged water uptakes were observed in the following cycles. When MIL-100(Fe) was activated at 150<SUP>o</SUP>C (MIL-100(Fe)_150) to prevent formation of Fe<SUP>II</SUP> sites, the sample showed good cyclic adsorption/desorption performance and good hydrothermal stability. Considering the high working capacities, cyclic adsorption/desorption behaviors, and good hydrothermal stabilities, MIL-101(Cr), MIL-100(Cr), MIL-100(Al) and MIL-100(Fe)_150 are promising adsorbents for producing drinking water in dry regions with medium or high humidity conditions during the night.

참깨의 모자이크 증상에서 분리한 수박${\cdot}$모자이크 바이러스에 관한 연구

장무웅,이창은,Chang M.U.,Lee C.U. 한국응용곤충학회 1980 한국식물보호학회지 Vol.19 No.4

참깨, 호박, 오이의 모자이크 증상주에서 전자현미경 및 즙액접종에 의하여 분리한 바이러스에 대하여 다음과 같은 결과를 얻었다. 1. 본 바이러스를 즙액접종 하였을 때 P. vutgaris, P. sativum, S. indicum, C. melo, C. maxima, C. pepo는 전신감염, C. amaranticolar는 국부감염 되었다. 2. 본 바이러스는 M. persicae로 쉽게 전반되었고, 종자전염은 하지 않았다. 9. 조즙액중의 물리성은 내열성이 $55\~60^{\circ}C$(10분), 희석성이 $10^{-3}\~10^{-4}$, 내보존성이 $10\~14$일$(22^{\circ}C)$이었다. 4. 본 바이러스의 형태는 길이 $750\~800nm$의 사상립자이고, 본 바이러스의 감염에 의해 세포질내에서 세포질봉입체가 만들어진다는 것이 확인되었다. 5. 본 바이러스에 감염된 S. indicum, C. amaranticolor의 병엽초박절편을 전자현미경으로 관찰하였던바, 각종세포의 세포질내에 사상립자가 병행배열 또는 산재해 있고, 또 사상립자와 함께 반드시 세포질내입체(pinwheel, boundles, laminated aggregates)가 확인되었다. 6. 이상의 결과를 종합해서 참깨 모자이크병의 병원바이러스를 Watermelon mosaic virus(WMV)로 동정하였다. This paper deals with the studies on the occurence of a new virus disease of sesame and the identification of the causal virus. The virus disease of sesame has been regarded as a widespread disease in the sesame-growing areas in the southern part of Korea. The disease was found to be caused by watermelon mosaic virus (WMV). During the years since 1978, stunting of sesame plants, with yellow mosaic, necrotic spot, and malformation, were collected from 17 different places. Virus isolates from 27 out of 32 samples were identified as WMV. Natural infection of squash, pumpkin, cucumber, and watermelon by WMV as well as sesame was proved. The virus is inactivated at temperatures of 55 to $60^{\circ}C$, at dilution of $10^{-3}\;to\;10^{-4}$, and in the aging of 10 to 14 days at about $20^{\circ}C$. Sesame, Chenopodium amaranticelor, pea, bean, as well as many plants of the Cucurbitaceae, are susceptible to the sesame-isolates of WMV. In negatively stained preparations, particles of the virus appear under the electron microscope as flexible filaments of about $750\~800nm$ in length. Cylindrical inclusions and virus particles were found in the cytoplasm of mesophyll cells by ultra-thin sections of WMV infected tissues.

폐쇄 핵 젖소집단에서 IVEP수준과 육종계회게 의한 선발반응과 근친계수

이광전,김정언,강민식,조광현,장길원,최현준 한국동물자원과학회 2000 한국축산학회지 Vol.42 No.2

This study was carried out for the aim of solving the selection response on nucleus herds in dairy cattle by using the Multiple Ovulation Embryo Transfer(MOET), coupled with adapting In Vitro Embryo Production(IVEP), and settled down the nine kinds of hierachical mating plans according to the number of sires and dams, and did simulation for breeding schemes and IVEP levels. The results obtained were as follows ; 1. The annual rate of inbreeding coefficients were decreased according to increasing the number of sires and dams. It was low in the mating plan with many sires and dams, when the mating ratios of dam to sire are equal. These trends were similar to the juvenile, adult and progeny testing schemes. 2. The annual rate of selection response was high as increasing IVEP levels and the number of sires and dams. 3. The annual rate of selection response was the highest in the case of adult scheme and was the lowest in the case of progeny test scheme, regardless of mating plans and IVEP levels. 4. The rate of selection responses in the low IVEP level with many sires and dams were similar to those in the high IVEP level with few sires and dams, so if we would increase IVEP levels, the number of sires and dams and the herd sizes would be decreased, this practice would be advantageous for making nucleus dairy herds. 5. In cult scheme with medium IVEP level, it was expected that the cumulative selection response amounted to one and more standard deviation units in 10 years and to two standard deviation units in 20 years.

Peroxiredoxin II promotes hepatic tumorigenesis through cooperation with Ras/Forkhead box M1 signaling pathway

Park, Y-H,Kim, S-U,Kwon, T-H,Kim, J-M,Song, I-S,Shin, H-J,Lee, B-K,Bang, D-H,Lee, S-J,Lee, D-S,Chang, K-T,Kim, B-Y,Yu, D-Y Macmillan Publishers Limited 2016 Oncogene Vol.35 No.27

<P>The current study was carried out to define the involvement of Peroxiredoxin (Prx) II in progression of hepatocellular carcinoma (HCC) and the underlying molecular mechanism(s). Expression and function of Prx II in HCC was determined using H-ras(G12V)-transformed HCC cells (H-ras(G12V)-HCC cells) and the tumor livers from H-ras(G12V)-transgenic (Tg) mice and HCC patients. Prx II was upregulated in H-ras(G12V)-HCC cells and H-ras(G12V)-Tg mouse tumor livers, the expression pattern of which highly similar to that of forkhead Box M1 (FoxM1). Moreover, either knockdown of FoxM1 or site-directed mutagenesis of FoxM1-binding site of Prx II promoter significantly reduced Prx II levels in H-ras(G12V)-HCC cells, indicating FoxM1 as a direct transcription factor of Prx II in HCC. Interestingly, the null mutation of Prx II markedly decreased the number and size of tumors in H-ras(G12V)-Tg livers. Consistent with this, knockdown of Prx II in H-ras(G12V)-HCC cells reduced the expression of cyclin D1, cell proliferation, anchorage-independent growth and tumor formation in athymic nude mice, whereas overexpression of Prx II increased or aggravated the tumor phenotypes. Importantly, the expression of Prx II was correlated with that of FoxM1 in HCC patients. The activation of extracellular signal-related kinase (ERK) pathway and the expression of FoxM1 and cyclin D1 were highly dependent on Prx II in H-ras(G12V)-HCC cells and H-ras(G12V)-Tg livers. Prx II is FoxM1-dependently- expressed antioxidant in HCC and function as an enhancer of Ras(G12V) oncogenic potential in hepatic tumorigenesis through activation of ERK/FoxM1/cyclin D1 cascade.</P>

거세한우의 도체형질에 대한 유전모수 추정

윤호백,김시동,나승환,장은미,이학교,전광주,이득환 한국동물자원과학회 2002 한국축산학회지 Vol.44 No.4

1998년도부터 2001년도까지 실시한 한우 후대검정에서 공시된 후보종모우들에 대한 근친도를 조사해 본 결과, 대부분의 종모우들은 근친되지 않고 있어 한우 종모우 집단은 아직 non-inbred 집단으로 간주해도 무방할 것으로 사료되었다. 하지만 많은 개체들간에 혈연관계가 있는 것으로 조사되어 앞으로 근친도가 크게 상향될 것으로 예상되기 때문에 농가에서 보다 계획적인 정액 선택을 통한 교배가 권장된다. 또한 거세 검정우 1262두로부터 조사된 도체성적들에 대한 유전모수를 선형모형하에서 REML 방법으로 추정된 결과와 근내지방도를 범주형자료로 간주하여 Gibbs sampling 방법으로 추정한 결과, 보다 다소 높게 추정되었으며 GS 방법에 의한 추정치가 REML 방법에 의한 추정치보다 높게 추정되었다. 특히 근내지방도에 대한 유전력 추정치는 GS 방법에서 0.74으로 아주 고도의 유전력을 갖는 것으로 추정되어 근내지방도에 대한 개량의 용이함을 제시하였다. 또한 근내지방도와 등지방두께 간에는 0.46의 유전상관을 갖는 것으로 추정되었으며 근내지방도와 출하시 체중간에는 -0.44의 부의상관을 갖는 것으로 추정되었다. 반면에 도체율과 근내지방도간에는 -0.72의 강한 부의상관을 갖는 것으로 추정되었는데 도체율에 대한 변이가 상당히 낮은 변이계수를 고려할 때 추정치에 대한 신뢰도가 낮을 것으로 예상되었다. 종모우의 육종가에 대한 추정방법간의 상관은 다소 낮을 것으로 예상되기 때문에 이에 대한 연구가 필요한 것으로 사료된다. The data were consisted of 1,262 records for carcass traits observed at Hanwoo steers from 1998 to 2001 at Namwon and Deakwanryung branch of National Livestock Research Institute, Rural Development Administration. Pedigrees of young bulls were traced back to search for magnifying inbreeding. Genetic parameters for carcass traits with Gibbs sampling in a threshold animal model were compared to estimates with REML algorithm in linear model. As the results, most of bulls were not inbred and sire pedigree group was non-inbred population. However, most of the bulls fell in some relationship with each other. Heritability estimates as fully posterior means by Gibbs samplers in threshold model were higher than those by REML in linear model. Furthermore, these estimates in threshold model using GS showed higher estimates than estimates using tested young bulls in previous study and same model. Heritability estimate by GS for marbling score was 0.74 and genetic correlation estimate between marbling score and body weight at slaughter was -0.44. Further study for correlation of breeding values between REML algorithm in linear model and Gibbs sampling algorithm in threshold model was needed.

Stereotactic radiosurgery for primary and metastatic sarcomas involving the spine.

Chang, U K,Cho, W I,Lee, D H,Kim, M S,Cho, C K,Lee, S Y,Jeon, D G M. Nijhoff ; Kluwer Academic Publishers 2012 Journal of neuro-oncology Vol.107 No.3

<P>The treatment for spinal sarcomas is difficult due to inadequate surgical margin and an inability to deliver high dose radiation. Advanced technology of stereotactic radiosurgery (SRS) enabled higher biological effective doses of radiation to be delivered to spinal sarcomas by hypofractionation method. The authors evaluated local control rate following SRS for primary and metastatic spinal sarcomas. Thirty-two spinal sarcomas (10 primary tumors, 22 metastatic tumors) in 27 patients were treated by SRS from November 2002 to September 2009. Patients were assessed for pain status, neurological status and radiological response by regular follow-up. Overall survival and local progression-free survival were calculated and prognostic factors were sought. Median tumor volume was 18.6 ml. Radiation doses to the tumor margins ranged from 16 to 45 Gy in one to three fractions, and the median single session equivalent dose was 21.8 Gy. Follow-up ranged from 4 to 68 months (median, 22 months). Overall median survival was 29 months and no related prognostic factors were identified. During follow-up, pain was controlled in 89.3% (25/28) lesions at 6 months, in 68.2% (15/22) at 1 year, and in 61.5% (8/13) at 2 years. Tumor volume was found to be significantly related to post-SRS pain control rate. Radiological evaluation showed that local control was maintained in 96.7% (29/30) lesions at 6 months, in 78.3% (18/23) at 1 year, and in 76.9% (10/13) at 2 years. Radiation dose and tumor volume were found to be related to radiological control at 24 months following SRS. Nine cases developed recurrence between 2 and 33 months, median local progression-free survival was 23 months. Age was found to be predictive of local progression-free survival (P = 0.009). SRS proved to be an effective modality for the local control of primary and metastatic spinal sarcomas, and age was significantly related to local recurrence.</P>

Cymbidium mild mosaic virus의 분리동정

Chang M. U.,Doi Y.,Yora K. 한국응용곤충학회 1978 한국식물보호학회지 Vol.17 No.3

Cymbidium의 mild mosaic 병주로부터 각종 초본식물에 즙액접종되는 소구형 바이러스를 분리하여 다음과 같은 결과를 얻었다. 1. 본 바이러스를 즙액접종하였을 때 C. amaranticlor, C. quinoa, Cymbidium spp., Dianthus caryophyllus는 전신감염, C.ficifolium, Gomphrean globosa는 국부감염되었다. 2. 본 바이러스는 Myzus persicae로 전반되지 않고, 영양번식기관에 의하여 전반되었다. 3. 조즙액중의 불활성화한계는 내열성이 $90^{\circ}C$ (10분)이고 내희석성이 $10^{-6}$, 내보존성이 60일 $(20^{\circ}C)$이였다. 4. 본 바이러스는 C. amaranticolor병엽을 동결후, chlorform으로 청등하여 분획원심분리와 sucrose density gradient 원심분리법으로 순화하였다. 5. 순화시료의 자외선흡수곡선은 최고 261nm, 최저 243nm이고 260/280=1.72, 최고/최저=1.26의 핵단백에 의한 흡수곡선을 나타냈다. 침강계수는 $S_{20,w}=126$의 수치가 얻어졌다. 6. 本 바이러스의 항혈청은 침강반응혼합법에 의해 2,025배의 역가를 나타냈고, 한천내확산법에 의한 시험에서 CarMV와 혈청학적관계가 있는 것으로 나타났다. 7. 本 바이러스의 형태는 직경 약 28nm의 소구형(다면체) 입자이고, empty particles도 소수 관찰되었다. 5. 본 바이러스에 감염된 C. amaranticolor, C. ficifolium, Cymbidium spp.의 병엽초박절편을 전자현미경으로 관찰하였든 바, 각종 세포의 세포질, 액포 및 도관내에 소구형 입자가 산재 또는 집괴의 소재양식으로 확인되었다. 9. 이상의 결과를 종합해서 본 바이러스를 Cymbidium mild mosaic virus로 명명한다. A virus named Cymbidium mild mosaic virus(Cy MMV), was mechanically transmitted to Chenopodium amaranticolor from the leaves of Cymbidium with mild mosaic symptoms. The virus was cultured in C. amaranticolor, in which it produced local chlorotic and ring spots, followed by systemic vein clearing with distortion. CyMMV infected 7 out of 35 species of plants. In C. amaranticolor juice infectivity was lost by heating at $90^{\circ}C$ for 10 miuntes, and by aging at$20^{\circ}C$ for 60 days, and by diluting at $10^{-6}$ when bioassayed on C. amaranticolor. CyMMV was not transmitted by Myzus persicae. The virus was purified after clarification of homogenized C. amaranticolor leaf tissues with chloroform, by differential centrifugation followed by sucrose density gradient centrifugation. Electron microscopic examination of purified preparation showed spherical particles of 28nm in diameter. The UV absorption spectrum of purified preparation was typical of u nucleoprotein (max. at 261nm. min. at 243nm), and showed 260/280=1.72 and max/min=1.26. The value of the sedimentation coefficient of the virus was S20.w=126. In gel-diffusion tests, CyMMV antiserum reacted with CarMV, but not with any of four other viruses (BBWV, CRSV, CMV, TBRV) having similar particles and properties in vitro. In ultra-thin sections of CyMMV infected tissues, a large number of virus particles were found in the cytoplasm of mesophyll cells and in xylem vessels.

Study of the baryon–antibaryon low-mass enhancements in charmless three-body baryonic <i>B</i> decays

Wang, M.-Z.,Abe, K.,Abe, K.,Aihara, H.,Asano, Y.,Aulchenko, V.,Aushev, T.,Bahinipati, S.,Bakich, A.M.,Bedny, I.,Bitenc, U.,Bizjak, I.,Bozek, A.,Brač,ko, M.,Brodzicka, J.,Browder, T.E.,Chang, M.-C Elsevier 2005 Physics letters: B Vol.617 No.3

<P><B>Abstract</B></P><P>The angular distributions of the baryon–antibaryon low-mass enhancements seen in the charmless three-body baryonic <I>B</I> decays <SUP>B+</SUP>→pp¯<SUP>K+</SUP>, <SUP>B0</SUP>→pp¯KS0 and <SUP>B0</SUP>→pΛ¯<SUP>π−</SUP> are reported. A quark fragmentation interpretation is supported, while the gluonic resonance picture is disfavored. Searches for the <SUP>Θ+</SUP> and <SUP>Θ++</SUP> pentaquarks in the relevant decay modes and possible glueball states G with 2.2 GeV/<SUP>c2</SUP><<SUB>Mpp¯</SUB><2.4 GeV/<SUP>c2</SUP> in the pp¯ systems give null results. We set upper limits on the products of branching fractions, B(<SUP>B0</SUP>→<SUP>Θ+</SUP>p¯)B(<SUP>Θ+</SUP>→pKS0)<2.3×<SUP>10−7</SUP>, B(<SUP>B+</SUP>→<SUP>Θ++</SUP>p¯)B(<SUP>Θ++</SUP>→p<SUP>K+</SUP>)<9.1×<SUP>10−8</SUP>, and B(<SUP>B+</SUP>→G<SUP>K+</SUP>)B(G→pp¯)<4.1×<SUP>10−7</SUP> at the 90% confidence level. The analysis is based on a 140 fb<SUP>−1</SUP> data sample recorded on the ϒ(4S) resonance with the Belle detector at the KEKB asymmetric energy <SUP>e+</SUP><SUP>e−</SUP> collider.</P>

A search for the rare leptonic decays ^B+→^μ+_νμ and ^B+→^e+_νe

Satoyama, N.,Abe, K.,Adachi, I.,Aihara, H.,Anipko, D.,Bakich, A.M.,Barberio, E.,Bedny, I.,Belous, K.,Bitenc, U.,Bizjak, I.,Bondar, A.,Bozek, A.,Brač,ko, M.,Browder, T.E.,Chang, M.-C.,Chang, P.,Ch Elsevier 2007 Physics letters: B Vol.647 No.2

<P><B>Abstract</B></P><P>We present a search for the decays <SUP>B+</SUP>→<SUP>μ+</SUP><SUB>νμ</SUB> and <SUP>B+</SUP>→<SUP>e+</SUP><SUB>νe</SUB> in a 253 fb<SUP>−1</SUP> data sample collected at the ϒ(4S) resonance with the Belle detector at the KEKB asymmetric-energy <I>B</I> factory. We find no significant evidence for a signal and set 90% confidence level upper limits of B(<SUP>B+</SUP>→<SUP>μ+</SUP><SUB>νμ</SUB>)<1.7×<SUP>10−6</SUP> and B(<SUP>B+</SUP>→<SUP>e+</SUP><SUB>νe</SUB>)<9.8×<SUP>10−7</SUP>.</P>

Study of Ωc0 and Ωc∗0 baryons at Belle

Solovieva, E.,Chistov, R.,Adachi, I.,Aihara, H.,Arinstein, K.,Aushev, T.,Bakich, A.M.,Balagura, V.,Bitenc, U.,Bondar, A.,Brač,ko, M.,Brodzicka, J.,Browder, T.E.,Chang, P.,Chen, A.,Cheon, B.G.,Cho Elsevier 2009 Physics letters: B Vol.672 No.1

<P><B>Abstract</B></P><P>We report results from a study of the charmed double strange baryons Ωc0 and Ωc∗0 at Belle. The Ωc0 is reconstructed using the Ωc0→<SUP>Ω−</SUP><SUP>π+</SUP> decay mode, and its mass is measured to be (2693.6±0.3−1.5+1.8) MeV/<SUP>c2</SUP>. The Ωc∗0 baryon is reconstructed in the Ωc0γ mode. The mass difference <SUB>MΩc∗0</SUB>−<SUB>MΩc0</SUB> is measured to be (70.7±0.9−0.9+0.1) MeV/<SUP>c2</SUP>. The analysis is performed using 673 fb<SUP>−1</SUP> of data on and near the ϒ(4S) collected with the Belle detector at the KEKB asymmetric-energy <SUP>e+</SUP><SUP>e−</SUP> collider.</P>