한우 Band 3 및 CHS 유전병의 분자유전학적 기초연구

정행진,유성란,상병찬,이준헌 충남대학교 농업과학연구소 2005 농업과학연구 Vol.32 No.1

Many bovine genetic diseases are currently unidentified in Korea because of the relatively low monitoring systems in the livestock farms. The molecular detection system using PCR-RFLP of two genetic diseases, namely Band 3 (Erythrocyte Membrane Protein Band Ⅲ) and CHS (Chediak-Higashi Syndrome), have been identified in Japan and used for screening large number of cattle whether each individual has the genetic disease or not. Using the 22 unrelated Korean cattle (Hanwoo) individuals, molecular detection system based on PCR-RFLP have been investigated, which can be distinguishable carriers for the genetic diseases. Even though we could not found the causative mutations for two genetic diseases, the PCR-RFLP techniques used in this study are very valuable for the screening the genetics diseases in Korean cattle, especially for the proven or candidate bulls.

자궁경부암 병기판정 기초검사시 새로운 보조방법으로서 고주파 질식 초음파의 가치

유희석,이은주,장기홍,권혁찬,양정인,김행수,오기석 아주대학교 의과학연구소 1996 아주의학 Vol.1 No.1

To investigate the efficacy of endoluminal ultrasound system (EUS) as a surrogate for high frequency transvaginal ultrasonography and as an optional baseline study in determining parameirial and stromal invasion of early stage cervical cancer, 52 women suspected of cervical cancer underwent EUS. A 12 MHz endoscopic probe was employed to radially scan the cervix for possible lesions suspected to be invasive cancer during a period of 6 months from Feb. 1 to July 1, 1995. Patients also underwent magnetic resonance imaging (MRI) and/or computerized tomography (CT) as a routine mode of baseline study, and were clinically staged by 3 independent physicians specializing in Obstetrics and Gynecology at the Department of Obstetrics and Gynecology, School of Medicine, Ajou University, Suwon, Korea. Thirty one patients subsequently received surgery appropriate for the stage of the disease and the final pathology findings were compared with the results of clinical staging, EUS, MRI/CT by regression analysis. The results showed that there was statistically significant correlation between MRI/CT and pathology (r=0.660, p<0.02), between EUS and pathology (r=0.803, p<0.01), and between clinical staging and pathology (r=0.825, p<0.01). It is concluded that there was significant statistical correlation t>etween EUS, MRI/CT, clinical staging and pathology, but the question remained as to the statistical superiority of EUS over MRI/CT with regard to parametrial invasion and stromal invasion depth assessment. Finally, EUS is useful as an alternative optional diagnostic tool in the baseline study of cervical cancer.

Prevalence of Barrett’s Esophagus Remains Low in the Korean Population: Nationwide Cross-Sectional Prospective Multicenter Study

Lee, In Seok,Choi, Suck Chei,Shim, Ki Nam,Jee, Sam Ryong,Huh, Kyu Chan,Lee, Jun Haeng,Lee, Kwang Jae,Park, Hyung Seok,Lee, Yong Chan,Jung, Hoon Yong,Park, Hyo Jin Springer-Verlag 2010 Digestive diseases and sciences Vol.55 No.7

Clinical and Angiographic Outcomes of Drug-Eluting Stents Implantation in Patients with End-Stage Renal Disease.

Chan Hyun Lee,Chul Kim,Eun Jung Kim,Bo Yeon Kim,Bo Yeon Kim,Hye-Sun Seo,Yoon Haeng Cho,Nae Hee Lee 순천향대학교 순천향의학연구소 2008 Journal of Soonchunhyang Medical Science Vol.14 No.2

Background : Percutaneous coronary intervention (PCI) on end stage renal disease (ESRD) patients has remained controversial because of exclusion of dialysis patients from major clinical trials. This study was designed to evaluate the clinical and 6-month angiographic outcomes of Drug eluting stent (DES) implantation in patients with ESRD. Methods : From June 2004 to February 2006, 49 dialysis patients who underwent drug stent implantation at 72 de no lesions were analyzed. Angiographic end points were binary in segment restenosis at 6 months after the index procedure and late luminal loss. Clinical endpoints were death and all clinical events in-hospital and during the follow-up period. Results : As risk factors, hypertension(81.6%) and Diabetes mellitus(73.5%)are very frequently observed. The patients tend to have multi-vessel disease. For 49 patients, 72 lesions were treated. Angiographic follow up was completed in 33 of 49 patients(67.3 %), who had 50 of 72 lesions (69.4%). Binary in segment restnosis occurred in 7 lesions(Sirolimus eluting stent(SES) group: 5/36, Paclitaxel eluting stent(PES) group: 2/14) and the restenosis rate was 14.0%. During the mean 15.5±9.6 month follow-up duration, 6 patients died (12.2 %). Major acute cardiac event (MACE) rate was 18.4% (9 of 49 patients). Major adverse cardiac events free survival rate at 18 month was 81.6 %. Conclusions : We found that DES is effective in reducing restenosis and Target lesion revascularization (TLR) in this population. Considering that DES does not reduce the risk of death in ESRD patients compared with normal renal function patients, more aggressive disease modifying strategies should be required in current DES era.

Multiple pathways of crystal nucleation in an extremely supersaturated aqueous potassium dihydrogen phosphate (KDP) solution droplet

Lee, Sooheyong,Wi, Haeng Sub,Jo, Wonhyuk,Cho, Yong Chan,Lee, Hyun Hwi,Jeong, Se-Young,Kim, Yong-Il,Lee, Geun Woo National Academy of Sciences 2016 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.113 No.48

<P>Solution studies have proposed that crystal nucleation can take more complex pathways than previously expected in classical nucleation theory, such as formation of prenucleation clusters or densified amorphous/liquid phases. These findings show that it is possible to separate fluctuations in the different order parameters governing crystal nucleation, that is, density and structure. However, a direct observation of the multipathways from aqueous solutions remains a great challenge because heterogeneous nucleation sites, such as container walls, can prevent these paths. Here, we demonstrate the existence of multiple pathways of nucleation in highly supersaturated aqueous KH2PO4 (KDP) solution using the combination of a containerless device (electrostatic levitation), and in situ micro-Raman and synchrotron X-ray scattering. Specifically, we find that, at an unprecedentedly deep level of supersaturation, a high-concentration KDP solution first transforms into a metastable crystal before reaching stability at room temperature. However, a low-concentration solution, with different local structures, directly transforms into the stable crystal phase. These apparent multiple pathways of crystallization depend on the degree of supersaturation.</P>

Oncogenic role of Rab25 in MMTV-PyMT breast cancer model

Chan Yang Uhm,Haeng Dueng Jeong,Kwang H. Kim,Sung Hee Kim,Ye Jin Cho,Mi Na Lee,Bu Hyun Lee,Yu Ra Lee,Su Min Heo,Na Kyum Lee,Ji Seon Kim,Dong Hun Jeon,Ki Taek Nam 한국실험동물학회 2022 한국실험동물학회 학술발표대회 논문집 Vol.2022 No.1

A Simple Cost Analysis of Host ID-LOC Separating protocol using SDN Features

Lee, Chan-Haeng,Choi, Chang-Won The Korea Internet of Things Society 2016 한국사물인터넷학회 논문지 Vol.2 No.4

The IP address used in the Internet has the role of both identifier and locator to bind a host and the application, however, this binding restricts some functions such as mobility and multi-homing. As a result, we suggested a host ID-LOC separation protocol using DHT with SDN features. The proposed scheme is a network-based scheme, and uses IPv6 addresses. The underlying network is partitioned into Host Identity domain and IP domain for identifiers and locators. In this paper, we present a simple cost model for analyzing both the proposed scheme and one of the previous works, the MOFI. The result of cost analysis shows better performance of the proposed scheme.

Isolation and Identification of Yeasts from Rotten Trees

Chan-Haeng LEE,Yu-Jeong LEE,Myoung-Dong KIM 한국생물공학회 2022 한국생물공학회 학술대회 Vol.2022 No.9

그들은 왜 빈센트 친을 죽였을까?

이찬행 ( Lee Chan Haeng ) 역사문제연구소 2016 역사문제연구 Vol.20 No.1

The murder of Vincent Chin is representative of a hate crime against Asian Americans. Chin was killed by two white men : Ronald Ebens, a foreman at Chrysler automobile plant in Detroit, and his step-son Michael Nitz after a barroom quarrel at a strip bar in Detroit in 1982. Chin went to the bar with his friends to celebrate his upcoming wedding but he was violently beaten to death by the two whites who misrecognized Chin as a person of Japanese descent. This article examines why they brutally killed the Chinese American. Asian Americans had to suffer anti-Asian sentiment and violence after they entered the United States in the mid-nineteenth century. The murder of Chin is modern-day violence against Asian Americans. However, the tragedy was also caused by the dynamics of race, gender, and class. This article argues that the Asian American man was killed because the two white males felt deprived of their exclusive rights to white women when Chin was consuming a white dancer`s sexual attention. It also maintains that Chin was murdered by the two white workers who felt that Japanese imports displaced them from their rightful place of employment.

미국 우파에 대한 역사서술의 궤적

이찬행 ( Chan-haeng Lee ) 한국서양사학회 2016 西洋史論 Vol.0 No.129

본 논문은 한때 주변적인 존재로 폄하된 미국의 우파가 20세기 후반 미국 정치를 지배하는 데 성공하게 되는 과정을 다룬 다양한 연구들의 궤적을 살펴본다. 첫째, 리처드 호프스태터로 대변되는 합의학파(Consensus School)는 1950년대 중후반에서 1960년대 초중반까지의 우파를 미들 클래스 가운데 모더니티에 적응하지 못한채 병리적 증상을 보이는 사이비-보수주의 집단으로 규정하였다. 둘째, 1980년대 이후의 연구 경향을 대표하는 에드설 부부와 댄 T. 카터 등의 연구는 백인 노동계급이 보수화된 현상의 기저에는 역차별에 대한 반발감이 놓여 있었다는 사실을 강조하면서 정치인들이 ‘위에서부터 아래로’ 자신들의 정치적 이익을 위해 이러한분노를 활용한 측면에 분석의 초점을 맞추었다. 마지막으로 최근 제시된 우파 연구는 ‘아래로부터의’ 시각으로 우파 구하기를 시도하였다. 예컨대 로널드 P. 포미사노와 리사 맥거는 아래로부터 형성된 우파의 풀뿌리 운동에 주목하고 보수주의활동가들에게 목소리를 부여함으로써 이들의 정치 참여가 1980년대 보수 혁명의원동력이었음을 밝혀냈다 This essay examines the diverse trajectories of historical scholarship that has focused on the ways in which the American Right, once perceived as a marginalized group, succeeded in dominating American politics in the late twentieth century. First, the consensus scholars represented by Richard Hofstadter maintained that the Right of the late 1950s and early 1960s was a pathological pseudo-conservative who had middle-class status but failed to adapt himself/herself to modernity. Second, the Edsalls and Dan T. Carter began to develop the dominant discourse in the 1980s and afterward on the Right. They highlighted that white backlash against the Civil Rights Movement led a number of white working-class people to turn to the Right. In addition, they emphasized that politicians tried to manipulate ‘from above’ the anger of white workers for their own political interests. Finally, recent studies of the Right began to rescue the Right by employing the ‘from below’ perspective. For example, Ronald P. Formisano and Lisa McGirr respectively paid attention to grassroots movements of the Right and gave voice to the voiceless conservative rank-and-file activists. They did this while arguing that the activists’ political participation was an engine for the conservative revolution of the 1980’s. (Sungkyunkwan University / chanhaeng@skku.edu)