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      • SCIESCOPUSKCI등재
      • KCI등재

        Sickle Cell Disease and Other Risk Factors for Pediatric Arterial Ischemic Stroke: A Systematic Review and Meta-Analysis

        Cecilia Putri Tedyanto,Laura Wihanto,Eric Hartono Tedyanto,Anna Marita Gelgel,Ni Made Dwita Pratiwi 대한소아신경학회 2024 대한소아신경학회지 Vol.32 No.1

        Purpose: The incidence and mortality rates of arterial ischemic stroke (AIS) among pediatric patients have been frequently reported. While pediatric stroke can have multiple severe effects, its risk factors have not been methodically examined. This systematic review and meta-analysis were completed to summarize the existing evidence regarding risk factors for AIS in pediatric patients. Methods: To gather relevant articles published in the past 15 years, searches were conducted of PubMed and Scopus. Multivariate odds ratios (ORs) and 95% confidence intervals (CIs) were analyzed using Review Manager 5.4. Results: From the initial screening of 507 articles, five articles comprising a total of 1,423 participants were selected for qualitative analysis. Two of these additionally underwent quantitative analysis. Among the total participants, 1,108 children with AIS (77.9%) had arteriopathy as the underlying disease. Types of arteriopathy included moyamoya disease (24.28%), arterial dissection (23.29%), focal cerebral arteriopathy (16.16%), and vasculitis (14.71%). The meta-analysis revealed that being between 6 and 9 years of age (OR, 2.19; 95% CI, 1.76 to 2.73; P<0.00001) and having sickle cell disease (OR, 3.46; 95% CI, 2.38 to 5.05; P<0.00001) were associated with arteriopathy in pediatric AIS. Conclusion: Arteriopathy is the most common risk factor for AIS in pediatric patients, and in turn, an age of 6 to 9 years and sickle cell disease are risk factors for arteriopathy within this demographic.

      • KCI등재
      • Higher Education Institution's Solid Waste Manasement : Practices, Needs, and Opportunities

        Cecilia A. Geronimo,Audie L. Geronimo ASCONS 2018 INTERNATIONAL JOURNAL OF EMERGING MULTIDISCIPLINAR Vol.2 No.3

        Solid waste management is everybody’s concern. Every individual is a producer of waste that is why in the University all contributors of waste were involved in the study. Production of wastes is one thing, the type of waste produced is another, especially, solid waste and yet the produced waste is managed is another issue. The study used mixed methods through questionnaire and interviews to gather data on status, practices, needs, and opportunities of solid waste management. The findings revealed that the status of solid waste in the University in terms of its types are biodegradable, non-biodegradable and recyclable; with regards to the quantity of waste produced every day, during weekdays an average of 50 bags, where bag has a dimension of 100 square centimeters, Saturdays an average of 20 bags and Sundays about 10 bags. There is a disposal area, where all the waste bags are dumped, with a total area of 200 sq. meters, tools such as shovel, spade, cart, and rake are used and segregation of waste is being enforced; participation in trash to cash program is encouraged to lessen the waste to be disposed and collected by the waste collector or hauler, and allotted budget of approximately six thousand pesos per dump truck load per week. The students and non-teaching personnel agreed on most of the items which described needs and opportunities of solid waste management while the faculty members agreed on practices and strongly agreed on the needs and opportunities on solid waste management in the University. There are needs to be addressed and plans to improve the current practices on solid waste management and optimize the identified opportunities to be recognized as a Clean and Green University.

      • KCI등재

        Environmental Friendly Deproteinization and Saccharification of Industrial Fungal Biomass by Enzymatic Processing

        ( Cecilia Perez-cruz ),( Carlos N. Cano-gonzalez ),( Jose Fuentes ),( Nagamani Balagurusamy ),( Carolina E. Vita ),( Roque A. Hours ),( Cristobal N. Aguilar ),( Sebastian F. Cavalitto ),( Juan C. Cont 한국키틴키토산학회 2018 한국키틴키토산학회지 Vol.23 No.3

        Aspergillus niger biomass, an industrial by-product of citric acid fermentation is an emergent source of glycoderivatives with applications in biofuel, cosmetics, feed, energy, food, medicine, and nanotechnology. In this study, the effect of purified neutral protease for deprotenization of fungal biomass studied at various levels (0, 5, 10, 20 and 40 U/100 mg of biomass) and the saccharification of fungal biomass was evaluated with amylolytic enzymes and chitosanases. The efficiency of deproteinization of fungal biomass was based on the enzyme concentration and contact time. Protease at a concentration of 20 U/100 mg of dry biomass and with a contact time of 8 h achieved 30% final deproteinization. No effect on saccharification of A. niger biomass was observed by treatment with purified amylolytic enzymes. Meanwhile, the endo- and exo-chitosanases treatment yielded 54 g of g reducing sugars (equivalent to amino sugars)/ kg of fungal biomass, which can be employed for tailor-made carbohydrate production.

      • KCI등재

        Evaluation of natural and pregelatinized forms of three tropical starches as excipients in tramadol tablet formulation

        Cecilia O. Alabi,Inderbir Singh,Oluwatoyin A. Odeku 한국약제학회 2018 Journal of Pharmaceutical Investigation Vol.48 No.3

        In the present study, tropical starches from three botanical sources, namely millet starch obtained from the grains of Pennistum glaucum (L) R Br (family Poaceae), sorghum starch from the grains of Sorghum bicolor L. Moench (family Gramineae) and cocoyam starch from the tubers of Colocasia esculenta (L) Schott (family Araceae), have been modified and evaluated as directly compressible excipients in tramadol tablet formulations. The starches were extracted from the relevant plant parts and modified by pregelatinization followed freeze drying and used as excipients in tramadol tablets and the tablet properties compared with those made with the natural forms of the starches. The results indicate that starches from the three botanical sources vary in their properties and pregelatinization led to the modification of the physicochemical and material properties of the starches. The pregelatinized starches exhibited better flowability and compressibility than the natural starches. Tramadol tablets prepared with freeze-dried pregelatinized starches generally exhibited higher crushing strength but lower friability than those prepared with the natural starches. The rankings of the crushing strength and the disintegration and dissolution times was cocoyam > millet > sorghum starches, with tramadol tablets containing freeze-dried pregelatinized starches exhibiting significantly (p < 0.01) higher disintegration and dissolution times than tablets made with the natural forms of starches. The freeze-dried pregelatinized starches were suitable as directly compressible excipients and provided controlled release of tramadol indicating their potential application in formulations where slower drug release is desired.

      • KCI등재

        Bracket bonding to polymethylmethacrylate-based materials for computer-aided design/manufacture of temporary restorations: Influence of mechanical treatment and chemical treatment with universal adhesives

        Cecilia Goracci,Mutlu Özcan,Lorenzo Franchi,Giuseppe Di Bello,Chris Louca,Alessandro Vichi 대한치과교정학회 2019 대한치과교정학회지 Vol.49 No.6

        Objective: To assess shear bond strength and failure mode (Adhesive Remnant Index, ARI) of orthodontic brackets bonded to polymethylmethacrylate (PMMA) blocks for computer-aided design/manufacture (CAD/CAM) fabrication of temporary restorations, following substrate chemical or mechanical treatment. Methods: Two types of PMMA blocks were tested: CAD-Temp® (VITA) and Telio® CAD (Ivoclar-Vivadent). The substrate was roughened with 320-grit sandpaper, simulating a fine-grit diamond bur. Two universal adhesives, Scotchbond Universal Adhesive (SU) and Assure Plus (AP), and a conventional adhesive, Transbond XT Primer (XTP; control), were used in combination with Transbond XT Paste to bond the brackets. Six experimental groups were formed: (1) CADTemp ®/SU; (2) CAD-Temp®/AP; (3) CAD-Temp®/XTP; (4) Telio® CAD/SU; (5) Telio® CAD/AP; (6) Telio® CAD/XTP. Shear bond strength and ARI were assessed. On 1 extra block for each PMMA-based material surfaces were roughened with 180-grit sandpaper, simulating a normal/medium-grit (100 mm) diamond bur, and brackets were bonded. Shear bond strengths and ARI scores were compared with those of groups 3, 6. Results: On CAD-Temp® significantly higher bracket bond strengths than on Telio® CAD were recorded. With XTP significantly lower levels of adhesion were reached than using SU or AP. Roughening with a coarser bur resulted in a significant increase in adhesion. Conclusions: Bracket bonding to CAD/CAM PMMA can be promoted by grinding the substrate with a normal/ medium-grit bur or by coating the intact surface with universal adhesives. With appropriate pretreatments, bracket adhesion to CAD/CAM PMMA temporary restorations can be enhanced to clinically satisfactory levels.

      • 연구논문 : 자원봉사활동을 통한 학습효과 증진

        ( Cecilia Isidro Anido ) 극동대학교 사회복지연구소 2013 글로벌사회복지연구 Vol.3 No.1

        고등교육기관은 전통적으로 새로운 지식을 발견하고 연구하는 학문적인 기능을 수행하는 것으로 알려져 왔다. 그러나, 많은 대학들은 교직원과 학생들로 하여금 양질의 학습 및 연수활동에 참여시키기 위해 지역사회 서비스와 자원봉사 활동의 중요성을 인식하고 있다. 자원봉사는 급격하게 변화하는 고등교육 환경에서 실질적이고 경험적인 학습을 제공하고 있다. 본 논문은 아시아 협력 대학에서 수행한 극동대학교 자원봉사 활동이 중요한 학습경험을 제공하고 있음을 보여주고 있다. 자원봉사 경험을 통해 학생들은 세계가 직면한 문제를 인식하고 이해하게 되었으며 세계적 차원의 관점을 얻은바 있고, 미래의 자원봉사활동에 보다 적극적으로 참여하게 되는 기회를 마련하였다. Higher Education Institutions are traditionally known to carry out the scholarly function of research and the discovery of new knowledge. However, many universities recognize the importance of community service and volunteer work to engage the faculty, staff and students in high quality learning and teaching practices. Volunteerism provides practical, experiential learning in the rapidly changing higher education environment. This paper presents the activities undertaken by Far East University volunteers in coordination with partner universities in Asia that provided meaningful learning experiences. Reflections of volunteers showed that they gained a better understanding and awareness of the problems facing the world, gained a more informed world-view, and became open to new ideas and the desire to participate in future volunteer activities.

      • THE USE OF INTERNATIONAL SHORT-TERM INVESTMENTS BY THE FORTUNE 100

        Cecilia Wagner Ricci People&Global Business Association 1997 Global Business and Finance Review Vol.2 No.2

        The enormous growth in the number of American firms engaged in international business has increased the research on global financial management tremendously, with the notable exception of transcontinental working capital management. This paper is an attempt to address this issue. The focus of the paper is international marketable securities. This article reports the results of a survey of the Fortune 100. The purpose of the survey was to obtain information on the use of international short-term investments by major American firms, as well as to identify some predictors of such investment. Thus, the importance of this paper lies in its practical relevance to finance practitioners in managing the treasury function, and to academics teaching working capital management or international finance.

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