Steel scale-CaO composite catalyst for coke combustion and in-situ NO and SO2 removal

Li Zhang,Jingchong Yan,Zhiping Lei,Xianzhong Cao,Tiejun Chun,Zhanku Li,Hengfu Shui,Shibiao Ren,Zhicai Wang,Ying Kong 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.110 No.-

The performance of the steel scale (SS)-CaO composite on the combustion of coke nuts and in-situ reductionof SO2 and NO emission was investigated. Combustion experiments show that SS-CaO compositeaccelerates coke combustion and reduces SO2 and NO emissions concurrently. X-ray diffraction (XRD),scanning electron microscopy (SEM), and electron spin resonance (ESR) were used to investigate thecatalysis mechanism. Results show that SS and CaO have synergistic effect in in-situ denitration. Theincrease of SS and CaO fraction in the composites improve the denitration and sulfur fixation performance,respectively. The denitration activity is mainly attributed to the Fe2O3 in SS and Ca2Fe2O5 formedduring combustion. The desulfurization is due to the sulfur fixation with CaO. The increasing fraction ofCaO in the composites leads to the agglomeration of ash particles. 2%CaO is confirmed as the optimumaddition for catalytic combustion and emission reduction. This work sheds light on the cheap and effectivecatalysts that are potentially useful for iron ore sintering.

[PA-0075] Genome-Wide Association Study and Haplotype Analysis of Alkaline Tolerance at the Rice Germination Stage

Hongjia Zhang(Hongjia Zhang),Seong-Gyu Jang(Seong-Gyu Jang),Ah-Rim Lee(Ah-Rim Lee),Fang-Yuan Cao(Fang-Yuan Cao),Yuting Zeng(Yuting Zeng),Da-Eun Im(Da-Eun Im),Soon-Wook Kwon(Soon-Wook Kwon) 한국육종학회 2022 한국육종학회 공동학술발표집 Vol.2022 No.-

[PA-0076] Genome-wide Association Study for the Resistance to the Brown Spot in Rice (Oryza sativa L.)

Fang-Yuan Cao(Fang-Yuan Cao),Yuting Zeng(Yuting Zeng),Seong-Gyu Jang(Seong-Gyu Jang),Hongjia Zhang(Hongjia Zhang),Sang-Cheol Kim(Sang-Cheol Kim),Soon-Wook Kwon(Soon-Wook Kwon) 한국육종학회 2022 한국육종학회 공동학술발표집 Vol.2022 No.-

MiRNA320a Inhibitor-Loaded PLGA-PLL-PEG Nanoparticles Contribute to Bone Regeneration in Trauma-Induced Osteonecrosis Model of the Femoral Head

Zhang Ying,Li Chuan,Wei Qiushi,Yuan Qiang,He Wei,Zhang Ning,Dong Yiping,Jing Zhenhao,Zhang Leilei,Wang Haibin,Cao Xiangyang 한국조직공학과 재생의학회 2024 조직공학과 재생의학 Vol.21 No.1

BACKGROUND: This study aimed to explore the effect of a nanomaterial-based miR-320a inhibitor sustained release system in trauma-induced osteonecrosis of the femoral head (TIONFH). METHODS: The miR-320a inhibitor-loaded polyethylene glycol (PEG)- Poly(lactic-co-glycolic acid) (PLGA)- Poly-L-lysine (PLL) nanoparticles were constructed using the double emulsion method. The TIONFH rabbit model was established to observe the effects of miR-320a inhibitor nanoparticles in vivo. Hematoxylin–eosin staining and microcomputed tomography scanning were used for bone morphology analysis. Bone marrow mesenchymal stem cells (BMSCs), derived from TIONFH rabbits, were used for in vitro experiments. Cell viability was determined using the MTT assay. RESULTS: High expression of miR-320a inhibited the osteogenic differentiation capacity of BMSCs in vitro by inhibiting the expression of the osteoblastic differentiation markers ALP and RUNX2. MiR-320a inhibitor-loaded PEG-PLGA-PLL nanoparticles were constructed with a mean loading efficiency of 1.414 ± 0.160%, and a mean encapsulation efficiency of 93.45 ± 1.24%, which released 50% of the loaded miR-320a inhibitor at day 12 and 80% on day 18. Then, inhibitor release entered the plateau. After treatment with the miR-320a inhibitor nanoparticle, the empty lacunae were decreased in the femoral head tissue of TIONFH rabbits, and the osteoblast surface/bone surface (Ob.S/BS), osteoblast number/bone perimeter (Ob.N/B.Pm), bone volume fraction, and bone mineral density increased. Additionally, the expression of osteogenic markers RUNX2 and ALP was significantly elevated in the TIONFH rabbit model. CONCLUSION: The miR-320a inhibitor-loaded PEG-PLGA-PLL nanoparticle sustained drug release system significantly contributed to bone regeneration in the TIONFH rabbit model, which might be a promising strategy for the treatment of TIONFH. BACKGROUND: This study aimed to explore the effect of a nanomaterial-based miR-320a inhibitor sustained release system in trauma-induced osteonecrosis of the femoral head (TIONFH). METHODS: The miR-320a inhibitor-loaded polyethylene glycol (PEG)- Poly(lactic-co-glycolic acid) (PLGA)- Poly-L-lysine (PLL) nanoparticles were constructed using the double emulsion method. The TIONFH rabbit model was established to observe the effects of miR-320a inhibitor nanoparticles in vivo. Hematoxylin–eosin staining and microcomputed tomography scanning were used for bone morphology analysis. Bone marrow mesenchymal stem cells (BMSCs), derived from TIONFH rabbits, were used for in vitro experiments. Cell viability was determined using the MTT assay. RESULTS: High expression of miR-320a inhibited the osteogenic differentiation capacity of BMSCs in vitro by inhibiting the expression of the osteoblastic differentiation markers ALP and RUNX2. MiR-320a inhibitor-loaded PEG-PLGA-PLL nanoparticles were constructed with a mean loading efficiency of 1.414 ± 0.160%, and a mean encapsulation efficiency of 93.45 ± 1.24%, which released 50% of the loaded miR-320a inhibitor at day 12 and 80% on day 18. Then, inhibitor release entered the plateau. After treatment with the miR-320a inhibitor nanoparticle, the empty lacunae were decreased in the femoral head tissue of TIONFH rabbits, and the osteoblast surface/bone surface (Ob.S/BS), osteoblast number/bone perimeter (Ob.N/B.Pm), bone volume fraction, and bone mineral density increased. Additionally, the expression of osteogenic markers RUNX2 and ALP was significantly elevated in the TIONFH rabbit model. CONCLUSION: The miR-320a inhibitor-loaded PEG-PLGA-PLL nanoparticle sustained drug release system significantly contributed to bone regeneration in the TIONFH rabbit model, which might be a promising strategy for the treatment of TIONFH.

Possible Epithelial Ovarian Cancer Association with HPV18 or HPV33 Infection

Zhang, Pei-Pei,Zhou, Lei,Cao, Jia-Shi,Li, Yi-Ping,Zeng, Zhi,Sun, Ni,Shen, Li,Zhu, Hao-Yue,Ruan, Yang,Zha, Wen-Ting,Wang, Xin-Yu,Zhang, Ke-Qiang,Zhang, Ran Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.6

The present study was conducted to investigate the prevalence of HPV infection in epithelial ovarian cancer (EOC) in Hunan province. DNA samples were collected from paraffin embedded ovarian tissue from 322 patients with EOC, 99 with ovarian benign tumors and 199 normal persons. The polymerase chain reaction and direct sequencing were used to identify the HPV types in the samples. The relationship between the infection of human papillomavirus (HPV) and the epithelial ovarian carcinoma (EOC) was investigated combined with clinical data. The prevalence of HPV18 and HPV33 in EOC group and benign group was higher than in the normal group. HPV18 and HPV33 may play a role in the development of both EOC and ovarian benign tumor and may participate in the development of EOC with traditional risk factors, family history and abortion, possibly exerting synergistic effects.

Genetic and Expression Analysis of the SIRT1 Gene in Gastric Cancers

Zhang, Cao,Song, Jae-Hwi,Kang, Young-Whi,Yoon, Jung-Hwan,Nam, Suk-Woo,Lee, Jung-Young,Park, Won-Sang The Korean Gastric Cancer Association 2010 Journal of gastric cancer Vol.10 No.3

Purpose: Silent mating-type information regulation 2 homologue 1 (SIRT1) is a nicotinamide adenine dinucleotide-dependent deacetylase. SIRT1 plays an important role in the regulation of cell death/survival and stress response in mammals. The aim of this study was to investigate whether the SIRT1 gene is involved in the development or progression of gastric cancers. Materials and Methods: SIRT1 and p53 genes in 86 gastric cancers were examined for genetic alterations by PCR-single strand conformation polymorphism sequencing, as well as SIRT1 protein expression in 170 gastric cancers by immunohistochemistry. Results: In the genetic analysis, we found SIRT1 and p53 mutations in two and 12 cases, respectively. Two missense mutations, c.599 C>T (T200I) and c.1258 G>A (E420K), were detected in the SIRT1 gene coding region. The SIRT1 and p53 mutation were found in mutually exclusive gastric cancers. The immunohistochemistry revealed that SIRT1 overexpression was found in 95 (55.9%) of 170 gastric cancers. Altered SIRT1 expression was not statistically associated with clinicopathological parameters, including tumor differentiation, location, lymph node metastasis, or p53 expression. Two cases with an SIRT1 mutation showed increased SIRT1 expression. Conclusions: These results suggest that genetic alterations and overexpression of the SIRT1 gene may contribute to gastric cancer development.

Diversity and geographic variation of endosymbiotic bacteria in natural populations of the pea aphid (Acyrthosiphon pisum) in China

Zhang Li,Cao Ya,Zhang Li-Jun,Wang Meng-Yao,Wang Xiao-Tong,Yang Xing-Zhuo,Duan Ting-Yu,Yuan Ming-Long 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.3

Bacterial symbionts in aphids are known to benefit the insect host and associated with aphid’s ecological adaptation. The pea aphid (Acyrthosiphon pisum), an important legume pest worldwide, carries at least eight endosymbionts, providing a model system to study insect–bacteria interactions. However, species diversity and geographic variations of endosymbionts are unknown in Chinese populations; therefore, we characterized symbiont communities and diversity of 27 pea aphid samples from 13 geographic populations of China. Via amplicon high-throughput sequencing and diagnostic PCR, we found that bacterial communities of Chinese populations were dominated by Proteobacteria and Firmicutes. Among eight known endosymbionts, five (Buchnera, Serratia, Hamiltonella, Regiella, and Rickettsia) were detected by both methods, with a specific geographical distribution. The obligate symbiont, Buchnera, was present in all aphid samples, while the four facultative symbionts showed a significant geographic variation. Each population was randomly infected with distinct endosymbionts, ranging from three to five species. Serratia and Rickettsia showed relatively higher abundance in central regions of China, Regiella was predominant in eastern and western China, whereas Ham iltonella showed an extremely low abundance and was absent in four populations. Samples grouped by altitudes showed a significant diversity difference, whereas there was no significant difference between red and green body colors. Bacterial community structures of the Chinese pea aphid populations were mainly influenced by environmental factors, other than body colors. These data can guide the development of potential biocontrol techniques against this aphid.

Preparation and mechanism of high-performance ammonia sensor based on tungsten oxide and zinc oxide composite at room temperature

Zhang Ling,Zhang Hongyan,Chen Cao,Hu Ziyan,Wang Jun 한국물리학회 2023 Current Applied Physics Vol.45 No.-

Based on ZnO and WO3⋅H2O composite (ZW), a high performance ammonia (NH3) gas sensor was synthesized by hydrothermal method. Compared with WO3⋅H2O, ZW sensor has good selectivity and sensitivity for NH3 gas detection at room temperature, with fast response/recovery time of 2.4 s/1.2 s, low detection limit of 0.76 ppm, excellent endurance to humidity and good stability for a long time. With smaller size in it, ZW provides more active sites to absorb NH3 molecules. More free oxygens on surface of ZW will react with more NH3 molecules, thus to improve the sensitivity of ZW. Furthermore, the heterojunction structure of ZW compound can enhance resistance modulation at the interface between ZnO and WO3⋅H2O, which further improves the sensitivity of WO3⋅H2O for NH3 detection. This study shows the combination of ZnO can significantly improve the performance of NH3 gas sensor based on WO3⋅H2O at RT.

Numerical study of wind profiles over simplified water waves

Cao, Shuyang,Zhang, Enzhen,Sun, Liming,Cao, Jinxin Techno-Press 2015 Wind and Structures, An International Journal (WAS Vol.21 No.3

Vertical profiles of mean and fluctuating wind velocities over water waves were studied, by performing Large-Eddy Simulations (LES) on a fully developed turbulent boundary layer over simplified water waves. The water waves were simplified to two-dimensional, periodic and non-evolving. Different wave steepness defined by $a/{\lambda}$ (a : wave amplitude; ${\lambda}$ : wavelength) and wave age defined by $c/U_b$ (c: phase velocity of the wave; $U_b$ : bulk velocity of the air) were considered, in order to elaborate the characteristics of mean and fluctuating wind profiles. Results shows that, compared to a static wave, a moving wave plays a lesser aerodynamic role as roughness as it moves downstream slower or a little faster than air, and plays more aerodynamic roles when it moves downstream much faster than air or moves in the opposite direction to air. The changes of gradient height, power law index, roughness length and friction velocity with wave age and wave amplitude are presented, which shed light on the wind characteristics over real sea surfaces for wind engineering applications.

Anti‑infammatory and antioxidant activities of acteoside isolated from Acanthus ilicifolius var. xiamenensis

Zhang Yifan,Shen Jinhuang,Ma Xinhua,Yao Mingshuang,Zhang Yonghong,Cao Dairong 한국응용생명화학회 2022 Applied Biological Chemistry (Appl Biol Chem) Vol.65 No.3

Acanthus ilicifolius var. xiamenensis (Acanthaceae), a mangrove found in southeastern China, is an herb with strong antiinflammatory property. Phytochemical study of the mangrove showed that the plant has a high content of phenylethanol glycoside acteoside (AC). In this research, the anti-inflammatory activity of acteoside on dextran sodium sulphate (DSS)-mediated mouse ulcerative colitis model were studied. For DSS- mediated colitis in mice, AC can reduce weight loss and DAI score in UC mice, suppress colon shortening and alleviate colon pathological injury. Moreover, AC treatment notably up-regulates IL-10, down-regulates the levels of IL-1β and TNF-α, and inhibits the protein expression of JAK2/STAT3, NF-κB p65, IKKα/β and IKB of colon. In addition, after AC treatment, the level of MDA and NO in colonic tissue were remarkably decreased, while the levels of GSH, SOD, and Nrf2 and HO-1 protein expression levels were significantly increased. These results indicate that AC can activate the Nrf2 signaling pathway by inhibiting the JAK/STAT, iNOS/eNOS and NF-κB signaling cascades, enhance the intestinal barrier function, and effectively reduce DSS-induced UC in mice.