Damage identification for high-speed railway truss arch bridge using fuzzy clustering analysis

Cao, Bao-Ya,Ding, You-Liang,Zhao, Han-Wei,Song, Yong-Sheng Techno-Press 2016 Structural monitoring and maintenance Vol.3 No.4

This study aims to perform damage identification for Da-Sheng-Guan (DSG) high-speed railway truss arch bridge using fuzzy clustering analysis. Firstly, structural health monitoring (SHM) system is established for the DSG Bridge. Long-term field monitoring strain data in 8 different cases caused by high-speed trains are taken as classification reference for other unknown cases. And finite element model (FEM) of DSG Bridge is established to simulate damage cases of the bridge. Then, effectiveness of one fuzzy clustering analysis method named transitive closure method and FEM results are verified using the monitoring strain data. Three standardization methods at the first step of fuzzy clustering transitive closure method are compared: extreme difference method, maximum method and non-standard method. At last, the fuzzy clustering method is taken to identify damage with different degrees and different locations. The results show that: non-standard method is the best for the data with the same dimension at the first step of fuzzy clustering analysis. Clustering result is the best when 8 carriage and 16 carriage train in the same line are in a category. For DSG Bridge, the damage is identified when the strain mode change caused by damage is more significant than it caused by different carriages. The corresponding critical damage degree called damage threshold varies with damage location and reduces with the increase of damage locations.

Molecular Cloning and Expression of a Novel Protease-resistant GH-36 α-Galactosidase from Rhizopus sp. F78 ACCC 30795

Ya Nan Cao,Ya Ru Wang,Hui Ying Luo,Peng Jun Shi,Kun Meng,Zhi Gang Zhou,Zhi Fang Zhang,Bin Yao 한국미생물 · 생명공학회 2009 Journal of microbiology and biotechnology Vol.19 No.11

Secondary Short-Lasting Unilateral Neuralgiform Headache with Conjunctival Injection and Tearing: A New Case and a Literature Review

Ya Cao,Fei Yang,Zhao Dong,Xusheng Huang,Bingzhen Cao,Shengyuan Yu 대한신경과학회 2018 Journal of Clinical Neurology Vol.14 No.4

Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) is a primary headache syndrome with an unclear pathogenesis. However, there is increasing evidence in the literature for secondary SUNCT being attributable to certain known lesions. We explored the possible neurobiological mechanism underlying SUNCT based on all reported cases of secondary SUNCT for which detailed information is available. Here we report a case of neuromyelitis optica spectrum disorders that had typical symptoms of SUNCT that might have been attributable to involvement of the spinal nucleus of the trigeminal nerve. We also review cases of secondary SUNCT reported in the English-language literature and analyze them for demographic characteristics, clinical features, response to treatment, and imaging findings. The literature review shows that secondary SUNCT can derive from a neoplasm, vascular disease, trauma, infection, inflammation, or congenital malformation. The pons with involvement of the trigeminal root entry zone was the most commonly affected region for inducing secondary SUNCT. In conclusion, the neurobiology of secondary SUNCT includes structures such as the nucleus and the trigeminal nerve with its branches, suggesting that some cases of primary SUNCT have underlying mechanisms that are related to existing focal damage that cannot be visualized.

ABO Blood Group, Epstein-Barr virus Infection and Prognosis of Patients with Non-metastatic Nasopharyngeal Carcinoma

Zhang, Ya-Xiong,Kang, Shi-Yang,Chen, Gang,Fang, Wen-Feng,Wu, Xuan,You, Hua-Jing,He, Da-Cheng,Cao, Ya-Lin,Liang, Wen-Hua,Zhang, Li Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.17

Background: A prior study showed blood type A/AB to be associated with an increased risk of nasopharyngeal carcinoma (NPC) compared to subjects with blood type O. However, the relationship between ABO blood groups and prognosis of NPC patients is still questionable. In addition, whether Epstein-Barr virus (EBV) infection is associated with prognosis of NPC patients with different ABO blood groups is unclear. Materials and Methods: We conducted univariate and multivariable Cox regression analyses based on a consecutive cohort of 1,601 patients to investigate the above issues. Results: There was no significant difference in overall survival (OS) between different ABO blood groups (p=0.629), neither between A vs. non-A blood groups (p=0.895) nor AB vs. non-AB blood group (p=0.309) in univariate analyses and after adjusting for other factors. Interaction tests revealed that high immunoglobulin A against Epstein-Barr virus viral capsid antigen (VcA-IgA) level was associated with a favorable prognosis in male patients with UICC stage II disease who had an A blood type (p=0.008), compared with those with non-A blood type. In addition, male patients with an A blood group with a high blood lymphocyte level showeda tendency towards better survival in UICC stage III (p=0.096). Conclusions: ABO blood group status is not associated with the prognosis of patients with NPC. Additionally, blood group A male NPC patients with high VcA-IgA level or high blood lymphocyte counts might be correlated with a favorable prognosis in UICC stage II or III, respectively.

창의성 마인드셋, 목표지향성, 창의적 자기효능감, 영역 창의성의 구조적 관계

조아평(Ya-ping Cao),최지은(Ji-Eun Choi) 한국영재교육학회 2022 영재와 영재교육 Vol.21 No.1

본 연구 목적은 중국 대학생의 창의성 마인드셋, 목표지향성, 창의적 자기효능감, 영역 창의성 간의 구조적인 관계를 규명하고, 목표지향성과 창의적 자기효능감의 이중매개효과를 알아보는 데 있다. 중국 대학생 805명을 대상으로 하였으며, 영역 창의성은 학문, 과학, 예술 영역을 대상으로 하였다. 주요 연구결과는 다음과 같다. 첫째, 창의성장 마인드셋은 숙달목표지향성, 수행목표지향성, 창의적 자기효능감, 그리고 학문적, 과학적, 예술적 창의성에 직접적인 영향을 미치고, 숙달목표지향성을 매개로 학문, 예술적 창의성에 간접적 영향을, 창의적 자기효능감을 매개로 학문적, 과학적, 예술적 창의성에 간접적인 영향을 미치는 것으로 나타났다. 둘째, 창의고정 마인드셋은 학문, 과학적 창의성에만 직접적인 영향을 미치는 것으로 나타났다. 또한 창의고정 마인드셋은 숙달목표지향성을 매개로 학문적, 과학적, 예술적 창의성에 부적 영향을 미쳤고, 수행목표지향성을 매개로 과학적 창의성에 부적 영향, 예술적 창의성에는 정적으로 간접 효과가 나타났다. 셋째, 창의성 마인드셋과 영역 창의성 간의 관계에서 목표지향성과 창의적 자기효능감의 이중 매개효과는 숙달목표지향성과 자기효능감의 경로에서만 유의하였고, 수행목표지향성과 자기효능감의 경로는 유의하지 않았다. 본 연구를 통해 창의성의 변화신념을 갖는 것이 영역 창의성을 향상시키는 데 유익함을 확인하였다. 마지막으로 본 연구에 대한 의의와 후속 연구를 위한 제언을 하였다. This study examines the relationship between creative mindset and domain-specific creativity and the role of goal orientation and creative self-efficacy in doble-mediating the relation. The research data were collected from 805 Chinese university students. The results found that (1) the growth creative mindset had a direct effect on mastery goal orientation, performance goal orientation, creative self-efficacy, and domains of creativity (Scholarly, Scientific, Artistic), indirect effect on domains of creativity (Scholarly, Artistic) through mastery goal orientation, and an indirect effect on domains of creativity (Scholarly, Scientific, Artistic) through creative self-efficacy. (2) The fixed creative mindset had a direct effect on domains of creativity (Scholarly, Scientific) only. Also, the fixed creative mindset had a negative effect on domains of creativity (Scholarly, Scientific, Artistic) through mastery goal orientation and a negative effect on domain of creativity (Scientific) and positive effect on domain of creativity (Artistic) through performance goal orientation. (3) In the relationship between creativity mindset and domains of creativity, the doble-mediating effect of goal orientation and creative self-efficacy was significant only in the path of mastery goal orientation and self-efficacy, but not in the path of performance goal orientation and self-efficacy. Therefore, the growth creative mindset is beneficial to enhance domains of creativity. The significance of this study and suggestions for future research are discussed.

Sepsis induces variation of intestinal barrier function in different phase through nuclear factor kappa B signaling

Ying-Ya Cao,Zhong-Han Wang,Qian-Cheng Xu,Qun Chen,Zhen Wang,Wei-Hua Lu 대한생리학회-대한약리학회 2021 The Korean Journal of Physiology & Pharmacology Vol.25 No.4

The intestinal barrier function disrupted in sepsis, while little is known about the variation in different phases of sepsis. In this study, mouse models of sepsis were established by caecal ligation and puncture (CLP). The H&E staining of sections and serum diamine oxidase concentration were evaluated at different timepoint af-ter CLP. TUNEL assay and EdU staining were performed to evaluate the apoptosis and proliferation of intestinal epithelium. Relative protein expression was assessed by Western blotting and serum concentrations of pro-inflammatory cytokines was mea-sured by ELISA. The disruption of intestinal barrier worsened in the first 24 h after the onset of sepsis and gradually recovered over the next 24 h. The percentage of apop-totic cell increased in the first 24 h and dropped at 48 h, accompanied with the prolif-erative rate of intestinal epithelium inhibited in the first 6 h and regained in the later period. Furthermore, the activity of nuclear factor kappa B (NF-κB) presented similar trend with the intestinal barrier function, shared positive correction with apoptosis of intestinal epithelium. These findings reveal the conversion process of intestinal barrier function in sepsis and this process is closely correlated with the activity of NF-κB signaling.

The Synthesis and Research of Glass Fiber Felts Coated with Graphene Oxide/Phenolic Resin Binder

Ya Hu,Zhaofeng Chen,Cao Wu,Fei Wang,Sheng Cui,Sufen Ai,Yong Yang 한국섬유공학회 2019 Fibers and polymers Vol.20 No.4

Glass fiber felts (GFFs) coated with reduced graphene oxide (RGO)/phenolic resin (PF) binder was prepared by in-situ reduction reaction, subsequently spraying, and curing process. The effects of the RGO content on the thermal, antiablative, hydrophobic, and mechanical properties of GFFs were studied. Fourier-transform infrared (FT-IR) spectra, X-ray diffraction (XRD) and electronic differential system (EDS) analysis revealed that the graphene oxide (GO) was reduced to RGO by phenol during the in-situ polymerization. Thermogravimetry (TG) and DTG analytical diagram demonstrated that the thermal stability of GFFs was also significantly improved with the addition of GO due to the barrier effect of the lamellar structure. Also, by addition of 0.4 wt% of GO, hydrophobicity was improved by 39 % and the tear strength was improved by 57 % owning to its unique structure and the effective external load transfer. Moreover, the compatibility with PF matrix was improved, endowing good anti-ablative, excellent hydrophobicity and mechanical properties for GFFs.

Effects of chlorantraniliprole and chromafenozide on mortality and feeding cessation of the fall webworm, Hyphantria cunea (Lepidoptera: Arctiidae)

Ya-Jun Gong,Jin-Cui Chen,Shao-Kun Guo,Pan Shi,Li-Jun Cao,Ming-Liang Li,Ary A. Hoffmann,Shu-Jun Wei 한국응용곤충학회 2020 Journal of Asia-Pacific Entomology Vol.23 No.4

The fall webworm (FWW) Hyphantria cunea, native to North America, is a globally invasive pest of a wide range of forest and fruit trees. Spraying of pesticides is the primary method for the control of FWW. In this study, toxicity and feeding cessation of two potential pesticides against the FWW, chlorantraniliprole, and chromafenozide, were evaluated. Both pesticides were slow to affect FWW. For chlorantraniliprole, the highest mortality of third instar larvae occurred at 72 h with an LC 50 of 10.34 mg/L, while for chromafenozide, the highest mortality occurred at 72 h with an LC 50 value 74.0950 mg/L. Low concentrations of both pesticides led to larvae ceasing to feed after six hours (chlorantraniliprole) and 24 h (chromafenozide). Both pesticides had persistent effects; thirty days after being applied at concentrations of 16, 26.67, and 35.56 mg/L to leaves, 93.33% of newly contacted larvae died after seven days. Our study showed that chlorantraniliprole and chromafenozide could be alternatively used against FWW and form a component of integrated control programs. The results provide information to guide the usage of chlorantraniliprole and chromafenozide in FWW control.

Efficacy of First-line Chemotherapy Affects the Second-Line Setting Response in Patients with Advanced Non-Small Cell Lung Cancer

Cao, Wa,Li, Ai-Wu,Ren, Sheng-Xiang,Chen, Xiao-Xia,Li, Wei,Gao, Guang-Hui,He, Ya-Yi,Zhou, Cai-Cun Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.16

Background: Chemotherapy is the mainstay of treatment for the majority of patients with advanced non-small cell lung cancer (NSCLC) without driver mutations and many receive therapies beyond first-line. Second-line chemotherapy has been disappointing both in terms of response rate and survival and we know relatively little about the prognostic factors. Materials and Methods: One thousand and eight patients with advanced NSCLC who received second-line chemotherapy after progression were reviewed in Shanghai Pulmonary Hospital, China, from September 2005 to July 2010. We analyzed the effects of potential prognostic factors on the outcomes of second-line chemotherapy (overall response rate, ORR; progression free survival, PFS; overall survival, OS). Results: The response and progression free survival of first-line chemotherapy affects the ORR, PFS and OS of second-line chemotherapy (ORR: CR/PR 15.4%, SD 10.1%, PD2.3%, p<0.001; PFS: CR/PR 3.80 months, SD 2.77 months, PD 2.03 months, p<0.001; OS: CR/PR 11.60 months, SD 10.33 months, PD 6.57 months, p=0.578, p<0.001, p<0.001, respectively). On multivariate analysis, better response to first-line therapy (CR/PR: HR=0.751, p=0.002; SD: HR=0.781, p=0.021) and progression within 3-6 months (HR=0.626, p<0.001), together with adenocarcinoma (HR=0.815, p=0.017), without liver metastasis (HR=0.541, p=0.001), never-smoker (HR=0.772, p=0.001), and ECOG PS 0-1 (HR=0.745, p=0.021) were predictors for good OS following second-line chemotherapy. Conclusions: Patients who responded to first-line chemotherapy had a better outcome after second-line therapy for advanced NSCLC, and the efficacy of first-line chemotherapy, period of progression, histology, liver metastasis, smoking status and ECOG PS were independent prognostic factors for OS.

Improvement in Water Resistance of Desulfurized Gypsum by Novel Modification of Silicone Oil Paraffin Composite Emulsion-based Waterproofing Agent

Cao, Jing-Yu,Li, Jin-Peng,Jiang, Ya-Mei,Wang, Su-Lei,Ding, Yi,Oh, Won-Chun The Korean Ceramic Society 2019 한국세라믹학회지 Vol.56 No.6

In this study, dimethyl silicone oil and liquid paraffin were combined and subsequently emulsified; the resulting mixture was innovatively incorporated into desulfurized gypsum to resolve its drawback of a poor water resistance. The waterproof mechanism of the composite emulsion and liquid paraffin emulsion with mass fractions of 1%, 2%, 3%, and 4% were investigated. The effect of the desulfurized gypsum on the waterproof performance and basic mechanical properties were also investigated. The configuration of the composite waterproofing agent was characterized by FTIR and ¹HNMR. The results showed that, compared with the traditional liquid paraffin emulsion-based waterproofing agent, the softening coefficient of the silicone oil paraffin composite emulsion-based water-repellent agent was increased by 60% and attained a value of 0.89. Combined with the waterproof mechanism and microscope morphology analysis of gypsum hydration products, the improvement in the water resistance of water resistance was primarily attributed to the formation of a silicone hydrophobic membrane between the crystals of the gypsum block; this ensured that water could not penetrate the crystal.