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최정민,이송주,김부경,최영식,박요한,김정훈,허방 고신대학교 의과대학 2009 고신대학교 의과대학 학술지 Vol.24 No.1
The diffuse sclerosing variant (DSV) is a rare malignant tumour that accounts for 0.7-5.3% of all papillary thyroid cancers. DSV tends to occur at a younger age and has a higher incidence of cervical lymph node metastases, compared with papillary thyroid carcinoma. A 62-year-old female patient diagnosed thyroid nodule with diffuse and mild increased 18F-deoxy-glucose (FDG) on FDG positron emission tomography (PET)-computed tomogram (CT) scan. The ultrasound images showed typical findings of DSV such as diffusely enlarged thyroid lobes and diffusely scattered microcalcification. We performed this patient ultrasonography guided fine needle aspiration and cytologic analysis revealed papillary carcinoma. Total thyroidectomy with central compartment node dissection and lateral lymph node dissection was performed and finally diagnosed DVS. The authors report this case with literature review.
韓國産 紅花子와 中國産 紅花子가 鎭痛 , 消炎 및 關節炎에 미치는 效果
서부일,이은숙,박지하,김상찬,변부형,최호영 대한본초학회 2001 大韓本草學會誌 Vol.16 No.1
This experimental study was done to compare the efficacy of Korean and Chinese Carthami Semen on analgesic effect and remedy of inflammation and arthritis. The results were as follows; 1. In analgesic action on the writhing syndrome in mice induced by 0.7% acetic acid, Korean and Chinese Carthami Semen extract group showed significant decrease in comparison with control group. And in analgesic action on the writhing syndrome in mice induced by Acetylcholine HC1, Korean and chinese Carthami Semen extract group showed significant decrease in comparison with control group. 2. In Anti-inflammatory effects, Chinese Carthami Semen extract group showed significant decrease at 150 and 180 minutes after inducing paw-edema in comparison with control group. 3. In the method of adjuvant arthritis, orally administered for 21 days, Korean Carthami Semen extract group showed significant inhibition of the hind paw edema after 1 day and 21 days. Whereas Chinese Carthami Semen extract group showed some reduction, but the results didn's show significant decrease. 4. In the level of leucocytes count, Korean and Chinese Carthami Semen extract group showed significant decrease in comparison with control group. And in the level of total protein. CRP and glucose, Korean and Chinese Carthami Semen extract group didn't showed significant change in comparison with control group.
권오경,문제기,손부헌,최영희 한국의류산업학회 2003 한국의류산업학회지 Vol.5 No.4
In this study, we measured the antibacterial activities, deodorization, UV cut ability, whiteness and SEM, according to the size(5 μm, 15 ?m) of ThiO₂, concentration(3%, 5%, 10%) and dipping temperature(50℃, 70℃) with using anatase type of TiO₂ photocatalyst. Photocatalyst is the substance which carries out functions, such as decomposition, removal, deodorization, antibacterial, etc. of a contaminant, in a place with light based on an oxidation-reduction reaction. The results of this study were as follow. Antibacterial activities are increased with increasing of the TiO₂'s concentration, and TiO₂ has high antibacterial activities for Staphylococcus aureus but it has low antibacterial activities for Klebsiella pneumoniae. The deodorization and UV cut ability is very good, therefore be able to get good effects with usingonly 3% of TiO₂. Every effects are increased by using small size of TiO₂ and high dipping temperature.
마이크로 콘트롤러를 사용한 극배치 PID 자기동조기의 구성
하재해,추연규,임영도,최부귀 동아대학교 공과대학 부설 한국자원개발연구소 1993 硏究報告 Vol.17 No.2
In this paper, a speed controller using one-chip microcontroller is implemented and applied to a DC Servo Motor. Adaptive control is applied to a system for which a priori knowledge to its mathematical model is insufficient, on the basis of input and output data an apropriate controller is constructed through which the system input is synthesized. The pole-placement PID self tuning control algorithms as a control algorithm is used to research the performance of the controller through experiments.
( Young Eun Kim ),( Hyung Chul Choi ),( In-chul Lee ),( Dong Yeon Yuk ),( Hyosung Lee ),( Bu Young Choi ) 한국응용약물학회 2016 Biomolecules & Therapeutics(구 응용약물학회지) Vol.24 No.6
3-Deoxysappanchalcone (3-DSC) has been reported to possess anti-allergic, antiviral, anti-inflammatory and antioxidant activities. In the present study, we investigated the effects of 3-DSC on the proliferation of human hair follicle dermal papilla cells (HDPCs) and mouse hair growth in vivo. A real-time cell analyzer system, luciferase assay, Western blot and real-time polymerase chain reaction (PCR) were employed to measure the biochemical changes occurring in HDPCs in response to 3-DSC treatment. The effect of 3-DSC on hair growth in C57BL/6 mice was also examined. 3-DSC promoted the proliferation of HDPCs, similar to Tofacitinib, an inhibitor of janus-activated kinase (JAK). 3-DSC promoted phosphorylation of β-catenin and transcriptional activation of the T-cell factor. In addition, 3-DSC potentiated interleukin-6 (IL-6)-induced phosphorylation and subsequent transactivation of signal transducer and activator of transcription-3 (STAT3), thereby increasing the expression of cyclin-dependent kinase-4 (Cdk4), fibroblast growth factor (FGF) and vascular endothelial growth factor (VEGF). On the contrary, 3-DSC attenuated STAT6 mRNA expression and IL4-induced STAT6 phosphorylation in HDPCs. Finally, we observed that topical application of 3-DSC promoted the anagen phase of hair growth in C57BL/6 mice. 3-DSC stimulates hair growth possibly by inducing proliferation of follicular dermal papilla cells via modulation of WNT/β-catenin and STAT signaling.
Determination of Fe in Brown Rice of Heuristic set by using ICP-OES
Bu-Woong Choi,Win Htet Oo,Ji-Hyock Yoo,Min-Young Yoon,Tae-Sung Kim,Won-il Kim,Yong-Jin Park 한국육종학회 2014 한국육종학회 심포지엄 Vol.2014 No.07
Iron is an essential mineral found in every cell of the human body to make the oxygen-carrying proteins hemoglobin and myoglobin. More than 2 billion people face Fe deficiency. Rice can be a potentially valuable source to supplement that mineral since it is staple food for two-thirds of the world’s population. To bring the nutritional level of the milled product up to that of the whole grain (brown), rice should be enriched with thiamin, niacin and iron. Thus we searched a possible allelic source from Heuristic or core rice set, which is derived from a total 24,368 rice germplasms, to increase the mineral content in rice varieties. The concentration and distribution of Fe in 137 accessions of core set of brown rice grain flour sample were determined by ICP-OES. The range of the concentration and distribution of Fe in 137 core accessions of brown rice grain were wide, from 0.088mg/L to 1.205mg/L, with mean 0.292mg/L. To examine Fe related genes, whole-genome resequencing data of 137 accessions of rice core set were analyzed by Genome Wide Associations Study (GWAS). Our result suggests that Fe determined by ICP-OES facilitates the evaluation of the differences in Fe composition for future rice breeding program
콘텐트 연계를 통한 주제기반 커뮤니티 모델 개발 연구 -생명과학 분야를 중심으로-
안부영 ( Bu-young Ahn ),최선희 ( Seon-heui Choi ),신용주 ( Yong-ju Shin ),김순영 ( Soon-young Kim ) 한국정보처리학회 2008 한국정보처리학회 학술대회논문집 Vol.15 No.2
국내외 연구자들은 각자의 분야에서 다양하고 중요한 연구를 수행하면서 그 연구결과물을 생산하고 있다. 연구결과물의 형태는 학회지 및 학술대회 논문, 연구보고서, 특허, 연구노트, 세미나 발표자료, 학교교재, 신문 및 잡지의 기사 등 매우 다양하다. 이런 다양한 연구결과물을 같은 학문 분야, 같은 주제의 연구자들끼리 서로 공유하고 교환하기 위해서는 정보의 자유로운 이용에 근거한 커뮤니티 환경이 필요하다. 이에, 국가 과학기술정보 유통기관인 한국과학기술정보연구원(KISTI)에서 보유하고 있는 문헌 콘텐트와 사실 콘텐트를 주제별로 분류하고 재가공하여 특정 주제분야 전문 연구자들을 위한 오픈 아카이빙, 오픈 액세스 개념을 적용한 커뮤니티 모델을 개발하여 제공하고자 한다. 본 커뮤니티 모델은 요즘들어 가장 많은 연구가 진행되고 있는 생명과학 분야의 연구결과물을 중심으로 개발하였다. 커뮤니티 모델을 개발하기 위하여 1) KISTI가 보유하고 있는 콘텐트 현황을 조사하고, 2) 그 중에서 생명과학분야 콘텐트의 형태와 특성을 분석하고, 3) 연구자들이 연구결과물을 자유롭게 업로드/다운로드할 수 있는 웹 환경의 플랫폼을 설계하였다.