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        흰쥐 안면신경핵 세포의 전기생리학적 및 형태학적 특성

        최병주,조진화,배용철,김영진 大韓小兒齒科學會 2000 大韓小兒齒科學會誌 Vol.27 No.3

        흰쥐의 안면신경핵을 구성하는 신경세포들의 시냅스 연결 양태 및 세포막 특성을 규명하기 위해 in vivo 필드전위 및 세포내 전위 측정법을 이용하여 전기생리적 반응을 관찰하였다. 말초 안면신경 분지를 역행성으로 전기자극시 자극세기에 비례하여 전위의 크기가 증가되었고 필드 전위의 양태는 두 가지 반응으로 나타났는데 전기자극 직후 1ms 부근에서 정점을 나타내는 양태와 이와 더불어 7~8ms 부근에서 후기 정점을 동반하는 양태가 있었다. 안면신경핵은 염색시 내측, 배외측, 중간측 및 외측등 4부분의 소핵으로 구분되었다. Neurobiotin으로 채워진 단일 신경세포를 형태학적으로 재구축하였는데 세포체는 추체형태를 나타내었고 주 수상돌기는 모든 방향으로 뻗어져 있었고 각 수상돌기의 영역은 해당 소핵 내에 한정되어 있었다. 일련의 과분극 전류(-1.2~+1.2nA)를 세포내에 가하였을 때 동반되는 세포내 전위변화를 입력저항 값으로 계산하였을 때 그 기울기가 직선형으로 나타났다. 탈분극 전류를 세포내 주입시 지속적인 활동성 전위가 나타났으며 전류의 크기에 비례하여 각 전위의 개수가 증가하였고 spike-빈도 적응 현상이 나타났다. 그러나 시간 의존성 내향성 정류현상은 관찰되지 않았고 anodal break excitation이 나타났다. 이상의 실험결과로 보아 안면신경핵을 구성하고 있는 세포들 사이의 시냅스는 다양한 형태로 존재할 가능성이 있다고 사료되며 이들 시냅스간의 변화를 통하여 안면 신경마비, 반쪽 안면 경련, hypoglossal-facial anastomosis등에서 나타날 수 있는 임상적 신경성 증상 기전을 설명할 수 있을 것으로 여겨진다. 주요어 : 안면신경핵, 시냅스, 신경세포막 특성, 안면신경마비, 반쪽 안면 경련 This study used in vivo intracellular and extracellular fIeld potential recording to evaluate the intrinsic membrane properties and connection pattern within facial nucleus. 1.There were four subdivisions of medial, intermediate, lateral, and dorsolateral in facial nucleus. 2.Principal cells in the facial nucleus was recorded from and filled with neurobiotin in anesthetized rats. The extent of their dendrites and the characteristics of cell body were examined. 3.Principal cells had a large amplitude action potential and afterhyperpolarization was followed a single action potential. 4.The response from facial motonucleus to electrical stimulation of the facial nerve was mainly a monophasic wave, with a latency of 1 msec, which was assumed to reflect antidromic activation of facial motoneurons. In some of rats the response in addition showed late components at a latency of about 7-8 msec, but its amplitude was small. 5.Mest of cells exhibited accommodation of spike discharge upon depolarization of membrane by 0.8 nA for 400 ms. Our results support the hypothesis that there normally are weak connections between different parts of the facial motonucleus to explain pathophysiology of hemifacial spasm and facial nerve paralysis.

      • 중학교 과학교육 행사에 관한 과학교사의 인식연구(Ⅱ)

        최병철,정호용 여수대학교 2002 論文集 Vol.17 No.-

        The various science fair have the objection and the role in cultivating diverse experiences and dreams for science to students in the scientific education of the middle school. As the results in his study, it is discovered through this investigation there to be estrangements between the contents of programs for various items executed on the spot and the science teacher's recognitions. According to the analysis I will find the previewing points of the solving-methods for revealed problems to make narrow between the poles of estrangements.

      • 실시간 시스템인 승강기 제어기 프로그램 개발

        최병욱,임계영,고경철 제어·자동화·시스템공학회 1999 제어·자동화·시스템공학논문지 Vol.5 No.5

        This paper discusses a real time multi-tasking system model and a development environment for an elevator control system. Recently, as the elevator systems become large-scaled and operate with high speed, there are lots of software tasks to be processed with time constraints. Thus, the control systems are designed with distributed control structure and characteristics of typical real time systems. For structural design of such real time system, we introduce a multi-tasking model based on a real time operating system model and an software development environment based on virtual prototyping which simulates real system operation in the cross development environment. The developed system model and the development environment are successfully applied to development of a new elevator system with distributed control structure and its system reliability can be verified through numerous field tests.

      • 마르크스主義 社會正義論에 關한批判的 硏究

        최일성,홍용희,노병철 忠州大學校 2003 한국교통대학교 논문집 Vol.38 No.1

        This dissertation attempts to examine the theories of social justice in Marxism. The Marxist critique of justice requires us to raise the issue of whether justice has a distinctive meaning beyond conformity to established rules and practices and, if so, if this can be distinguished from and related to other social and political ideals. Marx's contention is that rights and justice are essentially bourgeois ideas which impress the ideology of capitalist economic organization. If justice is indeed an intrinsically capitalist concept, then it is predictable that those who propound a normative theory of justice will express the values of bourgeois individualism. There is a good deal of textual evidence for Marx's theoretical amoralism and his anti-justice and anti-rights stances. Certainly Marx did not think that juridical concepts like justice have any significant role to play in the explanation of social structure and social change. Nevertheless Marx's radically different starting-point implies that a socialist theory of justice must differ from liberal theories not only in the content of its principles but also in the function which it allots to justice discourse. Marx rejected Mill's choice criterion of value and Rawls' conception of deliberative rationality as individualistic abstractions. Especially the concept of exploitation plays a key role in Marx's attack on capitalism. Marx's views on justice and rights rejected the idea that juridical conceptions are the most fundamental conceptions for explaining social phenomena. This rejection of the juridical model is, of course, an inference from Marx's materialist views on the relation between the base and the superstructure of a given society. Marx concludes that juridical conceptions of justice and rights play neither a major explanatory nor a major critical role. Marx is committed to a very radical position on the state and social justice. We argue that this radical evaluative perspective is more epistemological than moral in any traditional sence.

      • KCI등재후보

        유교의 정치이론과 종교교육적 구현

        崔秉喆 韓國宗敎敎育學會 2002 宗敎敎育學硏究 Vol.15 No.-

        유교의 이론은 언제나 도덕과 윤리를 교육철학 내지는 정치원리의 중요한 요소로 간주한다. 한마디로 국가공동체를 경영하는 데는 무엇보다 먼저 자신을 수양하고 남을 다스려야 한다는 ‘수기치인’으로 설명된다. 자신의 수양은 바로 학문과 교육이요, 남을 다스린다함은 공동체의 안녕과 번영을 위한 정치를 의미한다. 그러나 국가체제의 정치와 교육은 ‘하늘’(天)이라는 절대개념과 이론적으로 불과분의 관계이다. 여기서는 유교의 정치·교육적 해석과 종교교육적 의미연관을 탐색하고자 한다. 결론적으로 유교에서 정치적 공동체 이론과 교육적 개별자 이론을 매개하고 절대적 가치로 설정한 것이 하늘의 개념이다. 정치는 하늘의 뜻을 구현하는 일이며 교육의 핵심도 하늘의 뜻과 합일하려는 이론적 근거이다. 정치와 교육이 하늘이라는 절대적·자연적 존재에 의하여 매개되며 그 도덕성에 의하여 종교성이 구현되는 것임을 말해 준다. 가정의 도에는 먼저 어버이부터 모범이 되는 부도(父道)가 있고, 교육에는 사도(師道)가 있으며, 정치적 구현에는 왕도가 있는 바, 군·사·부(君師父) 일체가 성립된다. 이러한 유교의 공동체 이론은 하늘을 절대적 존재로 인식, 정치와 교육적 합일을 이루며 마침내 종교교육적 구현을 이루고자 하는 변증법적 통일성을 지닌다 할 것이다. Confucian political theory has the idea, ‘T'ien Ming’(天命) thought, that all politial decision are derived from Heaven, the absolute being. As a result King is inaugurated by T'ien Ming that are entirely dependent on ‘people's minds’(民心), we have appreciated. Therefore people's minds are stressed first of all in the ‘political road of king’(王道). In the end the ideal community of nation can be formed just when ‘heaven, people and king achieve trinity(天·王·民 三位一體)’. Then we can see a religional pattern in the relations of undivided national units. But the most important unit of nation is people's mind that can't be easily grasped. Only when king plays a role from his mind that loves his people as beings to be loved just as Mencius already proposed that idea, the emperor can be only by people's minds. Mencius compared the political road of king as ideal system to Confucius' desciples more than seventy following him. This is the new proposal of political paradigm that the ideas of road of king is adjusted to the relations of teaching and learning. In this systm people choose their king on their own judges just as the desciples choose their teachers. In the meanwhile there are the principles of members to perform the community of nation, which are one of the ideas of road of king, and the form of nation. The former is described on the above, the latter is the form of nation from T'ien Ming which is called nine categories of wide models(洪範九疇) The religional performance of politic affairs and education in Confucianism includes the theory that our problem can be solved by ‘recovering our good nature’(道德性 恢復). In a sense the fact is proved that there is the performance of the unity between politics and religion through T'ien Ming. In conclusions the absolute value in Confucianism is to realize the concept of T'ien, and politics and education are intermediated by T'ien as the absolute and natural being, and the quality of religion is formed by natural morality. For exemple there is father's way in the family, teacher's way in the education, and the trinity of king, teacher and father for the realization of politics, which represents that there is the dialectic seek of unity in various sides in Confucianism.

      • KCI등재후보

        유아용 승용완구 디자인의 선행조건에 관한 연구

        최병오,신명철 한국기초조형학회 2003 기초조형학연구 Vol.4 No.1

        유아용 승용완구 디자인연구 과정에서 얻어진 구체적인 결론을 요약하면 다음과 같다. 첫째, 안전성-무독성의 재료를 사용하고 날카롭고 뾰족한 부분이 없어야 하며, 유아가 삼킬 수 있을 정도의 작은 크기의 부품이 없어야 한다. 둘째, 세척성-청결을 유지할 수 있도록 세척 가능한 재료를 사용해야 한다. 셋째, 내구성-쉽게 깨어지거나 변형되지 않는 재질을 사용해야 한다. 넷째, 매력적, 흥미성-유아의 호기심을 유발하여 놀이하고 싶은 마음이 들게 하고 놀이를 지속하고 싶은 마음이 들게 해야 하며 모양과 색상이 미적으로 아름다워야 한다. 또한 놀이 방법이 너무 단순하지 않고 다양한 방법으로 활용이 가능해야 한다. 다섯째, 조작성-세발 자전거의 크기와 무게가 유아가 조작하기에 적절하고, 조작방법이 복잡하지 않고 어렵지 않아야 한다. 여섯째, 교육적 기능-여러 가지 감각 경험을 제공하고, 탐색활동을 자극해야 한다. 일곱째, 경제성-가격이 너무 비싸지 않고 다양한 용도로 활용될 수 있어야 한다. This study summarizes the several conclusions in developing tricycle design as follows; First, Safety - The toys for infants should use nontoxic materials, have no sharp parts, and have no parts as small as infants may swallow them. Second, Washing - The toys for infants should use washable materials to maintain cleanliness. Third, Durability - The toys for infants should use the materials that are not easily broken of transformed. Fourth, Attraction & Curiosity - The toys for infants should induce infants to have curiosity for them and thereby make infants want to play with them continuously, and the toy's shape and color should be beautiful. In addition the play method should not be too simple and they should be utilized in various ways.Fifth, Operation - The size and weight of tricycle should be proper for infants to operate, and the operation method should not be too complicated or difficult. Sixth, Educational Function - The toys for infants should provide several senses' experience, simulate search activity and provide the opportunity of problem-solving, and stimulate their imagination and creatively. Seventh, Economical Efficiency - The toys for infants should not be too expensive and can be utilized in various uses.

      • 납중독 흰쥐에서 뇌조직 부위별 Biogenic Amine 함량 변화

        최경규,이병철 梨花女子大學校 醫科大學 醫科學硏究所 1992 EMJ (Ewha medical journal) Vol.15 No.4

        Lead is an neurotoxic substance and its clinical effect on the central nervous system has been well known since several decades ago. As the development of industry becomes more rapid and widespread in the world, we can expect the amount of lead and its harmful effect On the human life would increase in the future. We think the behavioural effect of lead on the central nervous system might be the result of the change of the neurotransmitters in the central nervous system. We studied the change of neurotransmitter amount in the cnetral nervous system of rats after lead intoxication. There was a significant neurotransmitter(catecholamine and 5 hydroxytryptamine) change after lead intoxication in our study.

      • 蓄熱用 TMA 包接化合物의 熱物性에 關한 實驗 硏究(Ⅰ)

        최영범,한영옥,하옥남,김병철,김진흥 조선대학교 동력자원연구소 1996 動力資源硏究所誌 Vol.18 No.2

        This paper presents the test-tube experimental results of thermal properties of TMA clathrate compounds for latent heat storage applications. The results are : ⅰ) subcooling in TMA clathrate compound is the lower than water, ⅱ) Phase change temperature in TMA clathrate compound is the higher than water. ⅲ) Latent heat of 25wt% TMA clathrate compounds of 220.4kJ/㎏K appear to be maximum. ⅳ) Comparing with water, volume of TMA clathrate compounds decreased as the phase change. ⅴ) TMA clathrate compounds precipitated because of increase of density as phase change. Thus, TMA clathrate compounds are found to be the promising compounds for the heat storage from the viewpoint of thermal property.

      • KCI등재

        Small Dam의 斜面安定 解析

        최기봉,배우석,안병철 한국안전학회 2004 한국안전학회지 Vol.19 No.2

        The paper describes a procedure for the evaluation of the effect of seepage force on stability of slopes. The stability of an embankment impounding a water reservoir is highly depend upon the location of seepage line with the embankment. To evaluate the accurate safety factor of an embankment, it is important to illustrate the seepage phenomenon. Of particular interest is the stability following a rapid change of reservoir level. Seepage forces in embankments are easily determined if frictional forces are expressed in relation to hydraulic gradient I. If a piezometer is inserted into a body of embankment, the level to which free water rises is a measure of the energy at that point.

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