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고경식,권선희,김병준,김구엽,서환조 대한감염학회 1995 감염 Vol.27 No.5
목 적 : 최근 칸디다혈증의 발생율이 매우 증가하여 병원 감염의 중요한 원인으로 대두되고 있다. 이에 저자등은 칸디다혈증에 대한 임상적 특성을 알아보기위하여 다음과 같이 연구하였다. 방 법 : 1988년 1월부터 1993년 12월까지 경희대학부속병원에서 발생하였던 병원성 칸디다혈증 61예를 대상으로 의무기록지를 검토하였다. 결 과 : 1) 연도별 발생 빈도는 1988년 부터 1933년까지 각각 2예, 7예, 9예, 11예, 15예, 17예로 증가하였으며, 최근에는 non-albicans 균주에 의한 감염이 증가하고 있었다. 2) 연령분포는 4-83세였으며 평균연령은 51.0±17.4세였고, 남자 32예, 여자 29예였다. 50대와 60대가 57.3%로 가장 많았다. 3) 균주별 발생빈도는 C. albicans 30예, C. tropicalis 13예, C. parapsilosis 10예, C. glabrata 6예, C. guilliermondii 1예, C. krusei 1예로서 C. albicans가 가장 많았다. 4) 기저질환으로 뇌혈관계질환이 25예(41%)로 가장 많았으며, 외과적질환 11예(18%), 고형악성종양 10예(16.4%), 혈액종양질환 9예(14.8%), 기타 내과적질환 6예(9.8%)였다. 5) 균주간 선행인자는 비슷하였으나, C. albicans와 C. tropicalis에서는 수술을 시행받은 예가 많았고, C. parapsilosis는 정주 영양 공급을 받은 경우가 많았다. 6) Amphotericin B 치료군(20예)과 fluconazole 치료군(11예) 사이에 예후에서 유의한 차이는 없었다. 7) 총 61예중 28예에서 사망하여 사망율은 45.9%였으며 정형외과적 수술을 시행받은 경우(83.3%)와 C. glabrata인 경우 사망율이 가장 높았다(83.3%). 결 론 : 칸디다 혈증은 중요한 병원 감염으로 대두되고 있으며 최근에는 non-albicans 진균주에 의한 병원성 칸디다 혈증의 발생율이 증가하는 추세이다. Background : The aim of this study is to determine the annual occurrence of nosocomial candidemia, the relation between Candida species and underlying illness, the relation bewteen Candida species and predisposing factors, and also to compare between the outcome of candidemia of the amphotericin B treatment group and that of the fluconazole treatment group. Methods : We reviewed medical records of 61 cases with nosocomial candidemia between 1988 and 1993 in Kyung Hee University Hospital retrospectively. Results : Two cases occurred in 1988, 7 in 1989, 9 in 1990, 11 in 1991, 15 in 1992, and 17 in 1993. The incidence of candidemia by non-albicans species has increased during this period and accounted for 64.7% in 1993. The infecting candida species were C. albicans(30 cases, 49.2%), C. tropicalis(13 cases, 21.3%), C. parapsilosis(10 cases, 16.4%), C. glabrata(6 cases, 9.8%), C. guilliermondii(1 case, 1.8%), and C. krusei(1 case, 1.8%). The most common underlying disease was cerebrovascular disease(41%) followed by surgical disease(18%), solid cancer(16.4%), hematological malignancies(14.8%), and other medical illness. There were no significant differences between the amphotericin B treatment group(n=20) and the fluconazole treatment group(n=11) in mortality. Overall mortality was 45.9%. The highest mortality was in patients with previous orthopaedic surgery(83.3%) and with C. glabrata candidemia(83.3%). Conclusion : Candidemia emerged as an important hospital infection and candidemia caused by non-albicans species has significantly increased in recent years.
Atypical genital molluscum contagiosum mimicking multiple soft fibromas during pregnancy
( Do-yeop Kim ),( Jungyoon Moon ),( Hyun-sun Park ),( Soyun Cho ),( Byoung Jae Kim ),( Hyun-sun Yoon ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1
Molluscum contagiosum (MC) is a benign disease caused by the molluscum contagiosum virus (MCV), a poxvirus. Usually, it can be diagnosed easily through the observation of characteristic lesions; however, the diagnosis of MC can be difficult if the lesions are atypical, particularly in an immunocompetent adult. A 32-year- old woman presented at 33 weeks of gestation with a 3-month history of multiple asymptomatic, various-sized pedunculated flesh-colored papules in the perianal area without umbilication. She denied having any immunosuppressive disease or chronic infection other than a hepatitis B virus infection. Clinically, soft fibroma was suspected, but punch biopsy revealed the presence of molluscum bodies. MC in the genital area might be accompanied by other venereal infections and may even vertically transmit to neonates. Thus, thorough differential diagnosis, including that for MC, should be performed when new-onset skin lesions develop near the birth canal during pregnancy.
대칭 및 비대칭 2차원 쐐기의 입수 충격에 관한 실험적 연구
김경환(Kyong-Hwan Kim),이동엽(Dong Yeop Lee),홍사영(Sa Young Hong),김영식(Young-Shik Kim),김병완(Byoung Wan Kim) 한국해양공학회 2014 韓國海洋工學會誌 Vol.28 No.3
In the present study, the water impact loads on two-dimensional symmetric and asymmetric wedges were studied. The impact pressure and force were measured during a vertical drop of the symmetric and asymmetric wedges. The measured pressure was compared with analytic solutions. The measured force at a local area of the wedge was compared with the integrated pressures and analytic solutions. Some findings on symmetric and asymmetrical wedge drops are presented, and the reliability of the force sensor used for the measurement of the local impact force is discussed.
Solubilization and polymer analogous reactions of polyepichlorohydrin in ionic liquids
Kim, Byoung Gak,Sohn, Eun-Ho,Chung, Jae-Seung,Kwak, Seung-Yeop,Lee, Jong-Chan Wiley Subscription Services, Inc., A Wiley Company 2009 Journal of applied polymer science Vol.114 No.1
<P>Polyepichlorohydrin containing reactive chloromethyl side groups was found to be highly soluble in polar ionic liquids containing halide anions such as 1-n-butyl-3-methyl imidazolium chloride, 1-n-ethyl-3-methyl imidazolium bromide, and 1-n-hexyl-3-methyl imidazolium chloride, whereas it was insoluble in less polar ionic liquids such as 1-n-butyl-3-methyl imidazolium tetrafluoroborate and 1-n-butyl-3-methyl imidazolium hexafluorophosphate. The reaction of polyepichlorohydrin with thiolates and thiol compounds in the polar ionic liquids as reaction media produced polyoxyethylenes with thioether side groups in very high conversions and yields. When polyepichlorohydrin was reacted with sodium 1H,1H,2H,2H-perfluorinated decanethiolate in 1-n-hexyl-3-methyl imidazolium chloride at 70°C and the product was separated through centrifugation, the ionic liquid could be used more than four times, and high conversions (>70 mol %) and yields (>62 wt %) were maintained. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2009</P>
QS 9000 품질경영 시스템의 도입 및 적용에 관한 연구
이병찬,김준엽 한국품질경영학회 2000 품질혁신 Vol.1 No.1
This study is to increase the competition power by effective application of QS 9000 system in automobile parts companies. To find out managerial suggestion, the main focus was to prove critical factors to implement QS 9000 quality system. The survey was conducted to investigate problems in introducing, processing and implementing QS system. The promoting motives of QS 9000 quality system had good effects to the degree and result of adopting the system. Each factor of promotion motives of QS 9000 has very close relation with the performance. Especially, in the point of satisfying customer's demands, QS 9000 has to be implemented. It is an urgent problem for Korean automobile parts companies to perform common demands in QS 9000. And the special demands which are needed privately bi BIG 3 companies also have to be satisfied. Establishing the quality system which can satisfy customer's needs will bring more successful results. And automobile parts companies should develop the best strategy to constitute quality system for satisfying customer's demands. Besides, the companies which are to adopt QS 9000 will get effective results if they introduce ERP system at the same time.