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鄭敬壽,柳柄泰,金炳珏 충남대학교 약학대학 의약품개발연구소 1985 藥學論文集 Vol.1 No.-
The ether, methanol, and physiological saline extracts of the dried carpophores of ten basidiomycetous fungi, which were collected in the conifer woods of Chungnam National University at Taechon, were subjected to an antibiotic activity test by disc-plate method. Among them, the methanol extracts of Marasmius maximus, Hirschioporus abietinus, and Russula sanguinea and the the ether extracts of M. maximus and H. abietinus showed antibiotic activities against Sarcina lutea; and the methanol and ethanol extract of M. maximus showed antibiotic activity against Staphylococcus aureus. None of the extracts, however, showed any activity against gram negative bacteria, Serratia marcescens and Proteus vulgaris.
鄭敬壽,申明哲,柳柄泰,金炳珏 충남대학교 약학대학 의약품개발연구소 1986 藥學論文集 Vol.2 No.-
The ether, methanol, and physiological saline extracts of the dried carpophores of ten basidiomycetous fungi, which were collected in the conifer woods of Chungnam National University at Taechon and Keyryoung Mountain Area in Chungcheungnamdo, were subjected to an antibiotic activity test by disc-plate method. Among them, the methanol extracts of Inocybe trechispora, Lactarius velumis, and Laccaria laccata and the ether extracts of I.trechispora showed antibiotic activities against Sarcina lutea; and the methanol extracts of I. trechispora and L. velumis and physiological saline extract of Coriolus versicolor showed antibiotic activities against Staphylococcus aureus; and the methanol extract of L. velumis showed antibiotic activity against Escherichia coli. None of the extracts, however, showed any activity against Serratia marcescens and Proteusvulgaris.
韓國産 擔子菌類의 抗菌成分에 관한 硏究 (III) : 10種의 擔子菌에 대한 抗菌成分 檢索
鄭敬壽,白貞花,柳柄泰,金炳珏 충남대학교 약학대학 의약품개발연구소 1987 藥學論文集 Vol.3 No.-
The ether, methanol, and physiological saline extracts of the dried carpophores of ten basidiomycetes, which were collected from several locations of Korea, were subjected to a screening test for antibiotic activity by disc-plate method using Sarcina lutea, Bacillus subtilis, Escherichia coli, and Serratia marcescens as target organisms. As the result, the methanol extract of five basidiomycetes-Amanita rebescens, Amanita solitaria, Lactarius vellereus, Latarius subzonarius and Scleroderma verrucosum-were found te have antibiotic activity. Among them, the methanol extracts of A. rubescens and L. vellereus exerted strong activity against both of the gram positive and negative bacteria. The ether extracts of A. rubescens and S. verrucosum also showed activity against S. lutea. The physiological saline extract, however, showed no activity at all.
건강보험료 체납자에 대한 급여제한 사전통지제도의 효과성 분석
조병희 ( Byong Hee Cho ),유태균 ( Tae Kyun Yoo ),윤성원 ( Seong Won Yun ) 한국사회복지연구회 2013 사회복지연구 Vol.44 No.3
본 연구의 목적은 급여제한 사전통지제도가 건강보험료 체납자의 체납보험료 자진납부에 미치는 영향을 실증적으로 파악하는 것이다. 본 연구에서는 건강보험공단의 전산자료부터2010년 1월 21일에 실시된 제 8차 급여제한 사전통지 대상자 155만 명에 관한 자료를 표본으로 추출한 다음 표본을 체납자집단(사전통지 도달, 사전통지 미도달)과 비체납자집단(비대상 체납자, 차상위)로 분류하고 각 집단으로부터 체납자 규모의 10%에 해당하는 15만 명씩을 최종표본으로 추출하여 분석자료로 사용하였다. 다양한 로지스틱회귀분석모형을 추정한 결과, 급여제한 사전통지제도가 통계적으로 유의한 수준인 체납보험료 납부독려 효과를 가진 것으로 나타났다. 그러나 분석결과의 통계적 유의성과는 별개로 급여제한 사전통지제도의 효과는 매우 제한적인 것으로 나타났다. 연구대상 체납자 중 급여제한 사전통지를 받은 이후 체납보험료의 일부 또는 전부를 납부한 체납자는 직역 차이를 고려하더라도 25% 미만 수준에 불과한 것으로 밝혀졌다. 이처럼 체납보험료 납부율이 저조한 이유는 보험료 체납자 중 상당수가 빈곤으로 인해 보험료 납부능력이 없는 생계형체납자이기 때문이라 판단된다. 이러한 현실을 고려할 때, 건강보험공단이 실시하고 있는 급여제한 사전통지제도나 자진납부기간 운영 등은 일부 체납자에게는 보험료 납부독려 효과가 있으나 대다수의 보험료 체납자들에게는 효과가 없으며 오히려 보험료 체납자의 비용부담을 가중시켜 체납 상황에서 벗어나기 어렵게 만드는 결과를 가져올 수 있다. 본 연구에서는 이러한 연구결과를 바탕으로 급여제한 사전통지제도의 개선을 위한 일련의 정책방안을 제시하였다. One of the challenging tasks of the National Health Insurance Corporation(NHIC). the only public insurance institution administrating the Korea’s compulsory national health insurance(NHI) system, is to make those NHI beneficiaries who fail to make a scheduled monthly premium payment to pay. For this purpose, the NHIC has been using a measure known as ‘Benefit Limit Measure(BLM)’ in which those who miss premium payment for six or more month’s in total are classified as ‘late payer’ and are sent warnings and late payer status notices. If the late payers fail to make a full payment of missed premiums even after receiving the written notices, the NHIC can order a temporary seizure of the late payer’s property until all missed premiums plus interest are paid. Recently, the BLM has been criticized by the public of its cruel nature, and its effectiveness has been questioned because no empirical evidence has been collected. In this study, the authors using the NHIC data set attempted to analyze the effectiveness of the BLM. Those late payers for whom the BLM was administered were compared to those not in terms of the likelihood of paying missed premium payments with a series of logistic regression analyses models. Data analyses results showed that the likelihood of paying one or more month’s unpaid premium of the former group was 14 to 46 times higher than the latter. It, however, was also found that the BLM was only effective to make no more than 12% of the late payers to pay at all. Based on the study findings, the authors made a few recommendations regarding the BLM.
Jae Ho Yoo,Wan Song,Tae Heon Kim,Chan Kyo Kim,Byung Kwan Park,Byong Chang Jeong,Seong Il Seo,Seong Soo Jeon,Hyun Moo Lee,Han Yong Choi,Hwang Gyun Jeon 대한비뇨기종양학회 2017 대한비뇨기종양학회지 Vol.15 No.2
Purpose: To determine the negative predictive value (NPV) of multiparametric magnetic resonance imaging (mp-MRI) for clinically significant cancer (CSC) based on the Prostate Imaging-Reporting and Data System (PI-RADS) version 2 in very low-risk or low-risk prostate cancer patients. Materials and Methods: We retrospectively analyzed 380 patients with low risk of prostate cancer who underwent mp-MRI before radical prostatectomy (RP) from 2011 to 2013. Of the 380 patients, 142 patients were in the very low risk group. CSC at RP was defined as follows: any T3–4, G3+4 with tumor volume>15%, G4+3 or higher. In the very low risk and low risk groups, we analyzed the rate of CSC according to PI-RADS score and calculated the NPV of mp-MRI for detection of CSC. Results: In the low risk group, 20.8% (n=79) of patients had PI-RADS version 2 score 1–2 and 17.4% (n=66) of patients had PI-RADS version 2 score 3. In the very low risk group, 26.8% (n=38) of patients had PI-RADS version 2 score 1–2 and 17.6% (n=25) of patients had PI-RADS version 2 score 3 in the very low risk group. Rates of CSC were 33.7% (n=128) and 16.9% (n=24) in the low risk and very low risk groups, respectively. The NPV of MRI was 93.7% in the very low risk group and 78.6% in the low risk group. Conclusions: The NPV of PI-RADS for CSC is high in the very low risk group, but not in the low risk group. Further multicenter studies are needed to investigate the utility of PI-RADS version 2 for NPV.
왕겨재를 混入한 콘크리트의 工學的 特性에 關한 實驗的 硏究
성찬용,유병인,김경태,정현정,김영익 충남대학교 농업과학연구소 1997 농업과학연구 Vol.24 No.2
This study was performed to evaluate the engineering properties of rice-husk ash concrete using normal portland cement, natural aggregates and rice-husk ash. The following conclusions were drawn; 1. The unit weight was in the range of 2,216~2,325 kgf/㎥, the weights of those concrete were decreased 1~6% than that of the normal cement concrete, respectively. 2. The highest strength was achieved by 10% rice-husk ash filled rice-husk ash concrete, it was increased 8% by compressive strength, 17% by tensile strength and 18% by bending strength than that of the normal cement concrete, respectively. 3. The ultrasonic pulse velocity was in the range of 3,252~4,016 m/s, which was showed about the same compared to that of the normal cement concrete. The highest ultrasonic pulse velocity was showed by 10% rice-husk ash filled rice-husk ash concrete. 4. The dynamic modulus of elasticity was in the range of 242×10^3~306×10^3 kgf/㎠, which was showed about the same compared to that of the normal cement concrete. The highest dynamic modulus was showed by 10% rice-husk ash filled rice-husk ash concrete. 5. The static modulus of elasticity was in the range of 185×10^3~275×10^3kgf/㎠, which was showed about the same compared to that of the normal cement concrete. The poisson's number of rice-husk ash concrete was less than that of the normal cement concrete. The dynamic modulus was increased approximately 11~30% than that of the static modulus. 6. The durability was increased with increase of the content of rice-husk ash. The durability was increased 1.3 times by 10% rice-husk ash, 1.6times by 20% rice-husk ash filled concrete than that of the normal cement concrete, respectively.