좌측흉수로 발현된 Boerhaave 증후군 1예

이준,변유미,조민근,조주연,원경준,김영대,박찬국,김만우,유재근,서홍주,이석기 朝鮮大學校 附設 醫學硏究所 2008 The Medical Journal of Chosun University Vol.33 No.2

구토 후 발생한 토혈을 주소로 내원한 환자에서 좌측 늑막 삼출 동반 시 식도 파열의 가능성을 고려하여 흉수 천자 및 지속적인 흉부 단순 촬영의 추적관찰이 필요하며 식도 파열이 배제된 후 환자의 생체 징후 및 토혈 양을 파악하여 내시경 검사 시기를 신중히 결정하는 것이 좋을 것으로 생각된다. 본 증례는 토혈을 주소로 내원하여 Mallory-Weiss 증후군 의심 하에 내시경을 통한 치료 시행 후 추적 관찰에 의해 진단된 Boerhaave 증후군을 경험하였기에 보고하는 바이다. Boerhaave's syndrome is a spontaneous perforation of the esophagus most commonly resulting from a sudden increase in intraesophageal pressure combined with negative intrathoracic pressure caused by straining or vomiting. Surgery should generally be performed within 24 hours because mortality approached 30 to 50 percent in which surgery was delayed. Therefore, early diagnosis and prompt surgical repair are critical for survival. We have experienced a case of Boerhaave's syndrome in a patient presenting with hematemesis with left pleural effusion without any signs or symptoms of pneumomediastinum or pneumothorax.

제 1형 신경섬유종증 환자에서 발생한 위장관 간질종양 1예

원경준,이준,변유미,조민근,한경택,김원,홍란,임성철,김경종,김영대,박찬국,김만우 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2

Gastrointestinal stromal tumor (GIST) is the most common non-epithelial neoplasm arising in the gastrointestinal tract, but this tumor is rarely seen in association with type l neurofibromatosis (NFl) Generally, the majority of GISTs are isolated neoplasm and they are sporadically found in the stomach, but the GISTs in NFl patients are usually multiple and usually found in the small intestine. We report a case of multiple GISTs in the jejunum of a 63-year-old woman diagnosed as NFl accompanied by complication of gastrointestinal bleeding, In this case, Patient had multiple cafe-au lait spots and neurofibroma on skin and had freckling on axilla and groin, and then, we made a diagnosis of NFl. Gastrointestinal bleeding is controlled by resection of multiple GISTs. Generally, only 3-5% of all gastrointestinal bleeding comes from the small bowel. Causes of small intestinal bleeding are angiodysplasia, neoplasm, NSAIDs induced ulcer etc. but, If patients have NFl accompanied by complication of gastrointestinal bleeding, GISTs on small bowel must be considered.

간경변 환자에서 Oro-cecal Transit Time의 측정

원경준,이준,변유미,조민근,조주연,서정균,김영대,박찬국,김만우 朝鮮大學校 附設 醫學硏究所 2008 The Medical Journal of Chosun University Vol.33 No.2

Background: Neurotransmitter like substances in the gut have been proposed to contribute to the overall portal systemic encephalopathy (PSE). The source of the ammonia in patients with PSE is mainly the small bowel, as a result of the conversion of glutamine in the diet to glutamate and ammonia. PSE is highly responsive to changes in diet, to antibiotic therapy and to ingestion of nondigestible disaccharides such as lactulose. This study was performed to evaluate the relationship between PSE and oro-cecal transit time. In addition, performed to evaluate the effect of severity, cause, complications of liver cirrhosis on oro-cecal transit time. Methods: Between August 2006 and February 2007, 48 cirrhotic patients consecutively was enrolled in study their oro-cecal transit time after informed consent was obtained. A non-invasive hydrogen breath test was used to study oro-cecal transit time (OCTT). Result: The OCTT were delayed in cirrhotic patients with PSE compared without PSE (123.3 ± 42.7 min vs 170.0 ± 58.3 min, p<0.05). OCTT tended to prolongate further as the damage in the liver got worse, nevertheless the result was statistically meaningless (p<0.111). Neither presence of ascites or cause of PSE had any influence on gastrointestinal transit. Conclusions: Cirrhotic patients with PSE have more delayed OCTT than without PSE. Further research is needed to find out the relationship between OCTT and severity of liver cirrhosis.

아메바성 대장염과 연관된 Henoch-Scho¨nlein Purpura 1예

장재현,원경준,이준,변유미,이재광,김영훈,박찬국,김만우 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3

Henoch-SchonIein purpura is a common form of vasculitis primarily involving the skin, the gastrointestinal tract, the joints, the kidneys, and the nervous system. The etiological investigations are essential, because triggering factors are found in approximately half the patients such as viral, bacterial and parasitic infections, drugs, toxins, systemic diseases and cancer. But it's the correlation between Henoch-SchonIein purpura and Entamoeba histolytica has been rarely reported. We report a 29-years-old woman with Henoch-SchoIein purpura complicated by the lower gastrointestinal bleeding caused by the amoebic colitis. She complained of cramping abdominal pain, lower extremity purpura and hematochezia. Cysts and trophozoites of Entamoeba histolytica were detected in her stool. Skin biopsy demonstrated the leukocytoclastic vasculitis. She was administered metronidazole 1,500㎎ a day for the treatment of amebic colitis. Her hematochezia was improved, but the abdominal pain and purpura were not. The subsequent corticosteroid therapy improved her symptoms.

멸종위기종 서식처에 조성된 생태적 수질정화 비오톱 시스템의 수질정화 및 생태복원 효과 -금개구리 서식처인 안터 저수지 생태공원 사례를 중심으로-

변찬우 ( Chan Woo Byeon ) 한국환경복원기술학회(구 한국환경복원녹화기술학회) 2010 한국환경복원기술학회지 Vol.13 No.6

A Sustainable Structured wetland Biotop (SSB) system was planned, designed, and finally constructed, and maintained in the An-teo Reservoir ecological park, which is the habitat of the endangered Gold-spotted Pond Frog. The system purifies polluted water of An-teo Reservoir which flows from up to bottom within the system. Water was sampled once a month at the inlet and at the outlet from December, 2009 to August, 2010. BOD5, SS, T-N and T-P were analyzed. Average influent and effluent BOD5 concentration was 2.9 and 1.0 mg/L, respectively, and BOD5 removal was 67%. SS concentration of influent and effluent averaged 18.1 mg/L and 2.5 mg/L, respectively, and SS abatement amounted to 86%. Average influent and effluent T-N concentration was 0.426 mg/L and 0.147 mg/L, respectively, and T-N retention was 66%. T-P concentration of influent and effluent averaged 0.071 mg/L and 0.022 mg/L, respectively, and T-P removal amounted to 68%. Plant and frog species of the system were monitored during the period. Amphibia and reptiles provided 7 species and 4 families including the Endangered Gold-Spotted Pond Frog (Rana chosenica) which also lives in the system. Twenty-six plant species were naturally introduced into the system, however, they didn`t make up a significant portion of the plant populations compared with the planted species. The endangered plants, Bladderwort (Utricularia vulgaris var. japonica) and Euryale ferox were observed in An-teo Reservoir as well as in the system.

분산형 저류지 생태환경복원 설계 -신정3지구 생태환경저류지에 적용된 생태적수질정화비오톱(SSB) 시스템을 중심으로-

변찬우 ( Chan Woo Byeon ) 한국환경복원기술학회 2013 한국환경복원기술학회지 Vol.16 No.1

The design process of ecological and environmental detention system located in the housing district of Sinjeong 3-jigu in Seoul are as follows. At stage one, a new dispersal detention was created in the neighborhood park located near the originally planned detention. From this, the amount of storage of this dispersal detention system was enlarged from 28,337m1/d. the initial storage amount, to 33,606m3/d as the post storage amount, responsible to the amount of rainfall which happens every 100 years. in particular, the SSB (Sustainable Structured wetland Biotop) system, which was the New Excellent Technology verified by the Ministry of Environment (No. 258) was applied to enhance ecological functioning and water quality with the detention as a constructed wetland. At stage two, the treatment plans for non-point pollutant source occurred at the initial period of rain, flowing into the detention System were built for purifying the water of the retention pond at the base of the detentions, and the water-circulation system was designed at the dispersal detentions on the period of regular rainfalls. The non-point pollutant source flowing into detention site was calculated as 11,699m3/d flowing down from seven small watersheds, which occurred at the initial period of rain. In particular the SSB systems improved the average efficiency of the water processing performance to BOD 60%, SS 90%, T-N 30%, T-P 60%. At stage three, the ecological network and biological diversity were strongly considered so that it brought the residents with amenity places. In particular, the dispersal detentions were successfully designed to restore the ecological habitat of endangered plant and animal species such as narrow-mouthed.

하수처리수의 재이용을 위한 처리습지 및 도시 상류하천 생태환경복원

변찬우 ( Chan Woo Byeon ) 한국환경복원기술학회 2014 한국환경복원기술학회지 Vol.17 No.5

The ecosystem of Jaemin stream, flowing into the center of Gongju-si, had been damaged by low water quality and lack of water quantity of the steam. However, after applying the SSB (Sustainable Structured wetland Biotop) system to the flood plain and the upstream of Jaemin stream, the efficiency of ecological water purification and ecological restoration are as follows. Through the constant maintenance and monitoring from year 2009 to year 2013 after restorative design and construction the average influent concentration of BOD5 was 4.2 mg/L, and the average effluent concentration was 1.8 mg/L, reaching ecological water purification rate of 57%. As for the T-N, the average influent concentration was 9.983 mg/L, and the average effluent concentration was 6.303 mg/L, showing the rate of 37%. For the T-P, the average influent concentration was 0.198 mg/L, and the average effluent concentration was 0.098 mg/L, being the rate of 51%. The vegetation of Jaemin stream monitored for 2 years after the restoration was composed of 51 species in 28 families which show high ratio of planted native species. As for the animals in the site, 5 species in 3 families of reptiles and amphibians, 34 species of 23 families of birds, and 3 species in 2 families of mammals were monitored, indicating that the bio-diversity of the site has improved, as well.

경안천 고수부지에 조성한 금어천 생태적수질정화비오톱 시스템의 수질정화 및 생태복원 효과

변찬우 ( Chan Woo Byeon ) 한국환경보건기술학회(구 한국환경복원녹화기술학회) 2010 한국환경복원기술학회지 Vol.13 No.3

A Sustainable Structured wetland Biotop (SSB) system was constructed on the floodplain of Kyungan stream in December, 2006. It purifies polluted water of Keumeo stream which flows into the stream. Water were sampled once a month at inlet and outlet from December, 2007 to December, 2008. BOD5, SS, T-N and T-P were analyzed. Plant and fish species of the system were monitored twice during the period. Average influent and effluent BOD5 concentration was 6.2 and 2.2 mg/L, respectively and BOD5 removal was 50.8%. SS concentration of influent and effluent was averaged 10.1mg/L and 1.5mg/L, respectively and SS abatement amounted to 77.0%. Average influent and effluent T-N concentration was 4.9mg/L and 2.9 mg/L, respectively and T-N retention was 50.8%. T-P concentration of influent and effluent was averaged 0.386mg/L and 0.107mg/L, respectively and T-P removal amounted to 77.0%. Twenty two plant species were naturally introduced into the system, however, they didn`t make up a significant portion of the plant populations compared with the planted species. Dominant plant species were in the following order; Phragmites communis > Typha latifolia > Iris pseudoacorus > Persicaria thunbergii. Five families and 15 species of fish were observed in the system including Chinese minnow (Moroco oxycephalus) which inhabits in clean water. Six more fish species were monitored in the system compared with ones living in Kyungan stream. Amphibia and reptiles accounted for 11 species of 4 orders and 7 families including Korean Salamander (Hynobius leechi) which also lives in clean water.

A 60-GHz LTCC SiP with Low-Power CMOS OOK Modulator and Demodulator

Byeon, Chul-Woo,Lee, Jae-Jin,Kim, Hong-Yi,Song, In-Sang,Cho, Seong-Jun,Eun, Ki-Chan,Lee, Chae-Jun,Park, Chul-Soon The Institute of Electronics and Information Engin 2011 Journal of semiconductor technology and science Vol.11 No.4

In this paper, a 60 GHz LTCC SiP with low-power CMOS OOK modulator and demodulator is presented. The 60 GHz modulator is designed in a 90-nm CMOS process. The modulator uses a current reuse technique and only consumes 14.4-mW of DC power in the on-state. The measured data rate is up to 2 Gb/s. The 60 GHz OOK demodulator is designed in a 130nm CMOS process. The demodulator consists of a gain boosting detector and a baseband amplifier, and it recovers up to 5 Gb/s while consuming low DC power of 14.7 mW. The fabricated 60 GHz modulator and demodulator are fully integrated in an LTCC SiP with 1 by 2 patch antenna. With the LTCC SiP, 648 Mb/s wireless video transmission was successfully demonstrated at wireless distance of 20-cm.

Cefepime-induced neurotoxicity after flap surgery: a rare case report

Woo Jin Song,Chan Yeong Lee,류형래,Je Yeon Byeon,Hwan Jun Choi 대한수부외과학회 2023 대한수부외과학회지 Vol.28 No.1

Cefepime is a fourth-generation cephalosporin that covers gram-positive bacteria and gram-negative bacteria, such as Pseudomonas. A 48-year-old male patient underwent a posterior tibial artery perforator-based fasciocutaneous turnover flap and was administered cefepime. After 2 days, the patient showed neurological symptoms, such as cognitive decline and aphasia. We immediately stopped cefepime and changed to ciprofloxacin. In addition, thiamine was administered and additional dialysis was performed. The neurological symptoms were resolved after tapering cefepime and hemodialysis. In patients undergoing flap surgery, especially those with impaired renal function, cefepime should be administered carefully considering the risk of neurotoxicity.