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Analysis of Patients with Hemoptysis in a Tertiary Referral Hospital
( Bo Ram Lee ),( Jin Yeong Yu ),( Hee Jung Ban ),( In Jae Oh ),( Kyu Sik Kim ),( Yong Soo Kwon ),( Yu Il Kim ),( Young Chul Kim ),( Sung Chul Lim ) 대한결핵 및 호흡기학회 2012 Tuberculosis and Respiratory Diseases Vol.73 No.2
Background: This study attempted to investigate the main causes of hemoptysis, the type of examinations used for diagnosis, the treatment modalities and outcomes. Methods: A retrospective study was conducted on the medical records of 221 patients admitted to the Chonnam National University Hospital, between January 2005 and February 2010, with hemoptysis. Results: Bronchiectasis (32.6%), active pulmonary tuberculosis (18.5%), fungus ball (10.8%), and lung cancer (5.9%) accounted for most causes of hemoptysis. Computed tomography scan was the most sensitive diagnostic test when employed alone, with positive yield of 93.2%. There were 161 cases of conservative treatment (72.9%), 42 cases of bronchial artery embolization (BAE) (19.0%), and 18 cases of surgery (8.1%). Regarding the amount of hemoptysis, 70 cases, out of 221 cases, were mild (31.5%), 36 cases moderate (16.2%), and 115 cases massive hemoptysis (52.0%). Most of the patients were treated conservatively, but if there was more bleeding present, BAE or surgery was more commonly performed than the conservative treatment (p≤0.0001). In the multivariate model, severe hemoptysis and lung cancer were independently associated with short-term recurrence. BAE was independently associated with long-term recurrence, and lung cancer was associated with in-hospital mortality. The overall in-hospital mortality rate was 11.3%. Conclusion: Hemoptysis is a common symptom with a good prognosis in most cases. However, patients exhibiting massive bleeding or those with malignancy had a poorer prognosis. In-hospital mortality was strongly related to the cause, especially in lung cancer.
한의약 컨텐츠를 가미한 강원도 리조트형 웰니스 프로그램 제안
유준상, 권보인, 이재형 상지대학교 한의학연구소 2023 尙志韓醫論文集 Vol.11 No.1
Objectives: As interest in wellness tourism is increasing in Korea, we sought to propose a program with Korean Medicine Contents for eight resorts in Gangwon-do, which has forests and marine resources. Methods: The authors visited eight designated resorts in Gangwon-do, observed the facilities, and interviewed the people in charge. Questions and answers were asked and answered in the form of a questionnaire regarding any deficiencies in the interviews. Afterwards, the contents were analyzed and a Korean Medicine program suitable for each resort was proposed. Results: A total of 17 Korean Medicine Programs were proposed, of which the meditation/yoga program and diet/drink program tailored to each constitution were proposed to be applicable to all 8 resorts. The rest were proposed considering each resort's facilities, environmental characteristics, and main product programs. Conclusions: It appears that the ‘meditation/yoga program’ and ‘constitutional diet and beverage development’ sectors are programs that can be commonly carried out by all facility companies, and for this purpose, the Sasang constitution test and Korean medicine measurement within the resort in Gangwon-do are used to create a program linked to this. In addition, we believe that efforts to improve the program through verification of efficacy will be necessary in the future
( Hong-joon Shin ),( Min-seok Kim ),( Bo Gun Kho ),( Ha Young Park ),( Tae-ok Kim ),( Cheol-kyu Park ),( Yong-soo Kwon ),( In-jae Oh ),( Yu-il Kim ),( Sung-chul Lim ),( Young- Chul Kim ) 대한결핵 및 호흡기학회 2019 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.127 No.-
Background: Pneumocystis jirovecii pneumonia (PCP) is a fatal respiratory infection frequently associated with immunocompromised (IC) conditions. Although PCP has been reported in non-immunocompromised (non-IC) patients, however, few studies have been conducted. This study was aimed to compare the clinical characteristics and prognosis of PCP in IC and non-IC patients. Methods: We retrospectively analyzed patients who were suspected of having PCP with polymerase chain reaction (PCR) test positive for Pneumocystis jirovecii from January 2013 to May 2019. IC group was classified into human immunodeficiency virus (HIV), hematologic, solid organ tumor, rheumatologic and immunosuppressive agent group. Results: A total 192 PCP cases including 176 IC cases and 16 non-IC cases were analyzed. Patients were older in the non-IC group compared with the IC group (72.5 vs. 62.0, P=0.002). Hematologic malignancy was the most common (47.2%), followed by HIV (14.8%) in the IC group. The interval between test for PCP-PCR and PCP treatment was shorter in the IC group compared with non-IC group (0 [0-3] vs. 4.0 [2.2-7.7] days, P=0.001). In-hospital mortality was not significantly different between IC and non-IC groups (43.2% vs. 62.5%, P=0.189). Age (odds ratio [OR] 1.05; 95% confidence interval [CI] 1.02-1.09; P=0.002) and PaO<sub>2</sub>/FiO<sub>2</sub> (OR 0.99; 95% CI 0.98-1.00; P=0.039) were the prognostic factors for in-hospital mortality in the multivariate logistic regression analysis. There was no significant difference between IC and non-IC group in 6-month survival. However, HIV group had better 6-month survival compared with non- IC group in the subgroup analysis (Hazard ratio 0.16; 95% CI 0.05-0.53; P=0.003]. Conclusion: Patients with PCP in non-IC group were older than IC group, and had similar prognosis as other IC group except HIV group.
Catalytic Pyrolysis of Cellulose over SAPO-11 Using Py-GC/MS
Lee, In-Gu,Jun, Bo Ram,Kang, Hyeon Koo,Park, Sung Hoon,Jung, Sang-Chul,Jeon, Jong-Ki,Ko, Chang Hyun,Park, Young-Kwon Korean Chemical Society 2013 Bulletin of the Korean Chemical Society Vol.34 No.8
The catalytic pyrolysis of cellulose was carried out over SAPO-11 for the first time. Pyrolyzer-gas chromatography/mass spectroscopy was used for the in-situ analysis of the pyrolysis products. The acid sites of SAPO-11 converted most levoglucosan produced from the non-catalytic pyrolysis of cellulose to furans. In particular, the selectivity toward light furans, such as furfural, furan and 2-methyl furan, was high. When the catalyst/cellulose ratio was increased from 1/1 to 3/1 and 5/1, the increase in the quantity of acid sites led to the promotion of deoxygenation and the resultant increase of the contents of light furan compounds. Because furans can be used as basic feedstock materials, the augmentation of the economical value of bio-oil through the catalytic upgrading over SAPO-11 is considerable.
초음파 분무법으로 제작된 In₂O₃: Sn막의 전기적특성
장보현,박희영,권혁정,최인환 중앙대학교 기술과학연구소 1982 기술과학연구소 논문집 Vol.9 No.-
Polycrystalline In₂O₃: Sn films are prepared on the micro slide glass by the spray methed using ultrasonic wave, and their optical and electrical properties are investigated. The starting materials for spray are mixed solution of InCl₃.4H₂O and SnCl₄.5H₂O. The result of the structure analysis using x-ray diffraction pattern and electron micrograph show that the films are polycrystalline cubic structure, and (400) and (222) planes are oriented parallel to the surface of the substrate. The optical transmittance of In₂O₃: Sn film is above 90% at the visible range. The films are assigned to be n-type semiconductor. The range of the carrier concentration lies between ?? and ?? and that of mobilities between 7 and 28 ㎠/V sec.
Analysis of Patients with Hemoptysis in a Tertiary Referral Hospital
Lee, Bo Ram,Yu, Jin Yeong,Ban, Hee Jung,Oh, In Jae,Kim, Kyu Sik,Kwon, Yong Soo,Kim, Yu Il,Kim, Young Chul,Lim, Sung Chul The Korean Academy of Tuberculosis and Respiratory 2012 Tuberculosis and Respiratory Diseases Vol.73 No.2
Background: This study attempted to investigate the main causes of hemoptysis, the type of examinations used for diagnosis, the treatment modalities and outcomes. Methods: A retrospective study was conducted on the medical records of 221 patients admitted to the Chonnam National University Hospital, between January 2005 and February 2010, with hemoptysis. Results: Bronchiectasis (32.6%), active pulmonary tuberculosis (18.5%), fungus ball (10.8%), and lung cancer (5.9%) accounted for most causes of hemoptysis. Computed tomography scan was the most sensitive diagnostic test when employed alone, with positive yield of 93.2%. There were 161 cases of conservative treatment (72.9%), 42 cases of bronchial artery embolization (BAE) (19.0%), and 18 cases of surgery (8.1%). Regarding the amount of hemoptysis, 70 cases, out of 221 cases, were mild (31.5%), 36 cases moderate (16.2%), and 115 cases massive hemoptysis (52.0%). Most of the patients were treated conservatively, but if there was more bleeding present, BAE or surgery was more commonly performed than the conservative treatment ($p{\leq}0.0001$). In the multivariate model, severe hemoptysis and lung cancer were independently associated with short-term recurrence. BAE was independently associated with long-term recurrence, and lung cancer was associated with in-hospital mortality. The overall in-hospital mortality rate was 11.3%. Conclusion: Hemoptysis is a common symptom with a good prognosis in most cases. However, patients exhibiting massive bleeding or those with malignancy had a poorer prognosis. In-hospital mortality was strongly related to the cause, especially in lung cancer.
Ra Hee Kwon,Sang Hyuk Lee,Young Jun Yoon,Jae Hwa Seo,Young In Jang,Min Su Cho,Bo Gyeong Kim,Jung-Hee Lee,In Man Kang 대한전자공학회 2017 Journal of semiconductor technology and science Vol.17 No.2
We have proposed an InGaAs-based gateall-around (GAA) tunneling field-effect transistor (TFET) with a stacked dual-metal gate (DMG). The electrical performances of the proposed TFET are evaluated through technology computer-aided design (TCAD) simulations. The simulation results show that the proposed TFET demonstrates improved DC performances including high on-state current (Ion) and steep subthreshold swing (S), in comparison with a single-metal gate (SMG) TFET with higher gate metal workfunction, as it has a thinner sourcechannel tunneling barrier width by low workfunction of source-side channel gate. The effects of the gate workfunction on Ion, the off-state current (Ioff), and S in the DMG-TFETs are examined. The DMG-TFETs with PNPN structure demonstrate outstanding DC performances and RF characteristics with a higher n-type doping concentration in the In0.8Ga0.2As source-side channel region.
Papain 유도 호흡기 염증모델에서 인삼패독산(人蔘敗毒散)의 항염증 효과
우연주, 유준상, 이동혁, 서진우, 김주희, 권보인 상지대학교 한의학연구소 2023 尙志韓醫論文集 Vol.11 No.1
Objectives: Insampaedok-san and its main components have been used for treatment of fever, joint pain, cough, headache and pain. Using a respiratory inflammation model, we intend to investigate the anti-inflammatory effect and its mechanism of Insampaedok-san. Methods: We induced the actue respiratory inflammatory mouse model by papain treatment. BALB/C mice (female, 8 weeks old) were divided into three groups as follows: saline control (SC): papain treated group (vehicle): papain and Insampaedok-san (200mg/kg) treated group (n=4). To demonstrate the ani-inflammatory effect of Insampaedok-san water extracts, inflammatory cell infiltration was evaluated in bronchoalveolar lavage fluid (BALF) and nasal lavage fluid (NALF). In addition, immunogloblin (Ig)-E level was measured by using ELISA. Results: Insampaedok-san extracts administration decreased inflammatory cell infiltration in BALF and NALF. Especially, eosinophil infiltration was dramatically reduced. Furthermore, total Ig-E level was diminished in BALF and serum by Insampaedok-san administration. Conclusions: Our findings revealed Insampaedok-san extracts have anti-inflammatory effects by inhibiting inflammatory cell, especially eosinophil infiltration and Ig-E level.
선천성 폐 낭성 유선종 기형의 자궁 내 치료 바구니 모양의 도관을 이용한 흉 - 양막강 문합술 2 예
정주연(Joo Yun Chung),원혜성(Hye Sung Won),김소라(So Ra Kim),서미덕(Mi Deok Seo),황보천(Cheon Hwang Bo),김홍권(Hong Kwon Kim),이필량(Pil Ryang Lee),이인식(In Sik Lee),김암(Ahm Kim) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.10
We report a fetal therapy of two cases of type I congenital cystic adenomatoid malformation(CCAM) of the lung. The two fetuses were treated by thoracoamniotic shunting, using a basket-shaped catheter at 25 weeks' and 31 weeks' gestation, respectively. Cystic lesions of the both fetal lung were successfully decompressed after the shunt operation. Healthy babies were delivered at 41 weeks' and 38 weeks' gestation with normal Apgar score. Surgical resections of the affected lobe of the lung in the both babies were performed without complication at 1st and 7th day of birth, respectively. Shunt operation in-utero is considered as a safe and effective therapy for type I CCAM of the fetal lung.