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김범석(BeomSeok Kim),남청도(ChungDo Nam),김유택(YouTaek Kim),김진구(JinGu Kim),이영호(YoungHo Lee) 한국마린엔지니어링학회 2005 한국마린엔지니어링학회 학술대회 논문집 Vol.2005 No.-
The optimum design and the performance analysis software called POSEIDON for the HAWT (Horizontal Axis Wind Turbine) was developed by use of BEMT. The Prandtl's tip loss theory was adopted to consider the blade tip loss. The lift and the drag coefficient of S-809 airfoil were predicted via X-FOIL and also the post stall characteristics of S-809 were estimated by the Viterna's equations. All the predicted aerodynamic characteristics are fairly well agreed with the wind tunnel test results, performed by Sommers in Delft university of technology. The rated power of the testing rotor is 20㎾(FIL-20) at design conditions. The experimental aerodynamic parameters and the X-FOIL data were used for the power prediction of the FIL-20 respectively. The comparison results shows good agreement in power prediction.
수평축 풍력발전용 터빈의 유동해석 및 성능예측에 대한 CFD의 적용성 평가에 관한 연구
김범석(BeomSeok Kim),김정환(JeongHwan Kim),김유택(YouTaek Kim),남청도(ChungDo Nam),이영호(Young Ho Lee) 대한기계학회 2003 대한기계학회 춘추학술대회 Vol.2003 No.4
The purpose of this 3-D numerical simulation is evaluate the application of a commereial CFD code to predict 3-D flow and power characteristics of wind turbines. The experimental approach, which has been main method of investigation, appears to be its limits, the cost increasing with the size of the wind turbines, hence mostly limited to observing the phenomena on rotor blades. Therefore, the use of Computational Fluid Dynamics (CFD) techniques and Navier-Stokes solvers are considered a very serious contender. The flow solver CFX-TASC flow is employed in all computations in this paper. The 3-D flow separation and the wake distribution of 2 and 3 bladed Horizontal Axis Wind Turbines (HAWTs) are compared to Heuristic model and smoke-visualized experimental result by NREL(National Renewable Energy laboratory). Simulated 3-D flow separation structure on the rotor blade is very similar to Heuristic model and the wake structure of the wind turbine is good consistent with smoke-visualized result. The calculated power of the 3 balded rotor by CFD is compared with BEM results by TU-Delft. The CFD results of which is somewhat consist with BEM resulst, under an error less than 10%.
Flow cytometry 기법을 이용한 간 손상 평가법 연구
김철규,신동환,한범석,김준규,조용연,김신희,이근영,안진홍,조미행,고진경,조정식 식품의약품안전청 2001 식품의약품안전청 연보 Vol.5 No.-
화학물질f) 의해 발생하는 간발암 과정중 initiation 단계와 PrOmOtiOH 단계에서 간세포의 증식은 중요한 역할을 한다. 설치류에f·1 혈중 지방감소제나 플라스틱가소제인 phthalate 예스테르 같은 과산화쇼체 증가물질(peroxisome proliferator)을 장기간 투여했을 때, 간 종양이 발껑한다고 알려져 있다.diisodecyl phthalate(DIDP)는 현재 대량생산되어 사용되고 있는 플라스틱 가소제로 주로 풍선, 비닐잉 3, 렌트, 장난감, 직물류의 코.팅 등에 이용되고 있다. 다른 프탈레이트 계통의 가소제와 같이 DIDP 또 할 Pt'c에 혼합되어 이용퇴고 있고 곽산화소체 증가물질로 알려져 있다. 파산화소체 증가물질인 DIDP에 의끌 간세포꼭 DNA함량 변화 및 세포증식 변화를 관찰하고, flolr c반emoter를 이용한 DNA합성지표 및 세포증식지표의 2차원적 분석 기댑을 확립하고자 본 연구를 수행하였다. 430-4509의 Sprague Bawley 랫드를 4 군으로 나누어 DIDP를 0, 300, 600, 1200 mgAg 씩 corn oil에 희석하여 2주간 투여하였다. 극치군에저 대조군자 비교하여 20%, 24%, 33% 정도 간장의 비대에 의한 무게 증가를 나타내었다. 2차원적 리ow cytometer 분석을 이용하여 묘rd린 표지 세포왁 PCNA 발현 양성 간세포의 수와 각각의 세포 주기의 분포는 대조군과 투여군에서 관간 유의차를 나타내지 않았다. BrdU 표지 세포와 PCNA 발현 양성 세포가 대조군과 비교하여 투여굴에서 유의차를 나타내지 않은 것은 DIDP의 영향보 다 성장에 의한 간세포 증식이 활발하여 나타난 결과라 생각된다. 본 실험에서 과산화소체 증가물질인 DIDP의 반닦투여에 의한 간세포의 DNA함쏠 변화 및 세포증식 변후에 미치는 유의차는 관찰되지 않았고, 포르말린 고정한 표본이나 신선하게 분리한 간세포에서 flow c?·tometer를 이용한 DNA합성지표 및 세포증식지표의 2차원적 분석 기댑은 유해물질의 세포증식에 대한 영향을 독성병리학적 관점에서 평가할수 있는 유용글 지표라 생각한다. Peroxisome proliferators are belived to induce liver tumors in rodents due to sustained increase in cell proliferation and oxidative stress resulting from the induction of peroxisomal enzymes. Diisodecyl phthalate(DIDP), a plasticizer produced in a large amount, is use for balloon, ink, tent, toys, coated fabrics and wire cable. Liver effects, including indications of an increase in certain subcellular structure(peroxisomes), occurred in rats fed DIDP. The objective of this study was to conduct a analysis of the changes in cell cycle and rat liver DNA synthesis after treatment with a peroxisome proliferator. Immunofluorescent detection of proliferating cell nuclear antigen (PCNA) and bromodeoxyuridine (BrdU) incorporation into DAN during S phase were used to assess rat heapatocyte proliferation in vivo during administration of DIDP, a known peroxisome proliferator in rodents. Sprague Dawley rat at 430-450g were exposed to 0, 300, 600 and 1200mg/kg body weight DIDP in corn oil for 2 weeks and fed a commercial diet. DIDP treated rats showed marked hepatomegaly wih liver weight increased approximately 20, 24, 33% in groups of 300, 600, 1200 mg/kg, respectively. Isolated liver nuclei labeled with fluorescein isothiocyanate (FITC)-anti-BrdU/PI and FITC-anti-PCNA/PI were analyzed for S-phase kinetics using flow cytometry. BrdU labeling index, PCNA lebeling index and distribution of cells in G_(0)-G₁, S phase, G₂-M did not differ significantly from controls. S-phase cells constitute approximately 35% of the total population in control rat liver, a significantly higher number than reported earlier. The use of relatively young rat in the present study might have led to high levels of S-phase nuclei in control rats and too no differences in distribution of cells. It is reasonable to conclude that the marked hepatomegaly, associate with DIDP treatment, that the flow cytometric analysis of isolated nuclei from formalin fixed samples and freshly isolated hepatocytes and potentially other useful markers would provide a useful tool for retrospective assessment of the cell proliferation in toxicological pathology.
A Distributed Coexistence Mitigation Scheme for IoT-Based Smart Medical Systems
( Beomseok Kim ) 한국정보처리학회 2017 Journal of information processing systems Vol.13 No.6
Since rapidly disseminating of Internet of Things (IoT) as the new communication paradigm, a number of studies for various applications is being carried out. Especially, interest in the smart medical system is rising. In the smart medical system, a number of medical devices are distributed in popular area such as station and medical center, and this high density of medical device distribution can cause serious performance degradation of communication, referred to as the coexistence problem. When coexistence problem occurs in smart medical system, reliable transmitting of patient’s biological information may not be guaranteed and patient’s life can be jeopardized. Therefore, coexistence problem in smart medical system should be resolved. In this paper, we propose a distributed coexistence mitigation scheme for IoT-based smart medical system which can dynamically avoid interference in coexistence situation and can guarantee reliable communication. To evaluate the performance of the proposed scheme, we perform extensive simulations by comparing with IEEE 802.15.4 MAC protocol which is a traditional low-power communication technology.