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Everaldo Silvino dos Santos,Carlos Eduardo de Araújo Padilha,Nathália Kelly de Araújo,Domingos Fabiano de Santana Souza,Jackson Araújo de Oliveira,Gorete Ribeiro de Macedo 한국화학공학회 2016 Korean Journal of Chemical Engineering Vol.33 No.9
A phenomenological model was used to describe sequentially the three steps (flowthrough, washing and elution) of expanded bed adsorption chromatography for recovery of chitosanases from Bacillus cereus. Additionally, a hybrid strategy for model parameter estimation was carried out using particle swarm optimization and Gauss-Newton algorithms. The model was validated with independent experimental data and the statistical criteria (χ 2 and mean squared error tests) showed that the hybrid strategy was more promising than just the heuristic method. With the calibrated model, surface response methodology was applied to obtain the optimal operational conditions, and experiments were performed to confirm these results. Overall, a value of 41.08% for yield was obtained using 700mM NaCl during elution. In summary, all approach employed in this work was relevant for maximizing the yield of the chromatographic process.
Impact of the Fourth Industrial Revolution on the Health Sector: A Qualitative Study
João António Gomes de Melo e Castro e Melo,Nuno Miguel Faria Araújo 대한의료정보학회 2020 Healthcare Informatics Research Vol.26 No.4
Objectives: The Fourth Industrial Revolution is changing the way health is understood, transforming the methods of treatmentand diagnosis as well as the relationship between health professionals and patients and altering the management andorganization of health systems. The main objective of this study was to explore the impact that the Fourth Industrial Revolutionis having on the health sector. Methods: Conducting interviews consisting of four questions with 10 professionals whohad experience working in the health sector to gain their insights and to obtain information to meet the general objective ofthe study as well as its specific objectives. Results: From the analysis of the respondents’ responses, it was possible to createfive dimensions developed by the topics most addressed by respondents, namely, impact on healthcare efficiency and effectiveness,impact on government action, impact on human resources, impact on health system organization, and financialimpact on the health sector. Conclusions: Although the Fourth Industrial Revolution is still at an early stage, it has been concludedthat it is having a major positive impact on the health sector. For the effective and efficient implementation of thesedisruptive technologies, a global interaction between governments, health professionals, stakeholders, and society is essentialto make this change possible.
de Araújo Amanda Dias,de Barros Pimentel Maria do Carmo,Santos Camila da Silva,da Silva Roberto Afonso,Cadena Pabyton Gonçalves,da Silva Nicácio Henrique,Gusmão Norma Buarque,Sleifer Bruno Alonso,da S 경희대학교 융합한의과학연구소 2021 Oriental Pharmacy and Experimental Medicine Vol.21 No.4
The focus of this study was to evaluate the presence and type of carbohydrates and phenolic molecules inaqueous extract (Aq-E) of Alternanthera brasiliana fresh leaves and its antioxidant and antimicrobial activities and cytotoxicity in vitro. The amount and types of the carbohydrates were measured by colorimetric and TLC methods. Phenolic compounds was detected by colorimetric assay and analysed by HPLC profiles. The antioxidant activity was evaluated by ABTS and Phosphomolybdenum methods. Antimicrobial activity was tested by microdilution method using microorganism models and antibiotic as positive control, the cytotoxicity in vitro was tested using Artemia salina. The results showed the presence of high amount of total sugars and uronic acids. TLC chromatograms showed mainly D-glucose, D-fructose, oligosaccharides and uronic acids in the Aq-E and a sugar alcohol in the methanolic extract. The colorimetric determination showed high concentration of phenolic compounds, which were visualised on the HPLC profiles, such as chemical markers of the Amaranthaceae family and several phenolic acids and flavonoids. The Aq-E demonstrated optimal antioxidant activities. The most important results were the excellent antibacterial and bactericidal activities against Mycobacterium megmatis (MIC = 15.6 µg/mL and MBC = 1000 µg/mL) and antimicrobial activity against Candida albicans (MIC = 31.2 µg/mL) and low cytotoxicity. Further possibilities for this plant extract will be to improve the pharmacological potential for developing new herbal medicines and possibly to study its association to allopathic antibiotics for prevention or treatment of infection diseases.
Negative neuromuscular and functional repercussion of forced swimming after axonotmesis
Júlia Araújo de Moura,Jaqueline de Morais,Samara Maria Neves Barbosa,Marcílio Coelho Ferreira,Ivo Vieira de Sousa Neto,Hércules Ribeiro Leite,Murilo Xavier Oliveira,Thaís Peixoto Gaiad,Ana Paula Santo 한국운동재활학회 2022 JER Vol.18 No.3
Márcia Araújo Motta,Jeonghwa Jang,Mijeong Kim,Eunsil Choi,Jiyoung Kim,Anna Carolina Torracca-Rocha,Won-Sik Kong,Arailde Fontes Urban 한국버섯학회 2017 한국버섯학회지 Vol.15 No.2
The choice of strain, substrate, and environmental conditions are fundamental factors that determine the ability of a fungus to develop and produce mushrooms with high quality. The objective of this study was to compare the strains of Lentinula edodes and Ganoderma lucidum originated from South Korea and Brazil in relation to their vegetative development in different culture media, to obtain isolates with high quality. The strains of the two mushroom species from Brazil and South Korea grew slowly, possibly because of abiotic factors or storage technique used. However, it may be concluded that temperature, humidity, light, pH, and nutrients from the substrate, if not regulated appropriately may affect the vegetative species.
Effect of Acupressure on Dental Anxiety in Children: a Pilot Study for a Randomized Clinical Trial
Soares Maria Eliza Consolação,Araújo Alessandra de Souza,Pinto Isabela Carvalhaes Lagares,Barbosa Luiza Silveira Araújo,Borsatto Maria Cristina,Galo Rodrigo 사단법인약침학회 2022 Journal of Acupuncture & Meridian Studies Vol.15 No.5
Background: Anxiety is an important problem in children in dental clinics. Acupressure may be a useful tool to assist in dental procedures in anxious children. Objectives: This pilot study was performed to examine the effects of acupressure on dental anxiety in children undergoing restorative procedures. Methods: Fourteen children aged 7-10 years and with at least one primary molar with caries on the dentine were included in the study. The participants also needed to score at least one point on the modified Venham Picture Test (VPTm) for the determination of anxiety. The children were randomly allocated to two groups: group A — non-documented points for the reduction of anxiety and induction of relaxation; group B — documented points (EX-HN3, Shen Men of auricular acupuncture). The anxiety scale was administered on three occasions: prior to the application of acupressure; immediately after sitting in the dental chair to undergo restorative treatment; and after removal of acupressure at the end of the restorative procedure. Heart rate (HR) was measured when each child sat in the dental chair, after the removal of carious tissue, and after the removal of acupressure. Results: After the procedure, HR (as an indicator of anxiety) was statistically significantly lower in group B than group A (p = 0.02). However, there was no significant difference between the groups regarding anxiety before and during the restorative procedure (VPTm and HR: p > 0.05). Conclusion: The children who received acupressure on documented points for the reduction of anxiety had a significantly lower HR after the restorative procedure. No significant between-group difference was found regarding anxiety measured using a psychometric evaluation (VPTm).
HUGO VALENÇA DE ARAÚJO,JOSÉ VICENTE HALLAK D'ANGELO 대한설비공학회 2014 International Journal Of Air-Conditioning and Refr Vol.22 No.4
Alcoholic fermentation is one of the most important stages in industrial ethanol productionprocess, involving a biochemical and exothermic reaction. Sometimes cooling towers are notcapable of supplying a cold utility with a temperature low enough to maintain the fermentativemedium temperature in a desirable range. Absorption Refrigeration Systems (ARS) appears to bea good alternative to obtain the necessary refrigeration for the fermentation process. The aim ofthe present paper was to carry out a thermodynamic analysis of ARS, evaluating their performancethrough the First and Second Laws of Thermodynamics. ARS with different con¯gurationswere studied (single-effect and double-effect with series, parallel and reverse parallel flows), all ofthem operating with water/lithium bromide mixture as working pair, under different operatingconditions in order to satisfy the cooling load required by an industrial alcoholic fermentationprocess. Another objective of this paper was to investigate the risk of LiBr crystallization, whichcan result in scaling formation, with the aid of the solid–liquid phase equilibrium curve of H2O/LiBr mixture. Among the double-effect con¯gurations studied, it was observed that series flow presents the more signi¯cant crystallization risk, which represents a limit to improve its First andSecond Law performances. It was veri¯ed that the Second Law performance for the single-anddouble-effect ARS analyzed are similar, but their First Law performance are considerably different. This is due to the amount and quality of the heat consumed in the first effect generators ofthese systems. For a base case studied, First Law performance measured by coefficient of performance(COP) of double-effect ARS is 72% greater than the one for single-effect, while forSecond Law performance, measured by exergetic efficiency, an increase of 5% was observed.
Fernandes Thalita,Silva Sidinei,Araújo Antonio 한국화학공학회 2024 Korean Journal of Chemical Engineering Vol.41 No.3
Estimating kinetic parameters in heterogeneous solid catalytic reaction networks is known to being a diffi cult task. This work aims at proposing a down-to-earth methodology to obtain kinetic parameters from numerical experiments. We present three techniques: a multivariable linear regression model, a stochastic metamodeling, and an optimized Kriging metamodel connected to a least-squares method. We consolidate the methodology in two diff erent applications. The fi rst one is a process with few components in two reactions from where it was possible to acquire the reaction rate equations that fi tted literature data. The second one is a complex industrial reaction network. The results showed that even if the candidate proposed reaction rate equations do not fi t the experiments, it is possible to construct a mathematical metamodel that conforms to the behavior of the components. Statistical tests showed that in both cases the proposed models successfully fi t the experimental data.
Infodemic: The New Informational Reality of the Present Times
Carlos Alberto Ávila Araújo 한국과학기술정보연구원 2022 Journal of Information Science Theory and Practice Vol.10 No.1
This text discusses elements and characteristics of contemporary informational reality, that is, the ways of producing, circulating, organizing, using, and appropriating information in the current context. Initially, seven terms and concepts used to describe this reality are discussed: fake news, false testimonials, hate speech, scientific negationism, disinformation, post-truth, and infodemic. Next, an attempt is made to present a framework for such phenomena as an object of study in information science. Therefore, this scenario is characterized based on the three main models of information science study: physical, cognitive, and social. The contribution of each of them to the study of contemporary informational reality is analyzed, identifying aspects such as the bubble effect, clickbaits, confirmation bias, cults of amateurism, and post-truth culture. Finally, it presents the discussion of a possible veritistic turn in the field, in order to think about elements not covered so far by information science in its task and challenge of producing adequate understanding and diagnoses of current phenomena. In conclusion, it is argued that only accurate and comprehensive diagnoses of such phenomena will allow information science to develop services and systems capable of combating their harmful effects.