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- 저자 : Fernandes Thalita (검색결과 2 건)
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Fernandes Thalita,Silva Sidinei,Araújo Antonio 한국화학공학회 2024 Korean Journal of Chemical Engineering Vol.41 No.3
Estimating kinetic parameters in heterogeneous solid catalytic reaction networks is known to being a diffi cult task. This work aims at proposing a down-to-earth methodology to obtain kinetic parameters from numerical experiments. We present three techniques: a multivariable linear regression model, a stochastic metamodeling, and an optimized Kriging metamodel connected to a least-squares method. We consolidate the methodology in two diff erent applications. The fi rst one is a process with few components in two reactions from where it was possible to acquire the reaction rate equations that fi tted literature data. The second one is a complex industrial reaction network. The results showed that even if the candidate proposed reaction rate equations do not fi t the experiments, it is possible to construct a mathematical metamodel that conforms to the behavior of the components. Statistical tests showed that in both cases the proposed models successfully fi t the experimental data.
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Blood level of adipokines and nutritional status variables in adolescent pregnancy
Mirela Douradinho Fernandes,Silvia Daher,Luciana Moraes de Sousa,Indiomara Baratto,Thalita Frutuoso Lobo,Edward Araujo Júnior,Cristina Aparecida Falbo Guazzelli 대한산부인과학회 2020 Obstetrics & Gynecology Science Vol.63 No.6
ObjectiveTo evaluate the serum levels of adiponectin and leptin and their relationship with nutritional variables duringpregnancy in adolescents. MethodsThis prospective cohort study evaluated eutrophic pregnant adolescents (body mass index [BMI], 18.5–24.9 kg/m2) during the 3 gestational trimesters (first, 10–14 weeks; second, 24–28 weeks; and third, 30–34 weeks). Serumadiponectin and leptin concentrations were measured using the enzyme-linked immunosorbent assay method. Therelationship of these adipokines with the pre-gestational BMI, gestational weight gain, weight at the time of samplecollection, and newborn weight were evaluated. Analysis of variance and the Kruskal-Wallis test were used forstatistical analysis. ResultsThe study group comprised 62 pregnant adolescents. The serum concentration of adiponectin showed a significantdifference between the first and third trimesters (P=0.003), which decreased during pregnancy, but unrelated tonutritional variables. Serum leptin levels increased throughout the pregnancy (P<0.0001) and showed a positivecorrelation with pre-gestational BMI, total weight gain, pregnancy weight at the time of sample collection, andnewborns’ weight. ConclusionSerum levels of adiponectin and leptin vary inversely throughout pregnancy. This pattern in adolescents is similar tothat observed in adults. Moreover, leptin concentrations increased throughout pregnancy, and they were positivelycorrelated with all variables evaluated.
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