Pour une approche moniste et éthique du sujet aphasique

Armelle Jacquet-Andrieu,Kalina YANEVA-NEDEVA 고려대학교 응용문화연구소 2018 에피스테메 Vol.0 No.20

After a short presentation of Medical Ethics and its definitions, we approach this paradigm on a general level, from a brief commentary on the Hippocratic Oath, which is still relevant today. All care actions of health professionals are part of the ethics of this oath. So we think about the problem of health ethics, evoking the multiple disability paradigm and chronic disease: more specifically, we consider the sudden onset of aphasia and the lived experience of the aphasic subject, usually an adult. Hospitalized for three months, on average, he follows a "language rehabilitation" or "cognitive remediation", for at least three years, conceived as a tutorage, in the didactic sense of the term, specifically adapted to adulthood. To support this multidisciplinary reflection, we use the philosophy of Kant, educator and didactician, we study the concepts of respect and dignity, in order to provide to the aphasic person the care best adapted to his state and his psychology. Après une courte présentation de l’éthique médicale et de ses définitions, nous abordons ce paradigme sur un plan général, à partir d’un bref commentaire du Serment d’Hippocrate, toujours d’actualité. Il apparaît que toutes les actions des professionnels de santé s’inscrivent dans l’éthique de ce serment. Nous réfléchissons donc au problème de l’éthique en santé, en évoquant le paradigme du polyhandicap et de l’atteinte chronique : plus spécifiquement, nous considérons l’aphasie d’installation soudaine et le vécu du sujet aphasique, généralement un adulte. Hospitalisé pendant trois mois, en moyenne, il suit une « rééducation du langage » ou « remédiation cognitive », durant trois ans, au moins, conçue comme un préceptorat, au sens didactique du terme, spécifiquement adapté à l’âge adulte. Pour étayer cette réflexion pluridisciplinaire, nous avons recours à la philosophie de Kant, éducateur et didacticien, nous étudions les concepts de respect et de dignité, afin d’apporter à la personne aphasique les soins les mieux ajustés à son état et à sa psychologie.

Comparison of 2-Dimensional and 3-Dimensional Conformal Treatment Plans in Gastric Cancer Radiotherapy

Adas, Yasemin Guzle,Andrieu, Meltem Nalca,Hicsonmez, Ayse,Atakul, Tugba,Dirican, Bahar,Aktas, Caner,Yilmaz, Sercan,Akyurek, Serap,Gokce, Saban Cakir,Ergocen, Salih Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.17

Background: Postoperative chemoradiotherapy is accepted as standard treatment for stage IB-IV, M0 gastric cancer. Radiotherapy (RT) planning of gastric cancer is important because of the low radiation tolerance of surrounding critical organs. The purpose of this study was to compare the dosimetric aspects of 2-dimensional (2D) and 3-dimensional (3D) treatment plans, with the twin aims of evaluating the adequacy of 2D planning fields on coverage of planning target volume (PTV) and 3D conformal plans for both covering PTV and reducing the normal tissue doses. Materials and Methods: Thirty-six patients with stage II-IV gastric adenocarcinoma were treated with adjuvant chemoradiotherapy using 3DRT. For each patient, a second 2D treatment plan was generated. The two techniques were compared for target volume coverage and dose to normal tissues using dose volume histogram (DVH) analysis. Results: 3DRT provides more adequate coverage of the target volume. Comparative DVHs for the left kidney and spinal cord demonstrate lower radiation doses with the 3D technique. Conclusions: 3DRT produced better dose distributions and reduced radiation doses to left kidney and spinal cord compared to the 2D technique. For this reason it can be predicted that 3DRT will result in better tumor control and less normal tissue complications.

산처리 공정에 따라 추출한 돈피 젤라틴의 이화학적 특성에 관한 연구

염건웅,민상기,Yeom Geun-Woong,J Andrieu,Min Sang-Gi 한국축산식품학회 2004 한국축산식품학회지 Vol.24 No.3

The objective of this study was to investigate the physicochemical characteristics of gelatin extracted from pork skin under soaking in various acid solutions (lactic acid, acetic acid, and citric acid). Gelatin sol was extracted at 8$0^{\circ}C$, frozen at -2$0^{\circ}C$ and lyophilized it for 3 days to be completely dried in freeze drying unit. In the evaluation of gelatin quality, gelatin soaked in citric acid showed higher L- and a-values than those of any other gelatin (p<0.05). Gelatin treated by acetic acid showed the highest gel strength, cohesiveness, and brittleness. The content of hydroxyproline amino acid in gelatin treated by acetic acid was larger than one of gelatin treated in lactic and citric acid in order. From the experimental results, the highest quality of gelatin in all of period, which was soaked in acetic acid and lactic acid, has a more good quality than gelatin soaked in citric acid. 본 연구는 gelatin의 생산공정에서 각종 산 처리가 최종 gelatin의 품질에 어떤 영향을 주는지를 평가함으로써 양질의 gelatin을 생산하는데 기초를 제공하고자 하였다. Gelatin gel의 물성은 lactic acid로 처리한 gelatin이 높은 hardness, cohesiveness, brittleness를 나타내었고 다음으로는 citric acid, acetic acid 순으로 나타났다. Gelatin의 색도는 citric acid, 처리한 gelatin이 acetic acid나 lactic acid로 산침한 젤라틴 보다 높은 명도를 나타냈다. a-value는 acetic acid로 산침한 gelatin이 가장 높게 나타났으며 황색도를 나타내는 b-value는 lactic > acetic acid > citric acid 순으로 높게 나타났다. Gelatin의 점도를 측정한 결과 전단속도(shear rate)에 대한 전단응력(shear stress)의 관계는 모두 전단속도가 증가함에 따라 전단응력이 증가하는Newton성 유체로 판단되었다. 그 기울기는 acetic acid로 산침한 것이 가장 높게 나타났으며 lactic acid, citric acid 순으로 높게 나타났다. Gelatin내의 hydroxyproline 함량을 살펴보면 acetic acid(0.186 g/100 g sample)로 가장 높은 수치를 나타나며 다음으로 lactic acid, citric acid 순으로 나타났다. 그러나, sample중 crude protein 함량을 비교하면 acetic acid(68.74%), lactic acid(80.08%), citric acid(85.47%)로 나타났다. 이것은 gelatin의 열수 추출시 가장 작게 용출된 acetic acid가 가장 높은 collagenous connective tissue 함량(1.35 g/100g)을 나타내었다.

Modeling of the Reactive Infrared Drying of a Model Water-Based Epoxy-Amine Painting Coated on Iron Support with Experimental Validation

Denise Blanc,Pierre Laurent,Julien Andrieu,Jean Francois Gerard 대한기계학회 1998 Heat transter conference Vol.5 No.1

Evaluation of the Radiation Pneumonia Development Risk in Lung Cancer Cases

Yilmaz, Sercan,Adas, Yasemin Guzle,Hicsonmez, Ayse,Andrieu, Meltem Nalca,Akyurek, Serap,Gokce, Saban Cakir Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.17

Background: Concurrent chemo-radiotherapy is the recommended standard treatment modality for patients with locally advanced lung cancer. The purpose of three-dimensional conformal radiotherapy (3DCRT) is to minimize normal tissue damage while a high dose can be delivered to the tumor. The most common dose limiting side effect of thoracic RT is radiation pneumonia (RP). In this study we evaluated the relationship between dose-volume histogram parameters and radiation pneumonitis. This study targeted prediction of the possible development of RP and evaluation of the relationship between dose-volume histogram (DVH) parameters and RP in patients undergoing 3DCRT. Materials and Methods: DVHs of 41 lung cancer patients treated with 3DCRT were evaluated with respect to the development of grade ${\geq}2$ RP by excluding gross tumor volume (GTV) and planned target volume (PTV) from total (TL) and ipsilateral (IPSI) lung volume. Results: Were admitted statistically significant for p<0.05. Conclusions: The cut-off values for V5, V13, V20, V30, V45 and the mean dose of TL-GTV; and V13, V20,V30 and the mean dose of TL-PTV were statistically significant for the development of Grade ${\geq}2$ RP. No statistically significant results related to the development of Grade ${\geq}2$ RP were observed for the ipsilateral lung and the evaluation of PTV volume. A controlled and careful evaluation of the dose-volume histograms is important to assess Grade ${\geq}2$ RP development of the lung cancer patients treated with concurrent chemo-radiotherapy. In the light of the obtained data it can be said that RP development may be avoided by the proper analysis of the dose volume histograms and the application of optimal treatment plans.

COMMISSIONING RESULT OF THE KSTAR HELIUM REFRIGERATION SYSTEM

DONG-SEONG PARK,HYUN-SIK CHANG,JAE-JOON JOO,KYUNG-MO MOON,KWANG-WOON CHO,YANG-SOO KIM,JOO-SHIK BAK,MYEON-CHUL CHO,IL-KEUN KWON,FREDERIC ANDRIEU,JEROME BEAUVISAGE,STEPHANE DESAMBROIS,ERIC FAUVE,MICHEL 한국원자력학회 2008 Nuclear Engineering and Technology Vol.40 No.6

To keep the superconducting (SC) magnet coils of KSTAR at proper operating conditions, not only the coils but also other cold components, such as thermal shields (TS), magnet structures, SC bus-lines (BL), and current leads (CL) must be maintained at their respective cryogenic temperatures. A helium refrigeration system (HRS) with an exergetic equivalent cooling power of 9 kW at 4.5 K without liquid nitrogen (LN₂) pre-cooling has been manufactured and installed. The main components of the KSTAR helium refrigeration system (HRS) can be classified into the warm compression system (WCS) and the cryogenic devices according to the operating temperature levels. The process helium is compressed from 1 bar to 22 bar passing through the WCS and is supplied to cryogenic devices. The main components of cryogenic devices are consist of cold box (C/B) and distribution box (D/B). The C/B cool-down and make the various cryogenic helium for the KSTAR Tokamak and the various cryogenic helium is distributed by the D/B as per the KSTAR requirement. In this proceeding, we will present the commissioning results of the KSTAR HRS. Circuits which can simulate the thermal loads and pressure drops corresponding to the cooling channels of each cold component of KSTAR have been integrated into the helium distribution system of the HRS. Using those circuits, the performance and the capability of the HRS, to fulfill the mission of establishing the appropriate operating condition for the KSTAR SC magnet coils, have been successfully demonstrated.

COMMISSIONING RESULT OF THE KSTAR HELIUM REFRIGERATION SYSTEM

Park, Dong-Seong,Chang, Hyun-Sik,Joo, Jae-Joon,Moon, Kyung-Mo,Cho, Kwang-Woon,Kim, Yang-Soo,Bak, Joo-Shik,Cho, Myeon-Chul,Kwon, Il-Keun,Andrieu, Frederic,Beauvisage, Jerome,Desambrois, Stephane,Fauve, Korean Nuclear Society 2008 Nuclear Engineering and Technology Vol.40 No.6

To keep the superconducting (SC) magnet coils of KSTAR at proper operating conditions, not only the coils but also other cold components, such as thermal shields (TS), magnet structures, SC bus-lines (BL), and current leads (CL) must be maintained at their respective cryogenic temperatures. A helium refrigeration system (RRS) with an exergetic equivalent cooling power of 9 kW at 4.5 K without liquid nitrogen ($LN_2$) pre-cooling has been manufactured and installed. The main components of the KST AR helium refrigeration system (HRS) can be classified into the warm compression system (WCS) and the cryogenic devices according to the operating temperature levels. The process helium is compressed from 1 bar to 22 bar passing through the WCS and is supplied to cryogenic devices. The main components of cryogenic devices are consist of cold box (C/B) and distribution box (D/B). The C/B cool-down and make the various cryogenic helium for the KSTAR Tokamak and the various cryogenic helium is distributed by the D/B as per the KSTAR requirement. In this proceeding, we will present the commissioning results of the KSTAR HRS. Circuits which can simulate the thermal loads and pressure drops corresponding to the cooling channels of each cold component of KSTAR have been integrated into the helium distribution system of the HRS. Using those circuits, the performance and the capability of the HRS, to fulfill the mission of establishing the appropriate operating condition for the KSTAR SC magnet coils, have been successfully demonstrated.

Search for associated production of charginos and neutralinos in the trilepton final state using 2.3 fb⁻¹ of data

Abazov, V.M.,Abbott, B.,Abolins, M.,Acharya, B.S.,Adams, M.,Adams, T.,Aguilo, E.,Ahsan, M.,Alexeev, G.D.,Alkhazov, G.,Alton, A.,Alverson, G.,Alves, G.A.,Anastasoaie, M.,Ancu, L.S.,Andeen, T.,Andrieu, Elsevier 2009 Physics letters: B Vol.680 No.1

<P><B>Abstract</B></P><P>We report the results of a search for associated production of charginos and neutralinos using a data set corresponding to an integrated luminosity of 2.3 fb<SUP>−1</SUP> collected with the DØ experiment during Run II of the Tevatron proton–antiproton collider. Final states containing three charged leptons and missing transverse energy are probed for a signal from supersymmetry with four dedicated trilepton event selections. No evidence for a signal is observed, and we set limits on the product of production cross section and leptonic branching fraction. Within minimal supergravity, these limits translate into bounds on <SUB>m0</SUB> and <SUB>m1/2</SUB> that are well beyond existing limits.</P>