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      • SCIESCOPUSKCI등재

        Effect of oxidizing treatment on electrocatalytic activity of boron‑doped amorphous carbon thin films

        Chen‑Song Wang,Ni Suo,Hao Huang,Aimin Wu,Guo‑Zhong Cao,Gui‑Feng Zhang 한국탄소학회 2019 Carbon Letters Vol.29 No.5

        Boron-doped amorphous carbon (BDAC) thin films with a regular oxygen reduction reaction (ORR) catalytic activity were synthesized in a hot filament chemical vapor deposition device using a mixture of CH4 and H2 as a gas source and B2O3 as a boron source and then oxidized in air at 380–470 °C for 15–75 min. Scanning electron microscope, transmission electron microscope, Raman spectroscopy, X-ray photoelectron spectroscopy, and electrochemical tests were used to characterize the physical and electrochemical properties of the BDAC catalysts. It was concluded that the BDAC catalyst oxidized at 450 °C for 45 min showed the best ORR catalytic activity in alkaline medium. The oxygen reduction potential and the transfer electron number n, respectively, are − 0.286 V versus Ag/AgCl and 3.24 from the rotating disk electrode experiments. The treated carbon film has better methanol resistance and stability than the commercial Pt/C catalyst.

      • KCI등재

        Effect of oxidizing treatment on electrocatalytic activity of boron-doped amorphous carbon thin films

        Wang Chen-Song,Suo Ni,Huang Hao,Wu Ai-min,Cao Guo-Zhong,Zhang Gui-Feng 한국탄소학회 2019 Carbon Letters Vol.29 No.5

        Boron-doped amorphous carbon (BDAC) thin films with a regular oxygen reduction reaction (ORR) catalytic activity were synthesized in a hot filament chemical vapor deposition device using a mixture of CH4 and H2 as a gas source and B2O3 as a boron source and then oxidized in air at 380–470 °C for 15–75 min. Scanning electron microscope, transmission electron microscope, Raman spectroscopy, X-ray photoelectron spectroscopy, and electrochemical tests were used to characterize the physical and electrochemical properties of the BDAC catalysts. It was concluded that the BDAC catalyst oxidized at 450 °C for 45 min showed the best ORR catalytic activity in alkaline medium. The oxygen reduction potential and the transfer electron number n, respectively, are − 0.286 V versus Ag/AgCl and 3.24 from the rotating disk electrode experiments. The treated carbon film has better methanol resistance and stability than the commercial Pt/C catalyst.

      • KCI등재

        Relation between Quantum Entanglement and the Berry Phase in Systems of Two Interacting Qubits

        Ai Min Chen,Yao Heng Su,Sam Young Cho 한국물리학회 2010 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.57 No.4

        Quantum entanglement and the Berry phase are investigated in systems of two interacting qubits. The interaction between the qubits is considered as an XXZ-type exchange interaction, which can make the qubits entangled. A slowly rotating external field is also applied for the Berry phases of the system within the adiabatic theorem. Analytic expressions for the eigenvalues and eigen-wavefunctions of the system are obtained in terms of the interaction parameters and external fields. The competition between the interaction and the external field is shown to be determine a characteristic behavior of the Berry phases and concurrences. The relation between the Berry phase and entanglement for the eigenstates of the system is found to be unique as the interaction strengths vary. The way in which anisotropy of the interaction reveals the unique relations between the Berry phases and the entanglements is discussed.

      • KCI등재

        Minimum 2-Year Experience with Magnetically Controlled Growing Rods for the Treatment of Early-Onset Scoliosis: A Systematic Review

        Ai-Min Wu,Jason Pui Yin Cheung,Kenneth Man Chee Cheung,Jia-Liang Lin,Hai-Ming Jin,Dong Chen,Xiang-Yang Wang,Jie Zhao,Kenny Yat Hong Kwan 대한척추외과학회 2019 Asian Spine Journal Vol.13 No.4

        Magnetically controlled growing rods have been used to treat early-onset scoliosis for the last 9 years; however, few studies have been published, with only short-term follow-up. The aim of the present study is to systematically review the outcomes of magnetically controlled growing rods in the treatment of early-onset scoliosis with a minimum of 2-year follow-up. Studies were included if patients with early-onset scoliosis (scoliosis diagnosed before 10 years of age) underwent implantation of magnetically controlled growing rods with a minimum of 2-year follow-up. The literature review and data extraction followed the established preferred reporting items for systematic review and meta-analysis guidelines. Data of distraction frequency, number of distractions, distracted length, Cobb angle, kyphosis, T1–T12 length, and T1–S1 length preoperatively, postoperatively, and at final follow-up were collected. Data regarding complications and unplanned reoperations were also extracted. The mean values of these parameters were calculated, or pooled meta-analysis was performed if available. Ten articles were included in this systematic review, with a total of 116 patients and a follow-up period between 23 and 61 months. The mean preoperative Cobb angle and kyphosis angle were 60.1° and 38.0°, respectively, and improved to 35.4° and 26.1° postoperatively. At final follow-up, the Cobb and kyphosis angles were maintained at 36.9° and 36.0°, respectively. The average preoperative T1–T12 and T1–S1 lengths were 180.6 mm and 293.6 mm, respectively, and increased to 198.3 mm and 320.3 mm postoperatively. T1–T12 and T1–S1 lengths were 212.3 mm and 339.3 mm at final follow-up, respectively. The overall rate of patients with complications was 48% (95% confidence interval [CI], 0.38–0.58) and unplanned reoperation 44% (95% CI, 0.33–0.55) after sensitivity analysis. The current evidence from different countries with a minimum of a 2-year follow-up suggests that magnetically controlled growing rods are an effective technique to treat pediatric scoliosis and promote spine growth. However, nearly half of patients still developed complications or required unplanned reoperations.

      • KCI등재

        Formula for the Total Stopping Power from 2 keV to 10 keV for a Metal

        Ai-Gen Xie,Min Lai,Chen-Yi Zhang 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.62 No.1

        On the basis of the range-energy relationship, the relationships (L<sub>2−10</sub>) among the total stopping power from 2 keV to 10 keV for a metal (S<sub>2−10</sub>), the energy exponent (n<sub>2−10</sub>), the primary energy at the surface (W<sub>p0</sub>), and the parameter (A<sub>2−10</sub>) were deduced. In addition, the relationships (L<sub>10−30</sub>) among the total stopping power from 10 keV to 30 keV for a metal (S<sub>10−30</sub>), the energy exponent (n<sub>10−30</sub>), Wp0 and the parameter (A<sub>10−30</sub>) were obtained. According to some relationships between the parameters of the secondary electron yield from 2 keV to 10 keV for a metal (δ<sub>2−10</sub>), the composition of the secondary electron yield from 10 keV to 30 keV for a metal (δ<sub>10−30</sub>), L<sub>2−10</sub>, and L<sub>10−30</sub>, the universal formula for expressing S<sub>2−10</sub> as a function of S<sub>10−30</sub>, δ<sub>2−10</sub>, δ<sub>10−30</sub>, the backscattered coefficient (η) from 2 keV to 10 keV, η from 10 keV to 30 keV and Wp<sub>0</sub> was deduced. The S<sub>2−10</sub> calculated from this universal formula and the S<sub>2−10</sub> measured experimentally were compared, and we conclude that the formula presented in this paper is universal for S<sub>2−10</sub>.

      • SCIESCOPUSKCI등재
      • Directed Evolution of Beta-galactosidase from Escherichia coli into Beta-glucuronidase

        Xiong, Ai-Sheng,Peng, Ri-He,Zhuang, Jing,Liu, Jin-Ge,Xu, Fang,Cai, Bin,Guo, Zhao-Kui,Qiao, Yu-Shan,Chen, Jian-Min,Zhang, Zhen,Yao, Quan-Hong Korean Society for Biochemistry and Molecular Biol 2007 Journal of biochemistry and molecular biology Vol.40 No.3

        In vitro directed evolution through DNA shuffling is a powerful molecular tool for creation of new biological phenotypes. E. coli $\beta$-galactosidase and $\beta$-glucuronidase are widely used, and their biological function, catalytic mechanism, and molecular structures are well characterized. We applied an in vitro directed evolution strategy through DNA shuffling and obtained five mutants named YG6764, YG6768, YG6769, YG6770 and YG6771 after two rounds of DNA shuffling and screening, which exhibited more $\beta$-glucuronidase activity than wild-type $\beta$-galactosidase. These variants had mutations at fourteen nucleic acid sites, resulting in changes in ten amino acids: S193N, T266A, Q267R, V411A, D448G, G466A, L527I, M543I, Q626R and Q951R. We expressed and purified those mutant proteins. Compared to the wild-type protein, five mutant proteins exhibited high $\beta$-glucuronidase activity. The comparison of molecular models of the mutated and wildtype enzymes revealed the relationship between protein function and structural modification.

      • KCI등재

        Efficacy and safety of herbal medicine (Binafuxi granules) for the common cold with fever: A multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial

        Liu Xuemei,Min Jie,She Bin,Chen Yang,Li Jun,Huang Lei,Chen Ju,Luo Ai,Mei Yang,Li Ting,Wu Yanqing,Chen Daohong,Hongli Zhong,Liu Wei,Mao Bing,Jiang Hongli 한국한의학연구원 2023 Integrative Medicine Research Vol.12 No.3

        Background: Binafuxi granules are a traditional Uighur medicine (TUM) for treating the common cold with fever. However, high-quality clinical studies supporting its efficacy and safety are lacking. Methods: In this multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial, patients with common cold and fever were randomly assigned to a high-dose group, low-dose group, and placebo group in a 1:1:1 ratio. Outcomes were time to fever relief, time to fever clearance, proportion of afebrile patients, time to symptom disappearance, rate of symptom disappearance, effective rate, emergency drug usage and safety assessment. Results: A total of 235 patients were recruited. Of these, 234 were included in the full analysis set (FAS), and 217 were included in the per-protocol set (PPS). In the FAS analysis, the median time to fever relief was 6.00 h, 5.54 h and 10.65 h (P = 0.31) in the high-dose group, low-dose group and placebo group, respectively. The median time to fever clearance was 18.29 h, 20.08 h and 25.00 h (P = 0.0018), respectively, and the proportion of afebrile patients was 92.4%, 89.7% and 71.4% (P = 0.0002), respectively. There was a significant difference in the disappearance time and disappearance rate of all symptoms and of individual symptoms. No serious adverse events were found. Conclusions: Binafuxi granules can dose-dependently shorten the fever course and improve clinical symptoms in patients suffering from the common cold with fever.

      • KCI등재

        The GntR-Type Regulators GtrA and GtrB Affect Cell Growth and Nodulation of Sinorhizobium meliloti

        Yi Wang,Ai-Min Chen,Ai-Yuan Yu,Li Luo,Guan-Qiao Yu,Jia-Bi Zhu,Yan-Zhang Wang 한국미생물학회 2008 The journal of microbiology Vol.46 No.2

        GntR-type transcriptional regulators are involved in the regulation of various biological processes in bacteria, but little is known about their functions in Sinorhizobium meliloti. Here, we identified two GntR-type transcriptional regulator genes, gtrA and gtrB, from S. meliloti strain 1021. Both the gtrA1 mutant and the gtrB1 mutant had lower growth rates and maximal cell yields on rich and minimal media, as well as lower cell motility on swimming plates, than did the wild-type strain. Both mutants were also symbiotically deficient. Alfalfa plants inoculated with wild-type strain 1021 formed pink elongated nodules on primary roots. In contrast, the plants inoculated with the gtrA1 and gtrB1 mutants formed relatively smaller, round, light pink nodules mainly on lateral roots. During the first 3~4 weeks post-inoculation, the plants inoculated with the gtrA1 and gtrB1 mutants were apparently stunted, with lower levels of nitrogenase activity, but there was a remarkable increase in the number of nodules compared to those inoculated with the wild-type strain. Moreover, the gtrA1 and gtrB1 mutants not only showed delayed nodulation, but also showed markedly reduced nodulation competition. These results demonstrated that both GtrA and GtrB affect cell growth and effective symbiosis of S. meliloti. Our work provides new insight into the functions of GntR-like transcriptional regulators.

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