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외상성 뇌손상으로 인한 기억장애에 대한 가미활혈탕 치험 1례
허성규 ( Seong Kyu Heo ),김동건 ( Dong Gun Kim ),차윤엽 ( Yoon Yop Cha ),강희철 ( Hee Chol Kang ),박병철 ( Byong Cheol Park ),김진연 ( Jin Yon Kim ) 한방재활의학과학회 2006 한방재활의학과학회지 Vol.16 No.3
Objectives: The purpose of this study was to investigate the clinical application of oriental medical therapy to a patient with memory disturbance and disorientation caused by head trauma. Methods: This study was carried out on a patient who had a memory disturbance caused by head trauma, and whose condition was improved through herbal medication and acupuncture therapy. We estimated the effect of memory disturbance through MMSE-K(Korean Vision of Mini-Mental State Examination) and K-DRS(Korean-Dementia Rating Scale). Results and conclusions: Following the treatment the patient`s mental state was improved. The present results suggest that oriental medical therapy has the positive effects on a patient with memory disturbance.
회향(茴香) 추출물이 LPS를 처리한 Rat의 염증반응에 미치는 영향
허성규 ( Seong Kyu Heo ),이은 ( Eun Lee ),박원형 ( Won Hyung Park ),차윤엽 ( Yoon Yop Cha ) 한방재활의학과학회 2013 한방재활의학과학회지 Vol.23 No.2
Objectives :This study was performed to investigate the effects of Foeniculum Vulgare(FV) extract on the anti-inflammatory of lipopolysaccharide(LPS) exposed rats.Methods : We divided LPS exposed Sprague-Dawley rats into 4 groups. They were control group, feed with 100 mg/kg, 200 mg/kg, 300 mg/kg FV groups. They were administered for 6 weeks. We measured the concentration of plasma interleukin-1β(IL-1β), plasma interleukin-6(IL-6), plasma tumor necrosis factor-α(TNF-α), plasma interleukin-10(IL-10), the concentration of liver IL-1β, IL-6, TNF-α and IL-10.Results : 1. Plasma IL-1β, plasma IL-6 and plasma TNF-α concentration increased rapidly at 2hours after LPS injection and maintained high levels at 5hours after LPS injection. The concentration of these cytokines in the FV extract groups showed lower values than control group(P<0.05).2. The concentration of Plasma IL-10 in FV extract groups showed higher values than control group at all times(P<0.05). 3. The concentration of liver IL-1β and IL-6 in FV extract groups showed lower values than control group(P<0.05). The concentration of liver TNF-α in FV extract groups showed a tendency to decrease and that of liver IL-10 in FV extract groups showed a tendency to increase; however, these values showed no significantly different.Conclusions : In inflammatory response by LPS derivation, the FV gives positive effect.
교통사고 환자의 피부저항변이도에 관한 Pilot Study-Factor AA 중심으로-
허성규 ( Seong Kyu Heo ),차윤엽 ( Yun Yeop Cha ) 한방재활의학과학회 2008 한방재활의학과학회지 Vol.18 No.2
Objectives : The purpose of this study was to compare mean values of Factor AA on Skin Resistance Variability(SRV) of traffic accident patient group with those of non-traffic accident patient group(control group) by using 7-Zone-Diagnostic System. Methods : Two groups were selected from those who took the CP-6000A test in College of Oriental Medical Hospital of Sang-Ji University from March 2007 to November 2007. Two groups were control group(n=61) and traffic accident patient group(n=62). Mean values of Factor AA on Skin Resistance Variability(SRV) of two groups were compared. Results and Conclusions : The results suggest that traffic accident patient group and non-traffic accident patient group had problems in circulation but non-traffic accident patient group had more problems than traffic accident patient group, and that after oriental medical therapy, non-traffic accident patient group was more improved than traffic accident patient group. So, further studies will be needed.
정전가미이진탕(正傳加味二陳湯)이 과산화지질 급여 비만 쥐의 지질강하, 항산화효과 및 염증매개물질의 생산에 미치는 영향
허성규 ( Seong Kyu Heo ),박원형 ( Won Hyung Park ),차윤엽 ( Yun Yeop Cha ) 한방재활의학과학회 2013 한방재활의학과학회지 Vol.23 No.4
ObjectivesThe purpose of this study was investigating effects of Jengjengamiyijin-tang (zhengzhuanjiaweierchentang) (JGYT) on lowering lipid, antioxidation and production of in-flammatory mediators being used rats fed on high oxidized fat.MethodsWe divided fat Sprague-Dawley rats fed on high oxidized into 4 groups. Each of 8 rats was divided into a control group and experimental groups. We fed a control group of rats a basal diet and administered normal saline (100 mg/kg, 1 time/1 day) for 4 weeks. And We fed each experimental group of rats basal diet and administered an extract of JGYT extracts (100 mg/kg, 200 mg/kg, 300 mg/kg, 1 time/1 day) for 4 weeks. At the end of the experiment, the rats were sacrificed to determine their chemical composition. We measured lipid of plasma and liver, concentration of proinflammatory cytokines, anti-oxidative activity and plasma tumor necrosis factor-α (TNF-α), plasma interleukin-6 (IL-6), Apo-B, Apo-E and Leptin gene expression.Results1. Concentration of plasma FFA, LDL-cholesterol, plasma and liver total choles-terol showed a significant decrement in JGYT groups. However, concentration of plasma HDL-cholesterol showed a significant increment in JGYT groups. 2. Concentration of plas-ma and liver TG, TBARS showed a significant decrement in JGYT groups. However, con-centration of liver GSH-Px, SOD and CAT showed a significant increment in JGYT groups. 3. Plasma GPT activity and concentration of plasma IL-6, TNF-α, NO, Ceruloplasmin, α1- acid glycoprotein showed a significant decrement in JGYT groups. 4. In the analysis of RT-PCR, gene expression of Apo-B and Apo-E in the JGYT groups showed a low ex-pression than that of control group. However, the gene expression of leptin showed no dif-ference in all the treatment groups. 5. The ratio of leptin expression per β-actin expression showed no significant difference among all treatment groups. However, The ratio of Apo-B and Apo-E expression per β-actin expression showed a significant decrement in JGYT groups.ConclusionsAccording to this study, extract of JGYT showed a positive effect in low-ering lipid, antioxidation and control of inflammatory mediators production. (J Korean Med Rehab 2013;23(4):9-21)
수치료(水治療) 중 온천요법의 한의학적 문헌고찰 및 효능에 대한 연구
김동건,허성규,김유진,허영진,공인표,한석훈,조영호,공경환,정수현,차윤엽,Kim, Dong-Gun,Heo, Seong-Kyu,Kim, Eu-Gene,Heo, Young-Jin,Kong, In-Pyo,Han, Seok-Hun,Cho, Young-Ho,Kong, Kyung-Hwan,Jeong, Su-Hyeon,Cha, Yoon-Yeop 대한한방안이비인후피부과학회 2007 한방안이비인후피부과학회지 Vol.20 No.2
Objectives : The purpose of this study is to consider the definition, history, classification and clinical effect of balneotherapy. Methods : We researched oriental documents and recent sources of balneotherapy. Results and Conclusions : 1. Balneotherapy is medical cure method which uses physical chemistry effects of water. 2. Records of balneotherapy are seen in oriental documents such as Hwangjenaegyeong(黃帝內經), Sinnongbonchogyeong(神農本草經), Jaebyoungwonhuron(諸病源候論), Youmoonsachin(儒門事親), Bonchogangmok(本草綱目) and Donguibogam(東醫寶鑑) etc. 3. Spa can classify eleven types according to ingredient. The types were as following. Simple thermal spirng, Common salt spring, Sodium bicarbonated spring, Sulfate spring, Radioactive spring, Acid spring, Sulfur spring, Carbon dioxide spring, Iron spring, Alum spring & Sulfate-iron spring, Bicarbonatealkaline spring. 4. Physical, chemical and environmental effect of spa therapy have effectiveness on the chronic and we akness disease more than acute disease. And balneotherapy have more effectiveness on digestive disease, pulmonary disease, metabolic disease, circulatory disease, muscle skeletal disease and dermatologic disease than any other diseases.
차윤엽 ( Yun Yeop Cha ),허성규 ( Seong Kyu Heo ),김동건 ( Dong Gun Kim ) 한방비만학회 2006 한방비만학회지 Vol.6 No.2
The purpose of this study was to investigate the clinical application of Starvation and coffee enema and oriental medical therapy to a patient with obesity caused by overeating and lack of exercise. Methods : This study was carried out on a patient who had obesity caused by overeating and lack of exercise, and whose body weight was reduced through starvation, coffee enema and oriental medical therapy. After checked body weight, we analyzed effect of starvation, coffee enema and oriental medical therapy. Results and conclusions : Following the treatment the patient``s body weight was reduced. The present results suggest that starvation coffee enema and oriental medical therapy has positive effects on an obese patient
김유진 ( Eu Gene Kim ),차윤엽 ( Yun Yeop Cha ),김동건 ( Dong Gun Kim ),허성규 ( Seong Kyu Heo ),허영진 ( Young Jin Heo ),한석훈 ( Seok Hun Han ),공인표 ( In Pyo Kong ) 한방비만학회 2007 한방비만학회지 Vol.7 No.1
This study was performed to evaluate the effect of oriental medical treatment on aged female obese patient. Methods : We experienced an aged female obese patient. We applied herbal medication(Choweseuncheng-tang), electrolipolysis, auricular acupuncture to her from 26th, March. 2007 to 25th, May. 2007. And we examined the changes of her weight, body composition, body size, skin resistance variability, visual analogue scale of knee pain. Results : 1. Her weight decreased from 73.5kg to 71.1kg and body mass index(BMI) decreased from 29.46kg/m2 to 28.11kg/m2. 2. Body fat mass(BFM) decreased from 25.7kg to 21.6kg but body muscle mass(BMM) increased from 45.1kg to 46.7kg. 3. Waist-hip ratio(WHR) decreased from 0.96 to 0.92. 4. Basal metabolic rate(BMR) increased from 1,273kcal to 1,314kcal. 5. The circumference of upper extremity decreased 1.03cm and lower extremity decreased 1.30cm but the circumference of the muscle of upper extremity increased 0.41cm and lower extremity increased 0.63cm. 6. The circumference of chest and hip are decreased. In addition to the circumference and fat of abdomen are decreased. 7. The visual analogue scale of knee pain is improved. Conclusions : According to above results, oriental medical treatment could be used safety to aged obese patients without loss of fat free mass. The study is more required to aged obese patient from now on.