한방비만 치료와 정신요법

최승 ( Seung Choi ) 한방비만학회 2006 한방비만학회지 Vol.6 No.2

'스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

Based on the fact that obesity is a complicated disease, we must treat obesity in a holistic way, but psychological factors are usually neglected in the clinical field. Oriental Medicine is basically holistic and psychosomatic, however, there are very few psychotherapy approaches in Oriental Medical treatment. In this review Oriental Medicine psychotherapy is outlined and a new model for oriental psychotherapy for the treatment of obesity is introduced. This program has a multi dimensional approach that includes behavioral, cognitive and spiritual components. The behavioral component relates to the discipline of diet and exercise. The cognitive aspect focuses on the mind. The third and possibly the most important component deals with one`s spirit and awareness of their true self. This program is called "Yangsung" which means "Finding and raising one`s true self."

마황이 포함된 한방비만 처방과 Lorcaserin 병용 투여 후 호전된 비만 환자 치험 2예

김민지,최한석,김호준 한방비만학회 2019 한방비만학회지 Vol.19 No.1

Although there has been many studies about the co-administration of herb formula and western medicine, there is none about obesity. The aim of this study was to report the effects of co-administration of herb formula containing ephedra sinica and lorcaserin on two obese patients for about 2~4 months. During the treatment, we checked body weight and body composition, and collected blood samples to evaluate liver, kidney, thyroid function and lipid profile. This treatment not only decreased body weight but also improved body composition and lipid profile in both patients. There was no hepatic or renal toxicity, nor any serious side effects of treatment. This study demonstrated that co-administration of herb formula containing ephedra sinica and lorcaserin is a safe and effective therapy to lose weight and improve metabolic parameters for obese patients. Further large-scale clinical trials are needed to evaluate the anti-obesity effect of the combination of herbal and western medicines.

CARE (CAse REport) 지침에 의한 한방비만학회지 증례 논문에 대한 보고의 질 평가: 2013년~2018년 증례보고를 중심으로

박경무,최성열,이주아,송윤경 한방비만학회 2018 한방비만학회지 Vol.18 No.2

'스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

Objectives: The purpose of this study is to evaluate the quality of case reports of the Journal of Korean Medicine for Obesity Research by the Case Report (CARE) guidelines. Methods: Case reports published in the Journal of Korean Medicine for Obesity Research from January 2013 to July 2018 were searched from Oriental Medicine Advanced Searching Integrated System (OASIS). We assessed the quality of reporting based on CARE guidelines. Results: A total of 8 case reports were finally included for the assessment. There was a deviation in the sub-item reporting rate by a maximum 75% and a minimum 57.14% in case reports. The 10 sub-items mentioned below, such as 'Timeline', 'Diagnostic challenges', 'Diagnostic reasoning including other diagnoses considered', 'Prognostic characteristics', 'Changes in intervention', 'Important follow-up diagnostic evaluations and other test results', 'Intervention adherence and tolerability', 'Adverse and unanticipated events', 'Patient perspective' and 'Informed consent' were reported below 30%. Conclusions: Efforts to diversify the subject of the case study and to apply appropriate reporting guidelines are needed to improve the quality of the case report contributed to the Journal of Korean Medicine for Obesity Research.

최근 10년간 한방비만학회지의 연구동향 분석: 2010-2019년 한방비만학회지 게재논문을 중심으로

박서현,송윤경 한방비만학회 2020 한방비만학회지 Vol.20 No.2

Objectives: This study performed to identify trends in research published in the Journal of Korean Medicine for Obesity Research during last one decade. Methods: All of the articles in the Journal of Korean Medicine for Obesity Research published from 2010 to 2019 were collected. Search were conducted through “http://jkomor.org.” Collected articles were classified into year and type of publication. Additional data including study design, study topics, characteristics of participants and treatment, outcomes was extracted from full text of each study. Results: Total 135 articles were analyzed. The number of studies were increasing after 2015. According to classification by type of study, percentage of clinical study took 27%, preclinical study took 37%, literary study took 21%, and case report took 15%. The number of studies were grown and study topics have been diversified. However for the growth of quality, concern for subjects, study design, quality assessment according to research guidelines and ethical consideration is needed. Conclusions: The number of studies and issues each study focused on have been increasing. To improve the quality of studies, further studies should be followed.

한약추출물을 함유한 식사대용식이가 체중감량과 초저열량식이의 부작용에 미치는 영향

최승 ( Seung Choi ), 최형석 ( Hyung Suk Choi ), 김지영 ( Ji Young Kim ), 장유경 ( Yu Gyung Jang ), 김상연 ( Sang Yeon Kim ), 박미현 ( Mi Hyun Park ), 홍성길 ( Seong Gil Hong ), 황성주 ( Seong Ju Hwang ) 한방비만학회 2004 한방비만학회지 Vol.4 No.1

'스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

Background : The VLCD that supplies only 400-800kcal meal per day has a lot of problems and can severely harm the health. Certain herbs are known tothe side-effects such as weakness, skin dehydration, and dizziness. If VLCD with meal-replacement containing these hearbs can effectively minimize the side-effects, itmake weight management easier and reduce any possible dangerthe health. Objectives : This prospective, double-blinded study is intended to compare the severity of symptoms induced by VLCD and weight loss between the case group supplied with meal-replacementherbal extracts(n=29) and controlled groupsupplied with meal-replacement not containing herbal extracts(n=29). Thiswaswith 52 volunteers for 4 weeks. The measurements of this experiment were as follows: symptoms caused by patients` subjective judgments, the result of blood test illustratingerol level, total protein etc., and changes in overall weight, fat mass and lean body mass. Result : we concluded that there are no significant differences in weight change between case group and controlled group, and that the total protein at the end of trial was significantly higher in case group than in controlled group, and triglyceride level at the end of trial was lower in case group than in controlled group. As expected, the side-effects such as hair loss and dehydration in skin are also lessin case group than in controlled group.

비만 치료 한약 무작위 대조 임상시험에서의 음식 섭취량과 운동량 실태분석

김두희 ( Doo Hee Kim ), 신우석 ( Woo Suk Shin ), 박원형 ( Won Hyung Park ), 차윤엽 ( Yun Yeop Cha ), 송윤경 ( Yun Kyung Song ), 안민윤 ( Min Youn Ahn ), 고성규 ( Seong Gyu Ko ) 한방비만학회 2013 한방비만학회지 Vol.13 No.2

'스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

The objective of this study was to analyse the methods being used to control food intake and physical activity in RCTs of human obesity. Methods: A total of 21 randomized controlled trials (RCTs) were investigated. Nine of which were domestic studies from "http://oasis.kiom.re.kr" and the other of which were foreign studies from systematic reviews of RCTs on herbal medicine for treatment of human obesity. Results: According to domestic studies, "low calorie diet" were recommended in five cases of the domestic studies , "maintain current dietary habit" were recommended in two and no information on diet was two. Considering the seven cases where the information on diet was available, patients`` food intake were checked at every visit in six cases. Only two cases among the six had been dropped owing to the violation of dietary habit by patients. Exercises were prohibited in two cases, "maintain current level of phisical activity" were recommended in three cases and, from the rest, no information was available. The level of physical activity were not strictly controlled by any means hence no drop out. According to foreign studies, "low calorie diet" were recommended in two cases, "very low calorie diet (less than 700 kcal/day)" in one case, "maintain current dietary habit" in two cases, "do not eat fat" in two cases and no information was available in the rest five cases. Exercises which concerns spending about 300 kcal/day was recommended in one case, "moderate exercise" were recommended in three cases, "maintain current level of physical activity" were recommended in three cases and no information available in the rest five cases. Conclusions: In order to improve the accuracy of RCT, for the dietary side, researchers should record patient food intake at every visit by means of 24-hour dietary recall methods. This can be supplemented by multiple choice survey that are designed to help patients to diagnose themselves more accurately leading to less bias. For the exercise side, it is highly recommended to confine the exercises to walking only so as to quantify the amount of physical activity more easily by using pedometer.

혈액검사 결과를 바탕으로 살펴본 노인 비만 특성 고찰

신우석,고찬희,최정은,박원형,차윤엽,이상욱 한방비만학회 2013 한방비만학회지 Vol.2 No.2

Objectives: The purpose of this study was to investigate the characteristics in elderly populationwith obesity by analyzing their blood test. Methods: Included 130 subjects of aged 60 or older went through body composition test, andblood test. We divided them into obesity group and normal group based on body mass index (BMI)results, and then the blood test results were compared between the groups. Results: Forty out of 130 subjects had BMI of 25 or more. Two groups showed significantdifference in bilirubin total, alanine aminotransferase (ALT), cholesterol total, triglyceride, highdensity lipoprotein (HDL), red blood cell (RBC), hematocrite, mean corpuscular hemoglobinconcentration, and platelet. All but HDL levels showed significantly higher results in obesity groupthan normal group. When compared with BMI, blood urea nitrogen, creatinine, ALT, cholesteroltotal, triglyceride, white blood cell (WBC), and RBC had significant positive correlations. Amongthose, cholesterol total, triglyceride, WBC, and RBC showed significant difference between twogroups, with correlation to BMI. Especially, the average of triglyceride was higher than normallimit in obesity group, whereas it was lower than normal limit in normal group. Conclusions: Triglyceride, cholesterol total, WBC, and RBC are highly related to obese elderly inthis study. Old people with obesity need to be careful of cardiovascular and metabolic disease thatcan be caused by these factors.

C2C12 골격근 세포에서 백출의 분화 조절 효능

송미영 ( Mi Young Song ) 한방비만학회 2015 한방비만학회지 Vol.15 No.1

'스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

Objective: Skeletal muscle is a crucial tissue from the perspectives of mitochondrial dysfunction and insulin resistance, it is formed by myogenesis which is dynamic multistep process to be myotubes. The authors could found that root of Atractylodes macrocephala Koidzumi (Atractylodis Rhizoma Alba, ARA) enhanced glucose and lipid metabolism in C2C12 myotubes via mitochondrial regulation. However its action in myogenesis process is not known. The aim of this work was the study of ARA on proliferation, differentiation and hypertrophy in C2C12 cells. Methods: To study proliferation phase, cells were incubated in growth medium with or without ARA (0.2 or 1.0 mg/ml) for 24 hours. To examine differentiation, at 70% confluence, cells were transferred in differentiation medium both with/without ARA (0.2 or 1.0 mg/ml) for 96 hours. And after 72 hours of differentiation, cells were treated with or without ARA (0.2 or 1.0 mg/ml) for 24hours, the genesis of hypertrophy in myotubes were analyzed. Results: In proliferation phase, ARA could make difference in morphologic examination. In differentiation phase, it also made morphologic difference furthermore ARA (1.0 mg/ml) increased mRNA expressions of Myogenic regulatory factors and muscle-specific proteins synthesis. In late differentiation, ARA induced hypertrophic morphological changes in neo-formed myotubes. Conclusions: ARA might control cell cycle promoting myogenesis and hypertrophy in C2C12 cells.

식이장애

이재성 ( Jae Sung Lee ) 한방비만학회 2002 한방비만학회지 Vol.2 No.1

'스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

식이장애란 체형과 체중에 대해 과도한 집착과 왜곡된 인지를 가지면서 비정상적인 식사행동을 반복하고 그에 따른 신체적, 심리적 부작용을 나타내는 장애를 말하며, 대표적으로 신경성 식욕부진증 및 신경성 폭식증이 있으며, 그 외 폭식장애를 비롯한 달리 분류되지 않은 식이장애가 있다. 서구문화의 급속한 유입으로 인하여 1990년대 이후 우리나라에서도 식이장애의 발병율이 점차 증가하는 추세에 있으며 특히 청소년과 조기 성년기 여성에게서 문제가 되고 있다. 비만 클리닉에 체중감량을 원해 내원하는 환자들은 식이장애에 대한 고위험군일 가능성이 있으며, 체중감량을 위한 과도한 식사제한은 자칫 식이장애를 유발할 수 있으므로 비만클리닉 임상의들이 식이장애에 대한 이해를 갖고 적절한 식이요법을 지도하는 것이 필요하다고 생각된다. Eating disorders are psychiatric disorders characterized by abnormal eating patterns and cognitive distortions related to food, weight and shape, which is in turn result in adverse effects on nutrition status, medical complications, and impaired health status and function. The American Psychiatric Association`s DSM-Ⅳ-TR offers two diagnoses to describe disordered eating: anorexia nervosa and bulimia nervosa. A third category, eating disorder not otherwise specified(EDNOS) include binge eating disorder. The prevalence of eating disorder has greatly increased among adolescence and young adults since 1990`s when rapid import of western culture took place. It is likely that patients who ask for weight loss are at high risk of having eating disorder. Severe dietary restriction for weight loss may cause eating disorder. Therefore it is recomendable for doctors to have appropriate understanding and guidelines of eating disorder to help their patients.

가미 태음조위탕과 저열량 식이를 병행한 체중 감량 프로그램에서 발생한 이상 반응 분석

윤나라(Na-Ra Yoon), 유영재(Young-Jae Yoo), 김민지(Min-ji Kim), 김서영(Seo-Young Kim), 임영우(Young-Woo Lim), 임형호(Hyung Ho Lim), 박영배(Young-Bae Park) 한방비만학회 2018 한방비만학회지 Vol.18 No.1

'스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

Objectives: The objective of this study was to assess the safety of Gamitaeeumjowee-tang by analyzing adverse events in weight loss program in combination with Gamitaeeumjoweetang and low-calorie diet. Methods: A retrospective review of adverse events in weight loss program in combination with Gamitaeeumjowee-tang and low-calorie diet from the electronic medical chart (n=124) between June 2015 and December 2016 was conducted. Three Korean Medicine Doctors (KMDs) reviewed adverse events for two times, during week 2 to 4 and at week 10, after starting weight loss program. Adverse events were evaluated in terms of causality, severity and system-organ classes. Also, agreement among the three KMDs was made through further discussion in case of disagreement after independent review. Results: The overall rate of adverse events was 37.1% during week 2 to 4 and 16.9% at week 10. For causality of adverse events using the World Health Organization-Uppsala Monitoring Centre causality categories, 52.2% were evaluated possible at week 2-4 and 57.1% were evaluated unlikely at week 10. All symptoms were evaluated as mild by LDS scale. Nausea (15, 12.1%) was the most frequent adverse event at week 2-4 and dizziness (6, 4.8%) was the most common at week 10. Conclusions: Adverse events decreased over time. There were no serious adverse events and none of the subjects were dropped due to adverse events. Continuous study is needed to prove the safety of Gamitaeeumjowee-tang for treating obesity.