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Voice is made by systemic interaction of respiration, vocalization, articulation and resonation. There is no existing multi-channel voice analysis system to assess voice and respiration simultaneously. The most existing systems consist of. vocal fold vibration measurement such as stroboscopy, EGG (electroglottography) or laryngeal electromyography and voice analysis system. Since respiration has close relationship with voice simultaneous analysis of both vocal cord vibration and respiration are essential. In this study, a four channel integrated system are developed for acoustic analysis through microphone, vocal fold vibratory analysis using EGG, and respiratory analysis using two channel RIP (respiratory inductive plethysmography).
정세화 ( Se Hwa Jung ), 백상현 ( Sang Hyun Baik ), 노현기 ( Hyun Ki Roh ), 강나라 ( Na Ra Kang ), 임재중 ( Jae Jung Im ), 이병하 ( Byung Ha Lee ), 전재윤 ( Jae Yoon Jeon ), 황경균 ( Kyung Gyun Hwnag ), 심광섭 ( Kwang Sup Shim ), 박창주 ( C) 大韓顎顔面成形再建外科學會 2009 Maxillofacial Plastic Reconstructive Surgery Vol.31 No.5
전재윤,정세화,이병하,임재중,황경균,심광섭,박창주,Jeon,,Jae-Yun,Jung,,Se-Hwa,Lee,,Byung-Ha,Im,,Jae-Jung,Hwang,,Kyung-Gyun,Shim,,Kwang-Sup,Park,,Chang-Joo 대한치과마취과학회 2009 Journal of Dental Anesthesia and Pain Medicine Vol.9 No.2
Midazolam, one of the most common benzodiazepine derivatives, is widely used in intravenous sedation for dental treatment without severe complications. However, paradoxical reactions to midazolam, including patient's unanticipated restlessness, agitation, hostility, and rage, have been frequently reported since the introduction of benzodiazepine. During outpatient intravenous sedation using midazolam for dental treatment, we experienced a paradoxical reaction to midazolam in a 28-year-old female patient. With a thorough review of the literature, the management of this complication and its various etiologies were discussed.
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Purpose : Cyclosporine A (CsA) is a versatile immunosuppresive agent used to prevent graft rejection syndrome and treat autoimmune disease. One of the major side effects associated with CsA is the abnormal gingival hyperplasia. The purpose of this study was to investigate the relationship between the mRNA expression of the MMP-1, TIMP-1, and TGF-β1 and the concentration of CsA in cultured human gingival keratinocytes. Materials & Methods : Gingival keratocytes were obtained from gingival tissues of 4 healthy donors. The cultured gingival keratocytes were incubated with increasing concentrations of CsA (0-2000 ng/ml) for 24 hours and the expression of MMP-1, TIMP-1, and TGF-β1 were determined by reverse transcription-polymerase chain reaction (RT-PCR). Results : The expressions of MMP-1 and TGF-β1 were not significantly different according to the concentrations of CsA. The expression of TIMP-1 was significantly increased at the CsA concentration of 500 ng/ml. Conclusion : We concluded that the gingival hyperplasia induced by CsA was more related with TIMP-1 than MMP-1 or TGF-β1 on gingival collagen metabolism in patients treated with CsA.
서영준 ( Young Jun Seo ), 정성우 ( Sung Woo Jung ), 강학수 ( Hag Soo Kang ), 임재중 ( Jae Jung Im ), 허영성 ( Young Sung Huh ), 우순섭 ( Soon Seop Woo ), 심광섭 ( Kwang Sup Shim ), 황경균 ( Kyung Gyun Hwang ) 대한악안면성형재건외과학회 2005 Maxillofacial Plastic Reconstructive Surgery Vol.27 No.4
Background : P300 component of the long latency auditory evoked potentials(LLAEPs) provides information on conscious and cortical funtion. The P300 wave occures only for stimuli that somehow capture the patients attention. Therefore LLAEPs implys a degree of cognitive processing. We studied sedation scale and P300 wave to determine if LLAEPs could be utilized as electrophysiologic predictors of sedation. Methods : The P300 component of LLAEPs from vertex was recorded from 10 ASA physical status I and II patients undergoing elective surgery while they listened via headphones to a series of clicks which were interrupted unpredictably by a tone burst(2 KHz) before and after diazepam 0.04 mg/kg and 0.08 mg/kg IV. The patients were asked to concentrate on the clicks and to press a button whenever they detected a 2 KHz tone. And sedation scale also was measured. Results : Amplitude of P300 was decreased and latency of P300 was increased in a dose-dependent manner with IV diazepam. Amplitude was greatest and latency was shortest in awake. And sedation scale also was increased according to increased IV diazepam adminstration. Conclusions : Both amplitude and latency may be highly related to the sedation scale with progressively increasing dose of diazepam. Therefore we conclude that P300 component of LLAEPs can be utilized as an electrophysiologic predictor of awareness and sedation. (Korean J Anesthesiol 1997; 33: 248∼253)