肺 組織에서 胡桃 抽出液이 酸化性 細胞 損傷의 防禦棋戰에 미치는 影響

李佑憲,徐雲敎,鄭智天 동국대학교 한의학연구소 1997 東國韓醫學硏究所論文集 Vol.6 No.1

胡桃는 補陽藥으로써 下焦를 溫補하고 元氣를 攝納하며 潤肺腎하는 效能이 있어 오래된 虛寒咳嗽, 喘息의 治療에 사용되어 왔는데 肺 組織內에서 酸索遊離基들에 依한 細胞 損傷의 防止 여부를 알아보기 爲하여 酸化劑인 t-butylhydroperoxide(t-BHP)와 H₂O₂로써 細胞 損傷을 유발한 후 胡桃 抽出液의 抗酸化 效果 및 抗酸化 酵素의 活性에 미치는 影響과 酸素遊離基에 對한 직접 消去效果를 調査하였다. 이 결과 胡桃는 肺 組織에서 脂質의 過酸化를 抑制함으로 oxidant에 依한 肺浮腫 誘發을 防止할 수 있음을 보여주었고 細胞內 glutathione의 濃度 및 抗酸化 酵素 中 catalase 와 superoxide dismutase 活性에는 變化를 유발하지 못하였으나 glutathione peroxidase의 活性을 有意하게 增加시켰으며, superoxide radical과 hydroxyl의 生成을 減少시켰다. 따라서, 肺 組織에서 酸化性 細胞 損傷에 對한 胡桃의 保護 效果는 부분적으로 細胞內 抗酸化 酵素의 活性 增加와 酸素遊離基들을 직접 消去시키는 作用에 起因하는 것으로 사료된다. This study was undertaken to determine whether Juglandis Semen extraction(JS) has a protective effect against the lung cell injury caused by oxidants, t-butylhydroperoxide(t-BHP) and H₂O₂in rabbit lung slices. JS significantly prevented an increase in water content indured by t-BHP. Similarly, JS slgnificantly prevented the lipid peroxidation induced by t-BHP. Cellular concentration of glutathione, and the activities of catalbase and superoxide dismutase were significantly not altered by 5% JS. However, JS at 5% concentration significantly increased the glutathione peroxidase activity in oxidant-treated and control tissues. JS decreased directly the production of superxide or hydroxyl radical. These results indicate that JS prevents the cell injury and lipid peroxidation induced by oxidants in the lung. Such an antioxidant effort is attributed to enhancement of major endogenous antioxidant defence systems such as glutathione peroxidase and direct inhibition of oxygen free radical production.

복귀돌연변이시험을 이용한 이온화에너지 처리 우유 및 아이스크림의 유전독성학적 평가

유지숙, 한선경, 신명수, 구본철, 최지현, 이주운, 조철훈, 함준상, 이완규 충북대학교 동물의학연구소 2008 Journal of Biomedical and Translational Research Vol.9 No.1

본문참고

TSC 합성보의 제작방법에 따른 구조적 거동에 관한 실험적 연구

이지운,김도훈,김성배,이창남,김상섭,김규석 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

Composite action can be achieved by providing shear connectors between steel top flange and concrete topping. Composite sections have larger stiffness than the summation of the individual stiffness of slab and beam, therefore, can carry larger load or similar loads with appreciably smaller deflection and are less prone to transient vibration. T-type Steel Composite beam(TSC-beam) is developed and tested. To make the part of steel beam, we used the way of welding two steel plates as well as the way of folding one steel plate.

T형 합성보의 구조거동에 대한 실험적 연구

이지운,김성배,김상모,이창남,김상섭 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2(구조계)

Composite action can be achieved by providing shear connectors between steel top flange and concrete topping. Composite sections have larger stiffness than the summation of the individual stiffness of slab and beam, therefore, can carry larger load or similar loads with appreciably smaller deflection and are less prone to transient vibration. T-type Steel Composite beam(TSC-beam) is developed and tested. The test results of TSC beam are compared with the theoretical results based on composite actions.

임베디드 리눅스 기반의 영상처리기법에 관한 연구

원지운,정원교,홍원기,이용두 대구대학교 정보통신연구소 2004 情報通信硏究 Vol.3 No.1

현재 embedded system에서 많은 기업체들이 리눅스를 채용하고 있고, 우리 생활에서 쓰이는 각종 전자기기, 정보가전, 제어장치 등에 적용되고 있다. 최근 멀티미디어 처리와 같은 점차 복잡한 기능이 요구되면서 임베디드 운영체제를 사용하기 시작하였고, 이러한 운영체제로 리눅스가 주목받게 되었다. 이는 가격 경쟁력뿐만 아니라 각 H/W에 따라 운영체제와 응용프로그램을 다양하게 변화시킬 수 있다. 본 논문에서는 CCD 카메라로부터 영상을 입력받아 압축하여 LCD 모니터에 출력하기 위한 임베디드 시스템 기반의 영상처리에 관해 기술한다. Recently, many industries adopts linux as an operating system for embedded system, which is commonly used in our life as the type of electronic machinery, electric home appliances and so on. The embedded operating system is getting more complex as lots of features such as multimedia are required. The operating system should be adjusted to the hard ware and software in order to satisfy a competitive price. In this paper, a operating system is discussed in order to compress the images form the CCD camera and then spread the LCD.

유동상 생물막법을 적용한 BNR공법에서의 인제거 영향인자

박운지,김동욱,이찬기 江原大學校 産業技術硏究所 2006 産業技術硏究 Vol.26 No.B

In this study, the use of MBBR(moving bed biofilm reactor) process for Phosphorus Removal efficiency depending on seasons and the factors affecting phosphorus removal efficiency in the process is evaluated. As a result of experiment, T-P removal efficiency has its highest value in winter, (80.8%). and T-P removal efficiency has its lowest value in autumn, (49%). Optimum SRT for Phosphorus Revomal revealed is about 8.8 days and process performs more efficiently as the temperature decreases. It is accepted that nitrate to anaerobic zone is affecting the Phosphorus removal process. With increasing the organic loading rate, Phosphorus removal efficiency also increases. Also, an experiment has been conducted to find out the highest efficiency according to Media existence and it has revealed that Media addition provides better phosphate removal.

스테인레스 강(304) 표면에 형성된 부동상태 피막의 조성

안윤선,이경철,지홍근 성균관대학교 기초과학연구소 1989 論文集 Vol.40 No.2

스테인레스 강(304) 표면의 부동상태 성질을 규명하기 위해서 "as received" 상태 표면과 CrO_3/H_2SO_4 용액으로 활성화시킨 표면을 Ar이온으로 깍아 내려가면서 ESCA로 표면원소들의 조성 및 산화상태를 측정하였다. 지금까지의 많은 보고와는 달리 "as received" 상태에서는 O₂분자가 표면층에 깊숙히 침투되어 있음을 발견하였다. 이것은 부동상태 산화피막의 형성과정이 크롬과 철의 상대적 확산 속도차에 의해서도 다르지만, bulk 속으로 산소가 확산되어 들어가는 정도에도 의존함을 나타내는 것이다. In order to study the passive state of stainless steel(304, austenite), the depth profile of surface composition as well as its oxidation state has been investigated by means of X-ray photoelectron spectroscopy. The study has been carried both on a "as received" state surface and surface activated in CrO_3/H_2SO_4 solution. Its has been found contrary to the previous works that a considerable molecular oxygen are penetrated deep into the oxide layer. This is an indication that the passive state oxide- film formation depends not only on the relative diffusion rates of chromium and iron, but also on the diffusion rate of oxygen into the hulk.

강우 시 도시 하천으로의 비점오염원 유출특성

박운지,김동욱,안종화,이찬기 江原大學校 産業技術硏究所 2007 産業技術硏究 Vol.27 No.B

We studied runoff characteristics of combined sewer overflows in a city while it was raining. The event mean concentration (EMC) of biochemical oxygen demand (BOD), chemical oxygen demand (COD_(cr)), suspended solids (SS), total nitrogen (TN), and total phosphorus (TP) in one of the combined sewer sites in Chuncheon was 63.5-211.6 mg/L, 114.9-523.8 mg/L, 70.3-436.4 mg/L, 6.4-33.0 mg/L, and 1.09-6.81 mg/L, respectively, In another combined sewer, the EMC of BOD, COD, SS, TN, and TP was 42.1-131.4 mg/L, 107.7-256.5 mg/L, 33.7-221.1 mg/L, 7.9-26.4 mg/L, and 1.16-3.91 mg/L, respectively. The ratio of the cumulative pollutant mass and the cumulative discharged volume determined using all parameters (BOD, COD_(cr), SS, TN, and TP was over 1.0, which shows the first flush effect. Relationships between flow and loadings of BOD, C0D_(cr), SS, TN, and TP were 0.90, 0.89, 0.88, 0.89, 0.92, respectively. Although the size of two areas was almost same, Pollutant concentration and loading were different because of the amount of rainfall, rainfall intensity and basin area.

프로스타글란딘 E₁에칠에스테르의 외용 리오겔 제제 설계

양성운,이진교,이지은,김희규,박혜숙,김종석,최한곤,용철순,최영욱 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.2

External lyogels containing prostaglandin E₁ethyl ester(PGE₁-EE), a produrg of prostaglandin E₁(PGE₁) as a therapeutic agent for erectile dysfunction, were formulated to overcome the aqueous instability and enhance the percutaneous absorption. Lyogels of PGE₁-EE were prepared with ethanol (EtOH)/proplyene glycol (PG) cosolvent system as a vehicle, cineol as an enhancer, and hydroxypropylcellusose as a gelling agent. In vitro percutaneous absorption studies were performed to determine the rate of PGE₁ absorption through rat or hairless mouse skin. The permeability of PGE₁-EE lyogel with enhancer was 16-fold greater than that of lyogel without enhancer. Cosolvent produced 9-fold increase in percutaneous absorption. Pharmacodynamic effects of lyogels were evaluated in mature male cats in terms of intracavernosal pressure (ICP). Lyogles containing 0.01% of PGE₁-EE showed higher ICP compared to intraurethral preparation of PGE₁(1%) and enhancer-free control lyogel. The shelf-life (t_(10%) of lyogel at refrigerated condition (4℃) was calculated as 928 days, which is 4.2 times longer than that of control hydrogel. As a result, PGE₁-EE was formulated successfully to a lyogel system with a selective enhancer and cosolvent system for the topical delivery of PGE₁.

급성 신우신염이 선행된 Escherichia coli 농흉 1예

차치운,조준형,김미진,오윤정,연재우,이성규,오미정,채지영,김수연 대한감염학회 2009 감염과 화학요법 Vol.41 No.5

We experienced a case of acute pyelonephritis which progressed to Escherichia coli bacteremia and later complicated by empyema in a 65-year-old female. She was successfully treated with intravenous antibiotic therapy and percutaneous drainage of empyema.