한국 정신장애의 역학 조사 연구[I] : 각 정신장애의 유병률

조맹제,함봉진,김장규,박강규,정은기,서동우,김선욱,조성진,이준영,홍진표,최용성,박종익,이동우,이기철,배재남,신정호,정인원,박종한,배안,이충경 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4

Objectives : This study aims to estimate the prevalence of the DSM-IV psychiatric disorders in Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI). Methods : Subjects were selected by taking multi-stage, cluster samples of 7,867 adult household residents, 18 to 64 years of age, in ten catchment areas. Total 78 trained interviewers administered the K-CIDI to the selected respondents, from June 1 to November30,2001. Results : Total 6,275 respondents completed the interview. Some 33.5% of respondents reported at least one lifetime disorder, 20.6% reported at least one-year disorder, and 16.7% reported at least one-month disorder. The most common lifetime disorders were alcohol abuse/dependence (17.24%), nicotine dependence/withdrawal (11.19%), specific phobia (5.16%), and major de-pressive disorder (4.25%). The lifetime prevalence of substance abuse/dependence (0.25%) and schizophrenia (0.16%) was very low. Nicotine and alcohol use disorder showed very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among female than male. Conclusion : The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in distributions of psychiatric disorders across the areas and times were observed.

대상포진의 임상적 연구

박장규,김윤성,구자경 충남대학교 의과대학 지역사회의학연구소 1985 충남의대잡지 Vol.12 No.2

The authors analized 78 patients with herpes zoster treated at Department of Dermatology, Chungnam National University Hospital from 1982 to 1985 to find out the epidemiology and clinical course. The results were as follows: 1. The annual prevalence rate of herpes zoster ranged 1.5% to 2.0%(mean 1.8%) and did not increase during 8 years from 1977 to 1984. 2. There was no sexual difference. 3. Herpes zoster was seen most frequently in the 50-59 year age group (24.4%), in July in a year (16.7%) and during summer(34.6%). 4. The dermatomic involvement of herpes zoster was most common on thoracic nerve(48.7%), and others were trigerminal nerve (28.2%), cervical nerve (14.1%), lumbar nerve(6.4%) and sacral nerve(2.6%) in order. 5. The interval of onset of subjective symptoms and vesicle appearance was 3.9 days in average. The mean duration of treatment was 13.8 days. There was a tendency that both interval and duration increased with increasing age. 6. The most common complication of herpes zoster was postherpetic neuralgia (6.4%) and others were keratoconjunctivitis(2.5%), herpes zoster with aberrant vesicles (2.5%) and recurrent herpes zoster (1.3%).

患者에서 分離된 포도구균이 分泌하는 β-lactamase의 性狀에 關한 硏究

朴粧緖,朴鼎圭,崔大卿 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.1

This study was carried out for the purpose of investigating the β-lactamase producing rates using acidimetric assay and disc method. Also, the author evaluated the drug resistance of ,β-lactamase producing staphylocci isolated from 34 patients in Chungnam National University Hospital and 25 medical students in Chungnam National University by antibiotic susceptibility test. The author sconducted the survey from January to June 1985. The results obtained were as follows: 1. Out of the 34 specimens from patients, Staphylococcus aureus isolated from pus and throat were 58.8% and 17.6%, respectively. 2. The β-lactamase producing rates of staphylococci isolated from patients and control groups using acidimetric assay after 1 year were 88. 2% and 84. 0%, respectively. 3. In the disc method and acidimetric assay, the (β-lactamase producing rates of staphylococci isolated from patients and control groups were 91.2%, 88.2% and 88.0%, 84. 0%, respectively. 4. The rates of resistance for penicillin among p-lactamase producing strains of staphylococci isolated from patients and control groups were 91.2% and 60.0%, respectively. 5. Out of the β-lactamase producing staphylococci isolated from patients and control groups, 88. 2% and 56. 0% were resistant to penicillin but sensitive to cephalothin.

一部 樂器의 演奏音에 의한 暴露歷이 聽力에 미치는 影響

박종안,장봉기,이종화,안규동,이영세 순천향대학교 산업의학연구소 1997 순천향산업의학 Vol.3 No.1

This study was carried out to evaluate the effect of playing musical instruments on hearing threshold level from May to October, in 1997. Pure tone audiometric tests was provided to musical instruments playing group of total 117 subjects(Samullnori; 35, military band; 25, symphony orchestra; 46, piano; 11), and reference group of total 7,477 subjects, selected after excluding workers with history of ear disease, of ototoxic drug administration, of noise induced hearing loss at workplace in Pohang industrial area. In addition, noise exposure levels of musical instrument players were assessed by noise dosimetry(exchange rate; 5dB, threshold level; 80dB, criterion level; 90dB), and produced age-adjusted hearing threshold level(=hearing threshold level of musical instrument player - hearing threshold level in same age of normal population group). The age-adjusted hearing threshold levels were analyzed by musician's career. The results were as follows; 1. The hearing threshold level of reference group was revealed more increased as within 4.98dB to 6.89dB at 1 KHz and within 5.26dB to 14.46dB at 4 KHz by ages than "the Standard of Age-adjusted Hearing Loss by Frequency(OSHA)" used for special health examination in the Ministry of Labour. 2. Equivalent continuous sound exposure level (Leq) by the group of instrumentalist was as following; within 104.95 to 112.62dB in samullnori, the highest, within 100.18 to 103.49dB in military band, within 77.00 to 82.74dB in symphony orchestra and 81.54dB in piano, the lowest. Playing maximum sound level by each musical instrument was as following; 122.8dB in Kkwaenggwari, the highest, 122.7dB in Changgo, 121.8dB in Alto saxophone, 115.5dB in Trumpet, 119.2dB in Horn, 112.8dB in Pungmul Buk and Ching, 112.5dB in Clarinet. 3. Average age-adjusted hearing threshold levels of instrumentalists were -0.65±6.38dB in left ear, -0.92±6.59dB in right ear at 1 KHz, and -1.14±12.88dB in left ear, -1.53±12.77dB at 4 KHz, which were better than normal, but the average age-adjusted hearing threshold levels of Samullnori players were 1.23±5.22dB in left ear, 1.94±6.91dB in right ear at 1KHz, and 8.40±15.75dB in left ear. 7.13±14.97dB in right ear at 4KHz, which were worse than normal. 4. Hearing threshold level in Samullnori players was increased with their career at 4 KHz, especially it increased rapidly when the musicians had played over 10years. It showed that there was a significant relationship between hearing threshold level and the career (P<0.01).

하악에 발생한 과잉치의 치험례 : A CASE REPORT

박정아,양규호,,최남기,김선미,장희숙 大韓小兒齒科學會 2005 大韓小兒齒科學會誌 Vol.32 No.4

과잉치는 정상치판(dental lamina)의 과도한 증식이 결과로 발생되어, 가족적 성향을 보이며, 쇄골두개이형성(Cleidocranial dysplasia), Gardner 증후군 등의 여러 질환과 관련되어 나타나기도 한다. 그 빈도는 유치열에서 0.3~0.8%, 영구치열에서 1.0~3.5% 이고, 남성에서 호발되며(2:1), 상악에서 더 많이 발생한다(9:1). 상악에서는 mesiodens라고 불리는 중절치 사이의 위치가 가장 흔한 부위이고, 그 다음은 fourth molar와 측절치 부위이다. 하악에서는 소구치 부위가 가장 흔한 부위이고 전치부위에서는 약 2%로 매우 드물게 발생한다. 과잉치의 만기 잔존은 치간 이개, 인접한 치아의 맹출 장애, 치근 흡수 등을 야기하고 과잉치와 관련되어 함치성 낭종이 발생될 수 있으므로 조기진단과 적절한 치료가 중요하다. 본 두 증례는 비교적 드물게 나타나는 하악에 발생한 과잉치로, 하악 전치부와 소구치부에 발생한 과잉치를 발거하고 교정치료를 시행하여 양호한 결과를 얻었기에 보고하는 바이다. Supernumerary tooth was resulted from excessive proliferation of dental lamina and associated with familial tendency and a congenital syndrome such as Cleidocranial dysostosis or Gardner's syndrome. Incidence reports identify a range of 0.3~0.8% in primary dentition. 1.0~3.5% in permanent dentistion with males being affected twice as frequently as females. maxilla nine times as frequently as mandible. The most common supernumeraty tooth is the mesiodens, which located between the maxillary central incisors, and the next common site is the fourth molar and lateral incisors. Supernumerary teeth are uncommon in the mendible, but premolars are the most common supernumerary teeth and occurrence is very rare in the incisor region of the mandible of possibility of diastema and cruption failure displacement. rotation of the associated permanent teeth, root resorption and dentigerous cyst with presence of the supernumerary teeth. In this two case, one supernumerary tooth located in the mandibular incisor region, the other supernumerary tooth located in premolar region. We could get normal alignment of mandibular dentition by extraction and orthodontic treatment.

대전에서 연중 태양광선의 UVA와 UVB양에 대한 조사 (예비보고)

박장규,김경훈,이우재,서기범 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

Ultraviolet A(355 nm) and ultraviolet B(290 nm) doses were measured at Taejon from March to September, 1993, on four different weather conditions(clear, relatively clear, relatively cloudy and cloudy). And the results were compared with the doses of Kongju area measured in 1985. The followings were the summary of the findings. 1. UVA(1.98± 0.35 × 10 exp(-3) w/㎠) and UVB(17.62+ 5.72 X 10 exp(-6) w/㎠ doses were peak at noon on clear weather. 2. Average doses of UVA(2.36±0.70 × exp(-3) w/㎠) and UVB(24.28±8.83 × exp(-3) w/㎠) were peak at noon in August on clear weather. 3. The doses of UVA and UVB were influenced by yellow sand, fog and other pollutants. 4. The doses of UVA on clear weather in Daejoen were lower than Kongju about 40%, in contrast those of UVB were not different in statistical values.

대상포진에 대한 Isoprinosine의 치료에 대한 임상연구

박장규,한효수 충남대학교 의과대학 지역사회의학연구소 1984 충남의대잡지 Vol.11 No.2

In order to estimate the effectiveness of isoprinosine on herpes zoster, the authors selected 83 patients with herpes zoster from October, 1980 to January, 1984 at Chungnam National University Hospital. Among the patients, 54 patients participated in the drug trial. No substantial differences between the groups treated with isoprinosine and symptomatic therapy could be seen in the duration of treatment.

일부 도시지역 노인들의 우울과 일상생활능력에 관련된 요인

박원규,이태용,정용준,오장균,이동배,조영채 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

This study was performed to provide the basic data and related factors available for the assessment of the degree of ADL and depression among older persons, manifesting their physical and psychological status. The subjects included the old people aged more than 65 years old who reside in urban areas. The interviews were delivered to 693 individuals in Taejon metropolitan city during the two-month period from June to July, 2000, and Zung Self-Rating Depression Scale and IADL developed by Older American Resources and Services of Duke medical college, were employed for the assessment of depression and IADL, respectively. The collected data were statistically processed by SPSSWIN(ver 10.0) and led to the following results. The degree of depression among 635 subjects showed that 26.6% had mild depression, 8.2% moderate and 0.6% severe while 64.6% were normal. In terms of IADL, 6.9% had impossible IADL when not aided by others, 37.0% needed some help, 56.0% possible IADL, and the higher depression scores, the significantly higher IADL scores. Based on general characteristics, depression scores were significantly higher in the female group, the older, the lower educated, the ones without cohabitants, without a spouse, without making expenses of living on their own, and IADL scores were lower, meaning the lower capability for performing daily activities, in the male group, the older, the higher educated, the group without a spouse, without making expenses of living on their own. Based on daily activities and psychological characteristics, depression scores were higher in the group who don't go out, who don't have recreational or friendly gatherings, who aren't satisfied with the lives of the past or present, who have a sense of isolation, and who don't have the will to live, and IADL scores were lower in the group who don't go out, who don't have recreational or friendly gatherings, who aren't satisfied with the lives of the past or present, who have a sense of isolation. and who don't have the will to live. Multiple regression analysis revealed that the explanatory variable having effects on depression symptoms included, with the explanatory power of 57.5%, the confidence in life, the degree of education, the subjective index of health, the sense of isolation, the exercise, the degree of IADL, the gender, the level of satisfaction with life, whether they eat breakfast or not, the concern about life, the smoking, the going out, the presence of spouse or not. The explanatory variables having effects, with the explanatory power of 28.9%, on IADL scores included the degree of depression symptoms, the age, the presence of friends or not, the frequency of outgoing, the level of education, the degree of obesity, the confidence in life, the level of satisfaction with life, the drinking or not. The study results showed that the higher depression scores had a tendency to be associated with the decreased capabilities of performing daily activities, and that the factors related to depression and/or IADL, included the confidence in life, the level of education, and the level of satisfaction with life. However, the more detailed and decisive results on the factors related to depression and IADL of the older persons are considered to require continuing efforts and comparisons among a variety of the older population.

알레르기성질환의 기인항원에 관한 연구

박장규,구자경 충남대학교 의과대학 지역사회의학연구소 1986 충남의대잡지 Vol.13 No.2

To fine out the offending allergens in Chungnam province, we performed skin test with 196 diagnostic allergens (Bencard®) in 83 cases of allergic rhinitis and 26 cases of chronic urticaria from August 1982 to August 1986 at the dermatologic OPD. of Chungnam National University Hospital. The results were: 1. The positive reaction of the skin test to the diagnostic allergens in the cases of the allergic rhinitis and chronic urticaria were 91.6% and 80.8%, respectively. 2. In allergic rhinitis, 25% showed the positive reaction to single allergen and 66% to compound allergens and the offending allergens were D. farinae (56.0%), D. pteronyssinus(43.4%), house dust (35.5%), cat fur (30.3%), hay dust (22.3%) in order. 3. In chronic urticaria, 23% showed the positive reaction to single allergen and 58% to compound allergens and the offending allergens were D. farinae (33.3%), mosquito (33.3%), D. pteronyssinus (24%), mixed threshings (24%), maize pollen (24%) in order.

자극성 물질이 첩포시험 결과에 미치는 영향에 대한 연구

박장규,이우재,김경훈,서기범,이증훈 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

We studied the effects of irritants on the positive patch test sites in 6 volunteers. We firstly performed the patch test with 2, 4, 6, 8, 10% sodium lauryl sulfate on the back of 22 volunteers. Allergens (thimerosal, mercury ammonium chloride) were applied in duplicate, and 24 hours later they were removed and sodium lauryl sulfate was applied for a further 24hours to one set of patches. Response of allergen alone were measured at 24 hours, 48 hours, 72 hours, 120hours, 140hours and the degree of inflammation of the other site(allergen + irritant) was graded 30 minutes, 24, 48 and 72 hours later according to International Contact Dermatitis Research Group. The results were as follows 1. Twenty volunteers(90.9%) showed irritation sign on the patch sites with 6% sodium lauryl sulfate. 2. In the results of patch test in 6 cases with positive allergen sites, 5 cases showed the similar results with those of previous patch test (reproducibility = 83 %) 3. When we assessed the patch test results according to ICDRG, the results of patch tests after application with irritants on previous positive allergen slites did not show stronger responses than those of positive allergen alone 4. The results of patch test after application with irritants on previous negative allergen did not show erythema. It seems that the effect irritant application of lower concentration than irritant dose not influence the response to the allergen concentration than to cause erythema, on the response of allergen