악골에 발생한 석회화 치성낭의 임상 및 방사선학적 고찰

박창서,김기덕,윤혜림 大韓口腔顎顔面放射線學會 1996 Imaging Science in Dentistry Vol.26 No.2

Nine cases presented with a calcifying odontogenic cyst to the Dental Hospital of the College of Dentistry, Yonsei University, from January 1987 to September June, 1996, Clinical or histopathological findings were observed according to each radiologic criteria. The results obtained are as follows: 1. The male to female ratio was 2:1 with a mean age of 25 years. 2. The radiographic appearences of nine cases were well-defined radiolucent lesions in which eight cases were shown unilocular lesions and only one lesion was seen multilocular lesion. 3. Radiologically, three of nine cases were pure radiolucent lesions and others, six cases were radiolucent contained a variable amount of radiopaque material. 4. Histologically, two cases were classified simple cyst, five were cyst associated odonoma, two were neoplastic type. 5. Histlolgical findings according to the radiological classification, two of three radiolucenct lesions were simple cysts; another was a cyst associated with odontoma. While, four of six radiologic mixed lesions turned out to be a cyst associated with odontoma, two was the neoplastic type.

U-rantac^ⓡ의 위산 분비억제 효과에 대한 연구

윤완희,장일성,박혜덕 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.1

Ranitidine HC1(U-rantac^ⓡ) is a highly effective, rapidly acting histamine H2-receptor antagonist. It inhibit basal and stimulated secretion of gastric acid, reducing both the volume, and the acid pepsin content of the secretion. Now, It has been widely used for treatment of the peptic ulcer. We has investigated the effect of Ranitidine HC1 in the peptic ulcer and stomach cancer in 62 patients who had been admitted to the Department of General Surgery, Chungnam National Universtity Hospital from Jan. 1987 to Apr. 1987. The following results were obtained: 1. The prevalent age in duodenal ulcer was fourth decade, gastric ulcer, fifth decade, and stomach cancer, sixth decade, respectively. 2. The male to female ratio in duodenal ulcer was 2. 8 : 1, gastric ulcer, 2 : 1, and stomach cancer, 1:1. 3. After intramuscular injection of Ranitidine HCl in duodenal ulcer, volume of gastric secretion was decreased in 31ml/hr (36%) in male and 20m1/hr (33%) in female, and gastric acidity was decreased in 3. 5mEq/hr (54. 4%) and 2. OmEq/hr (48.8%), respectively. In gastric ulcer, the volume of gastric secretion was decreased in 14ml/hr (21. 9%) in male and 4m1/hr (7. 7%) in female, and the gastric acidity was decreased in 0. 9mEq/hr (39.0%) and 0. 6mq/hr(23. 1%), respectivly. In stomach cancer, the volume of the gastric secretion was decreased in 17ml/hr (28. 8%) in male and 15ml/hr (25.9%) in female, and the gastric acidity was decreased in 0.5mEq/hr (15.6%) and 0.6mEq,/hr (19.4%), respectively.

화농성 간농양의 외과적 배액술 및 경피 삽관 배액술

윤완희,노승무,박혜덕 충남대학교 의과대학 지역사회의학연구소 1988 충남의대잡지 Vol.15 No.2

This report is a clinical analysis and study of therapeutic effect between the surgical and percutaneous catheter drainage of 25 cases of pyogenic liver abscesses who were admitted and treated at the Chungnam National University Hospital from February 1986 to July 1988 and the results were as follows 1. The common clinical symptoms and signs in order of frequency were fever(92.0%), R.U.Q. pain(84.0%), anorexia(80.0%), and malaise (76.0%). 2. The liver function test were helpful in diagnosis such as increased alkaline phosphatase (92.0%), leukocytosis(88.0%), increased GCT(80.0%), and increased prothrombin time(68.0%). 3. The liver abcess located in the right lobe in 18 cases (72.0%), left lobe in 4 cases (16.0%), and both lobes in 3 cases(12.0%). And multiple abscesses were found in 6 cases (24.0%). 4. 10 cases of liver abscesses were drained surgically, and percutaneous catheter drainage was performed in 15 cases. 5. Mean days when afebrile after surgical drainage were 4 days, and after percutaneous catheter drainage were 7 days. 6. Mean hospital stay after surgical drainage were 26 days, and after percutaneous catheter drainage were 22 days. 7. Cure rate after surgical drainage was 100.0%, and after percutaneous catheter drainage was 86.7%.

성인 서혜부탈장의 임상적 고찰

윤완희,박혜덕 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.2

This report is a clinical analysis and study of 48 cases of adult inguinal hernias who were admitted and treated at the Department of Surgery, Chungnam National University Hospital from October 1983 to September 1987 and the results were as follows: 1. The age distribution was most prevalent over 51 years(62.5%), and the ratio between male and female was 23: 1. 2. Indirect type was noted in 37 cases(77.1%), direct type in 7 cases (14.6%), and combined type in 4 cases(8.3%). 3. Inguinal hernia found on the right side in 34 cases(70.8%), left side in 11 cases(22.9) , and bilateral in 3 cases(6.3%). 4. The cardinal symptoms and signs were bulging on the inguinal region (100.0%), and scrotal swelling(43.8%). 5. Incarcerated hernia was noted in 6 cases(12.5%), strangulation in 1 case(2. 1%), and hydrocele was combined in 5 cases(l0.4%). 6. 35 cases(72.9%) of all hernias were repaired by Bassini method, and 13 cases(27.1%) by McVay method. 7. Sliding hernia accounted for 16.7% of all cases. Urinary bladder, cecum, and sigmoid colon were involved. 8. The average duration of postoperative hospitalization was 7 days. 9. The postoperative complications were noted in 2 cases(4.2%), and there was no recurrence after herniorrhaphy.

버섯의 자외선조사와 조리조건에 따른 Vit.D_2 와 Vit.B_2 함량의 변화

박희옥,오혜숙,윤선 한국식생활문화학회 2001 韓國食生活文化學會誌 Vol.16 No.5

This study was to investigate the effect of ultraviolet rays, soaking, boiling and baking to ergocalciferol(Vit.D_2) and riboflavin(Vit.B_2) contents of mushrooms, Lentinus edodes, Pleurotus ostreatus and Agaricus bisporus. The results were as follows: 1. Mushrooms were exposed to ultraviolet rays, Lentinus edodes : 10J/㎠, Pleurotus ostreatus : 2J/㎠ and Agaricus bisporus : 2J/㎠. 2. Before exposing to ultraviolet rays, the ergocalciferol contents of mushrooms were all 0㎍/g dry base, but after exposing to it , those of Lentinus edodes, Pleurotus ostreatus and Agaricus bisporus were 222.50±5.30㎍/g dry base, 150.90±6.60㎍/g dry base and 23.98±1.20㎍/g dry base, respectively. 3. Before and after exposing to ultraviolet rays, the riboflavin contents of Lentinus edodes, Pleurotus ostreatus and Agaricus bisporus were 18.22±0.71㎍/g dry base and 11.72±0.50㎍/g dry base, 4.57±0.20㎍/g dry base and 3.26±0.15㎍/g dry base, and 37.42±1.20㎍/g dry base and 27.33±2.10㎍/g dry base, respectively. 4. The ergocalciferol contents of mushrooms according to boiling time were not significantly different but the riboflavin contents of them were decreased according to the increase of boiling time. 5. The ergocalciferol and riboflavin contents of mushrooms were decreased according to the increase of NaCl concentration and baking temperature. 6. The ergocalciferol content of Lentinus edodes after a short time soaking at 80℃ was higher than a long time soaking at 20℃, 40℃ and 60℃.

기술역량, 혁신성, 관리역량이 구매IOS성과에 미치는 영향

박해철,김기윤,나관식 한국정보사회진흥원 2006 정보화정책 Vol.13 No.2

IOS(Inter-Organizational Information Systems)는 전통적인 제조업을 비롯한 모든 산업분야에서 폭넓게 활용되고 있으며, 광범위하게 흩어져 있는 공급자, 유통망, 고객들을 연결해 주는 주문시스템이 일반적이다. 실무적으로는 EDI나 SCM 등과 같은 형태로 구현되고 있는 이 IOS가 최근 들어 이들 조직 간의 거래활동을 혁신적으로 변화시키고 있지만, 실제 적용에 도움을 줄 수 있는 구매성과에 관련된 연구는 거의 이루어지지 않고 있다. 따라서 본 논문의 연구목적은 기술역량, 혁신성, 관리역량이 구매IOS 성과에 미치는 영향을 검정하고자 하는 것이다. 이를 위해서 기존 연구로부터 네 개의 가설을 도출하여 연구모형을 수립하였고, 구조방정식모형으로 이를 검정하였다. 검정결과 혁신성과 관리역량은 구매IOS품질에 직접적으로 관련이 되어 있으며, 이 구매IOS품질은 구매성과를 향상시키는 것으로 나타났다. 하지만 기술역량과 구매IOS품질과의 관계에서는 기업 규모에 따라 상이한 결과를 보였다. 이 결과에 의하면 대기업의 경우 중소기업과는 달리 기술역량이 중요한 요인인 것으로 검정되었으므로, 개별기업이나 관련기관에서 IOS 구축을 위한 정보기술 투자정책 수립 시에는 기업규모에 따라 차별화된 접근방법이 요구된다.

HM7 세포 표면 점액이 국소침윤 및 전이에 미치는 영향에 관한 연구

윤완희,박혜덕,임규,황병두 충남대학교 생물공학연구소 1998 생물공학연구지 Vol.6 No.-

Mucinous colorectal cancers have a poorer prognosis than which colorectal cancer produce low amount of mucin, but the exact mechanism is not well understood. The present study was undertaken to elucidate the exact mechanism of invasion and metastasis of high mucin producing colon cancer cells using mucin glycosylation inhibitor, benzyl-a-N-acetylgalactosamine. Materials and Methods: To evaluate the effect of glycosylated mucin on invasion and metastasis, in vitro invasion, metalloproteinases(MMPs) activity, cell-matrix protein binding, cell-cell aggregation, as well as endothelial leukocyte adhesion molecule(ELAM-1) binding and cell surface expression of various mucin related antigens were analyzed. Results: MMPs activity in conditioned medium and invasion of ECM-coated porous filters by benzyl-a-GalNAc treated HM7 cells were decreased. There was no difference between control and treated HM7 cells in terms of matrix protein binding assay, but treated HM7 cells showed higher homotypic cell adhesion. The binding activity of treated HM7 cells to ELAM-1 was significantly decreased and fixed cell binding of MoAb SNH-3, 19-9(specific for sialyl-Lewis X and sialy-Lewis A) were also significantly decreased. Conclusion: These results suggest that glycosylated mucin modulates ELAM-1 binding, MMPs activity and homotypic cell adhesion, therefore enhance invasive and metastatic properties of human colon cancer cells.

소아에서 알레르기 증상과 알레르겐 특이항체와의 관련성

박준수,안현철,남해선,황규윤 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

To evulate usefulness of application of MAST-CLA to identify allergens in children, authors conducted MAST-CLA allergen-specific IgE assay and collected allergy related symptoms in 88 pediatric allegic patients diagnosed at Soonchunhyand University Chunan Hospital during October 1998 through January 2000. The mean (SD) age of study subjects was 8.8(3.2) years. The frequent allergic symptoms were rhinorrhea (40.9%), nasal stuffiness(38.6%), cough(36.4%), sneezing(35.2%), and itching sensation(28.4%) in order. Among them, 56.8% revealed at least more than one allergen specific IgE by MAST-CLA. The three most frequent specific allergens were Dermatophagoides farinae(52.3%) Dermatophagies pteronyssinus(51.1%), and house dust(35.2%). The positive rate of allergen specific IgE was increased by increasing age(P<0.001). Among the symptoms the sneezing showed most high positive rate of allergen specific IgE(80.7%) and total IgE(80.7%). In multivariate analysis, significant odds ratios remained(adjusted OR-4.66, P=0.004). In conclusion, our data suggest that allergic symptoms are associated with allergen-specific IgE using MAST-CLA assay, which is an useful measure for identification of causative allergens in pediatric allergen patients.

Hymecromone 복합제제(Pasmital^�)의 만성담낭염과 Oddi 괄약근 이완 효과에 대한 연구

윤완희,박혜덕,장일성 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.1

Experience at the Cleveland Clinic is that approximately 65 to 70% of patients with symptomatic gallstones are diagnosed as having chronic cholecystitis. Of the group of patients with chronic cholecystitis, approximately 20% have mild, vague symptoms. If the episodes of cholecystitis are not severe, recurrent, and progressive in their intensity or they have poor operative risk, medical treatment include antispasmodic medication is often tried. The purpose of this study was to investigate the effect go hymecromoe combination product(Pasmital^??) given orally in chronic cholecystitis as a medical treatment and to evaluate the pressure changes in the bile duct in postoperative patients received Pasmital^??. 1. Satisfactory symptomatic improvement (Visick grades Ⅰor Ⅱ) was achieved 75.0% after 1 week Pasmital^?? administration and 87.5% after 3 weeks Pasmital^?? administration. 2. There was a mean reduction of bile duct pressure of 31.2% in basal pressure and 36.7% in opening pressure following Pasmital^?? administration. 3. No side effects or abnormal laboratory values attributable to the Pasmital^?? were observed.

국내산 중하(Metapenaeus joyneri) 내 주알레르겐 규명 : 가열 및 소화액에 의한 변화

윤성호,김현아,김현미,최정희,서창희,남동호,김윤근,민경업,박해심 대한알레르기학회 2004 천식 및 알레르기 Vol.24 No.2