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A rare case of extensive papillary muscle calcification in senile cardiac calcification syndrome
김은진;송봉근;강민호;손형래;홍수민;박동원;허승혜;김계연;최석구 인제대학교 2011 仁濟醫學 Vol.32 No.-
광범위 유두근 석회화는 흔하지 앉으며, 원인과 임상적 중요성에 관한 문헌만 드물게 찾아볼 수 있다. 반면에 작은 석회 침착은 노인에서 흔하며 심장 첨부에 주로 나타난다. 유두근 석회화는 관상동맥질환, 확장성 심근병증, 승모관 질환, 고칼슘혈증, 그리고 말기신부전에서 인산칼슘의 중가와 연관성이 있다. 저자는 심장초옴파와 MDCT를 통해 진단된 전외측 유두근의 광범위 석회화의 드문 사례가 있어 보고한다.
배지의 무기염류와 sucrose 농도가 감자의 기내 shoot 증식과 기내경 삽목묘의 생존율에 미치는 영향
김희곤,임순희,안장순,송창길,박미경,강봉균 全南大學校 農業科學技術硏究所 1999 農業科學技術硏究 Vol.34 No.-
감자의 virus-free 기내경 삽목묘의 효율적인 대량 생산 체계의 확립을 위하여 생장점 배양으로 얻어진 감자의 기내경의 증식과 기내경의 순화삽목을 실시한 결과는 다음과 같다. 초대배양에서는 염류농도와 sucrose 농도가 높을수록 양호하였다. 즉, MS나 2MS에 sucrose를 6% 첨가한 배지에서 튼튼한 기내경이 생산되었다. 계대배양에서는 sucrose 농도가 높을수록 줄기의 길이는 단축되고 굵기는 커졌으며 생체중은 염류농도와 관계없이 3%의 sucrose가 첨가된 배지에서 무거웠다. 이들 유식물체의 경절을 삽목한 결과 계대배양 배지의 sucrose농도가 6%인 배지에서 생존율이 높은 경향이었다. In order to establish a mass propagation system of potato planting material, in vitro multiplication of virus-free shoot originated from meristem culture and sucrose concentrations on survival of cutting of the in vitro stem tried with various media containing different levels of MS salts(0.5x, 1x and 2x) and sucrose(1.0, 3.0, 6.0%), and the effects of MS salts elements were evaluated. Higher level of sucrose in the initial culture media favored the shoot growth, that is, both of 1MS and 2MS media containing 6.0% sugar produced stouter shoots. Higher level of sucrose in the subculture media also favored the development of compact stout shoots, but biomass production in terms of fresh weight was high on the media containing 3.0%sucrose, regardless of MS salts concentration. The survival rate of cuttings made of the in vitro stem segments tended to be higher in those obtained from subculture media containg 6.0%sucrose.
Cardiac Amyloidosis with Progressive Heart Failure Managed by Heart Transplantation : A Case Report
Sohn, Hyung-Rae;Song, Bong-Gun;Kang, Min-Ho;Kim, Eun-Jin;Jeong, Seong-Yeon;Hong, Su-Min;Jung, Hyun-Gul;Choi, Suk-Koo 인제대학교 2011 仁濟醫學 Vol.32 No.-
아밀로이드의 심근 침윤은 심각한 예후를 초래할 수 있는 진행성 심근병증 뿐만 아니라 울혈성 심부전, 심장 판막 질환, 부정맥 등과 같은 다양한 심장질환을 일으킬 수 있다. 우리는 처음에 심근 아밀로이드증으로 내원하였으나 신드롬 X로 잘못 진단되었던 환자가 재발성 흉통 및 진행성 심부전으로 인해 심장 이식을 시행한 증례가 있어, 이를 보고하는 바이다.
Catastrophic Massive Intracardiac Thrombus in a 40-year-old Patient with Dilated Cardiomyopathy
Gi Jung Jeon · Bong Gun Song · Tae Hun Kim · Hye Jin Yang · Bong Oh Ma · Yong Hwan Park · Gu Hyun Kang · Woo Jung Chun · Ju Hyeon Oh 조선대학교 의학연구원 2011 The Medical Journal of Chosun University Vol.36 No.4
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Combined Dual Channel Impedance/pH-metry in Patients With Suspected Laryngopharyngeal Reflux
( Bong Eun Lee ),( Gwang Ha Kim ),( Dong Yup Ryu ),( Dong Uk Kim ),( Jae Hoon Cheong ),( Dong Gun Lee ),( Geun Am Song ) 대한소화기기능성질환·운동학회 2010 Journal of Neurogastroenterology and Motility (JNM Vol.16 No.2
Background/Aims: Laryngopharyngeal symptoms of gastroesophageal reflux disease (GERD) such as globus sensation, hoarseness and chronic cough are becoming increasingly recognized. This study was aimed to investigate the diagnostic usefulness of combined dual channel multichannel intraluminal impedance (MII)/pH-metry in `off-proton pump inhibitor (PPI)` patients with suspected Laryngopharyngeal reflux.Methods: Ninety-eight patients with Laryngopharyngeal symptoms of GERD were included. All patients were `off-PPI` state for at Least 2 weeks prior to the study, and underwent endoscopy and dual channel combined MII/pH-metry. Results: The mean age of the patients was 49.8 ± 10.9 years and there were 44 males (44.9%). Fifty-three patients (54.1%) showed pathologic gastroesophageal reflux (GER). Combined dual channel MII/pH-metry achieved highest diagnostic yield of 49.0% and diagnostic yield of single channel combined MII/pH-metry was 37.8%. Addition of MII to standard pH-metry increased twofold of the diagnostic yield for detecting GER. Among 37 patients (37.8%) who had pathologic GER being detected by MII/pH-metry, 19 patients (19.4%) had nonacid GER (nonacid GER group) while 18 patients (18.4%) had acid GER (acid GER group). Pathologic GER group, as classified by MII/pH-metry showed more frequent globus sensation than nonpathologic GER group. Acid GER group had more proximal reflux than nonacid GER group, especially in the upright position.Conclusions: In this study, combined dual channel MII/pH-metry showed the highest diagnostic yield for detecting GER. This technique can be performed primarily to accurately diagnose Laryngopharyngeal reflux disease and exclude other causes of Laryngopharyngeal symptoms.(J Neurogastroenterol Motil 2010;16:157-165)
Ju, Bong-Gun,Solum, Derek,Song, Eun Joo,Lee, Kong-Joo,Rose, David W.,Glass, Christopher K.,Rosenfeld, Michael G. Elsevier 2004 Cell Vol.119 No.6
<P><B>Abstract</B></P><P>Switching specific patterns of gene repression and activation in response to precise temporal/spatial signals is critical for normal development. Here we report a pathway in which induction of CaMKIIδ triggers an unexpected switch in the function of the HES1 transcription factor from a TLE-dependent repressor to an activator required for neuronal differentiation. These events are based on activation of the poly(ADP-ribose) polymerase1 (PARP-1) sensor component of the groucho/TLE-corepressor complex mediating dismissal of the corepressor complex from HES1-regulated promoters. In parallel, CaMKIIδ mediates a required phosphorylation of HES1 to permit neurogenic gene activation, revealing the ability of a specific signaling pathway to modulate both the derepression and the subsequent coactivator recruitment events required for transcriptional activation of a neurogenic program. The identification of PARP-1 as a regulated promoter-specific exchange factor required for activation of specific neurogenic gene programs is likely to be prototypic of similar molecular mechanisms.</P>