http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
혈액투석 환자의 신성 빈혈에 대한 Recombinant Huyman Erythropoietin 의 효과
강원택(Won Tak Kang),서재석(Jae Suk Suh),황금만(Keum Man Hwang),박창현(Chang Hyun Park),박성광(Sung Kwang Park),강성귀(Sung Kyew Kang) 대한내과학회 1992 대한내과학회지 Vol.43 No.3
N/A Anemia is a major and predictable complication of chronic renal failure. When end-stage renal failure evolves, the anemia is frequently severe and often impairs rehabilitation despite adequate dialysis therapy. Now we administered recombinant human erythropaietin (rhuEPO) to 8nemic patients with end-stage renal failure who were undergoing hemodialysis. The recombinant human erythropoietin was given intravenously three or two times a week after dialysis. Transfusion requirements, hematocrit, ferrokinetics and adverse reactions were monitored. In 8patients treated for 16weeks, hemoglobin increased from initial mean (±SD) 6.86±0.68g/di to 9.36±0.87g/dl (p<0.01). Hematocrit increased from initial mean 19.4±2.1% to 28.0±2.6(p<0.01). Serum iron decreased from initial mean 202.6±77.9㎍/dl to 67.4±20.2㎍/dl (p<0.01) and ferritin decreased but it was not significant stastically (p>0.05). Uric acid increased from initial mean 6.5±1.1mg/dl to 8.3±0.9mg/dl (p<0.05). Adverse reactions was one hypertension acceleration and chest pain, but was no vascular access thrombosis. These results suggest that Recombinant Human Erythropoietin is effective and may be eliminate the need for transfusion with their risks of immunologic sensitization, infection and iron overload and can restore the hematocrit to normal in anemic patients of end-stage renal failure.
황금만,이승렬,이수택,이용철,이양근 대한응급의학회 1993 대한응급의학회지 Vol.4 No.1
Suicidal tendency following drug intoxication is increased according to heightening social stress which is resulted from social complexity and development. A variety of drugs became available and clinical aspects of drug intoxication became rather variable, but recent reports about drug intoxication is rare, so we analyzed about 458cases of drug intoxication visited to emergency room of Chonbuk National University Medical School during recent 2 years from Dec. 1990 to Nov. 1992 and following results were obtained. 1. The total number of cases of acute drug intoxication was 458 which is 1.8% of total patients of emergency room. 2. There was no sexual difference in incidence, but the highest incidence of age group was in 2nd and 3rd decade age group(43.3%) 3. Monthly incidence was highest in July. Higher frequency was observed in summer season. 4. The most common cause of drug intoxication was suicide(63.1%) and the others were accidental, spray, therapeutic, others, unknown in orders. 5. The most common drug of intoxication was insecticides(44.8%) and the others were miscellaneous, sedatives, herbicides, rodenticides, herb, unknown in orders. 6. Most of the patients(80.7%)came to the Hospital within 5 hours after ingestion of drugs. 7. Main clinical symptoms were impairment of consciousness, nausea and vomiting, abdominal pain and irritability. Main physical signs were tachypnea, tachycardia, increased blood pressure and miosis. Such a symptom and sign was more prominent in organophosphate intoxication. 8. Patients requiring longer management than 7days were observed in 8.3% and most of them were insecticides and acetic acid ingestion. 9. Complications were developed in 19.1% of the cases and the most common complication was respiratory failure, others were mucosal ulcerations, aspiration pneumonia in orders. 10. The overal mortality rate of the cases was 11% and mortality rate was unknown, herbicides, pesticides in orders.
상부위장관 대량 출혈을 동반한 Menetrier`s Disease 1예
김종훈,이창환,이동근,이용철,안득수,김대곤,이수택,송하숙,황금만 대한소화기학회 1992 대한소화기학회지 Vol.24 No.4
In Menetriers disease, the gastric mucasal hypertrophy is so great that the rugae looks like convolutions of the brain. Although this gross appearance is common to all cases of Menetriers disease, either the gastric glandular elements or the superficial epithelial elements may predominate; acid secretion may be high, normal, or low; and hypoproteinemia may or may not be present. There is no consensus about which of these features define the disease. The main abnormality is a remarkable hyperplasia of the mucous surface and foveolar cells, but its pathogenesis and pathophysiology are poorly understood. Menetrier's disease is rarely cited as a cause of hematemesis, although this complication is recognized and should be considered in any case of hematemesis in which rugal hypertrophy is found at gastrofiberscopy or upper gastrointestinal series (UGIS). Recently, we experienced a 37 year old man who presented with massive hematemesis and hypoproteinemia. Menetriers disease was suggested by laboratory findings, gastrofiberoscopy and UGIS. Massive UGI bleeding had repetitively occurred five times in spite of conservative management, so total gastrectomy was performed. The pathologic findings are consistent with those of Menetriess disease such as thickened hyperplastic mucosa of the gastric fundus with characteristic cystic dilatation of the deeper crypts. Thereafter, the patient have recovered in good general condition and UGI bleeding was stopped. We present a rare case of Menetries disease associated with masive UGI bleeding and a brief review of clinical and pathologic pictures and management.